Nrf2-mediated HO-1 induction coupled with the ERK signaling pathway contributes to indirect antioxidant capacity of caffeic acid phenethyl ester in HepG2 cells

International Journal of Molecular Sciences

Volumn 15, Issue 7, 2014, Pages 12149-12165

  Kim, Jin Kyoung ^a   Jang, Hae Dong ^a  

^a Hannam University   (South Korea)

Author keywords

(HO 1); (Nrf2) accumulation; Caffeic acid phenethyl ester (CAPE); ERK (extracellular signal regulated kinase) phosphorylation; Heme oxygenase; Indirect antioxidant activity; Nuclear transcription factor erythroid 2 related factor

Indexed keywords

CAFFEIC ACID PHENETHYL ESTER; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; CAFFEIC ACID DERIVATIVE; HEME OXYGENASE 1; NFE2L2 PROTEIN, HUMAN; PHENETHYL ALCOHOL;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DETOXIFICATION; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; LUCIFERASE ASSAY; MTT ASSAY; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; DRUG EFFECTS; GENETICS; HEPG2 CELL LINE; METABOLISM;

ANTIOXIDANTS; CAFFEIC ACIDS; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHENYLETHYL ALCOHOL;

EID: 84904158905     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150712149     Document Type: Article

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