Characterization of [3H]-CGP54626A binding to heterodimeric GABAB receptors stably expressed in mammalian cells

British Journal of Pharmacology

Volumn 131, Issue 8, 2000, Pages 1766-1774

  Green, Andrew ^a   Walls, Steven ^a   Wise, Alan ^a   Green, Richard H ^a   Martin, Amanda K ^a   Marshall, Fiona H ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

G protein coupled receptor; Heterodimers; Human receptors; Ligand binding; Pharmacological characterization; Stable cell lines; Whole cell binding

Indexed keywords

3 AMINOPROPANEPHOSPHINIC ACID; 3 AMINOPROPYL(CYCLOHEXYLMETHYL)PHOSPHINIC ACID; 3 AMINOPROPYL(DIETHOXYMETHYL)PHOSPHINIC ACID; 3 AMINOPROPYL(METHYL)PHOSPHINIC ACID; 3 AMINOPROPYLBUTYLPHOSPHINIC ACID; 4 AMINOBUTANEPHOSPHONIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 5,5 DIMETHYL 2 MORPHOLINEACETIC ACID; BACLOFEN; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; CGP 46381; CGP 51176; CGP 54626A; RECEPTOR SUBTYPE; SACLOFEN; UNCLASSIFIED DRUG; [3 (3,4 DICHLOROBENZYLAMINO)PROPYL](DIETHOXYMETHYL)PHOSPHINIC ACID; [3 AMINO 2 HYDROXYPROPYL](CYCLOHEXYLMETHYL)PHOSPHINIC ACID; [3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL](CYCLOHEXYLMETHYL)PHOSPHINIC ACID;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIMERIZATION; DRUG RECEPTOR BINDING; LIGAND BINDING; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY;

EID: 0034528420     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703755     Document Type: Article

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