메뉴 건너뛰기




Volumn 11, Issue 7, 2014, Pages 2092-2105

Suitability of porcine chondrocyte micromass culture to model osteoarthritis in vitro

Author keywords

comparative gene expression analysis; in vitro 3D model; porcine chondrocyte high density micromass culture; tumor necrosis factor alpha

Indexed keywords

ADAM10 ENDOPEPTIDASE; CHEMOKINE RECEPTOR CXCR4; COLLAGEN; COLLAGENASE 3; CXCL2 CHEMOKINE; GELATINASE A; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEOGLYCAN; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR TWIST1; TRANSCRIPTION FACTOR WIF1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; CHEMOKINE; COLLAGEN TYPE 2; TUMOR NECROSIS FACTOR ALPHA;

EID: 84903995709     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp5000554     Document Type: Article
Times cited : (23)

References (71)
  • 2
    • 33645234002 scopus 로고    scopus 로고
    • Osteoarthritis
    • Hunter, D. J.; Felson, D. T. Osteoarthritis BMJ 2006, 332, 639-642
    • (2006) BMJ , vol.332 , pp. 639-642
    • Hunter, D.J.1    Felson, D.T.2
  • 4
    • 84885911247 scopus 로고    scopus 로고
    • Role of inflammation in the pathogenesis of osteoarthritis: Latest findings and interpretations
    • Sokolove, J.; Lepus, C. M. Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations Ther. Adv. Musculoskeletal Dis. 2013, 5, 77-94
    • (2013) Ther. Adv. Musculoskeletal Dis. , vol.5 , pp. 77-94
    • Sokolove, J.1    Lepus, C.M.2
  • 5
    • 0035076295 scopus 로고    scopus 로고
    • Articular cartilage and changes in arthritis. An introduction: Cell biology of osteoarthritis
    • Sandell, L. J.; Aigner, T. Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis Arthritis Res. 2001, 3, 107-113
    • (2001) Arthritis Res. , vol.3 , pp. 107-113
    • Sandell, L.J.1    Aigner, T.2
  • 6
    • 84861366755 scopus 로고    scopus 로고
    • Pharmaceutical therapy for osteoarthritis
    • Cheng, D. S.; Visco, C. J. Pharmaceutical therapy for osteoarthritis PM R 2012, 4, S82-88
    • (2012) PM R , vol.4 , pp. 82-88
    • Cheng, D.S.1    Visco, C.J.2
  • 7
    • 79955026286 scopus 로고    scopus 로고
    • Sulforaphane protects human chondrocytes against cell death induced by various stimuli
    • Facchini, A.; Stanic, I.; Cetrullo, S.; Borzi, R. M.; Filardo, G.; Flamigni, F. Sulforaphane protects human chondrocytes against cell death induced by various stimuli J. Cell. Physiol. 2011, 226, 1771-1779
    • (2011) J. Cell. Physiol. , vol.226 , pp. 1771-1779
    • Facchini, A.1    Stanic, I.2    Cetrullo, S.3    Borzi, R.M.4    Filardo, G.5    Flamigni, F.6
  • 8
    • 84872450871 scopus 로고    scopus 로고
    • Collagen metabolism of human osteoarthritic articular cartilage as modulated by bovine collagen hydrolysates
    • Schadow, S.; Siebert, H. C.; Lochnit, G.; Kordelle, J.; Rickert, M.; Steinmeyer, J. Collagen metabolism of human osteoarthritic articular cartilage as modulated by bovine collagen hydrolysates PLoS One 2013, 8, e53955
    • (2013) PLoS One , vol.8 , pp. 53955
    • Schadow, S.1    Siebert, H.C.2    Lochnit, G.3    Kordelle, J.4    Rickert, M.5    Steinmeyer, J.6
  • 10
    • 84872599837 scopus 로고    scopus 로고
    • A review of human pluripotent stem cell-derived cardiomyocytes for high-throughput drug discovery, cardiotoxicity screening, and publication standards
    • Mordwinkin, N. M.; Burridge, P. W.; Wu, J. C. A review of human pluripotent stem cell-derived cardiomyocytes for high-throughput drug discovery, cardiotoxicity screening, and publication standards J. Cardiovasc. Transl. Res. 2013, 6, 22-30
    • (2013) J. Cardiovasc. Transl. Res. , vol.6 , pp. 22-30
    • Mordwinkin, N.M.1    Burridge, P.W.2    Wu, J.C.3
  • 12
    • 84869414892 scopus 로고    scopus 로고
    • Perspective from the heart: The potential of human pluripotent stem cell-derived cardiomyocytes
    • Xu, X. Q.; Sun, W. Perspective from the heart: the potential of human pluripotent stem cell-derived cardiomyocytes J. Cell. Biochem. 2013, 114, 39-46
    • (2013) J. Cell. Biochem. , vol.114 , pp. 39-46
    • Xu, X.Q.1    Sun, W.2
  • 13
    • 84873706380 scopus 로고    scopus 로고
    • Potential of Raloxifene in reversing osteoarthritis-like alterations in rat chondrocytes: An in vitro model study
    • Kavas, A.; Cagatay, S. T.; Banerjee, S.; Keskin, D.; Tezcaner, A. Potential of Raloxifene in reversing osteoarthritis-like alterations in rat chondrocytes: an in vitro model study J. Biosci. 2013, 38, 135-147
    • (2013) J. Biosci. , vol.38 , pp. 135-147
    • Kavas, A.1    Cagatay, S.T.2    Banerjee, S.3    Keskin, D.4    Tezcaner, A.5
  • 14
    • 84903994266 scopus 로고    scopus 로고
    • Induction of high temperature requirement A1, a serine protease, by TGF-beta1 in articular chondrocytes of mouse models of OA
    • in press
    • Xu, L.; Golshirazian, I.; Asbury, B. J.; Li, Y. Induction of high temperature requirement A1, a serine protease, by TGF-beta1 in articular chondrocytes of mouse models of OA. Histol. Histopathol. 2013, in press
    • (2013) Histol. Histopathol.
    • Xu, L.1    Golshirazian, I.2    Asbury, B.J.3    Li, Y.4
  • 19
    • 84879661626 scopus 로고    scopus 로고
    • Matrix-Embedded Cytokines to Simulate Osteoarthritis-Like Cartilage Microenvironments
    • Murab, S.; Chameettachal, S.; Bhattacharjee, M.; Das, S.; Kaplan, D. L.; Ghosh, S. Matrix-Embedded Cytokines to Simulate Osteoarthritis-Like Cartilage Microenvironments Tissue Eng., Part A 2013, 19 (15-16) 1733-1753
    • (2013) Tissue Eng., Part A , vol.19 , Issue.1516 , pp. 1733-1753
    • Murab, S.1    Chameettachal, S.2    Bhattacharjee, M.3    Das, S.4    Kaplan, D.L.5    Ghosh, S.6
  • 20
    • 0031047265 scopus 로고    scopus 로고
    • Synovial membrane inflammation and cytokine production in patients with early osteoarthritis
    • Smith, M. D.; Triantafillou, S.; Parker, A.; Youssef, P. P.; Coleman, M. Synovial membrane inflammation and cytokine production in patients with early osteoarthritis J. Rheumatol. 1997, 24, 365-371
    • (1997) J. Rheumatol. , vol.24 , pp. 365-371
    • Smith, M.D.1    Triantafillou, S.2    Parker, A.3    Youssef, P.P.4    Coleman, M.5
  • 21
    • 0022552896 scopus 로고
    • Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue
    • Farndale, R. W.; Buttle, D. J.; Barrett, A. J. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue Biochim. Biophys. Acta 1986, 883, 173-177
    • (1986) Biochim. Biophys. Acta , vol.883 , pp. 173-177
    • Farndale, R.W.1    Buttle, D.J.2    Barrett, A.J.3
  • 22
    • 0029881336 scopus 로고    scopus 로고
    • A simplified method for the analysis of hydroxyproline in biological tissues
    • Reddy, G. K.; Enwemeka, C. S. A simplified method for the analysis of hydroxyproline in biological tissues Clin. Biochem. 1996, 29, 225-229
    • (1996) Clin. Biochem. , vol.29 , pp. 225-229
    • Reddy, G.K.1    Enwemeka, C.S.2
  • 24
    • 77954143899 scopus 로고    scopus 로고
    • Gene expression profiling of primary human articular chondrocytes in high-density micromasses reveals patterns of recovery, maintenance, re- and dedifferentiation
    • Dehne, T.; Schenk, R.; Perka, C.; Morawietz, L.; Pruss, A.; Sittinger, M.; Kaps, C.; Ringe, J. Gene expression profiling of primary human articular chondrocytes in high-density micromasses reveals patterns of recovery, maintenance, re- and dedifferentiation Gene 2010, 462, 8-17
    • (2010) Gene , vol.462 , pp. 8-17
    • Dehne, T.1    Schenk, R.2    Perka, C.3    Morawietz, L.4    Pruss, A.5    Sittinger, M.6    Kaps, C.7    Ringe, J.8
  • 27
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M. W. A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res. 2001, 29, e45
    • (2001) Nucleic Acids Res. , vol.29 , pp. 45
    • Pfaffl, M.W.1
  • 28
    • 0000923503 scopus 로고
    • Asymptotic Theory of Certain "goodness of Fit" Criteria Based on Stochastic Processes
    • Anderson, T. W.; Darling, D. A. Asymptotic Theory of Certain "Goodness of Fit" Criteria Based on Stochastic Processes Ann. Math. Stat. 1952, 23, 193-212
    • (1952) Ann. Math. Stat. , vol.23 , pp. 193-212
    • Anderson, T.W.1    Darling, D.A.2
  • 29
    • 0001269634 scopus 로고
    • Non-Normality and Tests on Variances
    • Box, G. E. P. Non-Normality and Tests on Variances Biometrika 1953, 40, 318-335
    • (1953) Biometrika , vol.40 , pp. 318-335
    • Box, G.E.P.1
  • 30
    • 84870267223 scopus 로고
    • The generalization of "students" problem when several different population variances are involved
    • Welch, B. L. The generalization of "Students" problem when several different population variances are involved Biometrika 1947, 34, 28-35
    • (1947) Biometrika , vol.34 , pp. 28-35
    • Welch, B.L.1
  • 31
    • 0001165055 scopus 로고
    • Frequency distrubtion of the vlaues of the correlation coefficient in samples from an indefinitely large population
    • Fisher, R. A. Frequency distrubtion of the vlaues of the correlation coefficient in samples from an indefinitely large population Biometrika 1915, 10, 507-521
    • (1915) Biometrika , vol.10 , pp. 507-521
    • Fisher, R.A.1
  • 34
    • 33746682471 scopus 로고    scopus 로고
    • The chondrocyte: Biology and clinical application
    • Lin, Z.; Willers, C.; Xu, J.; Zheng, M. H. The chondrocyte: biology and clinical application Tissue Eng. 2006, 12, 1971-1984
    • (2006) Tissue Eng. , vol.12 , pp. 1971-1984
    • Lin, Z.1    Willers, C.2    Xu, J.3    Zheng, M.H.4
  • 35
    • 84884239861 scopus 로고    scopus 로고
    • The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis
    • Maldonado, M.; Nam, J. The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis Biomed. Res. Int. 2013, 284873
    • (2013) Biomed. Res. Int. , pp. 284873
    • Maldonado, M.1    Nam, J.2
  • 36
    • 34247568901 scopus 로고    scopus 로고
    • Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis
    • Mitsuyama, H.; Healey, R. M.; Terkeltaub, R. A.; Coutts, R. D.; Amiel, D. Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis Osteoarthritis Cartilage 2007, 15, 559-565
    • (2007) Osteoarthritis Cartilage , vol.15 , pp. 559-565
    • Mitsuyama, H.1    Healey, R.M.2    Terkeltaub, R.A.3    Coutts, R.D.4    Amiel, D.5
  • 41
    • 0033696610 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis
    • Kaneko, S.; Satoh, T.; Chiba, J.; Ju, C.; Inoue, K.; Kagawa, J. Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis Cytokines Cell. Mol. Ther. 2000, 6, 71-79
    • (2000) Cytokines Cell. Mol. Ther. , vol.6 , pp. 71-79
    • Kaneko, S.1    Satoh, T.2    Chiba, J.3    Ju, C.4    Inoue, K.5    Kagawa, J.6
  • 42
    • 0036161903 scopus 로고    scopus 로고
    • Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4
    • Kanbe, K.; Takagishi, K.; Chen, Q. Stimulation of matrix metalloprotease 3 release from human chondrocytes by the interaction of stromal cell-derived factor 1 and CXC chemokine receptor 4 Arthritis Rheum. 2002, 46, 130-137
    • (2002) Arthritis Rheum. , vol.46 , pp. 130-137
    • Kanbe, K.1    Takagishi, K.2    Chen, Q.3
  • 43
    • 84864612753 scopus 로고    scopus 로고
    • Association of CXCL12 levels in synovial fluid with the radiographic severity of knee osteoarthritis
    • Xu, Q.; Sun, X. C.; Shang, X. P.; Jiang, H. S. Association of CXCL12 levels in synovial fluid with the radiographic severity of knee osteoarthritis J. Invest. Med. 2012, 60, 898-901
    • (2012) J. Invest. Med. , vol.60 , pp. 898-901
    • Xu, Q.1    Sun, X.C.2    Shang, X.P.3    Jiang, H.S.4
  • 44
    • 55349088908 scopus 로고    scopus 로고
    • Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta
    • Sandell, L. J.; Xing, X.; Franz, C.; Davies, S.; Chang, L. W.; Patra, D. Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta Osteoarthritis Cartilage 2008, 16, 1560-1571
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1560-1571
    • Sandell, L.J.1    Xing, X.2    Franz, C.3    Davies, S.4    Chang, L.W.5    Patra, D.6
  • 46
    • 33745044261 scopus 로고    scopus 로고
    • Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes
    • Lopez-Armada, M. J.; Carames, B.; Lires-Dean, M.; Cillero-Pastor, B.; Ruiz-Romero, C.; Galdo, F.; Blanco, F. J. Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes Osteoarthritis Cartilage 2006, 14, 660-669
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 660-669
    • Lopez-Armada, M.J.1    Carames, B.2    Lires-Dean, M.3    Cillero-Pastor, B.4    Ruiz-Romero, C.5    Galdo, F.6    Blanco, F.J.7
  • 48
    • 67649479387 scopus 로고    scopus 로고
    • Mesenchymal progenitor cell markers in human articular cartilage: Normal distribution and changes in osteoarthritis
    • Grogan, S. P.; Miyaki, S.; Asahara, H.; DLima, D. D.; Lotz, M. K. Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis Arthritis Res. Ther. 2009, 11, R85
    • (2009) Arthritis Res. Ther. , vol.11 , pp. 85
    • Grogan, S.P.1    Miyaki, S.2    Asahara, H.3    Dlima, D.D.4    Lotz, M.K.5
  • 49
    • 78751569921 scopus 로고    scopus 로고
    • Characterization of apoptosis in articular cartilage derived from the knee joints of patients with osteoarthritis
    • Musumeci, G.; Loreto, C.; Carnazza, M. L.; Martinez, G. Characterization of apoptosis in articular cartilage derived from the knee joints of patients with osteoarthritis Knee Surg. Sports Traumatol. Arthrosc. 2011, 19, 307-313
    • (2011) Knee Surg. Sports Traumatol. Arthrosc. , vol.19 , pp. 307-313
    • Musumeci, G.1    Loreto, C.2    Carnazza, M.L.3    Martinez, G.4
  • 51
    • 40349084129 scopus 로고    scopus 로고
    • Haem oxygenase-1 regulates catabolic and anabolic processes in osteoarthritic chondrocytes
    • Guillen, M.; Megias, J.; Gomar, F.; Alcaraz, M. Haem oxygenase-1 regulates catabolic and anabolic processes in osteoarthritic chondrocytes J. Pathol. 2008, 214, 515-522
    • (2008) J. Pathol. , vol.214 , pp. 515-522
    • Guillen, M.1    Megias, J.2    Gomar, F.3    Alcaraz, M.4
  • 52
    • 84873175958 scopus 로고    scopus 로고
    • Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees
    • Chou, C. H.; Lee, C. H.; Lu, L. S.; Song, I. W.; Chuang, H. P.; Kuo, S. Y.; Wu, J. Y.; Chen, Y. T.; Kraus, V. B.; Wu, C. C.; Lee, M. T. Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees Osteoarthritis Cartilage 2013, 21, 450-461
    • (2013) Osteoarthritis Cartilage , vol.21 , pp. 450-461
    • Chou, C.H.1    Lee, C.H.2    Lu, L.S.3    Song, I.W.4    Chuang, H.P.5    Kuo, S.Y.6    Wu, J.Y.7    Chen, Y.T.8    Kraus, V.B.9    Wu, C.C.10    Lee, M.T.11
  • 54
    • 18244406789 scopus 로고    scopus 로고
    • Enhanced expression of insulin-like growth factor-binding proteins in human osteoarthritic cartilage detected by immunohistochemistry and in situ hybridization
    • Iwanaga, H.; Matsumoto, T.; Enomoto, H.; Okano, K.; Hishikawa, Y.; Shindo, H.; Koji, T. Enhanced expression of insulin-like growth factor-binding proteins in human osteoarthritic cartilage detected by immunohistochemistry and in situ hybridization Osteoarthritis Cartilage 2005, 13, 439-448
    • (2005) Osteoarthritis Cartilage , vol.13 , pp. 439-448
    • Iwanaga, H.1    Matsumoto, T.2    Enomoto, H.3    Okano, K.4    Hishikawa, Y.5    Shindo, H.6    Koji, T.7
  • 57
    • 33644632174 scopus 로고    scopus 로고
    • Early and stable upregulation of collagen type II, collagen type i and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading
    • Lorenz, H.; Wenz, W.; Ivancic, M.; Steck, E.; Richter, W. Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading Arthritis Res. Ther. 2005, 7, R156-165
    • (2005) Arthritis Res. Ther. , vol.7 , pp. 156-165
    • Lorenz, H.1    Wenz, W.2    Ivancic, M.3    Steck, E.4    Richter, W.5
  • 58
    • 77951021911 scopus 로고    scopus 로고
    • Changes in content and synthesis of collagen types and proteoglycans in osteoarthritis of the knee joint and comparison of quantitative analysis with Photoshop-based image analysis
    • Lahm, A.; Mrosek, E.; Spank, H.; Erggelet, C.; Kasch, R.; Esser, J.; Merk, H. Changes in content and synthesis of collagen types and proteoglycans in osteoarthritis of the knee joint and comparison of quantitative analysis with Photoshop-based image analysis Arch. Orthop. Trauma. Surg. 2010, 130, 557-564
    • (2010) Arch. Orthop. Trauma. Surg. , vol.130 , pp. 557-564
    • Lahm, A.1    Mrosek, E.2    Spank, H.3    Erggelet, C.4    Kasch, R.5    Esser, J.6    Merk, H.7
  • 59
    • 18744385527 scopus 로고    scopus 로고
    • Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions
    • Tchetina, E. V.; Squires, G.; Poole, A. R. Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions J. Rheumatol. 2005, 32, 876-886
    • (2005) J. Rheumatol. , vol.32 , pp. 876-886
    • Tchetina, E.V.1    Squires, G.2    Poole, A.R.3
  • 60
    • 24344466984 scopus 로고    scopus 로고
    • Intrajoint comparisons of gene expression patterns in human osteoarthritis suggest a change in chondrocyte phenotype
    • Yagi, R.; McBurney, D.; Laverty, D.; Weiner, S.; Horton, W. E., Jr. Intrajoint comparisons of gene expression patterns in human osteoarthritis suggest a change in chondrocyte phenotype J. Orthop. Res. 2005, 23, 1128-1138
    • (2005) J. Orthop. Res. , vol.23 , pp. 1128-1138
    • Yagi, R.1    McBurney, D.2    Laverty, D.3    Weiner, S.4    Horton, Jr.W.E.5
  • 61
    • 33744479689 scopus 로고    scopus 로고
    • Chondrocyte gene expression in osteoarthritis: Correlation with disease severity
    • Eid, K.; Thornhill, T. S.; Glowacki, J. Chondrocyte gene expression in osteoarthritis: Correlation with disease severity J. Orthop. Res. 2006, 24, 1062-1068
    • (2006) J. Orthop. Res. , vol.24 , pp. 1062-1068
    • Eid, K.1    Thornhill, T.S.2    Glowacki, J.3
  • 62
    • 73449143498 scopus 로고    scopus 로고
    • Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy
    • Brew, C. J.; Clegg, P. D.; Boot-Handford, R. P.; Andrew, J. G.; Hardingham, T. Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy Ann. Rheum. Dis. 2010, 69, 234-240
    • (2010) Ann. Rheum. Dis. , vol.69 , pp. 234-240
    • Brew, C.J.1    Clegg, P.D.2    Boot-Handford, R.P.3    Andrew, J.G.4    Hardingham, T.5
  • 63
    • 84887257998 scopus 로고    scopus 로고
    • Molecular characterization of articular cartilage from young adults with femoroacetabular impingement
    • Hashimoto, S.; Rai, M. F.; Gill, C. S.; Zhang, Z.; Sandell, L. J.; Clohisy, J. C. Molecular characterization of articular cartilage from young adults with femoroacetabular impingement J. Bone Jt. Surg., Am. Vol. 2013, 95, 1457-1464
    • (2013) J. Bone Jt. Surg., Am. Vol. , vol.95 , pp. 1457-1464
    • Hashimoto, S.1    Rai, M.F.2    Gill, C.S.3    Zhang, Z.4    Sandell, L.J.5    Clohisy, J.C.6
  • 66
    • 0034603036 scopus 로고    scopus 로고
    • Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha
    • Murakami, S.; Lefebvre, V.; de Crombrugghe, B. Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha J. Biol. Chem. 2000, 275, 3687-3692
    • (2000) J. Biol. Chem. , vol.275 , pp. 3687-3692
    • Murakami, S.1    Lefebvre, V.2    De Crombrugghe, B.3
  • 68
    • 5644300642 scopus 로고    scopus 로고
    • Expression of collagen type i and type II in consecutive stages of human osteoarthritis
    • Miosge, N.; Hartmann, M.; Maelicke, C.; Herken, R. Expression of collagen type I and type II in consecutive stages of human osteoarthritis Histochem. Cell Biol. 2004, 122, 229-236
    • (2004) Histochem. Cell Biol. , vol.122 , pp. 229-236
    • Miosge, N.1    Hartmann, M.2    Maelicke, C.3    Herken, R.4
  • 69
    • 7944226150 scopus 로고    scopus 로고
    • Altered patterns and synthesis of extracellular matrix macromolecules in early osteoarthritis
    • Lorenzo, P.; Bayliss, M. T.; Heinegard, D. Altered patterns and synthesis of extracellular matrix macromolecules in early osteoarthritis Matrix Biol. 2004, 23, 381-391
    • (2004) Matrix Biol. , vol.23 , pp. 381-391
    • Lorenzo, P.1    Bayliss, M.T.2    Heinegard, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.