Paclitaxel up-regulates interleukin-8 synthesis in human lung carcinoma through an NF-κB- and AP-1-dependent mechanism

Cancer Immunology Immunotherapy

Volumn 49, Issue 2, 2000, Pages 78-84

  Collins, Timothy S ^a   Lee, Li Fen ^b,c   Ting, Jenny P Y ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chemokines; Lung; Signal transduction; Transcription factors

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; DACTINOMYCIN; DIMETHYL SULFOXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PACLITAXEL; RECOMBINANT INTERLEUKIN 8; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; LUNG CARCINOMA; PATIENT SELECTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; UNITED STATES;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, NON-SMALL-CELL LUNG; HUMANS; INTERLEUKIN-8; LUNG NEOPLASMS; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PACLITAXEL; TRANSCRIPTION FACTOR AP-1; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0033920205     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050605     Document Type: Article

References (28)

1. 1. Arenberg DA, Kunkel SL, Polverini PJ, Glass M, Burdick MD, Strieter RM (1996) Inhibition of interleukin-8 reduces tumorigenicity of human non-small cell lung cancer in SCID mice. J Clin Invest 97: 2792
2. 2. Baggiolini M, Walz A, Kunkel SL (1989) Neutrophil-activating peptide-I/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest 84: 1045
3. 3. Baldwin AS Jr (1996) The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 14: 649-83: 649
4. 4. Bogdan C, Ding A (1992) Taxol, a microtubule-stabilizing antineoplastic agent, induces expression of tumor necrosis factor alpha and interleukin-1 in macrophages. J Leukoc Biol 52: 119
5. 5. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18: 5294
6. 6. Das KC, White CW (1997) Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C J Biol Chem 272: 14914
7. 7. Ding AH, Porteu F, Sanchez E, Nathan CF (1990) Shared actions of endotoxin and taxol on TNF receptors and TNF release. Science 248: 370
8. 8. Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623
9. 9. Goldspiel BR (1997) Clinical overview of the taxanes. Pharmacol Ther 5: 110S
10. 10. Hirose K, Hakozaki M, Nyunoya Y, Kobayashi Y (1995) Chemokine gene expression transfection into tumor cells reduced tumorigenicity in nude mice in association with neutrophilic infiltration. Br J Cancer 72: 708
11. 11. Johnson DH, Chang AY, Ettinger DS, Kim KM, Bonomi P (1998) Recent advances with chemotherapy for NSCLC: the ECOG experience. Eastern Cooperative Oncology Group. Oncology (Huntingt) 12: 67
12. 12. Lee L-F, Lofquist AK, Schurer-Maly CC, Day C, Ting JPY, White CM, Martin BK, Haskill JS (1996) Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer. Cancer Res 56: 1303
13. 13. Lee L-F, Haskill JS, Mukaida N, Matsushima K, Ting JPY (1997) Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter. Mol Cell Biol 17: 5097
14. 14. Lee LF, Li G, Templeton DJ, Ting JP (1998) Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK). J Biol Chem 273: 28253
15. 15. Lee L-F, Hellendall RP, Wang Y, Haskill JS, Mukaida N, Matsushima K, Ting JPY (1999) IL-8 reduced tumorigenicity of human ovarian cancer in vivo due to neutrophil infiltration (in press)
16. 16. Manthey CL, Brandes ME, Perera PY, Vogel SN (1992) Taxol increases steady-state levels of lipopolysaccharide-inducible genes and protein-tyrosine phosphorylation in murine macrophages. J Immunol 149: 2459
17. 17. Martini N, Ginsberg RJ (1996) Treatment of stage I and II disease. In Aisner J, Arriagada R, Green MR, Martini N, Perry MC (eds) Comprehensive textbook of thoracic oncology. Williams and Wilkins, Baltimore, p 339
18. 18. Parkin DM, Pisani P, Ferlay J (1999) Global cancer statistics. CA 49: 33
19. 19. Patel AM, Jett JR (1996) Clinical presentation and staging of lung cancer. In: Aisner J, Arriagada R, Green MR, Martini N, Perry MC (eds) Comprehensive textbook of thoracic oncology. Williams and Wilkins, Baltimore, p 293
20. 20. Perera PY, Qureshi N, Vogel SN (1996) Paclitaxel (taxol)-induced NF-κB translocation in murine macrophages. Infect Immun 64: 878
21. 21. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
22. 22. Sano H, Nakagawa N, Chiba R, Kurasawa K, Saito Y, Iwamoto I (1998) Cross-linking of intercellular adhesion molecule-1 induces interleukin-8 and RANTES production through the activation of MAP kinases in human vascular endothelial cells. Biochem Biophys Res Commun 250: 694
23. 23. Schiff PB, Horwitz S (1980) Taxol stabilizes microtubules in mouse fibroblast cells. Proc Natl Acad Sci USA 77: 1561
24. 24. Singh RK, Gutman M, Radinsky R, Bucana CD, Fidler IJ (1994) Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res 54: 3242
25. 25. Smith DR, Polverini PJ, Kunkel SL, Orringer MB, Whyte RI, Burdick MD, Wilke CA, Strieter RM (1994) Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma. J Exp Med 179: 1409
26. 26. Wang C-Y, Mayo MW, Baldwin ASJ (1996) TNF and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274: 784
27. 27. Wang T-Z, Wang H-S, Ichijo H, Giannakakou P, Foster JS, Fojo T, Wimalasena J (1998) Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways. J Biol Chem 273: 4928
28. 28. Wang CY, Cusack JC Jr, Liu R, Baldwin AS Jr (1999) Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nat Med 5: 412