Islet transplantation in type I diabetes mellitus

Yale Journal of Biology and Medicine

Volumn 85, Issue 1, 2012, Pages 37-43

  Jamiolkowski, Ryan M ^a   Guo, Lucie Y ^a   Li, Yun Rose ^a   Shaffer, Sydney M ^a   Naji, Ali ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cell therapy; Diabetes; Immunosuppression; Islet transplantation; Pancreas

Indexed keywords

CORTICOSTEROID; DACLIZUMAB; ETANERCEPT; GLUCOSE; HEMOGLOBIN A1C; IMMUNOSUPPRESSIVE AGENT; INSULIN; RAPAMYCIN; TACROLIMUS; THYMOCYTE ANTIBODY;

ARTICLE; BLOOD GLUCOSE MONITORING; CADAVER DONOR; CLINICAL PROTOCOL; CLINICAL TRIAL (TOPIC); GLYCEMIC CONTROL; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; HYPOGLYCEMIA; IMMUNOSUPPRESSIVE TREATMENT; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; KIDNEY DISEASE; MEDICAL RESEARCH; MOUTH ULCER; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PANCREAS TRANSPLANTATION; RECURRENCE RISK; RISK ASSESSMENT; STEM CELL TRANSPLANTATION; SURGICAL RISK;

ANIMALS; DIABETES MELLITUS, TYPE 1; HUMANS; INSULIN; ISLETS OF LANGERHANS TRANSPLANTATION; PANCREAS TRANSPLANTATION;

EID: 84859310580     PISSN: 00440086     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Cryer PE, Davis SN, Shamoon H. Hypoglycemia in diabetes. Diabetes Care. 2003;26(6):1902-12.
2. Zeng Y, Ricordi C, Lendoire J, Carroll PB, Alejandro R, Bereiter DR, et al. The effect of prednisone on pancreatic islet autografts in dogs. Surgery. 1993;113(1):98-102.
3. Eisenbarth GS. Type I diabetes mellitus. A chronic autoimmune disease. New Engl J Med. 1986;314(21):1360-8.
4. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus. New Engl J Med. 1993;329(14):977-86.
5. Krinsley JS, Schultz MJ, Spronk PE, Harmsen RE, van Braam Houckgeest F, van der Sluijs JP, et al. Mild hypoglycemia is independently associated with increased mortality in the critically ill. Crit Care. 2011;15(4):R173.
6. Zinman B, Fulcher G, Rao PV, Thomas N, Endahl LA, Johansen T, et al. Insulin degludec, an ultra-long-acting basal insulin, once a day or three times a week versus insulin glargine once a day in patients with type 2 diabetes: a 16-week, randomised, open-label, phase 2 trial. Lancet. 2011;377(9769):924-31.
7. Cryer PE. Mechanisms of Hypoglycemia-Associated Autonomic Failure and Its Component Syndromes in Diabetes. Diabetes. 2005;54(12):3592-601.
8. Cryer PE. The barrier of hypoglycemia in diabetes. Diabetes. 2008;57(12):3169-76.
9. Ragnar H. Dead-in-bed syndrome in diabetes mellitus and hypoglycaemic unawareness. Lancet. 1997;350(9076):492-3.
10. McCrimmon RJ, Sherwin RS. Hypoglycemia in type 1 diabetes. Diabetes. 2010;59(10):2333-9.
11. Kelly WD, Lillehei RC, Merkel FK, Idezuki Y, Goetz FC. Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy. Surgery. 1967;61(6):827-37.
12. Nathan DM. Isolated Pancreas Transplantation for Type 1 Diabetes. JAMA. 2003;290(21):2861-3.
13. Venstrom JM, McBride MA, Rother KI, Hirshberg B, Orchard TJ, Harlan DM. Survival After Pancreas Transplantation in Patients With Diabetes and Preserved Kidney Function. JAMA. 2003;290(21):2817-23.
14. Lifetime Benefits and Costs of Intensive Therapy as Practiced in the Diabetes Control and Complications Trial. JAMA. 1996;276(17):1409-15.
15. Pancreas Transplantation in Type 1 Diabetes. Diabetes Care. 2004;27(Suppl 1):s105.
16. Browne S, Gill J, Dong J, Rose C, Johnston O, Zhang P, et al. The Impact of Pancreas Transplantation on Kidney Allograft Survival. Am J Transplant. 2011;11(9):1951-8.
17. Gruessner RWG, Sutherland DER, Gruessner AC. Mortality Assessment for Pancreas Transplants. Am J Transplant. 2004;4(12):2018-26.
18. Ballinger WF, Lacy PE. Transplantation of intact pancreatic islets in rats. Surgery. 1972;72(2):175-86.
19. Reckard CR, Barker CF. Transplantation of isolated pancreatic islets across strong and weak histocompatibility barriers. Transplant Proc. 1973;5(1):761-3.
20. Kemp CB, Knight MJ, Scharp DW, Lacy PE, Ballinger WF. Transplantation of isolated pancreatic islets into the portal vein of diabetic rats. Nature. 1973;244(5416):447.
21. Ricordi C, Lacy PE, Finke EH, Olack BJ, Scharp DW. Automated method for isolation of human pancreatic islets. Diabetes. 1988;37(4):413-20.
22. Sá JR, Gonzalez AM, Melaragno CS, Saitovich D, Franco DR, Rangel EB, et al. Transplante de pâncreas e ilhotas em portadores de diabetes melito. Arquivos Brasileiros de Endocrinologia & Metabologia. 2008;52:355-66.
23. Rother KI, Harlan DM. Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus. J Clin Invest. 2004;114(7):877-83.
24. Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. New Engl J Med. 2000;343(4):230-8.
25. Ryan EA, Paty BW, Senior PA, Bigam D, Alfadhli E, Kneteman NM, et al. Five-Year Follow-Up After Clinical Islet Transplantation. Diabetes. 2005;54(7):2060-9.
26. Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, et al. International trial of the Edmonton protocol for islet transplantation. New Engl J Med. 2006;355(13):1318-30.
27. Bromberg JS, Kaplan B, Halloran PF, Robertson RP. The islet transplant experiment: time for a reassessment. Am J Transplant. 2007;7(10):2217-8.
28. Ruggenenti P, Remuzzi A, Remuzzi G. Decision time for pancreatic islet-cell transplantation. Lancet. 2008;371(9616):883-4.
29. Campbell PM, Senior PA, Salam A, Labranche K, Bigam DL, Kneteman NM, et al. High risk of sensitization after failed islet transplantation. Am J Transplant. 2007;7(10):2311-7.
30. Shapiro AM. Islet transplantation-the imperative need for continued clinical trials. Nat Clin Pract Nephrol. 2008;4(12):662-3.
31. Hering BJ, Kandaswamy R, Ansite JD, Eckman PM, Nakano M, Sawada T, et al. Single-Donor, Marginal-Dose Islet Transplantation in Patients With Type 1 Diabetes. JAMA. 2005;293(7):830-5.
32. Bonnefoy-Berard N, Fournel S, Genestier L, Flacher M, Quemeneur L, Revillard JP. In vitro functional properties of antithymocyte globulins: clues for new therapeutic applications? Transplant Proc. 1998;30(8):4015-7.
33. Farney AC, Xenos E, Sutherland DE, Widmer M, Stephanian E, Field MJ, et al. Inhibition of pancreatic islet beta cell function by tumor necrosis factor is blocked by a soluble tumor necrosis factor receptor. Transplant Proc. 1993;25(1 Pt 2):865-6.
34. Hering BJ, Kandaswamy R, Harmon JV, Ansite JD, Clemmings SM, Sakai T, et al. Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody. Am J Transplant. 2004;4(3):390-401.
35. Executive summary: Standards of medical care in diabetes-2010. Diabetes Care. 2010;33(Suppl 1):S4-10.
36. Chen S, Borowiak M, Fox JL, Maehr R, Osafune K, Davidow L, et al. A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat Chem Biol. 2009;5(4):258-65.
37. Bonner-Weir S, Taneja M, Weir GC, Tatarkiewicz K, Song K-H, Sharma A, et al. In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci USA. 2000;97(14):7999-8004.
38. Nagaya M, Katsuta H, Kaneto H, Bonner-Weir S, Weir GC. Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells. J Endocrinol. 2009;201(1):37-47.
39. Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to [bgr]-cells. Nature. 2008;455(7213):627-32.
40. Aviv V, Meivar-Levy I, Rachmut IH, Rubinek T, Mor E, Ferber S. Exendin-4 Promotes Liver Cell Proliferation and Enhances the PDX-1-induced Liver to Pancreas Transdifferentiation Process. J Biol Chem. 2009;284(48):33509-20.
41. Tateishi K, He J, Taranova O, Liang G, D'Alessio AC, Zhang Y. Generation of Insulin-secreting Islet-like Clusters from Human Skin Fibroblasts. J Biol Chem. 2008;283(46):31601-7.
42. Hering BJ, Wijkstrom M, Graham ML, Hardstedt M, Aasheim TC, Jie T, et al. Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates. Nat Med. 2006;12(3):301-3.
43. O'Sullivan ES, Vegas A, Anderson DG, Weir GC. Islets Transplanted in Immunoisolation Devices: A Review of the Progress and the Challenges that Remain. Endocr Rev. 2011;32(6):827-44.
44. Liu C, Noorchashm H, Sutter JA, Naji M, Prak EL, Boyer J, et al. B lymphocyte-directed immunotherapy promotes long-term islet allograft survival in nonhuman primates. Nat Med. 2007;13(11):1295-8.