Lecithin/chitosan controlled release nanopreparations of tamoxifen citrate: Loading, enzyme-trigger release and cell uptake

Journal of Controlled Release

Volumn 167, Issue 3, 2013, Pages 276-283

  Barbieri, Stefano ^a   Sonvico, Fabio ^a,c   Como, Caterina ^a,d   Colombo, Gaia ^b   Zani, Franca ^a   Buttini, Francesca ^a   Bettini, Ruggero ^a   Rossi, Alessandra ^a   Colombo, Paolo ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^d RES PHARMA   (Italy)

Author keywords

Caco 2; Chitosan; Lecithin; Lysozyme; Nanoparticles; Tamoxifen citrate

Indexed keywords

CACO-2; COLLOIDAL DISPERSION; INTESTINAL EPITHELIUM; MORPHOLOGICAL ANALYSIS; MORPHOLOGICAL PROPERTIES; NANOPARTICLE STRUCTURES; PHYSICOCHEMICAL PROPERTY; TAMOXIFEN CITRATE;

CHEMICAL PROPERTIES; CHITOSAN; CYTOTOXICITY; ENZYMES; LECITHIN; ZETA POTENTIAL;

NANOPARTICLES;

CHITOSAN; NANOPARTICLE; PHOSPHATIDYLCHOLINE; TAMOXIFEN CITRATE;

ARTICLE; CELL STRAIN CACO 2; CELL STRAIN MCF 7; COLLOID; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG UPTAKE; GASTROINTESTINAL SECRETION; HUMAN; HUMAN CELL; LOADING DRUG DOSE; MORPHOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; STRUCTURE ANALYSIS; SURFACE PROPERTY; ZETA POTENTIAL;

ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL SURVIVAL; CHITOSAN; DRUG DELIVERY SYSTEMS; GASTRIC JUICE; HUMANS; INTESTINAL SECRETIONS; LECITHINS; LIPASE; MCF-7 CELLS; MURAMIDASE; NANOPARTICLES; PANCREATIN; PROGESTERONE; TAMOXIFEN;

EID: 84874939223     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.02.009     Document Type: Article

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