HCV-induced immune responses influence the development of operational tolerance after liver transplantation in humans

Science Translational Medicine

Volumn 6, Issue 242, 2014, Pages

  Bohne, Felix ^a,b   Londoño, María Carlota ^a   Benítez, Carlos ^a   Miquel, Rosa ^a   Martínez Llordella, Marc ^c   Russo, Carolina ^d   Ortiz, Cecilia ^e   Bonaccorsi Riani, Eliano ^c   Brander, Christian ^f   Bauer, Tanja ^d   Protzer, Ulrike ^b   Jaeckel, Elmar ^g   Taubert, Richard ^g   Forns, Xavier ^a   Navasa, Miquel ^a   Berenguer, Marina ^e   Rimola, Antoni ^a   Lozano, Juan José ^h   Sánchez Fueyo, Alberto ^a,c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e UNIVERSITY OF VALENCIA   (Spain)

^f INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR; CXCL1 CHEMOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERCELLULAR ADHESION MOLECULE 1; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 7; INTERFERON REGULATORY FACTOR 9; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 8; JANUS KINASE 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PROGRAMMED DEATH 1 RECEPTOR; STAT1 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; VIRUS RNA; BIOLOGICAL MARKER; INTERFERON; LYMPHOCYTE ANTIGEN RECEPTOR; T-CELL RECEPTOR VDELTA2, HUMAN;

ADAPTIVE IMMUNITY; ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CELLULAR PARAMETERS; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CYTOKINE PRODUCTION; DRUG WITHDRAWAL; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GRAFT RECIPIENT; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; IRF1 GENE; IRF7 GENE; IRF9 GENE; ISG15 GENE; LIVER BIOPSY; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MALE; MEMORY T LYMPHOCYTE; OAS1 GENE; OAS2 GENE; OPERATIONAL TOLERANCE; PHASE 2 CLINICAL TRIAL (TOPIC); PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; UPREGULATION; V DELTA 1 V DELTA 2 T CELL RATIO; VIRUS LOAD; CLINICAL TRIAL; GRAFT REJECTION; HEPACIVIRUS; IMMUNITY; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; MIDDLE AGED; PHASE 2 CLINICAL TRIAL;

BIOMARKERS; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GENE EXPRESSION REGULATION; GRAFT REJECTION; HEPACIVIRUS; HUMANS; IMMUNE TOLERANCE; IMMUNITY; IMMUNOSUPPRESSION; INTERFERON TYPE I; LIVER TRANSPLANTATION; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA;

EID: 84903767450     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3008793     Document Type: Article

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