Vector-mediated gene transfer to express inhibitory neurotransmitters in dorsal root ganglion reduces pain in a rodent model of lumbar radiculopathy

Spine

Volumn 31, Issue 14, 2006, Pages 1555-1558

  Lee, John Y K ^a   Fink, David J ^b   Mata, Marina ^b,c  

^a PA Hospital   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

Enkephalin; Gamma aminobutyric acid; Gene therapy; Glutamic acid decarboxylase; Herpes simplex virus; Lumbar radiculopathy; Pain

Indexed keywords

GLUTAMATE DECARBOXYLASE; HERPESVIRUS VECTOR; PROENKEPHALIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; DRUG EFFECT; EXPERIMENTAL ANIMAL; FOOT; GENE TRANSFER; HERPES SIMPLEX VIRUS; IN VIVO STUDY; LIGATION; LOW BACK PAIN; LUMBAR SPINAL CORD; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADICULAR PAIN; RADICULOPATHY; RAT; RODENT; VENTRAL ROOT; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; ENKEPHALINS; FOOT; GANGLIA, SPINAL; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLUTAMATE DECARBOXYLASE; HYPERESTHESIA; INJECTIONS, SUBCUTANEOUS; LIGATION; LUMBOSACRAL REGION; PAIN; PROTEIN PRECURSORS; RADICULOPATHY; RATS; RATS, SPRAGUE-DAWLEY; SIMPLEXVIRUS; SPINAL NERVE ROOTS;

EID: 33745230058     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/01.brs.0000222060.88919.58     Document Type: Article

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