N-myc-dependent repression of Ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant

Mechanisms of Development

Volumn 83, Issue 1-2, 1999, Pages 39-52

  Shimono, Akihiko ^a   Okuda, Tomohiko ^a   Kondoh, Hisato ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

cDNA subtraction; Downstream genes; L5; N myc mutant embryos; Ndr1

Indexed keywords

COMPLEMENTARY DNA; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; LIMB DEVELOPMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C MYB; PRIORITY JOURNAL; PROMOTER REGION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; EMBRYO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MICE; MICE, INBRED ICR; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEAR PROTEINS; PLANT PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; TRANSCRIPTION FACTORS; UP-REGULATION;

ANIMALIA; RODENTIA; VERTEBRATA;

EID: 0033006387     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(99)00025-8     Document Type: Article

References (47)

1. Alex R., Sozeri O., Meyer S., Dildrop R. Determination of the DNA sequence recognized by the bHLH-zip domain of the N-myc protein. Nucl. Acids Res. 9:1992;2257-2263.
2. Bella-Fernandez C., Packham G., Cleveland J.L. The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proc. Natl. Acad. Sci. USA. 90:1993;7804-7808.
3. Benvenisty N., Leder A., Kuo A., Leder P. An embryonically expressed gene is a target for c-Myc regulation via the c-Myc-binding sequence. Genes Dev. 6:1992;2513-2523.
4. Blackwell T.K., Kretzner L., Blackwood E.M., Eisenman R.N., Weintraub H. Sequence-specific DNA binding by the c-Myc protein. Science. 250:1990;1149-1151.
5. Blackwood M.E., Eisenman N.R. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science. 251:1991;1211-1217.
6. Charron J., Malynn A.B., Fisher P., Stewart V., Jeannotte L., Goff P.S., Robertson J.E., Alt W.F. Embryonic lethality in mice homozygous for targeted disruption of the N-myc gene. Genes Dev. 6:1992;2248-2257.
7. Downs M.K., Martin R.G., Bishop M.J. Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo. Genes Dev. 3:1989;860-869.
8. Eilers M., Schirm S., Bishop J.M. The MYC protein activates transcription of the α-prothymosin gene. EMBO J. 10:1991;133-141.
9. Facchini L.M., Chen S., Marhin W.W., Laer J.N., Penn L.Z. The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc minimal promoter. Mol. Cell. Biol. 17:1997;100-114.
10. Facchini L.M., Penn L.Z. The molecular role of Myc in growth and transformation: recent discoveries lead to new insights. Fed Am Soc Exp Biol J. 12:1998;633-651.
11. Frohman M.A., Dush M.K., Martin G.R. Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA. 85:1988;8998-9002.
12. Galaktionov K., Chen X., Beach D. Cdc25 cell-cycle phosphatase as a target of c-myc. Nature. 382:1996;511-517.
13. Grandori C., Mac J., Siebelt F., Ayer D.B., Bisenman R.N. Myc-Max heterodimers activate a DEAD box gene and interact with multiple E-box-related sites in vivo. EMBO J. 15:1996;4344-4357.
14. Hirning U., Schmid P., Schulz A.W., Rettenberger G., Hameister H. A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis. Mech. Dev. 33:1991;119-126.
15. Kamachi Y., Kondoh H. Overlapping positive and negative regulatory elements determine lens-specific activity of the δ1-crystallin gene. Mol. Cell. Biol. 13:1993;5206-5215.
16. Kanamori A., Brown D.D. Cultured cells as a model for amphibian metamorphosis. Proc. Natl. Acad. Sci. USA. 90:1993;6013-6017.
17. Kato K., Kanamori K., Kondoh H. Rapid and transient decrease of N-myc expression in retinoic acid-induced differentiation of OTF9 teratocarcinoma stem cells. Mol. Cell. Biol. 10:1990;486-491.
18. Kato K., Kanamori K., Wakamatsu Y., Sawai S., Kondoh H. Tissue distribution of N-myc expression in the early organogenesis period of the mouse embryo. Dev. Growth Differ. 33:1991;29-36.
19. Kokame K., Kato H., Miyata T. Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. J. Biol. Chem. 271:1996;29659-29665.
20. Kräuter-Canham R., Bronner R., Bvrard J.-L., Hahne G., Freidt W., Steinmetz A. A transmiting tissue- and pollen-expressed protein from sunflower with sequence similarity to the human RTP protein. Plant Sci. 129:1997;191-202.
21. Lee L.A., Dolde C., Barrett J., Wu C.S., Dang C.V. A link between c-myc-mediated transcriptional repression and neoplastic transformation. J. Clin. Invest. 97:1996;1687-1695.
22. Li L.H., Nerlov C., Prendergast G., MacGregor D., Ziff B.B. c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO J. 13:1994;4070-4079.
23. Lin T.-M., Chang C. Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone. Proc. Natl. Acad. Sci. USA. 94:1997;4988-4993.
24. Mai S., Martensson I.L. The c-myc protein represses the lambda 5 and Tdt initiators. Nucl. Acids Res. 23:1995;1-9.
25. Marechal V., Blenbaas B., Piette J., Nicolas J., Levine A. The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes. Mol. Cell. Biol. 14:1994;7414-7420.
26. Moens C.B., Auerbach B.A., Conlon A.R., Joyner L.A., Rossant J. A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung. Genes Dev. 6:1992;691-704.
27. Moens C.B., Stanton B.R., Parada L.F., Rossant J. Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus. Development. 119:1993;485-499.
28. Momand J., Zambetti G.P., Olson D.C., George D., Levine A.J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53 mediated transactivation. Cell. 69:1992;1237-1245.
29. Mugrauer G., Alt F.W., Ekblom P. N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization. J. Cell. Biol. 107:1988;1325-1335.
30. Mugrauer G., Ekblom P. Contrasting expression patterns of three members of the myc family of protooncogenes in the developing and adult mouse kidney. J. Cell Biol. 112:1991;13-25.
31. Sawai S., Kato K., Wakamatsu Y., Kondoh H. Organization and expression of the chicken N-myc gene. Mol. Cell. Biol. 10:1990;2017-2026.
32. Sawai S., Shimono A., Hanaoka K., Kondoh H. Embryonic lethality resulting from disruption of both N-myc alleles in mouse zygotes. New Biol. 3:1991;861-869.
33. Sawai S., Shimono A., Wakamatsu Y., Palmes C., Hanaoka K., Kondoh H. Defects of embryonic organogenesis resulting from targeted disruption f N-myc gene in mouse. Development. 117:1993;1445-1455.
34. Shimono A., Kitamura A., Hanaoka K., Kondoh H. Requirement of N-myc protein down-regulation for neuronal differentiation in the spinal cord. Dev. Growth Differ. 38:1996;707-716.
35. Stanton R.B., Perkins S.A., Tessarollo L., Sassoon A.D., Parada F.L. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes Dev. 6:1992;2235-2247.
36. Struhl K. Histone acetylation and transcriptional regulatory mechanisms. Genes. Dev. 12:1998;599-606.
37. Tsuneoka M., Nakano F., Ohgusu H., Mekada B. c-myc activates RCC1 gene expression through E-box elements. Oncogene. 14:1997;2301-2311.
38. Uwanogho D., Rex M., Cartwright E., Pearl G., Scotting P.J., Sharpe P.T. Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggest an interactive role in neuronal development. Mech. Dev. 49:1995;23-36.
39. van Belzen N., Dinjens W.N.M., Diesveld M.P.G., Groen N.A., van der Made A.C.J., Nozawa Y., Vliestra R., Trapman J., Bosman F.T. A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms. Lab. Invest. 77:1997;85-92.
40. Wakamatsu Y., Watanabe Y., Shimono A., Kondoh H. Transition of localization of the N-myc protein from nucleus to cytoplasm in differentiating neurons. Neuron. 10:1993;1-20.
41. Wakamatsu Y., Watanabe Y., Nakamura H., Kondoh H. Regulation of neural crest cell fate by N-myc: promotion of ventral migration and neuronal differentiation. Development. 124:1997;1953-1962.
42. Wang Z., Brown D.D. A gene expression screen. Proc. Natl. Acad. Sci. USA. 88:1991;11505-11509.
43. Wenzel A., Cziepluch C., Hammann U., Schumann J., Schwab M. The N-myc oncoprotein is associated in vivo with the phosphoprotein Max (p20/22) in human neuroblastoma cell. EMBO J. 10:1991;3703-3712.
44. Wilkinson, D.G., 1992. Whole mount in situ hybridization of vertebrate embryos. In: Wilkinson., D.G. (Ed.), In situ Hybridization: a Practical Approach, IRL Press, Oxford, pp. 75-83.
45. Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T., Cooper J.et al. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature. 368:1994;32-38.
46. Yoshida M., Kojima K., Beppu T. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by Trichostatin A. J. Biol. Chem. 265:1990;17174-17179.
47. 2+ compounds. Cancer Res. 58:1998;2182-2189.