-
1
-
-
0034638766
-
Pharmacogenetics and adverse drug reactions
-
Meyer U. Pharmacogenetics and adverse drug reactions. Lancet 2000;356:1667-71
-
(2000)
Lancet
, vol.356
, pp. 1667-1671
-
-
Meyer, U.1
-
2
-
-
0001221024
-
Some statistical data on atypical cholinesterase of human serum
-
Kalow W, Gunn D. Some statistical data on atypical cholinesterase of human serum. Ann Hum Genet 1959;23:239-50
-
(1959)
Ann Hum Genet
, vol.23
, pp. 239-250
-
-
Kalow, W.1
Gunn, D.2
-
3
-
-
0037421590
-
Pharmacogenomics - drug disposition, drug targets, and side effects
-
Evans W, McLeod H. Pharmacogenomics - drug disposition, drug targets, and side effects. N Engl J Med 2003;348:538-49
-
(2003)
N Engl J Med
, vol.348
, pp. 538-549
-
-
Evans, W.1
McLeod, H.2
-
4
-
-
26444539817
-
Genetic control of isoniazid metabolism in man
-
Evans D, Manley K, McKusick V. Genetic control of isoniazid metabolism in man. Br Med J 1960;2:485-91
-
(1960)
Br Med J
, vol.2
, pp. 485-491
-
-
Evans, D.1
Manley, K.2
McKusick, V.3
-
5
-
-
0024523831
-
Pharmacogenetic perspectives gained from twin and family studies
-
Vesell E. Pharmacogenetic perspectives gained from twin and family studies. Pharmacol Ther 1989;41:535-52
-
(1989)
Pharmacol Ther
, vol.41
, pp. 535-552
-
-
Vesell, E.1
-
6
-
-
0022972654
-
Internal duplication and homology with bacterial transport proteins in the MDR1 (P-glycoprotein) gene from multidrugresistant human cells
-
Chen C, Chin J, Ueda K, et al. Internal duplication and homology with bacterial transport proteins in the MDR1 (P-glycoprotein) gene from multidrugresistant human cells. Cell 1986;47:381-9
-
(1986)
Cell
, vol.47
, pp. 381-389
-
-
Chen, C.1
Chin, J.2
Ueda, K.3
-
8
-
-
0033980182
-
P-glycoprotein: A defense mechanism limiting oral bioavailability and CNS accumulation of drugs
-
Fromm M. P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs. Int J Clin Pharmacol Ther 2000;38:69-74
-
(2000)
Int J Clin Pharmacol Ther
, vol.38
, pp. 69-74
-
-
Fromm, M.1
-
9
-
-
0023447098
-
Cellular localization of the multidrugresistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, et al. Cellular localization of the multidrugresistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci USA 1987;84:7735-8
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
-
10
-
-
0023153149
-
The human multidrug resistance (MDR1) gene: CDNA cloning and transcription initiation
-
Ueda K, Clark D, Chen C, et al. The human multidrug resistance (MDR1) gene: cDNA cloning and transcription initiation. J Biol Chem 1987;262:505-8
-
(1987)
J Biol Chem
, vol.262
, pp. 505-508
-
-
Ueda, K.1
Clark, D.2
Chen, C.3
-
11
-
-
0031808785
-
Zidovudine azidoreductase in human liver microsomes: Activation by ethacrynic acid, dipyridamole, and indomethacin by HIV protease inhibitors
-
Fayz S, Inaba T. Zidovudine azidoreductase in human liver microsomes: activation by ethacrynic acid, dipyridamole, and indomethacin by HIV protease inhibitors. Antimicrob Agents Chemother 1998;42:1654-8
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 1654-1658
-
-
Fayz, S.1
Inaba, T.2
-
12
-
-
43649102537
-
A review of the pharmacokinetics of abacavir
-
Yuen G, Weller S, Pakes G. A review of the pharmacokinetics of abacavir. Clin Pharmacokinet 2008;47:351-71
-
(2008)
Clin Pharmacokinet
, vol.47
, pp. 351-371
-
-
Yuen, G.1
Weller, S.2
Pakes, G.3
-
13
-
-
33745929357
-
Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: A pilot study
-
Anderson P, Lamba J, Aquilante C, et al. Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: a pilot study. J Acquir Immune Defic Syndr 2006;42:441-9
-
(2006)
J Acquir Immune Defic Syndr
, vol.42
, pp. 441-449
-
-
Anderson, P.1
Lamba, J.2
Aquilante, C.3
-
14
-
-
0036811774
-
The abacavir hypersensitivity reaction: A review
-
Clay P. The abacavir hypersensitivity reaction: a review. Clin Ther 2002;24:1502-14
-
(2002)
Clin Ther
, vol.24
, pp. 1502-1514
-
-
Clay, P.1
-
15
-
-
0032840959
-
Abacavir rechallenge has to be avoided in case of hypersensitivity reaction
-
Escaut L, Liotier J, Albengres E, et al. Abacavir rechallenge has to be avoided in case of hypersensitivity reaction. AIDS 1999;13:1419-20
-
(1999)
AIDS
, vol.13
, pp. 1419-1420
-
-
Escaut, L.1
Liotier, J.2
Albengres, E.3
-
16
-
-
0037006623
-
Association between presence of HLAB*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse transcriptase inhibitor abacavir
-
Mallal S, Nolan D, Witt C, et al. Association between presence of HLAB*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse transcriptase inhibitor abacavir. Lancet 2002;359:727-32
-
(2002)
Lancet
, vol.359
, pp. 727-732
-
-
Mallal, S.1
Nolan, D.2
Witt, C.3
-
17
-
-
38949196447
-
PREDICT-1 Study Team. HLA-B*5701 screening for hypersensitivity to abacavir
-
Mallal S, Phillips E, Carosi G, et al. PREDICT-1 Study Team. HLA-B*5701 screening for hypersensitivity to abacavir. N Engl J Med 2008;358:568-79
-
(2008)
N Engl J Med
, vol.358
, pp. 568-579
-
-
Mallal, S.1
Phillips, E.2
Carosi, G.3
-
18
-
-
42549131532
-
High sensitivity of human leukocyte antigen- B*5701 as a marker for immunogenetically confirmed abacavir hypersensitivity in white and black patients
-
Saag M, Balu R, Phillips E, et al. High sensitivity of human leukocyte antigen- B*5701 as a marker for immunogenetically confirmed abacavir hypersensitivity in white and black patients. Clin Infect Dis 2008;46:1111-18
-
(2008)
Clin Infect Dis
, vol.46
, pp. 1111-1118
-
-
Saag, M.1
Balu, R.2
Phillips, E.3
-
19
-
-
33745295856
-
Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study
-
Rauch A, Nolan D, Martin A, et al. Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study. Clin Infect Dis 2006;43:99-102
-
(2006)
Clin Infect Dis
, vol.43
, pp. 99-102
-
-
Rauch, A.1
Nolan, D.2
Martin, A.3
-
20
-
-
34247636623
-
Prospective genetic screening for human leukocyte antigen-B*5701 avoid abacavir hypersensitivity in the ethnically mixed French HIV population
-
Zucman D, Truchis P, Majerholc C, et al. Prospective genetic screening for human leukocyte antigen-B*5701 avoid abacavir hypersensitivity in the ethnically mixed French HIV population. J Acquir Immune Defic Syndr 2007;45:1-3
-
(2007)
J Acquir Immune Defic Syndr
, vol.45
, pp. 1-3
-
-
Zucman, D.1
Truchis, P.2
Majerholc, C.3
-
21
-
-
72649086454
-
Successful implementation of a national HLA-B*5701 genetic testing service in Canada
-
Lalonde R, Thomas R, Rachlis A, et al. Successful implementation of a national HLA-B*5701 genetic testing service in Canada. Tissue Antigens 2009;75:12-18
-
(2009)
Tissue Antigens
, vol.75
, pp. 12-18
-
-
Lalonde, R.1
Thomas, R.2
Rachlis, A.3
-
22
-
-
36349024340
-
Prospective HLA-B*5701 screening and abacavir hypersensitivity: A single centre experience
-
Waters L, Mandalia S, Gazzard B, et al. Prospective HLA-B*5701 screening and abacavir hypersensitivity: a single centre experience. AIDS 2007;21:2533-4
-
(2007)
AIDS
, vol.21
, pp. 2533-2534
-
-
Waters, L.1
Mandalia, S.2
Gazzard, B.3
-
23
-
-
77954745358
-
Use of the HCP5 single nucleotide polymorphism to predict hypersensitivity reactions to abacavir: Correlation with HLA-B*5701
-
Rodriguez-Novoa S, Cuenca L, Morello J, et al Use of the HCP5 single nucleotide polymorphism to predict hypersensitivity reactions to abacavir: correlation with HLA-B*5701. J Antimicrob Chemother 2010 65 1567-9
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 1567-1569
-
-
Rodriguez-Novoa, S.1
Cuenca, L.2
Morello, J.3
-
24
-
-
34249984379
-
The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: The first 4 years
-
Nelson M, Katlama C, Montaner J, et al. The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years. AIDS 2007;21:1273-81
-
(2007)
AIDS
, vol.21
, pp. 1273-1281
-
-
Nelson, M.1
Katlama, C.2
Montaner, J.3
-
25
-
-
10744221111
-
Renal tubular dysfunction associated with tenofovir therapy: Report of 7 cases
-
Peyriere H, Reynes J, Rouanet I, et al. Renal tubular dysfunction associated with tenofovir therapy: report of 7 cases. J Acquir Immune Defic Syndr 2004;35:269-73
-
(2004)
J Acquir Immune Defic Syndr
, vol.35
, pp. 269-273
-
-
Peyriere, H.1
Reynes, J.2
Rouanet, I.3
-
26
-
-
0036895460
-
Fanconi syndrome and renal failure induced by tenofovir: A first case report
-
Verhelst D, Monge M, Meynard J, et al. Fanconi syndrome and renal failure induced by tenofovir: a first case report. Am J Kidney Dis 2002;40:1331-3
-
(2002)
Am J Kidney Dis
, vol.40
, pp. 1331-1333
-
-
Verhelst, D.1
Monge, M.2
Meynard, J.3
-
27
-
-
64549084582
-
Kidney tubular abnormalities in the absence of impaired glomerular function in HIV patients treated with tenofovir
-
Labarga P, Barreiro P, Martin-Carbonero L, et al. Kidney tubular abnormalities in the absence of impaired glomerular function in HIV patients treated with tenofovir. AIDS 2009;23:689-96
-
(2009)
AIDS
, vol.23
, pp. 689-696
-
-
Labarga, P.1
Barreiro, P.2
Martin-Carbonero, L.3
-
28
-
-
39349112711
-
Greater tenofovir-associated renal function decline with protease inhibitorbased versus non-nucleoside reversetranscriptase inhibitor based therapy
-
Goicoechea M, Liu S, Best B, et al. Greater tenofovir-associated renal function decline with protease inhibitorbased versus non-nucleoside reversetranscriptase inhibitor based therapy. J Infect Dis 2008;197:102-8
-
(2008)
J Infect Dis
, vol.197
, pp. 102-108
-
-
Goicoechea, M.1
Liu, S.2
Best, B.3
-
29
-
-
84886487823
-
Bone mineral density effects of randomized regimen and nucleoside reverse transcriptase inhibitor selection from ACTG A5142
-
Huang J, Hughes M, Riddler S, et al. Bone mineral density effects of randomized regimen and nucleoside reverse transcriptase inhibitor selection from ACTG A5142. HIV Clin Trials 2013;14:224-34
-
(2013)
HIV Clin Trials
, vol.14
, pp. 224-234
-
-
Huang, J.1
Hughes, M.2
Riddler, S.3
-
30
-
-
33749531758
-
Mechanism of active renal tubular efflux of tenofovir
-
Ray A, Cihlar T, Robinson K, et al. Mechanism of active renal tubular efflux of tenofovir. Antimicrob Agents Chemother 2006;50:3297-304
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 3297-3304
-
-
Ray, A.1
Cihlar, T.2
Robinson, K.3
-
31
-
-
0034852408
-
Human renal organic anion transporter 1 (hOAT1) and its role in the nephrotoxicity of antiviral nucleotide analogs
-
Cihlar T, Ho E, Lin D, Mulato A. Human renal organic anion transporter 1 (hOAT1) and its role in the nephrotoxicity of antiviral nucleotide analogs. Nucleosides Nucleotides Nucleic Acids 2001;20:641-8
-
(2001)
Nucleosides Nucleotides Nucleic Acids
, vol.20
, pp. 641-648
-
-
Cihlar, T.1
Ho, E.2
Lin, D.3
Mulato, A.4
-
32
-
-
12144257103
-
Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
-
van Aubel R, Smeets P, van den Heuvel P, et al. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am J Physiol Renal Physiol 2005;288:F327-33
-
(2005)
Am J Physiol Renal Physiol
, vol.288
-
-
Van Aubel, R.1
Smeets, P.2
Van Den Heuvel, P.3
-
33
-
-
30344432397
-
Multidrug resistanceassociated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites
-
Mallants R, van Oosterwyck K, Van Vaeck L, et al. Multidrug resistanceassociated protein 2 (MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites. Xenobiotica 2005;35:1055-66
-
(2005)
Xenobiotica
, vol.35
, pp. 1055-1066
-
-
Mallants, R.1
Van Oosterwyck, K.2
Van Vaeck, L.3
-
34
-
-
0034765470
-
Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule
-
Miller D. Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule. J Pharmacol Exp Ther 2001;299:567-74
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 567-574
-
-
Miller, D.1
-
35
-
-
33846420624
-
Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir
-
Imaoka T, Kusuhara H, Adachi M, et al. Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir. Mol Pharmacol 2007;71:619-27
-
(2007)
Mol Pharmacol
, vol.71
, pp. 619-627
-
-
Imaoka, T.1
Kusuhara, H.2
Adachi, M.3
-
36
-
-
0036186107
-
The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP
-
van Aubel R, Smeets P, Peters J, et al. The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. J Am Soc Nephrol 2002;13:595-603
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 595-603
-
-
Van Aubel, R.1
Smeets, P.2
Peters, J.3
-
37
-
-
66949119640
-
Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: A pharmacogenetic study
-
Rodriguez-Novoa S, Labarga P, Soriano V, et al Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: a pharmacogenetic study. Clin Infect Dis 2009 48 108-16
-
(2009)
Clin Infect Dis
, vol.48
, pp. 108-116
-
-
Rodriguez-Novoa, S.1
Labarga, P.2
Soriano, V.3
-
38
-
-
33845226137
-
Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy
-
Izzedine H, Hulot J, Villard E, et al. Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy. J Infect Dis 2006;194:1481-91
-
(2006)
J Infect Dis
, vol.194
, pp. 1481-1491
-
-
Izzedine, H.1
Hulot, J.2
Villard, E.3
-
39
-
-
79957933957
-
Genetic variants of ABCC10, a novel tenofovir transporter, are associated with kidney tubular dysfunction
-
Pushpakom S, Liptrott N, Rodriguez-Novoa S, et al. Genetic variants of ABCC10, a novel tenofovir transporter, are associated with kidney tubular dysfunction. J Infect Dis 2011;204:145-53
-
(2011)
J Infect Dis
, vol.204
, pp. 145-153
-
-
Pushpakom, S.1
Liptrott, N.2
Rodriguez-Novoa, S.3
-
40
-
-
33745114091
-
Severe liver disease associated with prolonged exposure to antiretroviral rugs
-
Maida I, Nunez M, Rios MJ, et al. Severe liver disease associated with prolonged exposure to antiretroviral rugs. J Acquir Immune Defic Syndr 2006;42:177-82
-
(2006)
J Acquir Immune Defic Syndr
, vol.42
, pp. 177-182
-
-
Maida, I.1
Nunez, M.2
Rios, M.J.3
-
41
-
-
33845945366
-
Nodular regenerative hyperplasia is a new cause of chronic liver disease in HIVinfected patients
-
Mallet V, Blanchard P, Verkarre V, et al. Nodular regenerative hyperplasia is a new cause of chronic liver disease in HIVinfected patients. AIDS 2007;21:187-92
-
(2007)
AIDS
, vol.21
, pp. 187-192
-
-
Mallet, V.1
Blanchard, P.2
Verkarre, V.3
-
42
-
-
67651086987
-
Association of non-cirrhotic portal hypertension in HIV-infected persons and antiretroviral therapy with didanosine: A nested case-control study
-
Kovari H, Ledergerber B, Peter U, et al. Association of non-cirrhotic portal hypertension in HIV-infected persons and antiretroviral therapy with didanosine: a nested case-control study. Clin Infect Dis 2009;49:626-35
-
(2009)
Clin Infect Dis
, vol.49
, pp. 626-635
-
-
Kovari, H.1
Ledergerber, B.2
Peter, U.3
-
43
-
-
84875645759
-
Genetic determinants of idiopathic noncirrhotic portal hypertension in HIVinfected individuals
-
Vispo E, Cevik M, Rockstroh J, et al. Genetic determinants of idiopathic noncirrhotic portal hypertension in HIVinfected individuals. Clin Infect Dis 2013;56:1117-22
-
(2013)
Clin Infect Dis
, vol.56
, pp. 1117-1122
-
-
Vispo, E.1
Cevik, M.2
Rockstroh, J.3
-
44
-
-
0032727054
-
Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitor nevirapine by human hepatic cytochromes P-450
-
Erickson D, Mather G, Trager W, et al. Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitor nevirapine by human hepatic cytochromes P-450. Drug Metab Dispos 1999;27:1488-95
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 1488-1495
-
-
Erickson, D.1
Mather, G.2
Trager, W.3
-
45
-
-
16544365185
-
Genetics of the variable expression of CYP3A in humans
-
Wojnowski L. Genetics of the variable expression of CYP3A in humans. Ther Drug Monit 2004;26:192-9
-
(2004)
Ther Drug Monit
, vol.26
, pp. 192-199
-
-
Wojnowski, L.1
-
46
-
-
0033632228
-
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity
-
Sata F, Sapone A, Elizondo G, et al. CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity. Clin Pharmacol Ther 2000;67:48-56
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 48-56
-
-
Sata, F.1
Sapone, A.2
Elizondo, G.3
-
47
-
-
0000783041
-
Evaluation of the genetic component of variability in CYP3A4 activity: A repeated drug administration method
-
Ozdemir V, Kalowa W, Tang B, et al. Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method. Pharmacogenetics 2000;10:373-88
-
(2000)
Pharmacogenetics
, vol.10
, pp. 373-388
-
-
Ozdemir, V.1
Kalowa, W.2
Tang, B.3
-
48
-
-
20244364148
-
Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients
-
Rotger M, Colombo S, Furrer H, et al. Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients. Pharmacogenet Genomics 2005;15:1-5
-
(2005)
Pharmacogenet Genomics
, vol.15
, pp. 1-5
-
-
Rotger, M.1
Colombo, S.2
Furrer, H.3
-
49
-
-
0037349981
-
Interactions between nevirapine plasma levels, chronic hepatitis C, and the development of liver toxicity in HIV-infected patients
-
Nunez M, Gonzalez de Requena D, Gonzalez-Lahoz J, et al. Interactions between nevirapine plasma levels, chronic hepatitis C, and the development of liver toxicity in HIV-infected patients. AIDS Res Hum Retroviruses 2003;19:187-8
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, pp. 187-188
-
-
Nunez, M.1
Gonzalez De Requena, D.2
Gonzalez-Lahoz, J.3
-
50
-
-
21744442255
-
Changes in nevirapine plasma concentrations over time and its relationship with liver enzyme elevations
-
Gonzalez de Requena D, Jimenez-Nacher I, Soriano V. Changes in nevirapine plasma concentrations over time and its relationship with liver enzyme elevations. AIDS Res Hum Retroviruses 2005;21:555-9
-
(2005)
AIDS Res Hum Retroviruses
, vol.21
, pp. 555-559
-
-
Gonzalez De Requena, D.1
Jimenez-Nacher, I.2
Soriano, V.3
-
51
-
-
65649091303
-
Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African Americans
-
Haas D, Gebretsadik T, Mayo G, et al. Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African Americans. J Infect Dis 2009;199:872-80
-
(2009)
J Infect Dis
, vol.199
, pp. 872-880
-
-
Haas, D.1
Gebretsadik, T.2
Mayo, G.3
-
52
-
-
77957287517
-
CYP2B6 polymorphism and nonnucleoside reverse transcriptase inhibitor plasma concentrations in Chinese HIV-infected patients
-
Chen J, Sun J, Ma Q, et al. CYP2B6 polymorphism and nonnucleoside reverse transcriptase inhibitor plasma concentrations in Chinese HIV-infected patients. Ther Drug Monit 2010;32:573-8
-
(2010)
Ther Drug Monit
, vol.32
, pp. 573-578
-
-
Chen, J.1
Sun, J.2
Ma, Q.3
-
53
-
-
73549123640
-
Nevirapine-induced hepatotoxicity and pharmacogenetics: A retrospective study in a population from Mozambique
-
Ciccacci C, Borgiani P, Ceffa S, et al. Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique. Pharmacogenomics 2010;11:23-31
-
(2010)
Pharmacogenomics
, vol.11
, pp. 23-31
-
-
Ciccacci, C.1
Borgiani, P.2
Ceffa, S.3
-
54
-
-
33748288115
-
Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity
-
Ritchie M, Haas D, Motsinger A, et al. Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity. Clin Infect Dis 2006;43:779-82
-
(2006)
Clin Infect Dis
, vol.43
, pp. 779-782
-
-
Ritchie, M.1
Haas, D.2
Motsinger, A.3
-
55
-
-
37349034567
-
CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children
-
Saitoh A, Sarles E, Capparelli E, et al. CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children. AIDS 2007;21:2191-9
-
(2007)
AIDS
, vol.21
, pp. 2191-2199
-
-
Saitoh, A.1
Sarles, E.2
Capparelli, E.3
-
56
-
-
33847793822
-
Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda
-
Penzak S, Kabuye G, Mugyenyi P, et al. Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda. HIV Med 2007;8:86-91
-
(2007)
HIV Med
, vol.8
, pp. 86-91
-
-
Penzak, S.1
Kabuye, G.2
Mugyenyi, P.3
-
57
-
-
65449118348
-
Cytochrome P450 2B6 516G>T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population
-
Mahungu T, Smith C, Turner F, et al. Cytochrome P450 2B6 516G>T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population. HIV Med 2009;10:310-17
-
(2009)
HIV Med
, vol.10
, pp. 310-317
-
-
Mahungu, T.1
Smith, C.2
Turner, F.3
-
58
-
-
69449103829
-
Risk factors for treatment-limiting toxicities in patients starting nevirapine-containing antiretroviral therapy
-
Kesselring A, Wit F, Sabin C, et al. Risk factors for treatment-limiting toxicities in patients starting nevirapine-containing antiretroviral therapy. AIDS 2009;23:1689-99
-
(2009)
AIDS
, vol.23
, pp. 1689-1699
-
-
Kesselring, A.1
Wit, F.2
Sabin, C.3
-
59
-
-
41549092794
-
Hepatotoxicity of nevirapine in virologically suppressed patients according to gender and CD4 cell counts
-
De Lazzari E, Leon A, Arnaiz J, et al. Hepatotoxicity of nevirapine in virologically suppressed patients according to gender and CD4 cell counts. HIV Med 2008;9:221-6
-
(2008)
HIV Med
, vol.9
, pp. 221-226
-
-
De Lazzari, E.1
Leon, A.2
Arnaiz, J.3
-
60
-
-
39849105346
-
HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz
-
Vitezica Z, Milpied B, Lonjou C, et al. HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz. AIDS 2008;22:540-1
-
(2008)
AIDS
, vol.22
, pp. 540-541
-
-
Vitezica, Z.1
Milpied, B.2
Lonjou, C.3
-
61
-
-
85027929582
-
Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian and European descent
-
Yuan J, Guo S, Hall D, et al. Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian and European descent. AIDS 2011;25:1271-80
-
(2011)
AIDS
, vol.25
, pp. 1271-1280
-
-
Yuan, J.1
Guo, S.2
Hall, D.3
-
62
-
-
33746767604
-
HLA-dependent hypersensitivity to nevirapine in Sardinian HIV patients
-
Littera R, Carcassi C, Masala A, et al. HLA-dependent hypersensitivity to nevirapine in Sardinian HIV patients. AIDS 2006;20:1621-6
-
(2006)
AIDS
, vol.20
, pp. 1621-1626
-
-
Littera, R.1
Carcassi, C.2
Masala, A.3
-
63
-
-
33845945094
-
HLA-Cw8 primarily associated with hypersensitivity to nevirapine
-
Gatanaga H, Yazaki H, Tanuma J, et al. HLA-Cw8 primarily associated with hypersensitivity to nevirapine. AIDS 2007;21:264-5
-
(2007)
AIDS
, vol.21
, pp. 264-265
-
-
Gatanaga, H.1
Yazaki, H.2
Tanuma, J.3
-
64
-
-
84872833727
-
Associations between HLA-DRB1*0102, HLA-B*5801, and hepatotoxicity during initiation of nevirapine-containing regimens in South Africa
-
Phillips E, Bartlett J, Sanne I, et al. Associations between HLA-DRB1*0102, HLA-B*5801, and hepatotoxicity during initiation of nevirapine-containing regimens in South Africa. J Acquir Immune Defic Syndr 2013;62:55-7
-
(2013)
J Acquir Immune Defic Syndr
, vol.62
, pp. 55-57
-
-
Phillips, E.1
Bartlett, J.2
Sanne, I.3
-
65
-
-
79952121425
-
HLA-B*35 is associated with nevirapine hypersensitivity in the contemporary Western Australian HIV cohort study
-
Phillips E, Lucas M, Keane N, et al. HLA-B*35 is associated with nevirapine hypersensitivity in the contemporary Western Australian HIV cohort study. Eur Ann Allergy Clin Immunol 2010;42:48
-
(2010)
Eur Ann Allergy Clin Immunol
, vol.42
, pp. 48
-
-
Phillips, E.1
Lucas, M.2
Keane, N.3
-
66
-
-
59549096348
-
HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients
-
Chantarangsu S, Mushiroda T, Mahasirimongkol S, et al. HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients. Pharmacogenet Genomics 2009;19:139-46
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 139-146
-
-
Chantarangsu, S.1
Mushiroda, T.2
Mahasirimongkol, S.3
-
67
-
-
0035808574
-
Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients
-
Marzolini C, Telenti A, Decosterd L, et al. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients. AIDS 2001;15:71-5
-
(2001)
AIDS
, vol.15
, pp. 71-75
-
-
Marzolini, C.1
Telenti, A.2
Decosterd, L.3
-
68
-
-
1042300270
-
Analyzing sleep abnormalities in HIVinfected patients treated with efavirenz
-
Gallego L, Barreiro P, del Rio R, et al. Analyzing sleep abnormalities in HIVinfected patients treated with efavirenz. Clin Infect Dis 2004;38:430-2
-
(2004)
Clin Infect Dis
, vol.38
, pp. 430-432
-
-
Gallego, L.1
Barreiro, P.2
Del Rio, R.3
-
69
-
-
0038002981
-
The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: Implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity
-
Ward B, Gorski J, Jones D, et al. The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. J Pharmacol Exp Ther 2003;306:287-300
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 287-300
-
-
Ward, B.1
Gorski, J.2
Jones, D.3
-
70
-
-
0034948077
-
Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver
-
Lang T, Klein K, Fischer J, et al. Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver. Pharmacogenetics 2001;11:399-415
-
(2001)
Pharmacogenetics
, vol.11
, pp. 399-415
-
-
Lang, T.1
Klein, K.2
Fischer, J.3
-
71
-
-
0032589627
-
Identification and characterization of efavirenz metabolites by liquid chromatography/mass spectrometry and high field NMR: Species differences in the metabolism of efavirenz
-
Mutlib A, Chen H, Nemeth G, et al. Identification and characterization of efavirenz metabolites by liquid chromatography/mass spectrometry and high field NMR: species differences in the metabolism of efavirenz. Drug Metab Dispos 1999;27:13-33
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 13-33
-
-
Mutlib, A.1
Chen, H.2
Nemeth, G.3
-
72
-
-
70349108450
-
Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine
-
Belanger A, Caron P, Harvey M, et al. Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine. Drug Metab Dispos 2009;37:1793-6
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1793-1796
-
-
Belanger, A.1
Caron, P.2
Harvey, M.3
-
73
-
-
10744221053
-
Hepatic CYP2B6 expression: Gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression
-
Lamba V, Lamba J, Yasuda K, et al. Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression. J Pharmacol Exp Ther 2003;307:906-22
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 906-922
-
-
Lamba, V.1
Lamba, J.2
Yasuda, K.3
-
74
-
-
4644349582
-
Multiple novel non-synonymous CYP2B6 gene polymorphisms in Caucasians: Demonstration of phenotypic null alleles
-
Lang T, Klein K, Richter T, et al. Multiple novel non-synonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles. J Pharmacol Exp Ther 2004;311:34-43
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 34-43
-
-
Lang, T.1
Klein, K.2
Richter, T.3
-
75
-
-
17844375918
-
A natural CYP2B6 TATA box polymorphism (-82T>C) leading to enhanced transcription and relocation of the transcriptional start site
-
Zukunft J, Lang T, Richter T, et al. A natural CYP2B6 TATA box polymorphism (-82T>C) leading to enhanced transcription and relocation of the transcriptional start site. Mol Pharmacol 2005;67:1772-82
-
(2005)
Mol Pharmacol
, Issue.67
, pp. 1772-1782
-
-
Zukunft, J.1
Lang, T.2
Richter, T.3
-
76
-
-
40049092364
-
High prevalence of the CYP2B6 516G>T (*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe
-
Nyakutira C, Roshammar D, Chigutsa E, et al. High prevalence of the CYP2B6 516G>T (*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe. Eur J Clin Pharmacol 2008;64:357-65
-
(2008)
Eur J Clin Pharmacol
, Issue.64
, pp. 357-365
-
-
Nyakutira, C.1
Roshammar, D.2
Chigutsa, E.3
-
77
-
-
34548033928
-
CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: Implications for HIV/AIDS treatment
-
Mehlotra R, Bockarie M, Zimmerman P. CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment. Br J Clin Pharmacol 2007;64:391-5
-
(2007)
Br J Clin Pharmacol
, vol.64
, pp. 391-395
-
-
Mehlotra, R.1
Bockarie, M.2
Zimmerman, P.3
-
78
-
-
2942551228
-
Homozygous CYP2B6*6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz containing regimens
-
Tsuchiya K, Gatanaga H, Tachikawa N, et al. Homozygous CYP2B6*6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz containing regimens. Biochem Biophys Res Commun 2004;319:1322-6
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 1322-1326
-
-
Tsuchiya, K.1
Gatanaga, H.2
Tachikawa, N.3
-
79
-
-
77952322356
-
CYP2B6, CYP2A6 and UGT2B7 polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients
-
Kwara A, Lartey M, Sagoe K, et al. CYP2B6, CYP2A6 and UGT2B7 polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients. AIDS 2009;23:2101-6
-
(2009)
AIDS
, vol.23
, pp. 2101-2106
-
-
Kwara, A.1
Lartey, M.2
Sagoe, K.3
-
80
-
-
80052143211
-
Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: A chargereversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome P450 reductase complex
-
Zhang H, Sridar C, Kenaan C, et al. Polymorphic variants of cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a chargereversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome P450 reductase complex. J Pharmacol Exp Ther 2001;338:803-9
-
(2001)
J Pharmacol Exp Ther
, vol.338
, pp. 803-809
-
-
Zhang, H.1
Sridar, C.2
Kenaan, C.3
-
81
-
-
33947382259
-
Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals
-
Rotger M, Tegude H, Colombo S, et al. Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals. Clin Pharmacol Ther 2007;81:557-66
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 557-566
-
-
Rotger, M.1
Tegude, H.2
Colombo, S.3
-
82
-
-
17644414659
-
Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects
-
Rodriguez-Novoa S, Barreiro P, Rendon A, et al Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects. Clin Infect Dis 2005 40 1358-61
-
(2005)
Clin Infect Dis
, vol.40
, pp. 1358-1361
-
-
Rodriguez-Novoa, S.1
Barreiro, P.2
Rendon, A.3
-
84
-
-
19944428456
-
Pharmacogenetics of efavirenz and central nervous system side effects: An adult ACTG study
-
Haas D, Ribaudo H, Kim R, et al. Pharmacogenetics of efavirenz and central nervous system side effects: an adult ACTG study. AIDS 2004;18:2391-400
-
(2004)
AIDS
, vol.18
, pp. 2391-2400
-
-
Haas, D.1
Ribaudo, H.2
Kim, R.3
-
85
-
-
31044456584
-
Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: An adult ACTG study
-
Ribaudo H, Haas D, Tierney C, et al. Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an adult ACTG study. Clin Infect Dis 2006;42:401-7
-
(2006)
Clin Infect Dis
, vol.42
, pp. 401-407
-
-
Ribaudo, H.1
Haas, D.2
Tierney, C.3
-
86
-
-
34250764311
-
Impact of CYP2B6 polymorphisms on hepatic efavirenz metabolism in vitro
-
Desta Z, Saussele T, Ward B, et al. Impact of CYP2B6 polymorphisms on hepatic efavirenz metabolism in vitro. Pharmacogenomics 2007;8:547-58
-
(2007)
Pharmacogenomics
, vol.8
, pp. 547-558
-
-
Desta, Z.1
Saussele, T.2
Ward, B.3
-
87
-
-
84858674524
-
Associations between ABCB1, CYP2A6, CYP2B6, CYP2D6, and CYP3A5 alleles in relation to efavirenz and nevirapine pharmacokinetics in HIV-infected individuals
-
Heil S, van der Ende M, Schenk P, et al. Associations between ABCB1, CYP2A6, CYP2B6, CYP2D6, and CYP3A5 alleles in relation to efavirenz and nevirapine pharmacokinetics in HIV-infected individuals. Ther Drug Monit 2012;34:153-9
-
(2012)
Ther Drug Monit
, vol.34
, pp. 153-159
-
-
Heil, S.1
Van Der Ende, M.2
Schenk, P.3
-
88
-
-
35348923463
-
Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6*6 and*26
-
Gatanaga H, Hayashida T, Tsuchiya K, et al. Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6*6 and*26. Clin Infect Dis 2007;45:1230-7
-
(2007)
Clin Infect Dis
, vol.45
, pp. 1230-1237
-
-
Gatanaga, H.1
Hayashida, T.2
Tsuchiya, K.3
-
89
-
-
47149109976
-
Successful use of reduced-dose efavirenz in a patient with HIV infection: Case report and review of the literature
-
Torno M, Witt M, Saitoh A, Fletcher C. Successful use of reduced-dose efavirenz in a patient with HIV infection: case report and review of the literature. Pharmacotherapy 2008;28:782-7
-
(2008)
Pharmacotherapy
, vol.28
, pp. 782-787
-
-
Torno, M.1
Witt, M.2
Saitoh, A.3
Fletcher, C.4
-
90
-
-
70449334327
-
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans
-
Mukonzo J, Roshammar D, Waako P, et al. A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans. Br J Clin Pharmacol 2009;68:690-9
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 690-699
-
-
Mukonzo, J.1
Roshammar, D.2
Waako, P.3
-
91
-
-
34648837873
-
Partial deletion of CYP2B6 owing to unequal crossover with CYP2B7
-
Rotger M, Saumoy M, Zhang K, et al. Partial deletion of CYP2B6 owing to unequal crossover with CYP2B7. Pharmacogenet Genomics 2007;17:885-90
-
(2007)
Pharmacogenet Genomics
, vol.17
, pp. 885-890
-
-
Rotger, M.1
Saumoy, M.2
Zhang, K.3
-
92
-
-
77955674979
-
Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort
-
Carr D, la Porte C, Pirmohamed M, et al. Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort. J Antimicrob Chemother 2010;65:1889-93
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 1889-1893
-
-
Carr, D.1
La Porte, C.2
Pirmohamed, M.3
-
93
-
-
80051685348
-
Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens
-
Wyen C, Hendra H, Siccardi M. Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens. J Antimicrob Chemother 2011;66:2092-8
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. 2092-2098
-
-
Wyen, C.1
Hendra, H.2
Siccardi, M.3
-
94
-
-
27944460707
-
Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: An adult ACTG study
-
Haas D, Smeaton L, Shafer R, et al. Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: an adult ACTG study. J Infect Dis 2005;192:1931-42
-
(2005)
J Infect Dis
, vol.192
, pp. 1931-1942
-
-
Haas, D.1
Smeaton, L.2
Shafer, R.3
-
95
-
-
33750312905
-
Multilocus genetic interactions and response to efavirenz-containing regimens: An adult ACTG study
-
Motsinger A, Ritchie M, Shafer R, et al. Multilocus genetic interactions and response to efavirenz-containing regimens: an adult ACTG study. Pharmacogenet Genomics 2006;16:837-45
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 837-845
-
-
Motsinger, A.1
Ritchie, M.2
Shafer, R.3
-
96
-
-
0037022006
-
Response to antiretroviral treatment in HIV-1 infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetic study
-
Fellay J, Marzolini C, Meaden E, et al. Response to antiretroviral treatment in HIV-1 infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetic study. Lancet 2002;259:30-6
-
(2002)
Lancet
, vol.259
, pp. 30-36
-
-
Fellay, J.1
Marzolini, C.2
Meaden, E.3
-
97
-
-
67349205036
-
Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals
-
Arab-Alameddine M, Di Iulio J, Buclin T, et al. Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals. Clin Pharmacol Ther 2009;85:485-94
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 485-494
-
-
Arab-Alameddine, M.1
Di Iulio, J.2
Buclin, T.3
-
98
-
-
63849240305
-
In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function
-
Di Iulio J, Fayet A, Arab-Alameddine M, et al. In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function. Pharmacogenet Genomics 2009;19:300-9
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 300-309
-
-
Di Iulio, J.1
Fayet, A.2
Arab-Alameddine, M.3
-
99
-
-
1642523162
-
Polymorphisms in human MDR1 (Pglycoprotein): Recent advances and clinical relevance
-
Marzolini C, Paus E, Buclin T, et al. Polymorphisms in human MDR1 (Pglycoprotein): recent advances and clinical relevance. Clin Pharmacol Ther 2004;75:13-33
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 13-33
-
-
Marzolini, C.1
Paus, E.2
Buclin, T.3
-
100
-
-
77957145661
-
Influence of host genetics factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients
-
Elens L, Vandercam B, Yombi J, et al. Influence of host genetics factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients. Pharamcogenomics 2010;11:1223-34
-
(2010)
Pharamcogenomics
, vol.11
, pp. 1223-1234
-
-
Elens, L.1
Vandercam, B.2
Yombi, J.3
-
101
-
-
3142751539
-
No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment
-
Winzer R, Langmann P, Zilly M, et al. No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment. Eur J Med Res 2003;8:531-4
-
(2003)
Eur J Med Res
, vol.8
, pp. 531-534
-
-
Winzer, R.1
Langmann, P.2
Zilly, M.3
-
102
-
-
0037462209
-
Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response
-
Brumme Z, Dong W, Chan K, et al. Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response. AIDS 2003;17:201-8
-
(2003)
AIDS
, vol.17
, pp. 201-208
-
-
Brumme, Z.1
Dong, W.2
Chan, K.3
-
103
-
-
15444370017
-
The efavirenz-induced increase in HDL-cholesterol is influenced by the multidrug resistance gene 1 C3435T polymorphism
-
Alonso-Villaverde C, Coll B, Gomez F, et al. The efavirenz-induced increase in HDL-cholesterol is influenced by the multidrug resistance gene 1 C3435T polymorphism. AIDS 2005;19:341-2
-
(2005)
AIDS
, vol.19
, pp. 341-342
-
-
Alonso-Villaverde, C.1
Coll, B.2
Gomez, F.3
-
104
-
-
0042627777
-
The effects of protease inhibitors and non-nucleoside reverse transcriptase inhibitors on P-glycoprotein expression in peripheral blood mononuclear cells in vitro
-
Chandler B, Almond L, Ford J, et al. The effects of protease inhibitors and non-nucleoside reverse transcriptase inhibitors on P-glycoprotein expression in peripheral blood mononuclear cells in vitro. J Acquir Immune Defic Syndr 2003;33:551-6
-
(2003)
J Acquir Immune Defic Syndr
, vol.33
, pp. 551-556
-
-
Chandler, B.1
Almond, L.2
Ford, J.3
-
105
-
-
84871927320
-
Pharmacogenetics-based population pharmacokinetic analysis of etravirine in HIV-1 infected individuals
-
Lubomirov R, Arab-Alameddine M, Rotger M, et al. Pharmacogenetics-based population pharmacokinetic analysis of etravirine in HIV-1 infected individuals. Pharmacogenet Genomics 2013;23:9-18
-
(2013)
Pharmacogenet Genomics
, vol.23
, pp. 9-18
-
-
Lubomirov, R.1
Arab-Alameddine, M.2
Rotger, M.3
-
106
-
-
79959435688
-
Nevirapine versus atazanavir/ritonavir, each combined with tenofovir disoproxil fumarate/emtricitabine, in antiretroviralna? ve HIV-1 patients: The ARTEN trial
-
Soriano V, Arasteh K, Migrone H, et al. Nevirapine versus atazanavir/ritonavir, each combined with tenofovir disoproxil fumarate/emtricitabine, in antiretroviralna? ve HIV-1 patients: the ARTEN trial. Antivir Ther 2011;16:339-48
-
(2011)
Antivir Ther
, vol.16
, pp. 339-348
-
-
Soriano, V.1
Arasteh, K.2
Migrone, H.3
-
107
-
-
33845495422
-
Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia
-
Rodriguez-Novoa S, Martin-Carbonero L, Barreiro P, et al Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia. AIDS 2007 21 41-6
-
(2007)
AIDS
, vol.21
, pp. 41-46
-
-
Rodriguez-Novoa, S.1
Martin-Carbonero, L.2
Barreiro, P.3
-
108
-
-
0033841077
-
Association of human liver bilirubin UDP-glucuronyltransferase activity with a polymorphism in the promoter region of the UGT1A1 gene
-
Raijmakers M, Jansen P, Steegers E, et al. Association of human liver bilirubin UDP-glucuronyltransferase activity with a polymorphism in the promoter region of the UGT1A1 gene. J Hepatol 2000;33:348-51
-
(2000)
J Hepatol
, vol.33
, pp. 348-351
-
-
Raijmakers, M.1
Jansen, P.2
Steegers, E.3
-
109
-
-
48949119333
-
Pharmacogenetics of Gilbert's syndrome
-
Strassburg C. Pharmacogenetics of Gilbert's syndrome. Pharmacogenomics 2008;9:703-15
-
(2008)
Pharmacogenomics
, vol.9
, pp. 703-715
-
-
Strassburg, C.1
-
110
-
-
33751005307
-
Gilbert's disease and atazanavir: From phenotype to UDPglucuronosyltransferase haplotype
-
Lankisch T, Moebius U, Wehmeier M, et al. Gilbert's disease and atazanavir: from phenotype to UDPglucuronosyltransferase haplotype. Hepatology 2006;44:1324-32
-
(2006)
Hepatology
, vol.44
, pp. 1324-1332
-
-
Lankisch, T.1
Moebius, U.2
Wehmeier, M.3
-
111
-
-
25844446183
-
Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia
-
Rotger M, Taffe P, Bleiber G, et al. Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia. J Infect Dis 2005;192:1381-6
-
(2005)
J Infect Dis
, vol.192
, pp. 1381-1386
-
-
Rotger, M.1
Taffe, P.2
Bleiber, G.3
-
112
-
-
77953775606
-
Genetic factors influencing severe atazanavirassociated hyperbilirubinemia in a population with low UDPglucuronosyltransferase 1A1*28 allele frequency
-
Park W, Choe P, Song K, et al. Genetic factors influencing severe atazanavirassociated hyperbilirubinemia in a population with low UDPglucuronosyltransferase 1A1*28 allele frequency. Clin Infect Dis 2010;51:101-6
-
(2010)
Clin Infect Dis
, vol.51
, pp. 101-106
-
-
Park, W.1
Choe, P.2
Song, K.3
-
113
-
-
84865387874
-
Switching to unboosted atazanavir reduces bilirubin and triglycerides without compromising treatment efficacy in UGT1A1*28 polymorphism carriers
-
Ferraris L, Vigano O, Peri A, et al. Switching to unboosted atazanavir reduces bilirubin and triglycerides without compromising treatment efficacy in UGT1A1*28 polymorphism carriers. J Antimicrob Chemother 2012;67:2236-42
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 2236-2242
-
-
Ferraris, L.1
Vigano, O.2
Peri, A.3
-
114
-
-
45749127878
-
Switch from ritonavir boosted atazanavir to unboosted atazanavir guided by therapeutic drug monitoring
-
Rodriguez-Novoa S, Morello J, Barreiro P, et al. Switch from ritonavir boosted atazanavir to unboosted atazanavir guided by therapeutic drug monitoring. AIDS Res Hum Retroviruses 2008;24:821-5
-
(2008)
AIDS Res Hum Retroviruses
, vol.24
, pp. 821-825
-
-
Rodriguez-Novoa, S.1
Morello, J.2
Barreiro, P.3
-
115
-
-
57749095660
-
Population pharmacokinetics of atazanavir in HIV-infected patients
-
Solas C, Gagnieu M, Ravaux I, et al. Population pharmacokinetics of atazanavir in HIV-infected patients. Ther Drug Monit 2008;30:670-3
-
(2008)
Ther Drug Monit
, vol.30
, pp. 670-673
-
-
Solas, C.1
Gagnieu, M.2
Ravaux, I.3
-
116
-
-
7944228403
-
Predictors of virological response to atazanavir in protease inhibitor exposed patients
-
Barrios A, Rendon A, Gallego O, et al. Predictors of virological response to atazanavir in protease inhibitor exposed patients. HIV Clin Trials 2004;5:201-5
-
(2004)
HIV Clin Trials
, vol.5
, pp. 201-205
-
-
Barrios, A.1
Rendon, A.2
Gallego, O.3
-
117
-
-
80053639842
-
Use of serum bilirubin levels as surrogate marker of early virological response to atazanavir-based antiretroviral therapy
-
Morello J, Alvarez E, Cuenca L, et al. Use of serum bilirubin levels as surrogate marker of early virological response to atazanavir-based antiretroviral therapy. AIDS Res Hum Retroviruses 2011;27:1043-5
-
(2011)
AIDS Res Hum Retroviruses
, vol.27
, pp. 1043-1045
-
-
Morello, J.1
Alvarez, E.2
Cuenca, L.3
-
118
-
-
79951801978
-
Detrimental effect of atazanavir plasma concentrations on total serum bilirubin levels in the presence of UGT1A1 polymorphisms
-
Cicconi P, Bini T, Barassi A, et al. Detrimental effect of atazanavir plasma concentrations on total serum bilirubin levels in the presence of UGT1A1 polymorphisms. J Acquir Immune Defic Syndr 2011;56:96-7
-
(2011)
J Acquir Immune Defic Syndr
, vol.56
, pp. 96-97
-
-
Cicconi, P.1
Bini, T.2
Barassi, A.3
-
119
-
-
30144438738
-
Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by 3435C>T polymorphism at the multidrug resistant gene 1
-
Rodriguez-Novoa S, Barreiro P, Rendon A, et al. Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by 3435C>T polymorphism at the multidrug resistant gene 1. Clin Infect Dis 2006;42:291-5
-
(2006)
Clin Infect Dis
, vol.42
, pp. 291-295
-
-
Rodriguez-Novoa, S.1
Barreiro, P.2
Rendon, A.3
-
120
-
-
53349160769
-
Association of a single nucleotide polymorphism in the pregnane X receptor (PXR 63396 C>T) with reduced concentrations of unboosted atazanavir
-
Siccardi M, D'Avolio A, Baietto L, et al. Association of a single nucleotide polymorphism in the pregnane X receptor (PXR 63396 C>T) with reduced concentrations of unboosted atazanavir. Clin Infect Dis 2008;47:1222-5
-
(2008)
Clin Infect Dis
, vol.47
, pp. 1222-1225
-
-
Siccardi, M.1
D'Avolio, A.2
Baietto, L.3
-
121
-
-
78649673343
-
Population pharmacokinetic modeling of the association between 63396 C>T pregnane X receptor polymorphism and unboosted atazanavir clearance
-
Shipani A, Siccardi M, D'Avolio A, et al. Population pharmacokinetic modeling of the association between 63396 C>T pregnane X receptor polymorphism and unboosted atazanavir clearance. Antimicrob Agents Chemother 2010;54:5242-50
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5242-5250
-
-
Shipani, A.1
Siccardi, M.2
D'Avolio, A.3
-
122
-
-
70349213594
-
Efficacy and safety of atazanavir-ritonavir plus abacavir-lamivudine or tenofoviremtricitabine in patients with hyperlipidaemia switched from a stable protease inhibitor-based regimen including one thymidine analogue
-
Calza L, Manfredi R, Colangeli V, et al. Efficacy and safety of atazanavir-ritonavir plus abacavir-lamivudine or tenofoviremtricitabine in patients with hyperlipidaemia switched from a stable protease inhibitor-based regimen including one thymidine analogue. AIDS Patient Care STD 2009;23:691-7
-
(2009)
AIDS Patient Care STD
, vol.23
, pp. 691-697
-
-
Calza, L.1
Manfredi, R.2
Colangeli, V.3
-
123
-
-
84875677476
-
Improved metabolic profile after switch to darunavir/ritonavir in HIV-positive patients previously on protease inhibitor therapy
-
Ucciferri C, Falasca K, Vignale F, et al. Improved metabolic profile after switch to darunavir/ritonavir in HIV-positive patients previously on protease inhibitor therapy. J Med Virol 2013;85:755-9
-
(2013)
J Med Virol
, vol.85
, pp. 755-759
-
-
Ucciferri, C.1
Falasca, K.2
Vignale, F.3
-
124
-
-
84902133793
-
Early lipid changes with atazanavir/ritonavir or darunavir/ritonavir
-
In press
-
Martinez E, Gonzalez-Cordon A, Ferrer E, et al. Early lipid changes with atazanavir/ritonavir or darunavir/ritonavir. HIV Med 2014;In press
-
(2014)
HIV Med
-
-
Martinez, E.1
Gonzalez-Cordon, A.2
Ferrer, E.3
-
125
-
-
84886790685
-
The end of AIDS: HIV infection as a chronic disease
-
Deeks S, Lewin S, Havlir D. The end of AIDS: HIV infection as a chronic disease. Lancet 2013;382:1525-33
-
(2013)
Lancet
, vol.382
, pp. 1525-1533
-
-
Deeks, S.1
Lewin, S.2
Havlir, D.3
-
126
-
-
0024497306
-
Hypertriglyceridemia in the acquired immunodeficiency syndrome
-
Grunfeld C, Kotler D, Hamadeh R, et al. Hypertriglyceridemia in the acquired immunodeficiency syndrome. Am J Med 1989;86:27-31
-
(1989)
Am J Med
, vol.86
, pp. 27-31
-
-
Grunfeld, C.1
Kotler, D.2
Hamadeh, R.3
-
127
-
-
20244375708
-
Modeling the influence of APOC3, APOE and TNF polymorphisms on the risk of antiretroviral therapy associated lipid disorders
-
Tarr P, Taffe P, Bleiber G, et al. Modeling the influence of APOC3, APOE and TNF polymorphisms on the risk of antiretroviral therapy associated lipid disorders. J Infect Dis 2005;191:1419-26
-
(2005)
J Infect Dis
, vol.191
, pp. 1419-1426
-
-
Tarr, P.1
Taffe, P.2
Bleiber, G.3
-
128
-
-
77950344979
-
Dyslipidemia in HIV-infected individuals: From pharmacogenetics to pharmacogenomics
-
Tarr P, Rotger M, Telenti A. Dyslipidemia in HIV-infected individuals: from pharmacogenetics to pharmacogenomics. Pharmacogenomics 2010;11:587-94
-
(2010)
Pharmacogenomics
, vol.11
, pp. 587-594
-
-
Tarr, P.1
Rotger, M.2
Telenti, A.3
-
129
-
-
34547917168
-
Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy
-
Arnedo M, Tarffe P, Sahli R, et al. Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy. Pharmacogenet Genomics 2007;17:755-64
-
(2007)
Pharmacogenet Genomics
, vol.17
, pp. 755-764
-
-
Arnedo, M.1
Tarffe, P.2
Sahli, R.3
-
130
-
-
77449143922
-
Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: A longitudinal study
-
Rotger M, Bayard C, Taffe P, et al. Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study. Circ Cardiovasc Genet 2009;2:621-8
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 621-628
-
-
Rotger, M.1
Bayard, C.2
Taffe, P.3
-
131
-
-
67349217885
-
Pharmacokinetics of raltegravir in individuals with UGT1A1 polymorphisms
-
Wenning L, Petry A, Kost J, et al. Pharmacokinetics of raltegravir in individuals with UGT1A1 polymorphisms. Clin Pharmacol Ther 2009;85:623-7
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 623-627
-
-
Wenning, L.1
Petry, A.2
Kost, J.3
-
132
-
-
84861168106
-
Population pharmacokinetic analysis and pharmacogenetics of raltegravir in HIVpositive and healthy individuals
-
Arab-Alameddine M, Fayet-Mello A, Lubomirov R, et al. Population pharmacokinetic analysis and pharmacogenetics of raltegravir in HIVpositive and healthy individuals. Antimicrob Agents Chemother 2012;56:2959-66
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 2959-2966
-
-
Arab-Alameddine, M.1
Fayet-Mello, A.2
Lubomirov, R.3
-
133
-
-
84892621348
-
Genetic and non-genetic determinants of raltegravir penetration into cerebrospinal fluid: A single arm pharmacokinetic study
-
Johnson D, Sutherland D, Acosta E, et al. Genetic and non-genetic determinants of raltegravir penetration into cerebrospinal fluid: a single arm pharmacokinetic study. PLoS One 2013;8:e82672
-
(2013)
PLoS One
, vol.8
-
-
Johnson, D.1
Sutherland, D.2
Acosta, E.3
-
134
-
-
84890406686
-
High interpatient variability of raltegravir CSF concentrations in HIV-positive patients: A pharmacogenetic analysis
-
Calcagno A, Cusato J, Simiele M, et al. High interpatient variability of raltegravir CSF concentrations in HIV-positive patients: a pharmacogenetic analysis. J Antimicrob Chemother 2014;69:241-5
-
(2014)
J Antimicrob Chemother
, vol.69
, pp. 241-245
-
-
Calcagno, A.1
Cusato, J.2
Simiele, M.3
-
135
-
-
84872696364
-
In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor
-
Reese M, Savina P, Generaux G, et al. In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor. Drug Metab Dispos 2013;41:353-61
-
(2013)
Drug Metab Dispos
, vol.41
, pp. 353-361
-
-
Reese, M.1
Savina, P.2
Generaux, G.3
-
136
-
-
84899457625
-
Dolutegavir, abacavir and lamivudine as HIV therapy
-
Fernandez-Montero JV, Barreiro P, Labarga P, et al. Dolutegavir, abacavir and lamivudine as HIV therapy. Expert Opin Pharmacother 2014;15:1051-7
-
(2014)
Expert Opin Pharmacother
, vol.15
, pp. 1051-1057
-
-
Fernandez-Montero, J.V.1
Barreiro, P.2
Labarga, P.3
-
137
-
-
84884277618
-
Evaluation of the effect of cobicistat on the in vitro renal transport and cytotoxicity potential of tenofovir
-
Stray K, Bam R, Birkus G, et al. Evaluation of the effect of cobicistat on the in vitro renal transport and cytotoxicity potential of tenofovir. Antimicrob Agents Chemother 2013;57:4982-9
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 4982-4989
-
-
Stray, K.1
Bam, R.2
Birkus, G.3
-
138
-
-
84896808364
-
Stribild (elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate): A new paradigm for HIV-1 treatment
-
Manzardo C, Gatell J. Stribild (elvitegravir/cobicistat/emtricitabine/ tenofovir disoproxil fumarate): a new paradigm for HIV-1 treatment. AIDS Rev 2014;16:35-42
-
(2014)
AIDS Rev
, vol.16
, pp. 35-42
-
-
Manzardo, C.1
Gatell, J.2
-
139
-
-
16044373004
-
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson M, Libert F, Dorantz B, et al. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996;382:722-5
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Dorantz, B.3
-
140
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiplyexposed individuals to HIV-1 infection
-
Liu R, Paxton W, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiplyexposed individuals to HIV-1 infection. Cell 1996;86:367-77
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.2
Choe, S.3
-
141
-
-
54849145400
-
Subgroup analysis of maraviroc in previously treated R5 HIV-1 infection
-
Fakenheuer G, Nelson M, Lazzarin A, et al. Subgroup analysis of maraviroc in previously treated R5 HIV-1 infection. N Engl J Med 2008;359:1442-55
-
(2008)
N Engl J Med
, vol.359
, pp. 1442-1455
-
-
Fakenheuer, G.1
Nelson, M.2
Lazzarin, A.3
-
143
-
-
79955768389
-
Pharmacogenetics, pharmacogenomics, and individualized medicine
-
Ma Q, Lu A. Pharmacogenetics, pharmacogenomics, and individualized medicine. Pharmacol Rev 2011;63:437-59
-
(2011)
Pharmacol Rev
, vol.63
, pp. 437-459
-
-
Ma, Q.1
Lu, A.2
-
145
-
-
84860910413
-
The predictive capacity of personal genome sequencing
-
Roberts N, Vogelstein J, Parmigiani G, et al. The predictive capacity of personal genome sequencing. Sci Transl Med 2012;4:133-8
-
(2012)
Sci Transl Med
, vol.4
, pp. 133-138
-
-
Roberts, N.1
Vogelstein, J.2
Parmigiani, G.3
|