Concerted versus stepwise mechanism in thymidylate synthase

Journal of the American Chemical Society

Volumn 136, Issue 28, 2014, Pages 9850-9853

  Islam, Zahidul ^a   Strutzenberg, Timothy S ^a   Gurevic, Ilya ^a   Kohen, Amnon ^a  

^a E11 SSH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGY; CATALYSIS; ISOTOPES; REACTION INTERMEDIATES;

BIOMIMETIC CATALYSTS; CONCERTED MECHANISM; DNA BUILDING BLOCKS; ENOLATE INTERMEDIATES; KINETIC ISOTOPE EFFECTS; QM/MM CALCULATIONS; SUBSTRATE BINDING; THYMIDYLATE SYNTHASE;

HYDRIDES;

ARGININE; CYSTEINE; THYMIDYLATE SYNTHASE;

BIOMIMETICS; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; KINETICS; METABOLISM; MUTAGENESIS; PROTEIN CONFORMATION;

ARGININE; BIOMIMETICS; CATALYSIS; CYSTEINE; KINETICS; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN CONFORMATION; THYMIDYLATE SYNTHASE;

EID: 84904437959     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja504341g     Document Type: Article

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