Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors

Nature Neuroscience

Volumn 15, Issue 11, 2012, Pages 1547-1555

  Quintana, Albert ^a   Sanz, Elisenda ^b   Wang, Wengang ^c   Storey, Granville P ^c   Güler, Ali D ^a   Wanat, Matthew J ^b   Roller, Bryan A ^a   La Torre, Anna ^c   Amieux, Paul S ^b   McKnight, G Stanley ^b   Bamford, Nigel S ^c   Palmiter, Richard D ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 88; GLUTAMIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CORPUS STRIATUM; ELECTROPHYSIOLOGY; EXCITATION; GABAERGIC SYSTEM; IN VIVO STUDY; MENTAL DISEASE; MOTOR CONTROL; NERVE CELL; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; BENZYLAMINES; BIOPHYSICS; CELLS, CULTURED; CHROMONES; CORPUS STRIATUM; CUES; ELECTRIC STIMULATION; EMBRYO, MAMMALIAN; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MUTATION; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHINIC ACIDS; RECEPTORS, AMPA; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, GABA-B; ROTAROD PERFORMANCE TEST;

EID: 84868108590     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3239     Document Type: Article

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