Induction of galectin-1 by TGF-β1 accelerates fibrosis through enhancing nuclear retention of Smad2

Experimental Cell Research

Volumn 326, Issue 1, 2014, Pages 125-135

  Jin Lim, Min ^a   Ahn, Jiyeon ^a   Youn Yi, Jae ^a   Kim, Mi Hyoung ^a   Son, A Rang ^a   Lee, Sae lo oom ^a   Lim, Dae Seog ^b   Soo Kim, Sung ^c   Ae Kang, Mi ^a   Han, Youngsoo ^d   Song, Jie Young ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b CHA University   (South Korea)

^c Kyung Hee University Hospital   (South Korea)

^d Sookmyung Women's University   (South Korea)

Author keywords

Bleomycin; Fibrosis; Galectin 1; Smad 2; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; COLLAGEN TYPE 1; FIBRONECTIN; GALECTIN 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG FIBROSIS; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; UPREGULATION; WESTERN BLOTTING;

BLEOMYCIN; FIBROSIS; GALECTIN-1; SMAD-2; TGF-Β;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; GALECTIN 1; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; MICE; PHOSPHORYLATION; PULMONARY FIBROSIS; RNA, SMALL INTERFERING; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84904392467     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.06.001     Document Type: Article

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