MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development

EMBO Journal

Volumn 30, Issue 11, 2011, Pages 2281-2293

  Jin, Guoxiang ^a,b   Zhang, Fengju ^c   Chan, Kui Ming ^a   Xavier Wong, Hoi Leong ^a   Liu, Baohua ^a   Cheah, Kathryn S E ^a   Liu, Xinguang ^b   Mauch, Cornelia ^d   Liu, Depei ^e   Zhou, Zhongjun ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF COLOGNE   (Germany)

^e INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

B cell differentiation; Dll1; MT1 MMP; Notch signalling

Indexed keywords

DELTA LIKE 1 PROTEIN; MATRIX METALLOPROTEINASE 14; NOTCH RECEPTOR; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASE 14; MICE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 79957924074     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.136     Document Type: Article

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