Functional body composition and related aspects in research on obesity and cachexia: Report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany

Obesity Reviews

Volumn 15, Issue 8, 2014, Pages 640-656

  Muller M J ^a   Baracos, V ^b   Bosy Westphal, A ^c   Dulloo, A G ^d   Eckel, J ^e   Fearon, K C H ^f   Hall, K D ^g   Pietrobelli, A ^h   Sorensen T I A ⁱ   Speakman, J ^j,k   Trayhurn, P ^l   Visser, M ^m   Heymsfield, S B ⁿ  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF ALBERTA   (Canada)

^c UNIVERSITY OF HOHENHEIM   (Germany)

^d UNIVERSITY OF FRIBOURG   (Switzerland)

^e LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^f WESTERN GENERAL HOSPITAL   (United Kingdom)

^g NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^h UNIVERSITY OF VERONA   (Italy)

ⁱ UNIVERSITY OF COPENHAGEN   (Denmark)

^j INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^k UNIVERSITY OF ABERDEEN   (United Kingdom)

^l UNIVERSITY OF BUCKINGHAM   (United Kingdom)

^m VU UNIVERSITY MEDICAL CENTER   (Netherlands)

ⁿ PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

more..

Author keywords

Adipose tissue; Body composition; Metabolism; Muscle mass

Indexed keywords

ADIPOCYTOKINE;

ADIPOSE TISSUE; BODY COMPOSITION; BODY WEIGHT; CACHEXIA; CELL FUNCTION; CLINICAL RESEARCH; DISEASE COURSE; ENERGY EXPENDITURE; EXERCISE; FAT FREE MASS; FAT MASS; FEEDBACK SYSTEM; GERMANY; HUMAN; IN VIVO STUDY; INFLAMMATION; INTRAUTERINE GROWTH RETARDATION; MALNUTRITION; NONHUMAN; NUTRITION; OBESITY; REFEEDING; REVIEW; SKELETAL MUSCLE; WEIGHT CHANGE; WEIGHT CONTROL; WEIGHT GAIN; ANIMAL; BLOOD; DISEASE MODEL; ENERGY METABOLISM; METABOLISM; ORGANIZATION;

ADIPOKINES; ADIPOSE TISSUE; ANIMALS; BODY COMPOSITION; BODY WEIGHT; CACHEXIA; CONGRESSES AS TOPIC; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GERMANY; HUMANS; MUSCLE, SKELETAL; OBESITY;

EID: 84904433704     PISSN: 14677881     EISSN: 1467789X     Source Type: Journal    
DOI: 10.1111/obr.12187     Document Type: Review

References (130)

1. Shen W, St-Onge M-P, Wang Z, Heymsfield SB. Study of body composition: an overview. In: Heymsfield SB, Lohman TG, Wang Z, Going SB (eds). Human Body Composition, 2nd edn. Human Kinetics: Champaign, Il, 2005, pp. 3-14.
2. Müller MJ. From BMI to functional body composition. Eur J Clin Nutr 2013; 67: 1119-1121.
3. Ahima R, Lazar MA. Physiology. The health risk of obesity - better metrics imperative. Science 2013; 341: 856-858.
4. Benedict FG. A Study of Prolonged Fasting. Carnegie Institute: Washington DC, 1915. Publication 203.
5. Keys A, Brozek J, Henschel A, Mickelsen O, Taylor HL. The Biology of Human Starvation. The University of Minnesota Press: Minneapolis, London, 1950.
6. Dulloo AG, Jaquet J. The control of partitioning between protein and fat during human starvation: its internal determinants and biological significance. Br J Nutr 1999; 82: 339-356.
7. Forbes G. Lean body mass-body fat interrelationships in humans. Nutr Rev 1987; 45: 225-231.
8. Hall KG. Modeling metabolic adaptations and energy regulation in humans. Ann Rev Nutr 2012; 32: 35-44.
9. Müller MJ, Wang Z, Heymsfield SB, Schautz B, Bosy-Westphal A. Advances in the understanding of specific metabolic rates of major organs and tissues in humans. Curr Opin Clin Nutr Metab Care 2013; 16: 501-508.
10. Wikepedia. [WWW document]. http://en.wikipedia.org/wiki/Crosstalk_(electronics).(accessed September 2013)
11. Stock MJ. Obesity and cachexia: possibilities of an integrated approach. In: Rothwell NJ, Stock MJ (eds). Obesity and Cachexia. Physiological Mechanisms and New Approaches to Phasmacological Control. John Wiley & Sons: Chichester, 1991, pp. 1-12.
12. Müller MJ, Danforth E, Burger AG, Siedentopp U. Hormones and Nutrition in Obesity and Cachexia. Springer: Heidelberg, 1990.
13. Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med 1995; 332: 621-628.
14. Heilbronn LK, de Jonge L, Frisard MI, Pennington CALERIE Team etal. Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial. JAMA 2006; 295: 1539-1548.
15. Hall KD. Computational model of in vivo human energy metabolism during semistarvation and refeeding. Am J Physiol Endocrinol Metab 2006; 291: E23-E37.
16. Hall KD. Predicting metabolic adaptation, body weight change, and energy intake in humans. Am J Physiol Endocrinol Metab 2010; 298: E449-E466.
17. Hall KD, Sacks G, Chandramohan D etal. Quantification of the effect of energy imbalance on body weight. Lancet 2011; 378: 826-837.
18. Hall KD. Diet versus exercise in 'the biggest loser' weight loss competition. Obesity (Silver Spring) 2013; 21: 957-959.
19. Hallgreen CE, Hall KD. Allometric relationship between changes of visceral fat and total fat mass. Int J Obes 2008; 32: 845-852.
20. Lieffers JR, Mourtzakis M, Hall KD, McCargar LJ, Prado CM, Baracos VE. A viscerally driven cachexia syndrome in patients with advanced colorectal cancer: contributions of organ and tumor mass to whole-body energy demands. Am J Clin Nutr 2009; 89: 1173-1179.
21. Dulloo AG, Jacquet J, Montani JP, Schutz Y. Adaptive thermogenesis in human body weight regulation: more of a concept than a measurable entity. Obes Rev 2012; 13: 105-121.
22. Dulloo AG, Jacquet J, Montani JP. How dieting makes some fatter: from a perspective of human body composition autoregulation. Proc Nutr Soc 2012; 71: 379-389.
23. Dulloo AG, Jacquet J, Girardier L. Poststarvation hyperphagia and body fat overshooting in humans: a role for feedback signals from lean and fat tissues. Am J Clin Nutr 1997; 65: 717-723.
24. Dulloo AG, Jacquet J. Adaptive reduction in basal metabolic rate in response to food deprivation in humans: a role for feedback signals from fat stores. Am J Clin Nutr 1998; 68: 599-606.
25. Montani JP, Viecelli AK, Prévot A, Dulloo AG. Weight cycling during growth and beyond as a risk factor for later cardiovascular diseases: the 'repeated overshoot' theory. Int J Obes (Lond) 2006; 30(Suppl. 4): S58-S66.
26. Braun TP, Zhu X, Szumowski M etal. Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic-pituitary-adrenal axis. J Exp Med 2011; 208: 2449-2463.
27. Ravussin E, Bogardus C. Relationship of genetics, age, and physical fitness to daily energy expenditure and fuel utilization. Am J Clin Nutr 1989; 49(Suppl. ): 968-975.
28. Tschöp MH, Speakman JR, Arch JR etal. A guide to analysis of mouse energy metabolism. Nat Methods 2011; 9: 57-63.
29. Heymsfield SB, Thomas D, Bosy-Westphal A, Shen W, Peterson CM, Müller MJ. Evolving concepts on adjusting human resting energy expenditure measurements for body size. Obes Rev 2012; 13: 1001-1014.
30. Later W, Bosy-Westphal A, Kossel E, Glüer CC, Heller M, Müller MJ. Is the 1975 Reference Man still a suitable reference? Eur J Clin Nutr 2010; 64: 1035-1042.
31. Bosy-Westphal A, Braun W, Schautz B, Müller MJ. Issues in characterizing resting energy expenditure in obesity and after weight loss. Front Physiol 2013; 4(article 47): 1-9.
32. Müller MJ, Langemann D, Gehrke I etal. Effect of constitution on mass of individual organs and their association with metabolic rate in humans - a detailed view on allometric scaling. PLoS ONE 2011; 6: e22732.
33. Prado CM, Sawyer MB, Ghosh S etal. Central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential? Am J Clin Nutr 2013; 98: 1012-1019.
34. Rosenbaum M, Leibel RL. Adaptive thermogenesis in humans. Int J Obes (Lond) 2010; 34(Suppl. 1): S47-S55.
35. Müller MJ, Bosy-Westphal A. Adaptive thermogenesis with weight loss in humans. Obesity (Silver Spring) 2013; 21: 218-228.
36. Larsen TM, Dalskov SM, van Baak M, Diet, Obesity, and Genes (Diogenes) Project etal. Diets with high or low protein content and glycemic index for weight-loss maintenance. N Engl J Med 2010; 363: 2102-2113.
37. Rebelos E, Muscelli E, Natali A, RISC Study Investigators etal. Body weight, not insulin sensitivity or secretion, may predict spontaneous weight changes in nondiabetic and prediabetic subjects: the RISC study. Diabetes 2011; 60: 1938-1945.
38. Swinburn BA, Nyomba BL, Saad MF etal. Insulin resistance associated with lower rates of weight gain in Pima Indians. J Clin Invest 1991; 88: 168-173.
39. Wong MH, Holst C, Astrup A etal. Caloric restriction induces changes in insulin and body weight measurements that are inversely associated with subsequent weight regain. PLoS ONE 2012; 7: e42858.
40. Lagerpusch M, Enderle J, Later W etal. Impact of glycaemic index and dietary fibre on insulin sensitivity during the refeeding phase of a weight cycle in young healthy men. Br J Nutr 2013; 109: 1606-1616.
41. Lagerpusch M, Enderle J, Eggeling B etal. Carbohydrate quality and quantity affect glucose and lipid metabolism during weight regain in healthy men. J Nutr 2013; 143: 1593-1601.
42. Raschke S, Eckardt K, Bjørklund Holven K, Jensen J, Eckel J. Identification and validation of novel contraction-regulated myokines released from primary human skeletal muscle cells. PLoS ONE 2013; 8: e62008.
43. Hartwig S, Raschke S, Knebel B etal. Secretome profiling of primary human skeletal muscle cells. Biochim Biophys Acta 2014; 1844: 1011-1017.
44. Boström P, Wu J, Jedrychowski MP etal. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012; 481: 463-468.
45. Raschke S, Elsen M, Gassenhuber H etal. Evidence against a beneficial effect of Irisin in humans. PLoS ONE 2013; 8: e73680.
46. Raschke S, Eckel J. Adipo-myokines: two sides of the same coin - mediators of inflammation and mediators of exercise. Mediators Inflamm 2013; 2013: 320724.
47. Rajala MW, Scherer PE. The adipocyte - at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 2003; 144: 3765-3773.
48. Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004; 92: 347-355.
49. Trayhurn P. Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiol Scand 2005; 184: 285-293.
50. Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860-867.
51. Rosen ED, Spiegelman BM. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 2006; 444: 847-853.
52. Dahlman I, Elsen M, Tennagels N etal. Functional annotation of the human fat cell secretome. Archiv Physiol Biochemy 2012; 118: 84-91.
53. Hotamisligil GS. Inflammatory pathways and insulin action. Int J Obesity 2003; 27(Suppl. 3): S53-S55.
54. Zhang YY, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homolog. Nature 1994; 372: 425-432.
55. Arita Y, Kihara S, Ouchi N etal. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999; 257: 79-83.
56. Hotta K, Funahashi T, Arita Y etal. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscl Thromb Vasc Biol 2000; 20: 1595-1599.
57. Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nature Med 2001; 7: 947-953.
58. Ouchi N, Kihara S, Arita Y etal. Novel modulator for endothelial adhesion molecules - Adipocyte-derived plasma protein adiponectin. Circulation 1999; 100: 2473-2476.
59. Yamauchi T, Kamon J, Waki H etal. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nature Med 2001; 7: 941-946.
60. Trayhurn P. Hypoxia and adipose tissue function and dysfunction in obesity. Physiol Rev 2013; 93: 1-21.
61. Pedersen BK, Steensberg A, Keller P etal. Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects. Pflügers Archiv Eur J Physiol 2003; 446: 9-16.
62. Pedersen BK, Febbraio MA. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol 2012; 8: 457-465.
63. Haugen F, Norheim F, Lian H etal. IL-7 is expressed and secreted by human skeletal muscle cells. Am J Physiol Cell Physiol 2010; 298: C807-C816.
64. Pedersen BK, Febbraio MA. Muscle as an endocrine Organ: focus on muscle-derived Interleukin-6. Physiol Rev 2008; 88: 1379-1406.
65. Trayhurn P, Drevon CA, Eckel J. Secreted proteins from adipose tissue and skeletal muscle - adipokines, myokines and adipose/muscle cross-talk. Arch Physiol Biochem 2011; 117: 47-56.
66. Bortoluzzi S, Scannapieco P, Cestaro A, Danieli G, Schiaffino S. Computational reconstruction of the human skeletal muscle secretome. Proteins 2006; 62: 776-792.
67. Yoon J, Yea K, Kim J etal. Comparative proteomic analysis of the insulin-induced L6 myotube secretome. Proteomics 2009; 9: 51-60.
68. Henningsen J, Rigbolt K, Blagoev B, Pedersen B, Kratchmarova I. Dynamics of the skeletal muscle secretome during myoblast differentiation. Mol Cell Proteomics 2010; 9: 2482-2496.
69. Bostrom P, Wu J, Jedrychowski MP etal. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012; 481: 463-468.
70. Wu J, Boström P, Sparks Lauren M etal. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 2012; 150: 366-376.
71. Fearon K, Arends J, Baracos V. Understanding the mechanisms and treatment options in cancer cachexia. Nat Rev Clin Oncol. 2013; 10: 90-99.
72. Martin L, Birdsell L, Macdonald N etal. Cancer cachexia in the age of obesity: skeletal muscle depletion is a powerful prognostic factor, independent of body mass index. J Clin Oncol 2013; 31: 1539-1547.
73. Prado CM, Lieffers JR, McCargar LJ etal. Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study. Lancet Oncol 2008; 9: 629-635.
74. Lieffers JR, Bathe OF, Fassbender K, Winget M, Baracos VE. Sarcopenia is associated with postoperative infection and delayed recovery from colorectal cancer resection surgery. Br J Cancer 2012; 107: 931-936.
75. Parsons HA, Baracos VE, Dhillon N, Hong DS, Kurzrock R. Body composition, symptoms, and survival in advanced cancer patients referred to a phase I service. PLoS ONE 2012; 7: e29330.
76. Antoun S, Lanoy E, Iacovelli R etal. Skeletal muscle density predicts prognosis in patients with metastatic renal cell carcinoma treated with targeted therapies. Cancer 2013; 119: 3377-3384.
77. Bing C, Trayhurn P. New insights into adipose tissue atrophy in cancer cachexia. Proc Nutr Soc 2009; 68: 385-392.
78. Stephens NA, Skipworth RJ, Macdonald AJ, Greig CA, Ross JA, Fearon KC. Intramyocellular lipid droplets increase with progression of cachexia in cancer patients. J Cachexia Sarcopenia Muscle 2011; 2: 111-117.
79. Fearon KC. Cancer cachexia and fat-muscle physiology. N Engl J Med 2011; 365: 565-567.
80. Johns N, Stephens NA, Fearon KC. Muscle wasting in cancer. Int J Biochem Cell Biol 2013; 45: 2215-2229.
81. Gallagher IJ, Stephens NA, MacDonald AJ etal. Suppression of skeletal muscle turnover in cancer cachexia: evidence from the transcriptome in sequential human muscle biopsies. Clin Cancer Res 2012; 18: 2817-2827.
82. Bing C, Bao Y, Jenkins J etal. Zinc-α2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia. PNAS 2004; 101: 2500-2505.
83. Mracek T, Stephens NA, Gao D etal. Enhanced ZAG production by subcutaneous adipose tissue is linked to weight loss in gastrointestinal cancer patients. Br J Cancer 2011; 104: 441-447.
84. Sørensen TIA. Is obesity a healthy active response to an expected future lack of energy rather than a passive storage of surplus energy. Obes Facts 2012; 5: 431-435.
85. Sørensen TIA. Obesity defined as Excess Storage of inert Triglycerides - do we need a paradigm shift? Obes Facts 2011; 4: 91-94.
86. Li X, Cope BM, Johnson MS, Smith DL, Nagy TR. Mild calorie restriction reduces fat accumulation in female C57BL/6J mice. Obesity 2010; 18: 456-462.
87. Spalding KL, Arner E, Westermark PO etal. Dynamics of fat cell turnover in humans. Nature 2008; 453: 783-787.
88. Zimmermann E, Holst C, Sörensen TIA. Lifelong doubling of mortality in men entering adult life as obese. Int J Obes 2011; 35: 1193-1199.
89. Barker DJP. Mothers, Babies and Health in Later Life, 1st edn. Churchill Livingstone: London, UK, 1998.
90. Godfrey KM, Barker DJP. Fetal programming and adult health. Public Health Nutr 2001; 4: 611-624.
91. Canani RB, Costanzo MD, Leone L etal. Epigenetic mechanisms elicited by nutrition in early life. Nutr Res Rev 2011; 24: 198-205.
92. Cianfarani S, Agostoni C, Bedogni G etal. Effect of intrauterine growth retardation on liver and long-term metabolic risk. Int J Obes (Lond) 2012; 36: 1270-1277.
93. Mori M, Mori H, Yamori Y, Tsuda K. Low birth weight as cardiometabolic risk in Japanese high school girls. J Am Coll Nutr 2012; 31: 39-44.
94. Johnson RC, Schoeni RF. Early-life origins of adult disease: national longitudinal population-based study of the United States. Am J Public Health 2011; 101: 2317-2324.
95. Zampieri N, Pietrobelli A, Biban P, Soffiati M, Dall'agnola A, Camoglio FS. Lactobacillus paracasei subsp. paracasei F19 in Bell's stage 2 of necrotizing enterocolitis. Minerva Pediatr 2013; 65: 353-360.
96. Hack M, Schluchter M, Andreias L etal. Change in prevalence of chronic conditions between childhood and adolescence among extremely low-birth-weight children. JAMA 2011; 306: 394-401.
97. Faith MS, Heshka S, Keller KL etal. Maternal-child feeding patterns and child body weight: findings from a population-based sample. Arch Pediatr Adolesc Med 2003; 157: 926-932.
98. Fomon SJ, Haschke F, Ziegler EE, Nelson SE. Body composition of reference children from birth to age 10 years. Am J Clin Nutr 1982; 35(5 Suppl. ): 1169-1175.
99. Cole TJ, Faith MS, Pietrobelli A, Heo M. What is the best measure of adiposity change in growing children: BMI, BMI %, BMI z-score or BMI centile? Eur J Clin Nutr 2005; 59: 419-425.
100. Wells JCK. The Evolutionary Biology of Human Body Fatness. Thrift and control. Cambridge University Press: Cambridge, 2010.
101. Rudolf M. Predicting babies' risk of obesity. Arch Dis Child 2011; 96: 995-997.
102. Drøyvold WB, Nilsen TI, Krüger O etal. Change in height, weight and body mass index: longitudinal data from the HUNT Study in Norway. Int J Obes 2006; 30: 935-939.
103. Drøyvold WB, Lund Nilsen TI, Lydersen S etal. Weight change and mortality: the Nord-Trøndelag health study. J Intern Med 2005; 257: 338-345.
104. Ding J, Kritchevsky SB, Newman AB etal. Health ABC Study. Effects of birth cohort and age on body composition in a sample of community-based elderly. Am J Clin Nutr 2007; 85: 405-410.
105. Song MY, Ruts E, Kim J, Janumala I, Heymsfield S, Gallagher D. Sarcopenia and increased adipose tissue infiltration of muscle in elderly African American women. Am J Clin Nutr 2004; 79: 874-880.
106. Lang T, Cauley JA, Tylavsky F etal. Computed tomographic measurements of thigh muscle cross-sectional area and attenuation coefficient predict hip fracture: the health, aging, and body composition study. J Bone Miner Res 2010; 25: 513-519.
107. Schwartz AV, Sigurdsson S, Hue TF etal. Vertebral bone marrow fat associated with lower trabecular BMD and prevalent vertebral fracture in older adults. J Clin Endocrinol Metab 2013; 98: 2294-2300.
108. Frontera WR, Reid KF, Phillips EM etal. Muscle fiber size and function in elderly humans: a longitudinal study. J Appl Physiol 2008; 105: 637-642.
109. Delmonico MJ, Harris TB, Visser M Health, Aging, and Body etal. Longitudinal study of muscle strength, quality, and adipose tissue infiltration. Am J Clin Nutr 2009; 90: 1579-1585.
110. Kugel H, Jung C, Schulte O, Heindel W. Age- and sex-specific differences in the 1H-spectrum of vertebral bone marrow. J Magn Reson Imaging 2001; 13: 263-268.
111. Goodpaster BH, Park SW, Harris TB etal. The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci 2006; 61: 1059-1064.
112. Taaffe DR, Cauley JA, Danielson M etal. Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the health, aging, and body composition study. J Bone Miner Res 2001; 16: 1343-1352.
113. De Laet C, Kanis JA, Odén A etal. Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int 2005; 16: 1330-1338.
114. Langlois JA, Visser M, Davidovic LS, Maggi S, Li G, Harris TB. Hip fracture risk in older white men is associated with change in body weight from age 50 years to old age. Arch Intern Med 1998; 158: 990-996.
115. Armstrong ME, Cairns BJ, Banks E, Million Women Study Collaborators etal. Different effects of age, adiposity and physical activity on the risk of ankle, wrist and hip fractures in postmenopausal women. Bone 2012; 50: 1394-1400.
116. Compston JE, Flahive J, Hosmer DW GLOW Investigators etal. Relationship of weight, height, and body mass index with fracture risk at different sites in postmenopausal women: the global longitudinal study of osteoporosis in women (GLOW). J Bone Miner Res 2014; 29: 487-493.
117. Griffith JF, Yeung DK, Antonio GE etal. Vertebral bone mineral density, marrow perfusion, and fat content in healthy men and men with osteoporosis: dynamic contrast-enhanced MR imaging and MR spectroscopy. Radiology 2005; 236: 945-951.
118. Walsh MC, Hunter GR, Livingstone MB. Sarcopenia in premenopausal and postmenopausal women with osteopenia, osteoporosis and normal bone mineral density. Osteoporos Int 2006; 17: 61-67.
119. DiGirolamo DJ, Kiel DP, Esser KA. Bone and skeletal muscle: neighbors with close ties. J Bone Miner Res 2013; 28: 1509-1518.
120. Kohrt WM, Barry DW, Schwartz RS. Muscle forces or gravity: what predominates mechanical loading on bone? Med Sci Sports Exerc 2009; 41: 2050-2055.
121. Perrini S, Laviola L, Carreira MC, Cignarelli A, Natalicchio A, Giorgino F. The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis. J Endocrinol 2010; 205: 201-210.
122. Szulc P, Beck TJ, Marchand F, Delmas PD. Low skeletal muscle mass is associated with poor structural parameters of bone and impaired balance in elderly men - the MINOS study. J Bone Miner Res 2005; 20: 721-729.
123. Elkasrawy MN, Hamrick MW. Myostatin (GDF-8) as a key factor linking muscle mass and bone structure. J Musculoskelet Neuronal Interact 2010; 10: 56-63.
124. Sjöblom S, Suuronen J, Rikkonen T, Honkanen R, Kröger H, Sirola J. Relationship between postmenopausal osteoporosis and the components of clinical sarcopenia. Maturitas 2013; 75: 175-180.
125. Johannesdottir F, Aspelund T, Siggeirsdottir K etal. Mid-thigh cortical bone structural parameters, muscle mass and strength, and association with lower limb fractures in older men and women (AGES-Reykjavik Study). Calcif Tissue Int 2012; 90: 354-364.
126. Schaap LA, Koster A, Visser M. Adiposity, muscle mass, and muscle strength in relation to functional decline in older persons. Epidemiol Rev 2013; 35: 51-65.
127. Baracos V, Caserotti P, Earthman CP etal. Advances in the science and application of body composition measurement. J Parenter Enteral Nutr 2012; 36: 96-107.
128. Müller MJ, Bosy-Westphal A, Lagerpusch M, Heymsfield SB. Use of balance methods for assessment of short-term changes in body composition. Obesity (Silver Spring) 2012; 20: 701-707.
129. Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002; 51: 2944-2950.
130. Yokota T, Oritani K, Takahashi I etal. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000; 96: 1723-1732.