-
1
-
-
0009163660
-
-
Horace Liveright, New York
-
Eliot T.S. The Waste Land 1922, Horace Liveright, New York.
-
(1922)
The Waste Land
-
-
Eliot, T.S.1
-
2
-
-
77956745716
-
Catalysis by micelles, membranes and other aqueous aggregates as models of enzyme action
-
Kunitake T., Shinkai S. Catalysis by micelles, membranes and other aqueous aggregates as models of enzyme action. Adv Phys Org Chem 1981, 17:435-487.
-
(1981)
Adv Phys Org Chem
, vol.17
, pp. 435-487
-
-
Kunitake, T.1
Shinkai, S.2
-
3
-
-
1842582944
-
Biomimetic reactions catalyzed by cyclodextrins and their derivatives
-
Breslow R., Dong S.D. Biomimetic reactions catalyzed by cyclodextrins and their derivatives. Chem Rev 1998, 98:1997-2012.
-
(1998)
Chem Rev
, vol.98
, pp. 1997-2012
-
-
Breslow, R.1
Dong, S.D.2
-
4
-
-
84990085627
-
The design of molecular hosts, guest and their complexes
-
Cram D.J. The design of molecular hosts, guest and their complexes. Angew Chem Int Ed Engl 2003, 27:1009-1020.
-
(2003)
Angew Chem Int Ed Engl
, vol.27
, pp. 1009-1020
-
-
Cram, D.J.1
-
5
-
-
0033791659
-
Critical analysis of antibody catalysis
-
Hilvert D. Critical analysis of antibody catalysis. Annu Rev Biochem 2000, 69:751-793.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 751-793
-
-
Hilvert, D.1
-
6
-
-
77949860707
-
Designing artificial enzymes by intuition and computation
-
Nanda V., Koder R.L. Designing artificial enzymes by intuition and computation. Nat Chem 2010, 2:15-24.
-
(2010)
Nat Chem
, vol.2
, pp. 15-24
-
-
Nanda, V.1
Koder, R.L.2
-
7
-
-
84878025107
-
Computational enzyme design
-
Kiss G., Çelebi-Ölçüm N., Moretti R., Baker D., Houk K.N. Computational enzyme design. Angew Chem Int Ed 2013, 52:5700-5725.
-
(2013)
Angew Chem Int Ed
, vol.52
, pp. 5700-5725
-
-
Kiss, G.1
Çelebi-Ölçüm, N.2
Moretti, R.3
Baker, D.4
Houk, K.N.5
-
8
-
-
65249171530
-
Design of protein-interaction specificity gives selective βZIP-binding peptides
-
Grigoryan G., Reinke A.W., Keating A.E. Design of protein-interaction specificity gives selective βZIP-binding peptides. Nature 2009, 458:859-864.
-
(2009)
Nature
, vol.458
, pp. 859-864
-
-
Grigoryan, G.1
Reinke, A.W.2
Keating, A.E.3
-
9
-
-
33947086265
-
Physical organic chemistry of benzisoxazoles. II. Linearity of the Bronsted free energy relationship for the base-catalyzed decomposition of benzisoxazoles
-
Kemp D.S., Casey M.L. Physical organic chemistry of benzisoxazoles. II. Linearity of the Bronsted free energy relationship for the base-catalyzed decomposition of benzisoxazoles. J Am Chem Soc 1973, 95:6670-6680.
-
(1973)
J Am Chem Soc
, vol.95
, pp. 6670-6680
-
-
Kemp, D.S.1
Casey, M.L.2
-
10
-
-
0029793086
-
Off-the-shelf proteins that rival tailor-made antibodies as catalysts
-
Hollfelder F., Kirby A.J., Tawfik D.S. Off-the-shelf proteins that rival tailor-made antibodies as catalysts. Nature 1996, 383:60-63.
-
(1996)
Nature
, vol.383
, pp. 60-63
-
-
Hollfelder, F.1
Kirby, A.J.2
Tawfik, D.S.3
-
11
-
-
84888034901
-
Precision is essential for efficient catalysis in an evolved Kemp eliminase
-
Blomberg R., Kries H., Pinkas D.M., Mittl P.R.E., Grütter M.G., Privett H.K., Mayo S.L., Hilvert D. Precision is essential for efficient catalysis in an evolved Kemp eliminase. Nature 2013, 503:418-421.
-
(2013)
Nature
, vol.503
, pp. 418-421
-
-
Blomberg, R.1
Kries, H.2
Pinkas, D.M.3
Mittl, P.R.E.4
Grütter, M.G.5
Privett, H.K.6
Mayo, S.L.7
Hilvert, D.8
-
12
-
-
84863000087
-
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
-
Khersonsky O., Kiss G., Röthlisberger D., Dym O., Albeck S., Houk K.N., Baker D., Tawfik D.S. Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59. Proc Natl Acad Sci U S A 2012, 109:10358-10363.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 10358-10363
-
-
Khersonsky, O.1
Kiss, G.2
Röthlisberger, D.3
Dym, O.4
Albeck, S.5
Houk, K.N.6
Baker, D.7
Tawfik, D.S.8
-
13
-
-
0028869408
-
Large rate accelerations in antibody catalysis by strategic use of haptenic charge
-
Thorn S.N., Daniels R.G., Auditor M.-T.M., Hilvert D. Large rate accelerations in antibody catalysis by strategic use of haptenic charge. Nature 1995, 373:228-230.
-
(1995)
Nature
, vol.373
, pp. 228-230
-
-
Thorn, S.N.1
Daniels, R.G.2
Auditor, M.-T.M.3
Hilvert, D.4
-
14
-
-
73249139757
-
An aspartate and a water molecule mediate efficient acid-base catalysis in a talored antibody pocket
-
Debler E.W., Muller R., Hilvert D., Wilson I.A. An aspartate and a water molecule mediate efficient acid-base catalysis in a talored antibody pocket. Proc Natl Acad Sci U S A 2009, 106:18539-18544.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18539-18544
-
-
Debler, E.W.1
Muller, R.2
Hilvert, D.3
Wilson, I.A.4
-
15
-
-
0030798274
-
Catalysis of the Kemp elimination by antibodies elicitied against a cationic hapten
-
Genre-Grandpierre A., Tellier C. Catalysis of the Kemp elimination by antibodies elicitied against a cationic hapten. Bioorg Med Chem Lett 1997, 7:2497-2502.
-
(1997)
Bioorg Med Chem Lett
, vol.7
, pp. 2497-2502
-
-
Genre-Grandpierre, A.1
Tellier, C.2
-
16
-
-
79955570791
-
Design of a switchable eliminase
-
Korendovych I.V., Kulp D.W., Wu Y., Cheng H., Roder H., DeGrado W.F. Design of a switchable eliminase. Proc Natl Acad Sci U S A 2011, 108:6823-6827.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6823-6827
-
-
Korendovych, I.V.1
Kulp, D.W.2
Wu, Y.3
Cheng, H.4
Roder, H.5
DeGrado, W.F.6
-
17
-
-
84878699746
-
A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of unnatural reaction
-
Moroz O.V., Moroz Y.S., Wu Y., Olsen A.B., Cheng H., Mack K.L., McLaughlin J.M., Raymond E.A., Zhezherya K., Roder H., et al. A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of unnatural reaction. Angew Chem Int Ed 2013, 52:6246-6249.
-
(2013)
Angew Chem Int Ed
, vol.52
, pp. 6246-6249
-
-
Moroz, O.V.1
Moroz, Y.S.2
Wu, Y.3
Olsen, A.B.4
Cheng, H.5
Mack, K.L.6
McLaughlin, J.M.7
Raymond, E.A.8
Zhezherya, K.9
Roder, H.10
-
18
-
-
84904513451
-
Design of catalytically amplified sensors for small molecules
-
Makhlynets O.V., Korendovych I.V. Design of catalytically amplified sensors for small molecules. Biomolecules 2014, 4:402-418.
-
(2014)
Biomolecules
, vol.4
, pp. 402-418
-
-
Makhlynets, O.V.1
Korendovych, I.V.2
-
19
-
-
84876496466
-
Reprogramming EF-hands for design of catalytically amplified lanthanide sensors
-
Mack K.L., Moroz O.V., Moroz Y.S., Olsen A.B., McLaughlin J.M., Korendovych I.V. Reprogramming EF-hands for design of catalytically amplified lanthanide sensors. J Biol Inorg Chem 2013, 18:411-418.
-
(2013)
J Biol Inorg Chem
, vol.18
, pp. 411-418
-
-
Mack, K.L.1
Moroz, O.V.2
Moroz, Y.S.3
Olsen, A.B.4
McLaughlin, J.M.5
Korendovych, I.V.6
-
20
-
-
84867093396
-
Engineering a model protein cavity to catalyze the Kemp elimination
-
Merski M., Shoichet B.K. Engineering a model protein cavity to catalyze the Kemp elimination. Proc Natl Acad Sci U S A 2012, 109:16179-16183.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 16179-16183
-
-
Merski, M.1
Shoichet, B.K.2
-
21
-
-
0032253961
-
Theozymes and compuzymes: theoretical models for biological catalysis
-
Tantillo D.J., Chen J., Houk K.N. Theozymes and compuzymes: theoretical models for biological catalysis. Curr Opin Chem Biol 1998, 2:743-750.
-
(1998)
Curr Opin Chem Biol
, vol.2
, pp. 743-750
-
-
Tantillo, D.J.1
Chen, J.2
Houk, K.N.3
-
22
-
-
43449098518
-
Kemp elimination catalysts by computational enzyme design
-
Rothlisberger D., Khersonsky O., Wollacott A.M., Jiang L., DeChancie J., Betker J., Gallaher J.L., Althoff E.A., Zanghellini A., Dym O., et al. Kemp elimination catalysts by computational enzyme design. Nature 2008, 453:190-195.
-
(2008)
Nature
, vol.453
, pp. 190-195
-
-
Rothlisberger, D.1
Khersonsky, O.2
Wollacott, A.M.3
Jiang, L.4
DeChancie, J.5
Betker, J.6
Gallaher, J.L.7
Althoff, E.A.8
Zanghellini, A.9
Dym, O.10
-
23
-
-
77649271939
-
Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series
-
Khersonsky O., Rothlisberger D., Dym O., Albeck S., Jackson C.J., Baker D., Tawfik D.S. Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series. J Mol Biol 2010, 396:1025-1042.
-
(2010)
J Mol Biol
, vol.396
, pp. 1025-1042
-
-
Khersonsky, O.1
Rothlisberger, D.2
Dym, O.3
Albeck, S.4
Jackson, C.J.5
Baker, D.6
Tawfik, D.S.7
-
24
-
-
79952437832
-
Optimization of the in-silico-designed Kemp eliminase KE70 by computational design and directed evolution
-
Khersonsky O., Rothlisberger D., Wollacott A.M., Murphy P., Dym O., Albeck S., Kiss G., Houk K.N., Baker D., Tawfik D.S. Optimization of the in-silico-designed Kemp eliminase KE70 by computational design and directed evolution. J Mol Biol 2011, 407:391-412.
-
(2011)
J Mol Biol
, vol.407
, pp. 391-412
-
-
Khersonsky, O.1
Rothlisberger, D.2
Wollacott, A.M.3
Murphy, P.4
Dym, O.5
Albeck, S.6
Kiss, G.7
Houk, K.N.8
Baker, D.9
Tawfik, D.S.10
-
25
-
-
84863230018
-
Iterative approach to computational enzyme design
-
Privett H.K., Kiss G., Lee T.M., Blomberg R., Chica R.A., Thomas L.M., Hilvert D., Houk K.N., Mayo S.L. Iterative approach to computational enzyme design. Proc Natl Acad Sci U S A 2012, 109:3790-3795.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 3790-3795
-
-
Privett, H.K.1
Kiss, G.2
Lee, T.M.3
Blomberg, R.4
Chica, R.A.5
Thomas, L.M.6
Hilvert, D.7
Houk, K.N.8
Mayo, S.L.9
-
27
-
-
33947322034
-
Nonlinear structure-reactivity correlations. Reactivity of nucleophilic reagents toward esters
-
Jencks W.P., Gilchrist M. Nonlinear structure-reactivity correlations. Reactivity of nucleophilic reagents toward esters. J Am Chem Soc 1968, 90:2622-2637.
-
(1968)
J Am Chem Soc
, vol.90
, pp. 2622-2637
-
-
Jencks, W.P.1
Gilchrist, M.2
-
28
-
-
0014217102
-
Esterase activities of human carbonic anhydrases B and C
-
Verpoorte J.A., Mehta S., Edsall J.T. Esterase activities of human carbonic anhydrases B and C. J Biol Chem 1967, 242:4221-4229.
-
(1967)
J Biol Chem
, vol.242
, pp. 4221-4229
-
-
Verpoorte, J.A.1
Mehta, S.2
Edsall, J.T.3
-
29
-
-
0033514981
-
Rate-determining step of Escherichia coli alkaline phosphatase altered by the removal of a positive charge at the active center
-
Sun L., Martin D.C., Kantrowitz E.R. Rate-determining step of Escherichia coli alkaline phosphatase altered by the removal of a positive charge at the active center. Biochemistry 1999, 38:2842-2848.
-
(1999)
Biochemistry
, vol.38
, pp. 2842-2848
-
-
Sun, L.1
Martin, D.C.2
Kantrowitz, E.R.3
-
30
-
-
0001468012
-
Substituent effects on an antibody-catalyzed hydrolysis of phenyl-esters: further evidence for an acyl-antibody intermediate
-
Gibbs R.A., Benkovic P.A., Janda K.D., Lerner R.A., Benkovic S.J. Substituent effects on an antibody-catalyzed hydrolysis of phenyl-esters: further evidence for an acyl-antibody intermediate. J Am Chem Soc 1992, 114:3528-3534.
-
(1992)
J Am Chem Soc
, vol.114
, pp. 3528-3534
-
-
Gibbs, R.A.1
Benkovic, P.A.2
Janda, K.D.3
Lerner, R.A.4
Benkovic, S.J.5
-
31
-
-
0023759322
-
Induction of an antibody that catalyzes the hydrolysis of an amide bond
-
Janda K.D., Schloeder D., Benkovic S.J., Lerner R.A. Induction of an antibody that catalyzes the hydrolysis of an amide bond. Science 1988, 241:1188-1191.
-
(1988)
Science
, vol.241
, pp. 1188-1191
-
-
Janda, K.D.1
Schloeder, D.2
Benkovic, S.J.3
Lerner, R.A.4
-
32
-
-
0031587461
-
Catalysis of hydrolysis and transesterification reactions of p-nitrophenyl esters by a designed helix-loop-helix dimer
-
Broo K.S., Brive L., Ahlberg P., Baltzer L. Catalysis of hydrolysis and transesterification reactions of p-nitrophenyl esters by a designed helix-loop-helix dimer. J Am Chem Soc 1997, 119:11362-11372.
-
(1997)
J Am Chem Soc
, vol.119
, pp. 11362-11372
-
-
Broo, K.S.1
Brive, L.2
Ahlberg, P.3
Baltzer, L.4
-
33
-
-
0034674345
-
a of reactive esters sets the stage for cooperativity in nucleophilic and general-acid catalysis
-
a of reactive esters sets the stage for cooperativity in nucleophilic and general-acid catalysis. Chemistry 2000, 6:2214-2220.
-
(2000)
Chemistry
, vol.6
, pp. 2214-2220
-
-
Nilsson, J.1
Baltzer, L.2
-
34
-
-
0035807809
-
Enzyme-like proteins by computational design
-
Bolon D.N., Mayo S. Enzyme-like proteins by computational design. Proc Natl Acad Sci U S A 2001, 98:14274-14279.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 14274-14279
-
-
Bolon, D.N.1
Mayo, S.2
-
35
-
-
0842270116
-
Enzyme-like proteins from an unselected library of designed amino acid sequences
-
Wei Y., Hecht M.H. Enzyme-like proteins from an unselected library of designed amino acid sequences. Protein Eng Des Sel 2004, 17:67-75.
-
(2004)
Protein Eng Des Sel
, vol.17
, pp. 67-75
-
-
Wei, Y.1
Hecht, M.H.2
-
36
-
-
84867053249
-
Computational design of catalytic dyads and oxyanion holes for ester hydrolysis
-
Richter F., Blomberg R., Khare S.D., Kiss G., Kuzin A.P., Smith A.J.T., Gallaher J., Pianowski Z., Helgeson R.C., Grjasnow A., et al. Computational design of catalytic dyads and oxyanion holes for ester hydrolysis. J Am Chem Soc 2012, 134:16197-16206.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 16197-16206
-
-
Richter, F.1
Blomberg, R.2
Khare, S.D.3
Kiss, G.4
Kuzin, A.P.5
Smith, A.J.T.6
Gallaher, J.7
Pianowski, Z.8
Helgeson, R.C.9
Grjasnow, A.10
-
37
-
-
84896925534
-
Short peptides self-assemble to produce catalytic amyloids
-
Rufo C.M., Moroz Y.S., Moroz O.V., Stöhr J., DeGrado W.F., Korendovych I.V. Short peptides self-assemble to produce catalytic amyloids. Nat Chem 2014, 6:303-309.
-
(2014)
Nat Chem
, vol.6
, pp. 303-309
-
-
Rufo, C.M.1
Moroz, Y.S.2
Moroz, O.V.3
Stöhr, J.4
DeGrado, W.F.5
Korendovych, I.V.6
-
38
-
-
84860773275
-
Catalysis by a de novo zinc-mediated protein interface: implications for natural enzyme evolution and rational enzyme engineering
-
Der B.S., Edwards D.R., Kuhlman B. Catalysis by a de novo zinc-mediated protein interface: implications for natural enzyme evolution and rational enzyme engineering. Biochemistry 2012, 51:3933-3940.
-
(2012)
Biochemistry
, vol.51
, pp. 3933-3940
-
-
Der, B.S.1
Edwards, D.R.2
Kuhlman, B.3
-
39
-
-
84856397386
-
Hydrolytic catalysis and structural stabilization in a designed metalloprotein
-
Zastrow M.L., Peacock A.F.A., Stuckey J.A., Pecoraro V.L. Hydrolytic catalysis and structural stabilization in a designed metalloprotein. Nat Chem 2012, 4:118-123.
-
(2012)
Nat Chem
, vol.4
, pp. 118-123
-
-
Zastrow, M.L.1
Peacock, A.F.A.2
Stuckey, J.A.3
Pecoraro, V.L.4
-
40
-
-
84862776507
-
Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
-
Khare S.D., Kipnis Y., Greisen P., Takeuchi R., Ashani Y., Goldsmith M., Song Y., Gallaher J.L., Silman I., Leader H., et al. Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis. Nat Chem Biol 2012, 8:294-300.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 294-300
-
-
Khare, S.D.1
Kipnis, Y.2
Greisen, P.3
Takeuchi, R.4
Ashani, Y.5
Goldsmith, M.6
Song, Y.7
Gallaher, J.L.8
Silman, I.9
Leader, H.10
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