Novel rifampicin-phospholipid complex for tubercular therapy: Synthesis, physicochemical characterization and in-vivo evaluation

International Journal of Pharmaceutics

Volumn 460, Issue 1-2, 2014, Pages 220-227

  Singh, Charan ^a   Bhatt, Tara Datt ^a   Gill, Manjinder Singh ^a   Suresh, Sarasija ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Oral bioavailability; Pharmacokinetic; Rifampicin; Rifampicin phospholipid complex

Indexed keywords

ISONIAZID; RIFAMPICIN; RIFAMPICIN PHOSPHOLIPID COMPLEX; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG SCREENING; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; INFRARED SPECTROSCOPY; LIQUID LIQUID EXTRACTION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; STATIC ELECTRICITY; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY POWDER DIFFRACTION;

ORAL BIOAVAILABILITY; PHARMACOKINETIC; RIFAMPICIN; RIFAMPICIN-PHOSPHOLIPID COMPLEX;

ANIMALS; ANTIBIOTICS, ANTITUBERCULAR; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; MALE; MICROSCOPY, ELECTRON, SCANNING; PHOSPHOLIPIDS; POWDER DIFFRACTION; RATS; RATS, SPRAGUE-DAWLEY; RIFAMPIN; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 84892392557     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.10.043     Document Type: Article

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