Rag GTPases are cardioprotective by regulating lysosomal function

Nature Communications

Volumn 5, Issue , 2014, Pages

  Kim, Young Chul ^a   Park, Hyun Woo ^a   Sciarretta, Sebastiano ^b,c   Mo, Jung Soon ^a   Jewell, Jenna L ^a   Russell, Ryan C ^a   Wu, Xiaohui ^d   Sadoshima, Junichi ^b   Guan, Kun Liang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c IRCCS NEUROMED   (Italy)

^d FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAGA PROTEIN; RAGB PROTEIN; RECOMBINATION ACTIVATING GENE GUANOSINE TRIPHOSPHATE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIPROTEIN COMPLEX; RAGA PROTEIN, MOUSE; RAGB PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

AMINO ACID; ENZYME ACTIVITY; PHYSIOLOGICAL RESPONSE; PROTEIN; RODENT;

ACIDIFICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMEGALY; CARDIOMYOPATHY; CELL FUNCTION; CONTROLLED STUDY; HEART DISEASE; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HYPERTROPHIC CARDIOMYOPATHY; IN VIVO STUDY; LYSOSOME; LYSOSOME STORAGE DISEASE; MOUSE; NONHUMAN; PHYSIOLOGY; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE CELL; CARDIOMYOPATHY, HYPERTROPHIC; ENZYMOLOGY; FEMALE; GENETICS; HUMAN; KNOCKOUT MOUSE; MALE; METABOLISM;

ANIMALS; CARDIOMYOPATHY, HYPERTROPHIC; FEMALE; HUMANS; LYSOSOMES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOMERIC GTP-BINDING PROTEINS; MULTIPROTEIN COMPLEXES; MYOCYTES, CARDIAC; TOR SERINE-THREONINE KINASES;

EID: 84903795431     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5241     Document Type: Article

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