Establishment of a pancreatic β cell proliferation model in vitro and a platform for diabetes drug screening

Cytotechnology

Volumn 66, Issue 4, 2014, Pages 687-697

  Jia, Jing ^a   Liu, Xiaoli ^b   Chen, Yongxia ^c   Zheng, Xiaoliang ^a   Tu, Linglan ^a   Huang, Xiaoming ^a   Wang, Xiaoju ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b ZHEJIANG HOSPITAL   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Drug screen; Islet neogenesis; Pancreatic cell; Proliferation model

Indexed keywords

CYTOKERATIN; DITHIZONE; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MESSENGER RNA; PAN CYTOKERATIN; PROPIDIUM IODIDE; PROTEIN; REGENERATING GENE IALPHA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; APOPTOSIS ASSAY; ARTICLE; BIOLOGICAL ACTIVITY; CELL DENSITY; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CELL SUSPENSION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG SCREENING; EPITHELIUM CELL; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALE; MOLECULAR WEIGHT; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING;

RATTUS; RATTUS NORVEGICUS;

EID: 84904114614     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-013-9622-y     Document Type: Article

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