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Volumn 20, Issue , 2014, Pages 1188-1200

Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: Etiological contribution to complex regional pain syndromes (part II)

Author keywords

Chronic pain; Complex regional pain syndromes; Epigenomics; Ganglia, Spinal; Peripheral nerve injuries

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP; CYCLIC GMP; G PROTEIN COUPLED RECEPTOR KINASE 2; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID; NEUROKININ 1 RECEPTOR; NOTCH RECEPTOR; NUCLEAR TRANSCRIPTION FACTOR; OXYTOCIN; PROSTAGLANDIN E2; PROTEIN KINASE; PURINERGIC P2X3 RECEPTOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT PROTEIN; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; G PROTEIN COUPLED RECEPTOR;

EID: 84904328521     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: 10.12659/msm.890707     Document Type: Article
Times cited : (24)

References (94)
  • 2
    • 84903165086 scopus 로고    scopus 로고
    • Epigenetic modifcation of drg neuronal gene expression subsequent to nerve injury: Etiological contribution to complex regional pain syndromes (Part I)
    • Wang F, Stefano GB, Kream RM: Epigenetic modifcation of drg neuronal gene expression subsequent to nerve injury: Etiological contribution to complex regional pain syndromes (Part I). Med Sci Monit, 2014; 22: 1067-77
    • (2014) Med Sci Monit , vol.22 , pp. 1067-1077
    • Wang, F.1    Stefano, G.B.2    Kream, R.M.3
  • 3
    • 0033560123 scopus 로고    scopus 로고
    • Role of protein kinase A in the maintenance of infammatory pain
    • Aley KO, Levine JD: Role of protein kinase A in the maintenance of infammatory pain. J Neurosci, 1999; 19: 2181-86
    • (1999) J Neurosci , vol.19 , pp. 2181-2186
    • Aley, K.O.1    Levine, J.D.2
  • 4
    • 79958126295 scopus 로고    scopus 로고
    • Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats
    • Tumati S, Roeske WR, Largent-Milnes TM et al: Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats. J Neurosci Methods, 2011; 199: 62-68
    • (2011) J Neurosci Methods , vol.199 , pp. 62-68
    • Tumati, S.1    Roeske, W.R.2    Largent-Milnes, T.M.3
  • 5
    • 50249119619 scopus 로고    scopus 로고
    • A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1
    • Jeske NA, Diogenes A, Ruparel NB et al: A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1. Pain, 2008; 138: 604-16
    • (2008) Pain , vol.138 , pp. 604-616
    • Jeske, N.A.1    Diogenes, A.2    Ruparel, N.B.3
  • 6
    • 84855165622 scopus 로고    scopus 로고
    • Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons
    • Ritter DM, Ho C, O'Leary ME, Covarrubias M: Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons. J Physiol, 2012; 590: 145-61
    • (2012) J Physiol , vol.590 , pp. 145-161
    • Ritter, D.M.1    Ho, C.2    O'Leary, M.E.3    Covarrubias, M.4
  • 7
    • 77952524184 scopus 로고    scopus 로고
    • Regulation of the spontaneous augmentation of Na(V)1.9 in mouse dorsal root ganglion neurons: Efect of PKA and PKC pathways
    • Kakimura J, Zheng T, Uryu N, Ogata N: Regulation of the spontaneous augmentation of Na(V)1.9 in mouse dorsal root ganglion neurons: efect of PKA and PKC pathways. Mar Drugs, 2010; 8: 728-40
    • (2010) Mar Drugs , vol.8 , pp. 728-740
    • Kakimura, J.1    Zheng, T.2    Uryu, N.3    Ogata, N.4
  • 8
    • 68349111767 scopus 로고    scopus 로고
    • PKCepsilon-dependent potentiation of TTX-resistant Nav1.8 current by neurokinin-1 receptor activation in rat dorsal root ganglion neurons
    • Cang CL, Zhang H, Zhang YQ, Zhao ZQ: PKCepsilon-dependent potentiation of TTX-resistant Nav1.8 current by neurokinin-1 receptor activation in rat dorsal root ganglion neurons. Mol Pain, 2009; 5: 33
    • (2009) Mol Pain , vol.5 , pp. 33
    • Cang, C.L.1    Zhang, H.2    Zhang, Y.Q.3    Zhao, Z.Q.4
  • 9
    • 84907423612 scopus 로고    scopus 로고
    • Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute dissociation of dorsal root ganglion in rats
    • Huang ZJ, Li HC, Liu S, Song XJ: Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute dissociation of dorsal root ganglion in rats. Sheng Li Xue Bao, 2012; 64: 563-76
    • (2012) Sheng Li Xue Bao , vol.64 , pp. 563-576
    • Huang, Z.J.1    Li, H.C.2    Liu, S.3    Song, X.J.4
  • 10
    • 84865642980 scopus 로고    scopus 로고
    • Transient decrease in nociceptor GRK2 expression produces long-term enhancement in infammatory pain
    • Ferrari LF, Bogen O, Alessandri-Haber N et al: Transient decrease in nociceptor GRK2 expression produces long-term enhancement in infammatory pain. Neuroscience, 2012; 222: 392-403
    • (2012) Neuroscience , vol.222 , pp. 392-403
    • Ferrari, L.F.1    Bogen, O.2    Alessandri-Haber, N.3
  • 11
    • 77957193666 scopus 로고    scopus 로고
    • Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/ Rap1, protein kinase Cepsilon, and MEK/ERK
    • Eijkelkamp N, Wang H, Garza-Carbajal A et al: Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/ Rap1, protein kinase Cepsilon, and MEK/ERK. J Neurosci, 2010; 30: 12806-15
    • (2010) J Neurosci , vol.30 , pp. 12806-12815
    • Eijkelkamp, N.1    Wang, H.2    Garza-Carbajal, A.3
  • 12
    • 66449109997 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II after peripheral nerve injury
    • 2+/calmodulin-dependent protein kinase II after peripheral nerve injury. Mol Pain, 2009; 5: 22
    • (2009) Mol Pain , vol.5 , pp. 22
    • Hasegawa, S.1    Kohro, Y.2    Tsuda, M.3    Inoue, K.4
  • 13
    • 84865228570 scopus 로고    scopus 로고
    • 2+ currents in rat primary afferent neurons: Role of CaMKII and the effect of injury
    • 2+ currents in rat primary afferent neurons: role of CaMKII and the effect of injury. J Neurosci, 2012; 32: 11737-11749
    • (2012) J Neurosci , vol.32 , pp. 11737-11749
    • Tang, Q.1    Bangaru, M.L.2    Kostic, S.3
  • 14
    • 84858150429 scopus 로고    scopus 로고
    • Prostaglandin E2 contributes to the synthesis of brain-derived neurotrophic factor in primary sensory neuron in ganglion explant cultures and in a neuropathic pain model
    • Cruz Duarte P, St-Jacques B, Ma W: Prostaglandin E2 contributes to the synthesis of brain-derived neurotrophic factor in primary sensory neuron in ganglion explant cultures and in a neuropathic pain model. Exp Neurol, 2012; 234: 466-81
    • (2012) Exp Neurol , vol.234 , pp. 466-481
    • Cruz Duarte, P.1    St-Jacques, B.2    Ma, W.3
  • 15
    • 79851498855 scopus 로고    scopus 로고
    • Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway
    • Calvo M, Zhu N, Grist J, Ma Z et al: Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway. Glia, 2011; 59: 554-68
    • (2011) Glia , vol.59 , pp. 554-568
    • Calvo, M.1    Zhu, N.2    Grist, J.3    Ma, Z.4
  • 16
    • 74549130005 scopus 로고    scopus 로고
    • C-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?
    • Gao YJ, Ji RR: c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury? Open Pain J, 2009; 2: 11-17
    • (2009) Open Pain J , vol.2 , pp. 11-17
    • Gao, Y.J.1    Ji, R.R.2
  • 17
    • 0036711470 scopus 로고    scopus 로고
    • Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus
    • Ma W, Quirion R: Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus. Pain, 2002; 99: 175-84
    • (2002) Pain , vol.99 , pp. 175-184
    • Ma, W.1    Quirion, R.2
  • 18
    • 80052730373 scopus 로고    scopus 로고
    • Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain
    • Wang W, Mei XP, Wei YY et al: Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain. Brain Behav Immun, 2011; 25: 1355-66
    • (2011) Brain Behav Immun , vol.25 , pp. 1355-1366
    • Wang, W.1    Mei, X.P.2    Wei, Y.Y.3
  • 19
    • 84861210608 scopus 로고    scopus 로고
    • Role of JNK isoforms in the development of neuropathic pain following sciatic nerve transection in the mouse
    • Manassero G, Repetto IE, Cobianchi S et al: Role of JNK isoforms in the development of neuropathic pain following sciatic nerve transection in the mouse. Mol Pain, 2012; 8: 39
    • (2012) Mol Pain , vol.8 , pp. 39
    • Manassero, G.1    Repetto, I.E.2    Cobianchi, S.3
  • 20
    • 84861344458 scopus 로고    scopus 로고
    • The inhibition of the nitric oxide-cGMP-PKGJNK signaling pathway avoids the development of tolerance to the local antiallodynic efects produced by morphine during neuropathic pain
    • Hervera A, Leánez S, Pol O: The inhibition of the nitric oxide-cGMP-PKGJNK signaling pathway avoids the development of tolerance to the local antiallodynic efects produced by morphine during neuropathic pain. Eur J Pharmacol, 2012; 685: 42-51
    • (2012) Eur J Pharmacol , vol.685 , pp. 42-51
    • Hervera, A.1    Leánez, S.2    Pol, O.3
  • 21
    • 84885856314 scopus 로고    scopus 로고
    • A small molecule angiotensin ii type 2 receptor antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia
    • Smith MT, Woodruf TM, Wyse BD et al: A small molecule angiotensin ii type 2 receptor antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. Pain Med, 2013; 14: 1557-68
    • (2013) Pain Med , vol.14 , pp. 1557-1568
    • Smith, M.T.1    Woodruf, T.M.2    Wyse, B.D.3
  • 22
    • 84862179426 scopus 로고    scopus 로고
    • Mitogen activated protein kinase phosphatase-1 prevents the development of tactile sensitivity in a rodent model of neuropathic pain
    • Ndong C, Landry RP, DeLeo JA, Romero-Sandoval EA: Mitogen activated protein kinase phosphatase-1 prevents the development of tactile sensitivity in a rodent model of neuropathic pain. Mol Pain, 2012; 8: 34
    • (2012) Mol Pain , vol.8 , pp. 34
    • Ndong, C.1    Landry, R.P.2    Deleo, J.A.3    Romero-Sandoval, E.A.4
  • 23
    • 80053219483 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor activates cyclooxygenase 2-prostaglandin E2 in cultured spinal microglia
    • Wang F, Wu H, Xu S et al: Macrophage migration inhibitory factor activates cyclooxygenase 2-prostaglandin E2 in cultured spinal microglia. Neurosci Res, 2011; 71: 210-18
    • (2011) Neurosci Res , vol.71 , pp. 210-218
    • Wang, F.1    Wu, H.2    Xu, S.3
  • 24
    • 63849192564 scopus 로고    scopus 로고
    • P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation
    • Trang T, Beggs S, Wan X, Salter MW: P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation. J Neurosci, 2009; 29: 3518-28
    • (2009) J Neurosci , vol.29 , pp. 3518-3528
    • Trang, T.1    Beggs, S.2    Wan, X.3    Salter, M.W.4
  • 25
    • 66049094709 scopus 로고    scopus 로고
    • The c-kit signaling pathway is involved in the development of persistent pain
    • Sun YG, Gracias NG, Drobish JK et al: The c-kit signaling pathway is involved in the development of persistent pain. Pain, 2009; 144: 178-86
    • (2009) Pain , vol.144 , pp. 178-186
    • Sun, Y.G.1    Gracias, N.G.2    Drobish, J.K.3
  • 26
    • 84873146508 scopus 로고    scopus 로고
    • G-protein-coupled receptors: From structural insights to functional mechanisms
    • Chini B, Parenti M, Poyner DR, Wheatley M: G-protein-coupled receptors: from structural insights to functional mechanisms. Biochem Soc Trans, 2013; 41: 135-36
    • (2013) Biochem Soc Trans , vol.41 , pp. 135-136
    • Chini, B.1    Parenti, M.2    Poyner, D.R.3    Wheatley, M.4
  • 27
    • 84877145263 scopus 로고    scopus 로고
    • WNT signaling underlies the pathogenesis of neuropathic pain in rodents
    • Zhang YK, Huang ZJ, Liu S et al: WNT signaling underlies the pathogenesis of neuropathic pain in rodents. J Clin Invest, 2013; 123: 2268-86
    • (2013) J Clin Invest , vol.123 , pp. 2268-2286
    • Zhang, Y.K.1    Huang, Z.J.2    Liu, S.3
  • 28
    • 84856242233 scopus 로고    scopus 로고
    • Notch signaling inhibits axon regeneration
    • El Bejjani R, Hammarlund M: Notch signaling inhibits axon regeneration. Neuron, 2012; 73: 268-78
    • (2012) Neuron , vol.73 , pp. 268-278
    • El Bejjani, R.1    Hammarlund, M.2
  • 29
    • 54349096878 scopus 로고    scopus 로고
    • Neuroprotective efect of sonic hedgehog up-regulated in Schwann cells following sciatic nerve injury
    • Hashimoto M, Ishii K, Nakamura Y et al: Neuroprotective efect of sonic hedgehog up-regulated in Schwann cells following sciatic nerve injury. J Neurochem, 2008; 107: 918-27
    • (2008) J Neurochem , vol.107 , pp. 918-927
    • Hashimoto, M.1    Ishii, K.2    Nakamura, Y.3
  • 30
    • 84857722749 scopus 로고    scopus 로고
    • Protein kinase A activity and Hedgehog signaling pathway
    • Kotani T: Protein kinase A activity and Hedgehog signaling pathway. Vitam Horm, 2012; 88: 273-91
    • (2012) Vitam Horm , vol.88 , pp. 273-291
    • Kotani, T.1
  • 31
    • 80053331930 scopus 로고    scopus 로고
    • Hedgehog signaling regulates nociceptive sensitization
    • Babcock DT, Shi S, Jo J et al: Hedgehog signaling regulates nociceptive sensitization. Curr Biol, 2011; 21: 1525-33
    • (2011) Curr Biol , vol.21 , pp. 1525-1533
    • Babcock, D.T.1    Shi, S.2    Jo, J.3
  • 32
    • 84862809497 scopus 로고    scopus 로고
    • Small interfering RNA-mediated knockdown of NF-kBp65 attenuates neuropathic pain following peripheral nerve injury in rats
    • Sun T, Luo J, Jia M et al: Small interfering RNA-mediated knockdown of NF-kBp65 attenuates neuropathic pain following peripheral nerve injury in rats. Eur J Pharmacol, 2012; 682: 79-85
    • (2012) Eur J Pharmacol , vol.682 , pp. 79-85
    • Sun, T.1    Luo, J.2    Jia, M.3
  • 33
    • 33845353520 scopus 로고    scopus 로고
    • Injection of nuclear factor-kappa B decoy into the sciatic nerve suppresses mechanical allodynia and thermal hyperalgesia in a rat infammatory pain model
    • Inoue G, Ochiai N, Ohtori S et al: Injection of nuclear factor-kappa B decoy into the sciatic nerve suppresses mechanical allodynia and thermal hyperalgesia in a rat infammatory pain model. Spine (Phila Pa 1976), 2006; 31: 2904-8
    • (2006) Spine (Phila Pa , vol.1976 , Issue.31 , pp. 2904-2908
    • Inoue, G.1    Ochiai, N.2    Ohtori, S.3
  • 34
    • 84860662963 scopus 로고    scopus 로고
    • Inhibitor kappa B kinase beta dependent cytokine upregulation in nociceptive neurons contributes to nociceptive hypersensitivity after sciatic nerve injury
    • Kanngiesser M, Häussler A, Myrczek T et al: Inhibitor kappa B kinase beta dependent cytokine upregulation in nociceptive neurons contributes to nociceptive hypersensitivity after sciatic nerve injury. J Pain, 2012; 13: 485-97
    • (2012) J Pain , vol.13 , pp. 485-497
    • Kanngiesser, M.1    Häussler, A.2    Myrczek, T.3
  • 35
    • 67749147625 scopus 로고    scopus 로고
    • NF-kappaB mediated enhancement of potassium currents by the chemokine CXCL1/growth related oncogene in small diameter rat sensory neurons
    • Yang RH, Strong JA, Zhang JM: NF-kappaB mediated enhancement of potassium currents by the chemokine CXCL1/growth related oncogene in small diameter rat sensory neurons. Mol Pain, 2009; 5: 26
    • (2009) Mol Pain , vol.5 , pp. 26
    • Yang, R.H.1    Strong, J.A.2    Zhang, J.M.3
  • 36
    • 70350495611 scopus 로고    scopus 로고
    • Role of NFkappaB in an animal model of complex regional pain syndrome-type I (CRPS-I)
    • de Mos M, Laferrière A, Millecamps M et al: Role of NFkappaB in an animal model of complex regional pain syndrome-type I (CRPS-I). J Pain, 2009; 10: 1161-69
    • (2009) J Pain , vol.10 , pp. 1161-1169
    • de Mos, M.1    Laferrière, A.2    Millecamps, M.3
  • 37
    • 84875464198 scopus 로고    scopus 로고
    • Upregulation of nuclear factor of activated T-cells by nerve injury contributes to development of neuropathic pain
    • Cai YQ, Chen SR, Pan HL: Upregulation of nuclear factor of activated T-cells by nerve injury contributes to development of neuropathic pain. J Pharmacol Exp Ther, 2013; 345: 161-68
    • (2013) J Pharmacol Exp Ther , vol.345 , pp. 161-168
    • Cai, Y.Q.1    Chen, S.R.2    Pan, H.L.3
  • 38
    • 84871703725 scopus 로고    scopus 로고
    • Genetic enhancement of neuropathic and infammatory pain by forebrain upregulation of CREB-mediated transcription
    • Descalzi G, Fukushima H, Suzuki A et al: Genetic enhancement of neuropathic and infammatory pain by forebrain upregulation of CREB-mediated transcription. Mol Pain, 2012; 8: 90
    • (2012) Mol Pain , vol.8 , pp. 90
    • Descalzi, G.1    Fukushima, H.2    Suzuki, A.3
  • 39
    • 0142042954 scopus 로고    scopus 로고
    • Intrathecal injection of cAMP response element binding protein (CREB) antisense oligonucleotide attenuates tactile allodynia caused by partial sciatic nerve ligation
    • Ma W, Hatzis C, Eisenach JC: Intrathecal injection of cAMP response element binding protein (CREB) antisense oligonucleotide attenuates tactile allodynia caused by partial sciatic nerve ligation. Brain Res, 2003; 988: 97-104
    • (2003) Brain Res , vol.988 , pp. 97-104
    • Ma, W.1    Hatzis, C.2    Eisenach, J.C.3
  • 40
    • 84866488750 scopus 로고    scopus 로고
    • Tumor suppressor menin mediates peripheral nerve injury-induced neuropathic pain through potentiating synaptic plasticity
    • Xu S, Wu H, Wang X et al: Tumor suppressor menin mediates peripheral nerve injury-induced neuropathic pain through potentiating synaptic plasticity. Neuroscience, 2012; 223: 473-85
    • (2012) Neuroscience , vol.223 , pp. 473-485
    • Xu, S.1    Wu, H.2    Wang, X.3
  • 41
    • 84899634577 scopus 로고    scopus 로고
    • Menin regulates spinal glutamate-GABA balance through GAD65 contributing to neuropathic pain
    • Shen X, Liu Y, Xu S et al: Menin regulates spinal glutamate-GABA balance through GAD65 contributing to neuropathic pain. Pharmacol Rep, 2014; 66: 49-55
    • (2014) Pharmacol Rep , vol.66 , pp. 49-55
    • Shen, X.1    Liu, Y.2    Xu, S.3
  • 42
    • 0024869513 scopus 로고
    • AP1, a composite transcription factor implicated in abnormal growth control
    • Imler JL, Wasylyk B: AP1, a composite transcription factor implicated in abnormal growth control. Prog Growth Factor Res, 1989; 1: 69-77
    • (1989) Prog Growth Factor Res , vol.1 , pp. 69-77
    • Imler, J.L.1    Wasylyk, B.2
  • 43
    • 77957736469 scopus 로고    scopus 로고
    • Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability
    • Mucha M, Ooi L, Linley JE et al: Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability. J Neurosci, 2010; 30: 13235-45
    • (2010) J Neurosci , vol.30 , pp. 13235-13245
    • Mucha, M.1    Ooi, L.2    Linley, J.E.3
  • 44
    • 0037135287 scopus 로고    scopus 로고
    • Analysis of gene expression following spinal cord injury in rat using complementary DNA microarray
    • Tachibana T, Noguchi K, Ruda MA: Analysis of gene expression following spinal cord injury in rat using complementary DNA microarray. Neurosci Lett, 2002; 327: 133-37
    • (2002) Neurosci Lett , vol.327 , pp. 133-137
    • Tachibana, T.1    Noguchi, K.2    Ruda, M.A.3
  • 45
    • 0842342532 scopus 로고    scopus 로고
    • The efect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fbers of the rat following peripheral nerve injury
    • Kalmar B, Greensmith L, Malcangio M et al: The efect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fbers of the rat following peripheral nerve injury. Exp Neurol, 2003; 184: 636-47
    • (2003) Exp Neurol , vol.184 , pp. 636-647
    • Kalmar, B.1    Greensmith, L.2    Malcangio, M.3
  • 46
    • 84863598560 scopus 로고    scopus 로고
    • Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: Possible involvements in hypoxia-inducible factor 1a (HIF-1a)
    • Hsieh YL, Chou LW, Chang PL et al: Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1a (HIF-1a). J Comp Neurol, 2012; 520: 2903-16
    • (2012) J Comp Neurol , vol.520 , pp. 2903-2916
    • Hsieh, Y.L.1    Chou, L.W.2    Chang, P.L.3
  • 47
    • 84867850387 scopus 로고    scopus 로고
    • Neuronal damage and functional defcits are ameliorated by inhibition of aquaporin and HIF1a after traumatic brain injury (TBI)
    • Shenaq M, Kassem H, Peng C et al: Neuronal damage and functional defcits are ameliorated by inhibition of aquaporin and HIF1a after traumatic brain injury (TBI). J Neurol Sci, 2012; 323: 134-40
    • (2012) J Neurol Sci , vol.323 , pp. 134-140
    • Shenaq, M.1    Kassem, H.2    Peng, C.3
  • 48
    • 12344308311 scopus 로고    scopus 로고
    • Transient expression of hypoxia-inducible factor-1 alpha and target genes in peripheral nerves from diabetic rats
    • Chavez JC, Almhanna K, Berti-Mattera LN: Transient expression of hypoxia-inducible factor-1 alpha and target genes in peripheral nerves from diabetic rats. Neurosci Lett, 2005; 374: 179-82
    • (2005) Neurosci Lett , vol.374 , pp. 179-182
    • Chavez, J.C.1    Almhanna, K.2    Berti-Mattera, L.N.3
  • 49
    • 78851469601 scopus 로고    scopus 로고
    • DREAM regulates BDNF-dependent spinal sensitization
    • Rivera-Arconada I, Benedet T, Roza C et al: DREAM regulates BDNF-dependent spinal sensitization. Mol Pain, 2010; 6: 95
    • (2010) Mol Pain , vol.6 , pp. 95
    • Rivera-Arconada, I.1    Benedet, T.2    Roza, C.3
  • 50
    • 29244488758 scopus 로고    scopus 로고
    • Actions of brain-derived neurotrophic factor on spinal nociceptive transmission during infammation in the rat
    • Matayoshi S, Jiang N, Katafuchi T et al: Actions of brain-derived neurotrophic factor on spinal nociceptive transmission during infammation in the rat. J Physiol, 2005; 569: 685-95
    • (2005) J Physiol , vol.569 , pp. 685-695
    • Matayoshi, S.1    Jiang, N.2    Katafuchi, T.3
  • 51
    • 15544373279 scopus 로고    scopus 로고
    • Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury
    • Canudas AM, Pezzi S, Canals JM et al: Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury. Brain Res Mol Brain Res, 2005; 134: 147-5452.
    • (2005) Brain Res Mol Brain Res , vol.134 , pp. 147-154
    • Canudas, A.M.1    Pezzi, S.2    Canals, J.M.3
  • 52
    • 77955143610 scopus 로고    scopus 로고
    • Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: Role of brain-derived neurotrophic factor
    • Cao XH, Byun HS, Chen SR et al: Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor. J Neurochem, 2010; 114: 1460-75
    • (2010) J Neurochem , vol.114 , pp. 1460-1475
    • Cao, X.H.1    Byun, H.S.2    Chen, S.R.3
  • 53
    • 43549108996 scopus 로고    scopus 로고
    • Brain derived nerve growth factor induces spinal noradrenergic fber sprouting and enhances clonidine analgesia following nerve injury in rats
    • Hayashida K, Clayton BA, Johnson JE, Eisenach JC: Brain derived nerve growth factor induces spinal noradrenergic fber sprouting and enhances clonidine analgesia following nerve injury in rats. Pain, 2008; 136: 348-55
    • (2008) Pain , vol.136 , pp. 348-355
    • Hayashida, K.1    Clayton, B.A.2    Johnson, J.E.3    Eisenach, J.C.4
  • 54
    • 77955173213 scopus 로고    scopus 로고
    • Spinal alpha 2-adrenoceptor-mediated analgesia in neuropathic pain refects brain-derived nerve growth factor and changes in spinal cholinergic neuronal function
    • Hayashida K, Eisenach JC: Spinal alpha 2-adrenoceptor-mediated analgesia in neuropathic pain refects brain-derived nerve growth factor and changes in spinal cholinergic neuronal function. Anesthesiology, 2010; 113: 406-12
    • (2010) Anesthesiology , vol.113 , pp. 406-412
    • Hayashida, K.1    Eisenach, J.C.2
  • 55
    • 84875083000 scopus 로고    scopus 로고
    • BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state
    • Melemedjian OK, Tillu DV, Asiedu MN et al: BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Mol Pain, 2013; 9: 12
    • (2013) Mol Pain , vol.9 , pp. 12
    • Melemedjian, O.K.1    Tillu, D.V.2    Asiedu, M.N.3
  • 56
    • 77955501581 scopus 로고    scopus 로고
    • Is BDNF sufcient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization?
    • Biggs JE, Lu VB, Stebbing MJ et al: Is BDNF sufcient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization? Mol Pain, 2010; 6: 44
    • (2010) Mol Pain , vol.6 , pp. 44
    • Biggs, J.E.1    Lu, V.B.2    Stebbing, M.J.3
  • 57
    • 84875773449 scopus 로고    scopus 로고
    • Epigenetic regulation of BDNF expression in the primary sensory neurons after peripheral nerve injury: Implications in the development of neuropathic pain
    • Uchida H, Matsushita Y, Ueda H: Epigenetic regulation of BDNF expression in the primary sensory neurons after peripheral nerve injury: implications in the development of neuropathic pain. Neuroscience, 2013; 240: 147-54
    • (2013) Neuroscience , vol.240 , pp. 147-154
    • Uchida, H.1    Matsushita, Y.2    Ueda, H.3
  • 58
    • 0022516942 scopus 로고
    • A quantitative analysis of the interrelationships between subpopulations of rat sensory neurons containing arginine vasopressin or oxytocin and those containing substance P, fuorideresistant acid phosphatase or neuroflament protein
    • Kai-Kai MA, Anderton BH, Keen P: A quantitative analysis of the interrelationships between subpopulations of rat sensory neurons containing arginine vasopressin or oxytocin and those containing substance P, fuorideresistant acid phosphatase or neuroflament protein. Neuroscience, 1986; 18: 475-86
    • (1986) Neuroscience , vol.18 , pp. 475-486
    • Kai-Kai, M.A.1    Anderton, B.H.2    Keen, P.3
  • 59
    • 84896403843 scopus 로고    scopus 로고
    • Oxytocin activates calcium signaling in rat sensory neurons through a protein kinase C-dependent mechanism
    • Ayar A, Ozcan M, Alcin E et al: Oxytocin activates calcium signaling in rat sensory neurons through a protein kinase C-dependent mechanism. J Physiol Biochem, 2014; 70: 43-48
    • (2014) J Physiol Biochem , vol.70 , pp. 43-48
    • Ayar, A.1    Ozcan, M.2    Alcin, E.3
  • 60
    • 77953773979 scopus 로고    scopus 로고
    • Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse
    • Schorscher-Petcu A, Sotocinal S, Ciura S et al: Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse. J Neurosci, 2010; 30: 8274-84
    • (2010) J Neurosci , vol.30 , pp. 8274-8284
    • Schorscher-Petcu, A.1    Sotocinal, S.2    Ciura, S.3
  • 61
    • 84885455675 scopus 로고    scopus 로고
    • Long-lasting spinal oxytocin analgesia is ensured by the stimulation of allopregnanolone synthesis which potentiates GABAA receptor-mediated synaptic inhibition
    • Juif PE, Breton JD, Rajalu M et al: Long-lasting spinal oxytocin analgesia is ensured by the stimulation of allopregnanolone synthesis which potentiates GABAA receptor-mediated synaptic inhibition. J Neurosci, 2013; 33: 16617-26
    • (2013) J Neurosci , vol.33 , pp. 16617-16626
    • Juif, P.E.1    Breton, J.D.2    Rajalu, M.3
  • 62
    • 79955467284 scopus 로고    scopus 로고
    • Oxytocin, but not arginine vasopressin is involving in the antinociceptive role of hypothalamic supraoptic nucleus
    • Yang J, Liang JY, Zhang XY et al: Oxytocin, but not arginine vasopressin is involving in the antinociceptive role of hypothalamic supraoptic nucleus. Peptides, 2011; 32: 1042-46
    • (2011) Peptides , vol.32 , pp. 1042-1046
    • Yang, J.1    Liang, J.Y.2    Zhang, X.Y.3
  • 63
    • 84879783346 scopus 로고    scopus 로고
    • Neurohormonal efects of oxytocin and vasopressin receptor agonists on spinal pain processing in male rats
    • Juif PE, Poisbeau P: Neurohormonal efects of oxytocin and vasopressin receptor agonists on spinal pain processing in male rats. Pain, 2013; 154: 1449-56
    • (2013) Pain , vol.154 , pp. 1449-1456
    • Juif, P.E.1    Poisbeau, P.2
  • 64
    • 84866290358 scopus 로고    scopus 로고
    • Central administration of oxytocin reduces hyperalgesia in mice: Implication for cannabinoid and opioid systems
    • Russo R, D'Agostino G, Mattace Raso G et al: Central administration of oxytocin reduces hyperalgesia in mice: implication for cannabinoid and opioid systems. Peptides, 2012; 38: 81-88
    • (2012) Peptides , vol.38 , pp. 81-88
    • Russo, R.1    D'Agostino, G.2    Mattace Raso, G.3
  • 65
    • 84878872432 scopus 로고    scopus 로고
    • Epigenetic regulation of the oxytocin receptor gene: Implications for behavioral neuroscience
    • Kumsta R, Hummel E, Chen FS, Heinrichs M: Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience. Front Neurosci, 2013; 7: 83
    • (2013) Front Neurosci , vol.7 , pp. 83
    • Kumsta, R.1    Hummel, E.2    Chen, F.S.3    Heinrichs, M.4
  • 66
    • 74449093596 scopus 로고    scopus 로고
    • Neuron-restrictive silencer factor causes epigenetic silencing of Kv4.3 gene after peripheral nerve injury
    • Uchida H, Sasaki K, Ma L, Ueda H: Neuron-restrictive silencer factor causes epigenetic silencing of Kv4.3 gene after peripheral nerve injury. Neuroscience, 2010; 166: 1-4
    • (2010) Neuroscience , vol.166 , pp. 1-4
    • Uchida, H.1    Sasaki, K.2    Ma, L.3    Ueda, H.4
  • 67
    • 79953064829 scopus 로고    scopus 로고
    • Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury
    • Rose K, Ooi L, Dalle C et al: Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury. Pain, 2011; 152: 742-54
    • (2011) Pain , vol.152 , pp. 742-754
    • Rose, K.1    Ooi, L.2    Dalle, C.3
  • 68
    • 84880875131 scopus 로고    scopus 로고
    • A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary aferent neurons
    • Zhao X, Tang Z, Zhang H et al: A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary aferent neurons. Nat Neurosci, 2013; 16: 1024-31
    • (2013) Nat Neurosci , vol.16 , pp. 1024-1031
    • Zhao, X.1    Tang, Z.2    Zhang, H.3
  • 69
    • 77950632304 scopus 로고    scopus 로고
    • Epigenetic gene silencing underlies C-fber dysfunctions in neuropathic pain
    • Uchida H, Ma L, Ueda H: Epigenetic gene silencing underlies C-fber dysfunctions in neuropathic pain. J Neurosci, 2010; 30: 4806-14
    • (2010) J Neurosci , vol.30 , pp. 4806-4814
    • Uchida, H.1    Ma, L.2    Ueda, H.3
  • 70
    • 84885582441 scopus 로고    scopus 로고
    • HDAC inhibitors restore C-fbre sensitivity in experimental neuropathic pain model
    • Matsushita Y, Araki K, Omotuyi OI et al: HDAC inhibitors restore C-fbre sensitivity in experimental neuropathic pain model. Br J Pharmacol, 2013; 170: 991-98
    • (2013) Br J Pharmacol , vol.170 , pp. 991-998
    • Matsushita, Y.1    Araki, K.2    Omotuyi, O.I.3
  • 72
    • 33747611426 scopus 로고    scopus 로고
    • Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: A possible mechanism for the analgesic effect of L-acetylcarnitine
    • Chiechio S, Copani A, De Petris L et al: Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine. Mol Pain, 2006; 2: 20
    • (2006) Mol Pain , vol.2 , pp. 20
    • Chiechio, S.1    Copani, A.2    de Petris, L.3
  • 73
    • 84904333859 scopus 로고    scopus 로고
    • Treatment of CRPS with spinal cord stimulation of the dorsal root ganglion: A case series
    • 2012
    • Van Buyten JP, Smet I, Liem L et al: Treatment of CRPS with spinal cord stimulation of the dorsal root ganglion: a case series. MK0009A-EN 2012; 2012: 1-6
    • (2012) MK0009A-EN , pp. 1-6
    • van Buyten, J.P.1    Smet, I.2    Liem, L.3
  • 74
    • 77953633289 scopus 로고    scopus 로고
    • Noradrenaline stimulates ATP release from DRG neurons by targeting beta(3) adrenoceptors as a factor of neuropathic pain
    • Kanno T, Yaguchi T, Nishizaki T: Noradrenaline stimulates ATP release from DRG neurons by targeting beta(3) adrenoceptors as a factor of neuropathic pain. J Cell Physiol, 2010; 224: 345-51
    • (2010) J Cell Physiol , vol.224 , pp. 345-351
    • Kanno, T.1    Yaguchi, T.2    Nishizaki, T.3
  • 75
    • 81355123257 scopus 로고    scopus 로고
    • Noradrenaline regulates substance P release from rat dorsal root ganglion neurons in vitro
    • Wang YJ, Li XF, Ding F et al: Noradrenaline regulates substance P release from rat dorsal root ganglion neurons in vitro. Neurosci Bull, 2011; 27: 300-6
    • (2011) Neurosci Bull , vol.27 , pp. 300-306
    • Wang, Y.J.1    Li, X.F.2    Ding, F.3
  • 76
    • 84865648193 scopus 로고    scopus 로고
    • Clenbuterol upregulates histone demethylase JHDM2a via the b2-adrenoceptor/cAMP/PKA/p-CREB signaling pathway
    • Li Y, He J, Sui S et al: Clenbuterol upregulates histone demethylase JHDM2a via the b2-adrenoceptor/cAMP/PKA/p-CREB signaling pathway. Cell Signal, 2012; 24: 2297-306
    • (2012) Cell Signal , vol.24 , pp. 2297-2306
    • Li, Y.1    He, J.2    Sui, S.3
  • 77
    • 34347406314 scopus 로고    scopus 로고
    • Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: A role for DNA methylation in Sp1-dependent regulation
    • Michelotti GA, Brinkley DM, Morris DP et al: Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation. FASEB J, 2007; 21: 1979-93
    • (2007) FASEB J , vol.21 , pp. 1979-1993
    • Michelotti, G.A.1    Brinkley, D.M.2    Morris, D.P.3
  • 78
    • 44149101892 scopus 로고    scopus 로고
    • Noradrenergic and opioidergic alterations in neuropathy in diferent rat strains
    • Herradon G, Ezquerra L, Nguyen T et al: Noradrenergic and opioidergic alterations in neuropathy in diferent rat strains. Neurosci Lett, 2008; 438: 186-89
    • (2008) Neurosci Lett , vol.438 , pp. 186-189
    • Herradon, G.1    Ezquerra, L.2    Nguyen, T.3
  • 79
    • 77954706653 scopus 로고    scopus 로고
    • Central opioidergic neurotransmission in complex regional pain syndrome
    • Klega A, Eberle T, Buchholz HG et al: Central opioidergic neurotransmission in complex regional pain syndrome. Neurology, 2010; 75: 129-36
    • (2010) Neurology , vol.75 , pp. 129-136
    • Klega, A.1    Eberle, T.2    Buchholz, H.G.3
  • 80
    • 84887076576 scopus 로고    scopus 로고
    • Impaired recognition of social emotion in patients with complex regional pain syndrome
    • Shin NY, Kang DH, Jang JH et al: Impaired recognition of social emotion in patients with complex regional pain syndrome. J Pain, 2013; 14: 1304-9
    • (2013) J Pain , vol.14 , pp. 1304-1309
    • Shin, N.Y.1    Kang, D.H.2    Jang, J.H.3
  • 81
    • 84861892120 scopus 로고    scopus 로고
    • Stress-induced epigenetic regulation of k-opioid receptor gene involves transcription factor c-Myc
    • Flaisher-Grinberg S, Persaud SD, Loh HH, Wei LN: Stress-induced epigenetic regulation of k-opioid receptor gene involves transcription factor c-Myc. Proc Natl Acad Sci USA, 2012; 109: 9167-72
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 9167-9172
    • Flaisher-Grinberg, S.1    Persaud, S.D.2    Loh, H.H.3    Wei, L.N.4
  • 82
    • 64949083602 scopus 로고    scopus 로고
    • Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy
    • Thakor DK, Lin A, Matsuka Y et al: Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy. Mol Pain, 2009; 5: 14
    • (2009) Mol Pain , vol.5 , pp. 14
    • Thakor, D.K.1    Lin, A.2    Matsuka, Y.3
  • 83
    • 0030891726 scopus 로고    scopus 로고
    • Complex regional pain syndrome (refex sympathetic dystrophy and causalgia): Management with the calcium channel blocker nifedipine and/or the alpha-sympathetic blocker phenoxybenzamine in 59 patients
    • Muizelaar JP, Kleyer M, Hertogs IA, DeLange DC: Complex regional pain syndrome (refex sympathetic dystrophy and causalgia): management with the calcium channel blocker nifedipine and/or the alpha-sympathetic blocker phenoxybenzamine in 59 patients. Clin Neurol Neurosurg, 1997; 99: 26-30
    • (1997) Clin Neurol Neurosurg , vol.99 , pp. 26-30
    • Muizelaar, J.P.1    Kleyer, M.2    Hertogs, I.A.3    Delange, D.C.4
  • 84
    • 84863116823 scopus 로고    scopus 로고
    • 2+ channel activity and nociceptive input in neuropathic pain
    • 2+ channel activity and nociceptive input in neuropathic pain. J Biol Chem, 2012; 287: 6002-13
    • (2012) J Biol Chem , vol.287 , pp. 6002-6013
    • Li, L.1    Cao, X.H.2    Chen, S.R.3
  • 85
    • 84884313867 scopus 로고    scopus 로고
    • Expression of background potassium channels in rat DRG is cell-specifc and down-regulated in a neuropathic pain model
    • Pollema-Mays SL, Centeno MV, Ashford CJ et al: Expression of background potassium channels in rat DRG is cell-specifc and down-regulated in a neuropathic pain model. Mol Cell Neurosci, 2013; 57C: 1-9
    • (2013) Mol Cell Neurosci , vol.57 C , pp. 1-9
    • Pollema-Mays, S.L.1    Centeno, M.V.2    Ashford, C.J.3
  • 86
    • 67649378414 scopus 로고    scopus 로고
    • ATP-sensitive potassium currents in rat primary aferent neurons: Biophysical, pharmacological properties, and alterations by painful nerve injury
    • Kawano T, Zoga V, McCallum JB et al: ATP-sensitive potassium currents in rat primary aferent neurons: biophysical, pharmacological properties, and alterations by painful nerve injury. Neuroscience, 2009; 162: 431-43
    • (2009) Neuroscience , vol.162 , pp. 431-443
    • Kawano, T.1    Zoga, V.2    McCallum, J.B.3
  • 87
    • 84879752715 scopus 로고    scopus 로고
    • Evidence for glutamate as a neuroglial transmitter within sensory ganglia
    • Kung LH, Gong K, Adedoyin M et al: Evidence for glutamate as a neuroglial transmitter within sensory ganglia. PLoS One, 2013; 8: e68312
    • (2013) PLoS One , vol.8
    • Kung, L.H.1    Gong, K.2    Adedoyin, M.3
  • 88
    • 84869087242 scopus 로고    scopus 로고
    • Peripheral nerve injury decreases the expression of metabolic glutamate receptor 7 in dorsal root ganglion neurons
    • Li JY, Wang X, Ji PT et al: Peripheral nerve injury decreases the expression of metabolic glutamate receptor 7 in dorsal root ganglion neurons. Neurosci Lett, 2012; 531: 52-56
    • (2012) Neurosci Lett , vol.531 , pp. 52-56
    • Li, J.Y.1    Wang, X.2    Ji, P.T.3
  • 89
    • 0036549258 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 upregulation in A-fbers after spinal nerve injury: 2-methyl-6-(phenylethynyl)- pyridine (MPEP) reverses the induced thermal hyperalgesia
    • Hudson LJ, Bevan S, McNair K et al: Metabotropic glutamate receptor 5 upregulation in A-fbers after spinal nerve injury: 2-methyl-6-(phenylethynyl)- pyridine (MPEP) reverses the induced thermal hyperalgesia. J Neurosci, 2002; 22: 2660-68
    • (2002) J Neurosci , vol.22 , pp. 2660-2668
    • Hudson, L.J.1    Bevan, S.2    McNair, K.3
  • 90
    • 56449130117 scopus 로고    scopus 로고
    • Ketamine as an adjuvant in sympathetic blocks for management of central sensitization following peripheral nerve injury
    • Sunder RA, Toshniwal G, Dureja GP: Ketamine as an adjuvant in sympathetic blocks for management of central sensitization following peripheral nerve injury. J Brachial Plex Peripher Nerve Inj, 2008; 3: 22
    • (2008) J Brachial Plex Peripher Nerve Inj , vol.3 , pp. 22
    • Sunder, R.A.1    Toshniwal, G.2    Dureja, G.P.3
  • 91
    • 77950537328 scopus 로고    scopus 로고
    • Transcriptional regulation of type-2 metabotropic glutamate receptors: An epigenetic path to novel treatments for chronic pain
    • Chiechio S, Copani A, Zammataro M et al: Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain. Trends Pharmacol Sci, 2010; 31: 153-60
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 153-160
    • Chiechio, S.1    Copani, A.2    Zammataro, M.3
  • 92
    • 13544277546 scopus 로고    scopus 로고
    • Role of CpG islands in the up-regulation of NMDA receptor NR2B gene expression following chronic ethanol treatment of cultured cortical neurons of mice
    • Marutha Ravindran CR, Ticku MK: Role of CpG islands in the up-regulation of NMDA receptor NR2B gene expression following chronic ethanol treatment of cultured cortical neurons of mice. Neurochem Int, 2005; 46: 313-27
    • (2005) Neurochem Int , vol.46 , pp. 313-327
    • Marutha Ravindran, C.R.1    Ticku, M.K.2
  • 93
    • 45849100495 scopus 로고    scopus 로고
    • GABAA receptor modulation in dorsal root ganglia in vivo afects chronic pain after nerve injury
    • Naik AK, Pathirathna S, Jevtovic-Todorovic V: GABAA receptor modulation in dorsal root ganglia in vivo afects chronic pain after nerve injury. Neuroscience, 2008; 154: 1539-53
    • (2008) Neuroscience , vol.154 , pp. 1539-1553
    • Naik, A.K.1    Pathirathna, S.2    Jevtovic-Todorovic, V.3
  • 94
    • 33745230058 scopus 로고    scopus 로고
    • Vector-mediated gene transfer to express inhibitory neurotransmitters in dorsal root ganglion reduces pain in a rodent model of lumbar radiculopathy
    • Lee JY, Fink DJ, Mata M: Vector-mediated gene transfer to express inhibitory neurotransmitters in dorsal root ganglion reduces pain in a rodent model of lumbar radiculopathy. Spine (Phila Pa 1976), 2006; 31: 1555-58
    • (2006) Spine (Phila Pa , vol.1976 , Issue.31 , pp. 1555-1558
    • Lee, J.Y.1    Fink, D.J.2    Mata, M.3


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