Leptin-promoted human extravillous trophoblast invasion is MMP14 dependent andrequires the cross talk between notch1 and PI3k/Akt signaling

Biology of Reproduction

Volumn 90, Issue 4, 2014, Pages

  Wang, Huayang ^a   Cheng, Huanhuan ^a   Shao, Qianqian ^a   Dong, Zhaogang ^a   Xie, Qi ^a   Zhao, Lei ^a   Wang, Qingjie ^a   Kong, Beihua ^a   Qu, Xun ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b Shandong University Nanshan Branch of Qilu Hospital   (China)

Author keywords

Extravillous trophoblasts; Invasion; Leptin; MMP14

Indexed keywords

LEPTIN; MATRIX METALLOPROTEINASE 14; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; AKT1 PROTEIN, HUMAN; MMP14 PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN;

ARTICLE; BIOTINYLATION; CELL INVASION ASSAY; EXTRAVILLOUS TROPHOBLAST; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TROPHOBLAST; CELL MOTION; CYTOLOGY; DRUG EFFECTS; FEMALE; FIRST TRIMESTER PREGNANCY; GENETICS; METABOLISM; PHYSIOLOGY; PREGNANCY; TRANSFORMED CELL LINE;

CELL LINE, TRANSFORMED; CELL MOVEMENT; FEMALE; HUMANS; LEPTIN; MATRIX METALLOPROTEINASE 14; PHOSPHATIDYLINOSITOL 3-KINASES; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR CROSS-TALK; RECEPTOR, NOTCH1; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TROPHOBLASTS;

EID: 84903775815     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.114876     Document Type: Article

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