Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees

Osteoarthritis and Cartilage

Volumn 21, Issue 3, 2013, Pages 450-461

  Chou, C H ^a,b,c   Lee, C H ^d,e   Lu, L S ^a,b   Song, I W ^a,b,f   Chuang, H P ^b   Kuo, S Y ^f   Wu, J Y ^a,b   Chen, Y T ^a,c   Kraus, V B ^c   Wu, C C ^f   Lee, M T M ^a,b,g,h  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b ACADEMIA SINICA   (Taiwan)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^g CHINA MEDICAL UNIVERSITY   (Taiwan)

^h RIKEN   (Japan)

Author keywords

Bone sectioning and grinding; Cartilage; Gene expression; Osteoarthritis; RNA isolation; Subchondral bone

Indexed keywords

ADAMTS1 PROTEIN; ASPORIN; BINDING ENDOTHELIAL REGULATOR PROTEIN; BONE MORPHOGENETIC PROTEIN 6; COLLAGEN TYPE 16; COLLAGEN TYPE 16 ALPHA; COLLAGEN TYPE 4; COLLAGEN TYPE 4 ALPHA; COLLAGEN TYPE 6; COLLAGEN TYPE 6 ALPHA 3; MONOCYTE CHEMOTACTIC PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; ARTICULAR CARTILAGE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DOWN REGULATION; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KNEE; KNEE OSTEOARTHRITIS; MICRO-COMPUTED TOMOGRAPHY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RNA ISOLATION; SUBCHONDRAL BONE; UPREGULATION;

AGED; AGED, 80 AND OVER; CARTILAGE, ARTICULAR; FEMALE; GENE EXPRESSION; HUMANS; KNEE JOINT; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; POLYMERASE CHAIN REACTION; RNA; TIBIA; X-RAY MICROTOMOGRAPHY;

EID: 84873175958     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2012.11.016     Document Type: Article

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