-
1
-
-
84861827675
-
Osteoarthritis: A disease of the joint as an organ
-
[review].
-
Loeser RF, Goldring SR, Scanzello CR, Goldring MB,. Osteoarthritis: a disease of the joint as an organ [review]. Arthritis Rheum 2012; 64: 1697-707.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1697-1707
-
-
Loeser, R.F.1
Goldring, S.R.2
Scanzello, C.R.3
Goldring, M.B.4
-
2
-
-
84863221746
-
The growing array of innate inflammatory ignition switches in osteoarthritis
-
[editorial].
-
Liu-Bryan R, Terkeltaub R,. The growing array of innate inflammatory ignition switches in osteoarthritis [editorial]. Arthritis Rheum 2012; 64: 2055-8.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2055-2058
-
-
Liu-Bryan, R.1
Terkeltaub, R.2
-
3
-
-
84857737250
-
Osteoarthritis as an autoinflammatory disease caused by chondrocyte-mediated inflammatory responses
-
Konttinen YT, Sillat T, Barreto G, Ainola M, Nordstrom DC,. Osteoarthritis as an autoinflammatory disease caused by chondrocyte-mediated inflammatory responses. Arthritis Rheum 2012; 64: 613-6.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 613-616
-
-
Konttinen, Y.T.1
Sillat, T.2
Barreto, G.3
Ainola, M.4
Nordstrom, D.C.5
-
4
-
-
0029981825
-
Cytokines in osteoarthritis: Mediators or markers of joint destruction?
-
Westacott CI, Sharif M,. Cytokines in osteoarthritis: mediators or markers of joint destruction? Semin Arthritis Rheum 1996; 25: 254-72.
-
(1996)
Semin Arthritis Rheum
, vol.25
, pp. 254-272
-
-
Westacott, C.I.1
Sharif, M.2
-
5
-
-
0025905168
-
In vivo effects of interleukin-1 on articular cartilage: Prolongation of proteoglycan metabolic disturbances in old mice
-
Van Beuningen HM, Arntz O, van den Berg WB,. In vivo effects of interleukin-1 on articular cartilage: prolongation of proteoglycan metabolic disturbances in old mice. Arthritis Rheum 1991; 34: 606-15.
-
(1991)
Arthritis Rheum
, vol.34
, pp. 606-615
-
-
Van Beuningen, H.M.1
Arntz, O.2
Van Den Berg, W.B.3
-
6
-
-
0036822797
-
Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
-
Bau B, Gebhard PM, Haag J, Knorr T, Bartnik E, Aigner T,. Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro. Arthritis Rheum 2002; 46: 2648-57.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2648-2657
-
-
Bau, B.1
Gebhard, P.M.2
Haag, J.3
Knorr, T.4
Bartnik, E.5
Aigner, T.6
-
8
-
-
0031194918
-
Effect of interleukin-1 and leukemia inhibitory factor on chondrocyte metabolism in articular cartilage from normal and interleukin-6-deficient mice: Role of nitric oxide and IL-6 in the suppression of proteoglycan synthesis
-
Van de Loo FA, Arntz OJ, Van den Berg WB,. Effect of interleukin-1 and leukemia inhibitory factor on chondrocyte metabolism in articular cartilage from normal and interleukin-6-deficient mice: role of nitric oxide and IL-6 in the suppression of proteoglycan synthesis. Cytokine 1997; 9: 453-62.
-
(1997)
Cytokine
, vol.9
, pp. 453-462
-
-
Van De Loo, F.A.1
Arntz, O.J.2
Van Den Berg, W.B.3
-
9
-
-
0030964252
-
Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: Prolyl hydroxylase as a possible target
-
Cao M, Westerhausen-Larson A, Niyibizi C, Kavalkovich K, Georgescu HI, Rizzo CF, et al. Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target. Biochem J 1997; 324: 305-10.
-
(1997)
Biochem J
, vol.324
, pp. 305-310
-
-
Cao, M.1
Westerhausen-Larson, A.2
Niyibizi, C.3
Kavalkovich, K.4
Georgescu, H.I.5
Rizzo, C.F.6
-
10
-
-
0028830920
-
Chondrocyte apoptosis induced by nitric oxide
-
Blanco FJ, Ochs RL, Schwarz H, Lotz M,. Chondrocyte apoptosis induced by nitric oxide. Am J Pathol 1995; 146: 75-85.
-
(1995)
Am J Pathol
, vol.146
, pp. 75-85
-
-
Blanco, F.J.1
Ochs, R.L.2
Schwarz, H.3
Lotz, M.4
-
11
-
-
0033166177
-
Animal models of arthritis in NOS2-deficient mice
-
Van den Berg WB, van de Loo F, Joosten LA, Arntz OJ,. Animal models of arthritis in NOS2-deficient mice. Osteoarthritis Cartilage 1999; 7: 413-5.
-
(1999)
Osteoarthritis Cartilage
, vol.7
, pp. 413-415
-
-
Van Den Berg, W.B.1
Van De Loo, F.2
Joosten, L.A.3
Arntz, O.J.4
-
12
-
-
0346658320
-
Gene deletion of either interleukin-1β, interleukin-1β- converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy
-
Clements KM, Price JS, Chambers MG, Visco DM, Poole AR, Mason RM,. Gene deletion of either interleukin-1β, interleukin-1β-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy. Arthritis Rheum 2003; 48: 3452-63.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3452-3463
-
-
Clements, K.M.1
Price, J.S.2
Chambers, M.G.3
Visco, D.M.4
Poole, A.R.5
Mason, R.M.6
-
13
-
-
0029773518
-
Characterization and functional analysis of the human inducible nitric oxide synthase gene promoter
-
Spitsin SV, Koprowski H, Michaels FH,. Characterization and functional analysis of the human inducible nitric oxide synthase gene promoter. Mol Med 1996; 2: 226-35.
-
(1996)
Mol Med
, vol.2
, pp. 226-235
-
-
Spitsin, S.V.1
Koprowski, H.2
Michaels, F.H.3
-
14
-
-
0034531763
-
Differential effects of SB 242235, a selective p38 mitogen-activated protein kinase inhibitor, on IL-1 treated bovine and human cartilage/chondrocyte cultures
-
Badger AM, Roshak AK, Cook MN, Newman-Tarr TM, Swift BA, Carlson K, et al. Differential effects of SB 242235, a selective p38 mitogen-activated protein kinase inhibitor, on IL-1 treated bovine and human cartilage/chondrocyte cultures. Osteoarthritis Cartilage 2000; 8: 434-43.
-
(2000)
Osteoarthritis Cartilage
, vol.8
, pp. 434-443
-
-
Badger, A.M.1
Roshak, A.K.2
Cook, M.N.3
Newman-Tarr, T.M.4
Swift, B.A.5
Carlson, K.6
-
15
-
-
52949116440
-
Retinoid acid inhibits IL-1-induced iNOS, COX-2 and chemokine production in human chondrocytes
-
Hung LF, Lai JH, Lin LC, Wang SJ, Hou TY, Chang DM, et al. Retinoid acid inhibits IL-1-induced iNOS, COX-2 and chemokine production in human chondrocytes. Immunol Invest 2008; 37: 675-93.
-
(2008)
Immunol Invest
, vol.37
, pp. 675-693
-
-
Hung, L.F.1
Lai, J.H.2
Lin, L.C.3
Wang, S.J.4
Hou, T.Y.5
Chang, D.M.6
-
16
-
-
39749120480
-
Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes
-
Stradner MH, Hermann J, Angerer H, Setznagl D, Sunk IG, Windhager R, et al. Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes. Osteoarthritis Cartilage 2008; 16: 305-11.
-
(2008)
Osteoarthritis Cartilage
, vol.16
, pp. 305-311
-
-
Stradner, M.H.1
Hermann, J.2
Angerer, H.3
Setznagl, D.4
Sunk, I.G.5
Windhager, R.6
-
17
-
-
0027371722
-
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
-
Olivera A, Spiegel S,. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 1993; 365: 557-60.
-
(1993)
Nature
, vol.365
, pp. 557-560
-
-
Olivera, A.1
Spiegel, S.2
-
19
-
-
0033783522
-
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
-
Liu Y, Wada R, Yamashita T, Mi Y, Deng CX, Hobson JP, et al. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J Clin Invest 2000; 106: 951-61.
-
(2000)
J Clin Invest
, vol.106
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
Mi, Y.4
Deng, C.X.5
Hobson, J.P.6
-
20
-
-
0037162037
-
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors
-
Kluk MJ, Hla T,. Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors. Biochim Biophys Acta 2002; 1582: 72-80.
-
(2002)
Biochim Biophys Acta
, vol.1582
, pp. 72-80
-
-
Kluk, M.J.1
Hla, T.2
-
21
-
-
33646385932
-
Sphingosine-1-phosphate stimulates rat primary chondrocyte proliferation
-
Kim MK, Lee HY, Kwak JY, Park JI, Yun J, Bae YS,. Sphingosine-1-phosphate stimulates rat primary chondrocyte proliferation. Biochem Biophys Res Commun 2006; 345: 67-73.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 67-73
-
-
Kim, M.K.1
Lee, H.Y.2
Kwak, J.Y.3
Park, J.I.4
Yun, J.5
Bae, Y.S.6
-
23
-
-
33644880217
-
Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: Regulation of synovial proliferation and inflammatory gene expression
-
[published erratum appears in Arthritis Rheum 2006;54:1704].
-
Kitano M, Hla T, Sekiguchi M, Kawahito Y, Yoshimura R, Miyazawa K, et al. Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: regulation of synovial proliferation and inflammatory gene expression [published erratum appears in Arthritis Rheum 2006;54:1704]. Arthritis Rheum 2006; 54: 742-53.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 742-753
-
-
Kitano, M.1
Hla, T.2
Sekiguchi, M.3
Kawahito, Y.4
Yoshimura, R.5
Miyazawa, K.6
-
24
-
-
33644885430
-
Sphingosine kinase 1-mediated inhibition of Fas death signaling in rheumatoid arthritis B lymphoblastoid cells
-
Pi X, Tan SY, Hayes M, Xiao L, Shayman JA, Ling S, et al. Sphingosine kinase 1-mediated inhibition of Fas death signaling in rheumatoid arthritis B lymphoblastoid cells. Arthritis Rheum 2006; 54: 754-64.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 754-764
-
-
Pi, X.1
Tan, S.Y.2
Hayes, M.3
Xiao, L.4
Shayman, J.A.5
Ling, S.6
-
25
-
-
84869469917
-
Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes
-
Moon MH, Jeong JK, Lee YJ, Seol JW, Park SY,. Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes. Int J Mol Med 2012; 30: 1451-8.
-
(2012)
Int J Mol Med
, vol.30
, pp. 1451-1458
-
-
Moon, M.H.1
Jeong, J.K.2
Lee, Y.J.3
Seol, J.W.4
Park, S.Y.5
-
26
-
-
84865297437
-
Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: A possible new role in arthritis
-
Masuko K, Murata M, Beppu M, Nakamura H, Kato T, Yudoh K,. Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis. Int J Rheum Dis 2012; 15: 366-73.
-
(2012)
Int J Rheum Dis
, vol.15
, pp. 366-373
-
-
Masuko, K.1
Murata, M.2
Beppu, M.3
Nakamura, H.4
Kato, T.5
Yudoh, K.6
-
27
-
-
83455259337
-
Regulation of MMP3 by laminin α4 in human osteoarthritic cartilage
-
Fuerst FC, Gruber G, Stradner MH, Jones JC, Kremser ML, Angerer H, et al. Regulation of MMP3 by laminin α4 in human osteoarthritic cartilage. Scand J Rheumatol 2011; 40: 494-6.
-
(2011)
Scand J Rheumatol
, vol.40
, pp. 494-496
-
-
Fuerst, F.C.1
Gruber, G.2
Stradner, M.H.3
Jones, J.C.4
Kremser, M.L.5
Angerer, H.6
-
28
-
-
29844453023
-
Osteoarthritis cartilage histopathology: Grading and staging
-
Pritzker KP, Gay S, Jimenez SA, Ostergaard K, Pelletier JP, Revell PA, et al. Osteoarthritis cartilage histopathology: grading and staging. Osteoarthritis Cartilage 2006; 14: 13-29.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 13-29
-
-
Pritzker, K.P.1
Gay, S.2
Jimenez, S.A.3
Ostergaard, K.4
Pelletier, J.P.5
Revell, P.A.6
-
29
-
-
83155163778
-
The immunosuppressant FTY720 (fingolimod) enhances glycosaminoglycan depletion in articular cartilage
-
Stradner MH, Angerer H, Ortner T, Fuerst FC, Setznagl D, Kremser ML, et al. The immunosuppressant FTY720 (fingolimod) enhances glycosaminoglycan depletion in articular cartilage. BMC Musculoskelet Disord 2011; 12: 279.
-
(2011)
BMC Musculoskelet Disord
, vol.12
, pp. 279
-
-
Stradner, M.H.1
Angerer, H.2
Ortner, T.3
Fuerst, F.C.4
Setznagl, D.5
Kremser, M.L.6
-
30
-
-
67449132285
-
Regulation of vascular physiology and pathology by the S1P2 receptor subtype
-
Skoura A, Hla T,. Regulation of vascular physiology and pathology by the S1P2 receptor subtype. Cardiovasc Res 2009; 82: 221-8.
-
(2009)
Cardiovasc Res
, vol.82
, pp. 221-228
-
-
Skoura, A.1
Hla, T.2
-
31
-
-
15444373513
-
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
-
Sanchez T, Thangada S, Wu MT, Kontos CD, Wu D, Wu H, et al. PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. Proc Natl Acad Sci U S A 2005; 102: 4312-7.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4312-4317
-
-
Sanchez, T.1
Thangada, S.2
Wu, M.T.3
Kontos, C.D.4
Wu, D.5
Wu, H.6
-
32
-
-
78049422010
-
Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice
-
Wang F, Okamoto Y, Inoki I, Yoshioka K, Du W, Qi X, et al. Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice. J Clin Invest 2010; 120: 3979-95.
-
(2010)
J Clin Invest
, vol.120
, pp. 3979-3995
-
-
Wang, F.1
Okamoto, Y.2
Inoki, I.3
Yoshioka, K.4
Du, W.5
Qi, X.6
-
33
-
-
0032959716
-
The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways
-
Gonda K, Okamoto H, Takuwa N, Yatomi Y, Okazaki H, Sakurai T, et al. The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways. Biochem J 1999; 337: 67-75.
-
(1999)
Biochem J
, vol.337
, pp. 67-75
-
-
Gonda, K.1
Okamoto, H.2
Takuwa, N.3
Yatomi, Y.4
Okazaki, H.5
Sakurai, T.6
-
34
-
-
0141679087
-
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells
-
Yamaguchi H, Kitayama J, Takuwa N, Arikawa K, Inoki I, Takehara K, et al. Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells. Biochem J 2003; 374: 715-22.
-
(2003)
Biochem J
, vol.374
, pp. 715-722
-
-
Yamaguchi, H.1
Kitayama, J.2
Takuwa, N.3
Arikawa, K.4
Inoki, I.5
Takehara, K.6
-
36
-
-
78650304654
-
Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes
-
Cheng AW, Stabler TV, Bolognesi M, Kraus VB,. Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes. Osteoarthritis Cartilage 2011; 19: 118-25.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, pp. 118-125
-
-
Cheng, A.W.1
Stabler, T.V.2
Bolognesi, M.3
Kraus, V.B.4
-
37
-
-
18744425103
-
Role of mitogen-activated protein kinases and tyrosine kinases on IL-1-induced NF-κB activation and iNOS expression in bovine articular chondrocytes
-
Mendes AF, Caramona MM, Carvalho AP, Lopes MC,. Role of mitogen-activated protein kinases and tyrosine kinases on IL-1-induced NF-κB activation and iNOS expression in bovine articular chondrocytes. Nitric Oxide 2002; 6: 35-44.
-
(2002)
Nitric Oxide
, vol.6
, pp. 35-44
-
-
Mendes, A.F.1
Caramona, M.M.2
Carvalho, A.P.3
Lopes, M.C.4
-
38
-
-
79952914936
-
Synthetic sphingosine 1-phosphate receptor modulators - Opportunities and potential pitfalls
-
Bolli MH, Lescop C, Nayler O,. Synthetic sphingosine 1-phosphate receptor modulators-opportunities and potential pitfalls. Curr Top Med Chem 2011; 11: 726-57.
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 726-757
-
-
Bolli, M.H.1
Lescop, C.2
Nayler, O.3
|