Discovery of a negative allosteric modulator of GABAB receptors

ACS Medicinal Chemistry Letters

Volumn 5, Issue 7, 2014, Pages 742-747

  Chen, Lin Hai ^a   Sun, Bing ^b   Zhang, Yang ^b   Xu, Tong Jie ^b   Xia, Zhi Xiong ^b   Liu, Jian Feng ^b   Nan, Fa Jun ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

CGP7930; negative allosteric modulator; keto acid

Indexed keywords

2,6 DI TERT BUTYL 4 (3 HYDROXY 2,2 DIMETHYLPROPYL)PHENOL; 4 AMINOBUTYRIC ACID B RECEPTOR; BACLOFEN; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 5; MITOGEN ACTIVATED PROTEIN KINASE; N,N' DICYCLOPENTYL 2 METHYLTHIO 5 NITRO 4,6 PYRIMIDINEDIAMINE;

ALLOSTERISM; ARTICLE; BINDING SITE; HEK293 CELL LINE; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING;

EID: 84904319445     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml500162z     Document Type: Article

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