The lectin OS-9 delivers mutant neuroserpin to endoplasmic reticulum associated degradation in familial encephalopathy with neuroserpin inclusion bodies

Neurobiology of Aging

Volumn 35, Issue 10, 2014, Pages 2394-2403

  Schipanski, Angela ^a   Oberhauser, Felix ^a   Neumann, Melanie ^a   Lange, Sascha ^a   Szalay, Beata ^a   Krasemann, Susanne ^a   van Leeuwen, Fred W ^b   Galliciotti, Giovanna ^a   Glatzel, Markus ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Dementia; ER associated degradation; Neuropathology; Neuroserpin; Proteasome; Proteostasis

Indexed keywords

GLYCAN; LECTIN; NEUROSERPIN; NEUROPEPTIDE; OS9 PROTEIN, HUMAN; POLYSACCHARIDE; PROTEASOME; PROTEIN BINDING; SERINE PROTEINASE INHIBITOR; TUMOR PROTEIN; UBIQUITIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DISEASE; CELL CULTURE; CELL INCLUSION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL PLASTICITY; NEUROPROTECTION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; WESTERN BLOTTING; ANIMAL; DEMYELINATING DISEASE; DISEASE MODEL; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; GENETICS; GLYCOSYLATION; METABOLISM; MUTATION; MYOCLONUS EPILEPSY; PROTEIN DEGRADATION; PROTEIN TRANSPORT; TRANSGENIC MOUSE;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; EPILEPSIES, MYOCLONIC; GLYCOSYLATION; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; LECTINS; MICE, TRANSGENIC; MUTATION; NEOPLASM PROTEINS; NEUROPEPTIDES; POLYSACCHARIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEOLYSIS; SERPINS; UBIQUITIN;

EID: 84903815342     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.04.002     Document Type: Article

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