Development of tamoxifen-phospholipid complex: Novel approach for improving solubility and bioavailability

International Journal of Pharmaceutics

Volumn 473, Issue 1-2, 2014, Pages 1-9

  Jena, Sunil Kumar ^a   Singh, Charan ^a   Dora, Chander Parkash ^a   Suresh, Sarasija ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Oral bioavailability; Phospholipid; Solubility; Tamoxifen; Tamoxifen phospholipid complex

Indexed keywords

PHOSPHATIDYLCHOLINE; SOLVENT; TAMOXIFEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG HALF LIFE; DRUG SOLUBILITY; ENTEROHEPATIC CIRCULATION; EVAPORATION; FEMALE; HYDROPHILICITY; HYDROPHOBICITY; INFRARED SPECTROSCOPY; LIPOPHILICITY; LIVER METABOLISM; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; X RAY POWDER DIFFRACTION; ANIMAL; BIOAVAILABILITY; BLOOD; CHEMISTRY; SOLUBILITY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; FEMALE; PHOSPHATIDYLCHOLINES; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TAMOXIFEN;

EID: 84903847343     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.06.056     Document Type: Article

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