A novel disease-modifying osteoarthritis drug candidate targeting Runx1

Annals of the Rheumatic Diseases

Volumn 72, Issue 5, 2013, Pages 748-753

  Yano, Fumiko ^a   Hojo, Hironori ^a   Ohba, Shinsuke ^a   Fukai, Atsushi ^b   Hosaka, Yoko ^b   Ikeda, Toshiyuki ^b   Saito, Taku ^b   Hirata, Makoto ^b   Chikuda, Hirotaka ^b   Takato, Tsuyoshi ^b   Kawaguchi, Hiroshi ^b   Chung, Ung Il ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE MODIFYING ANTIRHEUMATIC DRUG; DISEASE MODIFYING OSTEOARTHRITIS DRUG; INDAZOLE DERIVATIVE; TD 198946; THIENOINDAZOLE DERIVATIVE; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; DOWN REGULATION; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG TARGETING; HYPERTROPHY; JOINT DEGENERATION; MALE; METATARSAL BONE; MICROARRAY ANALYSIS; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; ORGAN CULTURE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIRHEUMATIC AGENTS; CARTILAGE, ARTICULAR; CELL DIFFERENTIATION; CHONDROGENESIS; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DISEASE MODELS, ANIMAL; DRUG DESIGN; GENE EXPRESSION; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; INDAZOLES; INJECTIONS, INTRA-ARTICULAR; KNEE JOINT; MALE; MICE; OSTEOARTHRITIS, KNEE; RNA, MESSENGER;

EID: 84875950652     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2012-201745     Document Type: Article

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