Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury

Pain

Volumn 152, Issue 4, 2011, Pages 742-754

  Rose, Kirstin ^a   Ooi, Lezanne ^a   Dalle, Carine ^a,b,c   Robertson, Brian ^a   Wood, Ian C ^a   Gamper, Nikita ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

DRG; KCNQ; M current; Neuropathic pain; REST; Sensory neuron

Indexed keywords

10,10 BIS(4 PYRIDINYLMETHYL) 9(10H) ANTHRACENONE; FLUPIRTINE; LIDOCAINE; M CHANNEL; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KV7.2; REPRESSOR ELEMENT 1 SILENCING TRANSCRIPTION FACTOR; REPRESSOR PROTEIN; RETIGABINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; GENE EXPRESSION; HYPERALGESIA; MALE; NERVE EXCITABILITY; NERVE LIGATION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL GANGLION; TRANSCRIPTION REGULATION;

AMINOPYRIDINES; ANALGESICS; ANALYSIS OF VARIANCE; ANESTHETICS, LOCAL; ANIMALS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOPROTEINS; HYPERALGESIA; INDOLES; KCNQ2 POTASSIUM CHANNEL; LECTINS; LIDOCAINE; MALE; MEMBRANE POTENTIALS; NEUROFILAMENT PROTEINS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; REPRESSOR PROTEINS; RNA, MESSENGER; SCIATIC NEUROPATHY; TRPV CATION CHANNELS;

EID: 79953064829     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2010.12.028     Document Type: Article

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