Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

Development (Cambridge)

Volumn 141, Issue 14, 2014, Pages 2770-2779

  Abranches, Elsa ^a,b   Guedes, Ana M V ^a,b   Moravec, Martin ^c   Maamar, Hedia ^d   Svoboda, Petr ^c   Raj, Arjun ^d   Henrique, Domingos ^a,b  

^a UNIVERSITY OF LISBON   (Portugal)

^b CHAMPALIMAUD CENTRE FOR THE UNKNOWN   (Portugal)

^c INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Gene expression heterogeneity; Lineage priming; Nanog; Pluripotency; Stem cells

Indexed keywords

LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA; TRANSCRIPTION FACTOR NANOG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; KINETICS; LEUKEMIA; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; STABLE EXPRESSION;

GENE EXPRESSION HETEROGENEITY; LINEAGE PRIMING; NANOG; PLURIPOTENCY; STEM CELLS;

ANIMALS; CELL LINE; CELL LINEAGE; CELL PROLIFERATION; CLONE CELLS; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; KINETICS; MICE; PLURIPOTENT STEM CELLS; PRINCIPAL COMPONENT ANALYSIS; RNA, MESSENGER; STOCHASTIC PROCESSES; TIME-LAPSE IMAGING; TRANSCRIPTION, GENETIC;

EID: 84904012047     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.108910     Document Type: Article

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