Regulation of diacylglycerol acyltransferase 2 protein stability by gp78-associated endoplasmic-reticulum-associated degradation

FEBS Journal

Volumn 281, Issue 13, 2014, Pages 3048-3060

  Choi, Kwangman ^a   Kim, Hyeongki ^a,b   Kang, Hyunju ^a   Lee, So Young ^c   Lee, Sang Jun ^a   Back, Sung Hoon ^d   Lee, Seo Hyun ^e   Kim, M Sun ^e   Lee, Jeong Eun ^e   Park, Ju Young ^e   Kim, Jiye ^a   Kim, Sunhong ^a   Song, Jae Hyung ^a   Choi, Yura ^a   Lee, Suui ^a   Lee, Hyun Jun ^a   Kim, Jong Heon ^e   Cho, Sungchan ^a,b  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c National Institute of Food and Drug Safety Evaluation   (South Korea)

^d University of Ulsan   (South Korea)

^e National Cancer Center   (South Korea)

Author keywords

diacylglycerol acyltransferase 2 (DGAT2); E3 ligase; ER associated degradation (ERAD); gp78; triacylglycerol

Indexed keywords

DIACYLGLYCEROL ACYLTRANSFERASE 1; DIACYLGLYCEROL ACYLTRANSFERASE 2; FAT DROPLET; MEMBRANE PROTEIN; PROTEASOME; PROTEIN GP78; REGULATOR PROTEIN; TRANSMEMBRANE DOMAIN 1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DGAT1 GENE; DGAT2 GENE; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENZYME DEGRADATION; ENZYME LOCALIZATION; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION;

EUKARYOTA;

DIACYLGLYCEROL ACYLTRANSFERASE 2 (DGAT2); E3 LIGASE; ER-ASSOCIATED DEGRADATION (ERAD); GP78; TRIACYLGLYCEROL;

CELL LINE, TUMOR; DIACYLGLYCEROL O-ACYLTRANSFERASE; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; ENZYME STABILITY; HEK293 CELLS; HEPATOCYTES; HUMANS; LIPID METABOLISM; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RECEPTORS, AUTOCRINE MOTILITY FACTOR; UBIQUITINATION;

EID: 84903818479     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12841     Document Type: Article

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