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Volumn 20, Issue 2, 2011, Pages 223-232

Betacellulin overexpression in mesenchymal stem cells induces insulin secretion in vitro and ameliorates streptozotocin-induced hyperglycemia in rats

Author keywords

[No Author keywords available]

Indexed keywords

BETACELLULIN; INSULIN; NICOTINAMIDE;

EID: 78951480382     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2009.0490     Document Type: Article
Times cited : (36)

References (48)
  • 1
    • 34447100368 scopus 로고    scopus 로고
    • Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1
    • Chen S, J Ding, C Yu, B Yang, DR Wood and PA Grayburn. (2007). Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1. Gene Ther 14:1102-1110.
    • (2007) Gene Ther , vol.14 , pp. 1102-1110
    • Chen, S.1    Ding, J.2    Yu, C.3    Yang, B.4    Wood, D.R.5    Grayburn, P.A.6
  • 2
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mel-litus using a glucocorticoid-free immunosuppressive regi-men
    • Shapiro AM, JR Lakey, EA Ryan, GS Korbutt, E Toth, GL Warnock, NM Kneteman and RV Rajotte. (2000). Islet transplantation in seven patients with type 1 diabetes mel-litus using a glucocorticoid-free immunosuppressive regi-men. N Engl J Med 343:230-238.
    • (2000) N Engl J Med , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3    Korbutt, G.S.4    Toth, E.5    Warnock, G.L.6    Kneteman, N.M.7    Rajotte, R.V.8
  • 3
    • 19544386310 scopus 로고    scopus 로고
    • Teratoma formation leads to failure of treatment for type 1 diabetes using embryonic stem cell-derived insulin producing cells
    • Fujiwaka T, SH Oh, LE Pi, HM Hatch, T Shuope and BE Petersen. (2005). Teratoma formation leads to failure of treatment for type 1 diabetes using embryonic stem cell-derived insulin producing cells. Am J Pathol166:1781-1791.
    • (2005) Am J Pathol , vol.166 , pp. 1781-1791
    • Fujiwaka, T.1    Oh, S.H.2    Pi, L.E.3    Hatch, H.M.4    Shuope, T.5    Petersen, B.E.6
  • 5
    • 20444406125 scopus 로고    scopus 로고
    • In vitro transdifferentiation of hepatoma cells into functional pan-creatic cells
    • Li WC, ME Horb, D Tosh and JM Slack. (2005). In vitro transdifferentiation of hepatoma cells into functional pan-creatic cells. Mech Dev 122:835-847.
    • (2005) Mech Dev , vol.122 , pp. 835-847
    • Li, W.C.1    Horb, M.E.2    Tosh, D.3    Slack, J.M.4
  • 6
    • 0037062515 scopus 로고    scopus 로고
    • In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells
    • Yang L, S Li, H Hatch, K Ahrens, JG Cornelius, PE Petersen and AB Peck. (2002). In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells. Proc Natl Acad Sci USA 99:8078-8083.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8078-8083
    • Yang, L.1    Li, S.2    Hatch, H.3    Ahrens, K.4    Cornelius, J.G.5    Petersen, P.E.6    Peck, A.B.7
  • 9
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
    • Ramiya VK, M Maraist, KE Arfors, DA Schatz, AB Peck and JG Cornelius. (2000). Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat Med 6:278-282.
    • (2000) Nat Med , vol.6 , pp. 278-282
    • Ramiya, V.K.1    Maraist, M.2    Arfors, K.E.3    Schatz, D.A.4    Peck, A.B.5    Cornelius, J.G.6
  • 12
    • 0344961120 scopus 로고    scopus 로고
    • Murine marrow-derived mesenchymal stem cell: Isolation, in vitro expansion and characterization
    • Meirelles LS and NB Nardi. (2003). Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion and characterization. Br J Haematol 123:702-711.
    • (2003) Br J Haematol , vol.123 , pp. 702-711
    • Meirelles, L.S.1    Nardi, N.B.2
  • 14
    • 51849144706 scopus 로고    scopus 로고
    • Coexpression of Pdx1 and betacellulin in mesenchy-mal stem cells could promote the differentiation of nestin-positive ephitelim-like progenitors and pancreatic islet-like spheroids
    • Li L, L Furong, H Qi, G Feng, K Yuan, H Deng and H Zhou. (2008). Coexpression of Pdx1 and betacellulin in mesenchy-mal stem cells could promote the differentiation of nestin-positive ephitelim-like progenitors and pancreatic islet-like spheroids. Stem Cells Dev 17:815-823.
    • (2008) Stem Cells Dev , vol.17 , pp. 815-823
    • Li, L.1    Furong, L.2    Qi, H.3    Feng, G.4    Yuan, K.5    Deng, H.6    Zhou, H.7
  • 15
    • 36248934727 scopus 로고    scopus 로고
    • Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation
    • Karnieli O, Y Izhar-Prato, S Bulvik and S Efrat. (2007). Generation of insulin-producing cells from human bone marrow mesenchymal stem cells by genetic manipulation. Stem Cells 25:2837-2844.
    • (2007) Stem Cells , vol.25 , pp. 2837-2844
    • Karnieli, O.1    Izhar-Prato, Y.2    Bulvik, S.3    Efrat, S.4
  • 16
    • 37349097054 scopus 로고    scopus 로고
    • Human islet-derived precursor cells are mesenchymal stro-mal cells that differentiate and mature hormone-expressing cells in vivo
    • Davani B, L Ikonomou, BM Raaka, E Geras-Raaka, RA Morton, B Marcus-Samuels and MC Gershengon. (2007). Human islet-derived precursor cells are mesenchymal stro-mal cells that differentiate and mature hormone-expressing cells in vivo. Stem Cells 25:3215-3222.
    • (2007) Stem Cells , vol.25 , pp. 3215-3222
    • Davani, B.1    Ikonomou, L.2    Raaka, B.M.3    Geras-Raaka, E.4    Morton, R.A.5    Marcus-Samuels, B.6    Gershengon, M.C.7
  • 17
    • 58149376976 scopus 로고    scopus 로고
    • The epidermal growth factor receptor ligands at a glance
    • Schneider MR and E Wolf. (2009). The epidermal growth factor receptor ligands at a glance. J Cell Physiol 218: 460-466.
    • (2009) J Cell Physiol , vol.218 , pp. 460-466
    • Schneider, M.R.1    Wolf, E.2
  • 21
    • 0033762832 scopus 로고    scopus 로고
    • A role for activin and betacellulin in human fetal pancreatic cell differentiation and grothw
    • Detemerco C, GM Beattie, SA Dib, AD Lopez and A Hayek. (2000). A role for activin and betacellulin in human fetal pancreatic cell differentiation and grothw. J Clin Endocrinol Metab 85:3892-3897.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3892-3897
    • Detemerco, C.1    Beattie, G.M.2    Dib, S.A.3    Lopez, A.D.4    Hayek, A.5
  • 22
    • 0041965739 scopus 로고    scopus 로고
    • Betacellulin improves glucose metabolism by promoting conversion of intraislet precursor p-cells in streptozotocin-treated mice
    • Li L, M Seno, H Yamada and I Kojima. (2003). Betacellulin improves glucose metabolism by promoting conversion of intraislet precursor p-cells in streptozotocin-treated mice. Am J Physiol Endocrinol Metab 285:E577-E583.
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Li, L.1    Seno, M.2    Yamada, H.3    Kojima, I.4
  • 25
    • 1442276960 scopus 로고    scopus 로고
    • Activin A and Betacellulin: Effect on regeneration of pancreatic beta-cells in neonatal steptozotocin-treated rats
    • Li L, Z Yi, M Seno and I Kojima. (2004). Activin A and Betacellulin: effect on regeneration of pancreatic beta-cells in neonatal steptozotocin- treated rats. Diabetes 53:608-615.
    • (2004) Diabetes , vol.53 , pp. 608-615
    • Li, L.1    Yi, Z.2    Seno, M.3    Kojima, I.4
  • 26
    • 27844462457 scopus 로고    scopus 로고
    • Beta-cellulin overexpression in transgenic mice causes dispro-portionate growth, pulmonary hemorrhage syndrome, and complex eye pathology
    • Schneider MR, M Dahlhoff, N Herbah, I Renner-Mueller, C Dalke, O Puk, J Graw, R Wanke and E Wolf. (2005). Beta-cellulin overexpression in transgenic mice causes dispro-portionate growth, pulmonary hemorrhage syndrome, and complex eye pathology. Endocrinology 146:5237-5246.
    • (2005) Endocrinology , vol.146 , pp. 5237-5246
    • Schneider, M.R.1    Dahlhoff, M.2    Herbah, N.3    Renner-Mueller, I.4    Dalke, C.5    Puk, O.6    Graw, J.7    Wanke, R.8    Wolf, E.9
  • 28
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • Lumelsky N, O Blondel, P Laeng, I Velasco, R Ravin and R Mckay. (2001). Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Sci-ence 292:1389-1394.
    • (2001) Science , vol.292 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    McKay, R.6
  • 29
    • 69249196200 scopus 로고    scopus 로고
    • Generation of pancreatic hormone-expressing islet-like cell aggregates from murine adipose tissue-derived stem cells
    • Chandra V, G Swetha, S Phadnis, PD Nair and RR Bhonde. (2009). Generation of pancreatic hormone-expressing islet-like cell aggregates from murine adipose tissue-derived stem cells. Stem Cells 27:1941-1953.
    • (2009) Stem Cells , vol.27 , pp. 1941-1953
    • Chandra, V.1    Swetha, G.2    Phadnis, S.3    Nair, P.D.4    Bhonde, R.R.5
  • 30
    • 50949121532 scopus 로고    scopus 로고
    • In vitro cultivation of islet-like cell clusters from human umbilical cord blood-derived mesenchymal stem cells
    • Gao F, DQ Wu, YH Hu, GX Jin, GD Li, TW Sun and FJ Li. (2008). In vitro cultivation of islet-like cell clusters from human umbilical cord blood-derived mesenchymal stem cells. Transl Res 151:293-302.
    • (2008) Transl Res , vol.151 , pp. 293-302
    • Gao, F.1    Wu, D.Q.2    Hu, Y.H.3    Jin, G.X.4    Li, G.D.5    Sun, T.W.6    Li, F.J.7
  • 31
    • 17044401306 scopus 로고    scopus 로고
    • In vitro trans-differentiation of rat Mesenchymal stem cells into insulin-producing cells by rat pancreatic extract
    • Choi KS, JS Shin, JJ Lee, SB Kim and CW Kim. (2005). In vitro trans-differentiation of rat Mesenchymal stem cells into insulin-producing cells by rat pancreatic extract. Biochem Biophys Res Commun 330:1299-1305.
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 1299-1305
    • Choi, K.S.1    Shin, J.S.2    Lee, J.J.3    Kim, S.B.4    Kim, C.W.5
  • 32
    • 13744261497 scopus 로고    scopus 로고
    • Regeneration of pancreatic p cell
    • Trucco M. (2005). Regeneration of pancreatic p cell. J Clin Invest 115:5-12.
    • (2005) J Clin Invest , vol.115 , pp. 5-12
    • Trucco, M.1
  • 33
    • 0031763478 scopus 로고    scopus 로고
    • Growth factor-mediated proliferation and differentiation of insulin-producing INS-1 and RINm5F cells: Identification of betacellulin as a novel beta-cell mitogen
    • Huotari MA, J Palgi and T Otonkoski. (1998). Growth factor-mediated proliferation and differentiation of insulin-producing INS-1 and RINm5F cells: identification of betacellulin as a novel beta-cell mitogen. Endocrinology 139:1494-1499.
    • (1998) Endocrinology , vol.139 , pp. 1494-1499
    • Huotari, M.A.1    Palgi, J.2    Otonkoski, T.3
  • 34
    • 58949095742 scopus 로고    scopus 로고
    • Beta-cellulin overexpression in transgenic mice improves glucose tolerance and enhances insulin secretion by isolated islets in vitro
    • Dahlhoff M, PM Dames, A Leechner, N Herbach, L van Burck, R Wanke, E Wolf and MR Schneider. (2009). Beta-cellulin overexpression in transgenic mice improves glucose tolerance and enhances insulin secretion by isolated islets in vitro. Mol Cell Endocrinol 299:188-193.
    • (2009) Mol Cell Endocrinol , vol.299 , pp. 188-193
    • Dahlhoff, M.1    Dames, P.M.2    Leechner, A.3    Herbach, N.4    Van Burck, L.5    Wanke, R.6    Wolf, E.7    Schneider, M.R.8
  • 36
    • 16444363423 scopus 로고    scopus 로고
    • Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas de-velopmental pathway upon genetic and/or microenviron-mental manipulation in vitro
    • Moriscot C, F Fraipont, MJ Richard, M Marchand, P Sa-vatier, D Bosco, M Fravot and PY Benhamou. (2005). Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine pancreas de-velopmental pathway upon genetic and/or microenviron-mental manipulation in vitro. Stem Cells 23:594-604.
    • (2005) Stem Cells , vol.23 , pp. 594-604
    • Moriscot, C.1    Fraipont, F.2    Richard, M.J.3    Marchand, M.4    Sa-Vatier, P.5    Bosco, D.6    Fravot, M.7    Benhamou, P.Y.8
  • 38
    • 68149156892 scopus 로고    scopus 로고
    • Ephitelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells
    • Russ HA, P Ravassard, J Kerr-Conte, F Pattou and S Efrat. (2009). Ephitelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells. Plos One 4:e6417.
    • (2009) Plos One , vol.4
    • Russ, H.A.1    Ravassard, P.2    Kerr-Conte, J.3    Pattou, F.4    Efrat, S.5
  • 39
    • 33847357833 scopus 로고    scopus 로고
    • No evidence for mouse pancreatic B-cell epithelial to mesenchymal transition in vitro
    • Atouf F, CH Park, K Pechhold, M Ta, Y Choi and NL Lu-melsky. (2007). No evidence for mouse pancreatic B-cell epithelial to mesenchymal transition in vitro. Diabetes 56: 699-702.
    • (2007) Diabetes , vol.56 , pp. 699-702
    • Atouf, F.1    Park, C.H.2    Pechhold, K.3    Ta, M.4    Choi, Y.5    Lu-Melsky, N.L.6
  • 40
    • 0025869971 scopus 로고
    • Effects of poly (ADP-ribose) synthetase inhibitor on B-cells of a canine pancreas alter massive pancreatectomy
    • Sugiyama K, H Yonemura and H Okamoto. (1991). Effects of poly (ADP-ribose) synthetase inhibitor on B-cells of a canine pancreas alter massive pancreatectomy. Int J Pancreatol 8:85-95.
    • (1991) Int J Pancreatol , vol.8 , pp. 85-95
    • Sugiyama, K.1    Yonemura, H.2    Okamoto, H.3
  • 41
    • 0027265403 scopus 로고
    • Nicotinamide is a potent inducer of endocrine dif-ferentiation in cultured human fetal pancreatic cells
    • Otonkoski T, GM Beattie, MI Mally, C Ricordi and A Hayek. (1993). Nicotinamide is a potent inducer of endocrine dif-ferentiation in cultured human fetal pancreatic cells. J Clin Invest 92:1459-1466.
    • (1993) J Clin Invest , vol.92 , pp. 1459-1466
    • Otonkoski, T.1    Beattie, G.M.2    Mally, M.I.3    Ricordi, C.4    Hayek, A.5
  • 44
    • 46749115173 scopus 로고    scopus 로고
    • A simple method to induce differentiation of murine bone marrow mesenchymal stem cells to insulin-producing Con-ophylline and betacellulin-delta4
    • Hisanaga E, KI Park, S Yamada, H Hashimoto, T Takeuchi, M Mori, M Seno, K Umezawa, I Takei and I Kojima. (2008). A simple method to induce differentiation of murine bone marrow mesenchymal stem cells to insulin-producing Con-ophylline and betacellulin-delta4. Endrocr J 55:535-543.
    • (2008) Endrocr J , vol.55 , pp. 535-543
    • Hisanaga, E.1    Park, K.I.2    Yamada, S.3    Hashimoto, H.4    Takeuchi, T.5    Mori, M.6    Seno, M.7    Umezawa, K.8    Takei, I.9    Kojima, I.10
  • 46
    • 33644781780 scopus 로고    scopus 로고
    • Angio-tensin II type 1 receptor blockade improves beta-cell func-tion and glucose tolerance in a mouse model of type 2 diabetes
    • Chu KY, T Lau, PO Carlsson and PS Leung. (2006). Angio-tensin II type 1 receptor blockade improves beta-cell func-tion and glucose tolerance in a mouse model of type 2 diabetes. Diabetes 55:367-374.
    • (2006) Diabetes , vol.55 , pp. 367-374
    • Chu, K.Y.1    Lau, T.2    Carlsson, P.O.3    Leung, P.S.4
  • 47
    • 1542374750 scopus 로고    scopus 로고
    • Evidence for local angiotensin-generating system and dose-dependent inhibi-tion of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets
    • Lau T, PO Carlsson and PS Leung. (2004). Evidence for local angiotensin-generating system and dose-dependent inhibi-tion of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. Diabetologia 47:240-248.
    • (2004) Diabetologia , vol.47 , pp. 240-248
    • Lau, T.1    Carlsson, P.O.2    Leung, P.S.3
  • 48
    • 70349235406 scopus 로고    scopus 로고
    • Regenerative medicine for diabetes mellitus
    • Kobayashi N, T Yuasa and T Okitsu. (2009). Regenerative medicine for diabetes mellitus. Cell Transplant 18:491-496.
    • (2009) Cell Transplant , vol.18 , pp. 491-496
    • Kobayashi, N.1    Yuasa, T.2    Okitsu, T.3


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