메뉴 건너뛰기




Volumn 15, Issue 7, 2014, Pages 11760-11772

Paeonol suppresses chondrosarcoma metastasis through up-regulation of miR-141 by modulating PKCδ and c-Src signaling pathway

Author keywords

Chondrosarcoma; Metastasis; miR 141; Paeonol

Indexed keywords

MICRORNA 141; PEONOL; PROTEIN KINASE C; ACETOPHENONE DERIVATIVE; MICRORNA; MIRN141 MICRORNA, HUMAN; PROTEIN KINASE C DELTA; PROTEIN TYROSINE KINASE;

EID: 84903745997     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150711760     Document Type: Article
Times cited : (36)

References (42)
  • 2
    • 84866481187 scopus 로고    scopus 로고
    • Molecular mechanisms of chondrosarcoma metastasis
    • Tang, C.H. Molecular mechanisms of chondrosarcoma metastasis. Biol. Med. 2012, 2, 92-98.
    • (2012) Biol. Med. , vol.2 , pp. 92-98
    • Tang, C.H.1
  • 3
    • 27644507899 scopus 로고    scopus 로고
    • RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion
    • Yuan, J.; Dutton, C.M.; Scully, S.P. RNAi mediated MMP-1 silencing inhibits human chondrosarcoma invasion. J. Orthop. Res. 2005, 23, 1467-1474.
    • (2005) J. Orthop. Res. , vol.23 , pp. 1467-1474
    • Yuan, J.1    Dutton, C.M.2    Scully, S.P.3
  • 4
    • 84893753312 scopus 로고    scopus 로고
    • The CCN family proteins: Modulators of bone development and novel targets in bone-associated tumors
    • Chen, P.C.; Cheng, H.C.; Yang, S.F.; Lin, C.W.; Tang, C.H. The CCN family proteins: Modulators of bone development and novel targets in bone-associated tumors. Biomed. Res. Int. 2014, 2014, 437096.
    • (2014) Biomed. Res. Int. , vol.2014 , pp. 437096
    • Chen, P.C.1    Cheng, H.C.2    Yang, S.F.3    Lin, C.W.4    Tang, C.H.5
  • 5
    • 84896081410 scopus 로고    scopus 로고
    • Novel strategies for the treatment of chondrosarcomas: Targeting integrins
    • Chen, J.C.; Fong, Y.C.; Tang, C.H. Novel strategies for the treatment of chondrosarcomas: Targeting integrins. Biomed. Res. Int. 2013, 2013, 396839.
    • (2013) Biomed. Res. Int. , vol.2013 , pp. 396839
    • Chen, J.C.1    Fong, Y.C.2    Tang, C.H.3
  • 6
    • 84866508432 scopus 로고    scopus 로고
    • Humans and cancer: An ongoing fight
    • Yin, M.C. Humans and cancer: An ongoing fight. Biol. Med. 2012, 2, 83.
    • (2012) Biol. Med. , vol.2 , pp. 83
    • Yin, M.C.1
  • 7
    • 80051645654 scopus 로고    scopus 로고
    • Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway
    • Liu, S.S.; Chen, X.M.; Zheng, H.X.; Shi, S.L.; Li, Y. Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway. J. Biomed. Sci. 2011, 18, 58.
    • (2011) J. Biomed. Sci. , vol.18 , pp. 58
    • Liu, S.S.1    Chen, X.M.2    Zheng, H.X.3    Shi, S.L.4    Li, Y.5
  • 8
    • 84860407637 scopus 로고    scopus 로고
    • IL-8 increases integrin expression and cell motility in human chondrosarcoma cells
    • Lee, C.Y.; Huang, C.Y.; Chen, M.Y.; Lin, C.Y.; Hsu, H.C.; Tang, C.H. IL-8 increases integrin expression and cell motility in human chondrosarcoma cells. J. Cell. Biochem. 2011, 112, 2549-2557.
    • (2011) J. Cell. Biochem. , vol.112 , pp. 2549-2557
    • Lee, C.Y.1    Huang, C.Y.2    Chen, M.Y.3    Lin, C.Y.4    Hsu, H.C.5    Tang, C.H.6
  • 13
    • 14544296126 scopus 로고    scopus 로고
    • Ductal carcinoma in situ of the breast and heparanase-1 expression: A molecular explanation for more aggressive subtypes
    • Maxhimer, J.B.; Pesce, C.E.; Stewart, R.A.; Gattuso, P.; Prinz, R.A.; Xu, X. Ductal carcinoma in situ of the breast and heparanase-1 expression: A molecular explanation for more aggressive subtypes. J. Am. Coll. Surg. 2005, 200, 328-335.
    • (2005) J. Am. Coll. Surg. , vol.200 , pp. 328-335
    • Maxhimer, J.B.1    Pesce, C.E.2    Stewart, R.A.3    Gattuso, P.4    Prinz, R.A.5    Xu, X.6
  • 14
    • 0026052321 scopus 로고
    • Synthesis of chondrocytic keratan sulphate-containing proteoglycans by human chondrosarcoma cells in long-term cell culture
    • Block, J.A.; Inerot, S.E.; Gitelis, S.; Kimura, J.H. Synthesis of chondrocytic keratan sulphate-containing proteoglycans by human chondrosarcoma cells in long-term cell culture. J. Bone Jt. Surg. Am. Vol. 1991, 73, 647-658.
    • (1991) J. Bone Jt. Surg. Am. Vol. , vol.73 , pp. 647-658
    • Block, J.A.1    Inerot, S.E.2    Gitelis, S.3    Kimura, J.H.4
  • 16
    • 78650051662 scopus 로고    scopus 로고
    • The CCL5/CCR5 axis promotes interleukin-6 production in human synovial fibroblasts
    • Tang, C.H.; Hsu, C.J.; Fong, Y.C. The CCL5/CCR5 axis promotes interleukin-6 production in human synovial fibroblasts. Arthritis Rheumatol. 2010, 62, 3615-3624.
    • (2010) Arthritis Rheumatol. , vol.62 , pp. 3615-3624
    • Tang, C.H.1    Hsu, C.J.2    Fong, Y.C.3
  • 17
    • 0041667974 scopus 로고    scopus 로고
    • Anti-inflammatory and analgesic effects of paeonol in carrageenan-evoked thermal hyperalgesia
    • Chou, T.C. Anti-inflammatory and analgesic effects of paeonol in carrageenan-evoked thermal hyperalgesia. Br. J. Pharmacol. 2003, 139, 1146-1152.
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 1146-1152
    • Chou, T.C.1
  • 18
    • 33846649645 scopus 로고    scopus 로고
    • Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-κB signaling pathways
    • Nizamutdinova, I.T.; Oh, H.M.; Min, Y.N.; Park, S.H.; Lee, M.J.; Kim, J.S.; Yean, M.H.; Kang, S.S.; Kim, Y.S.; Chang, K.C. Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-κB signaling pathways. Int. Immunopharmacol. 2007, 7, 343-350.
    • (2007) Int. Immunopharmacol. , vol.7 , pp. 343-350
    • Nizamutdinova, I.T.1    Oh, H.M.2    Min, Y.N.3    Park, S.H.4    Lee, M.J.5    Kim, J.S.6    Yean, M.H.7    Kang, S.S.8    Kim, Y.S.9    Chang, K.C.10
  • 19
    • 19644364143 scopus 로고    scopus 로고
    • Hypersialylation of β1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility
    • Seales, E.C.; Jurado, G.A.; Brunson, B.A.; Wakefield, J.K.; Frost, A.R.; Bellis, S.L. Hypersialylation of β1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility. Cancer Res. 2005, 65, 4645-4652.
    • (2005) Cancer Res. , vol.65 , pp. 4645-4652
    • Seales, E.C.1    Jurado, G.A.2    Brunson, B.A.3    Wakefield, J.K.4    Frost, A.R.5    Bellis, S.L.6
  • 21
  • 22
    • 67650716768 scopus 로고    scopus 로고
    • Paeonol exerts anti-angiogenic and anti-metastatic activities through downmodulation of Akt activation and inactivation of matrix metalloproteinases
    • Kim, S.A.; Lee, H.J.; Ahn, K.S.; Lee, E.O.; Choi, S.H.; Jung, S.J.; Kim, J.Y.; Baek, N.; Kim, S.H. Paeonol exerts anti-angiogenic and anti-metastatic activities through downmodulation of Akt activation and inactivation of matrix metalloproteinases. Biol. Pharm. Bull. 2009, 32, 1142-1147.
    • (2009) Biol. Pharm. Bull. , vol.32 , pp. 1142-1147
    • Kim, S.A.1    Lee, H.J.2    Ahn, K.S.3    Lee, E.O.4    Choi, S.H.5    Jung, S.J.6    Kim, J.Y.7    Baek, N.8    Kim, S.H.9
  • 23
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: Rationale, strategies and challenges
    • Garzon, R.; Marcucci, G.; Croce, C.M. Targeting microRNAs in cancer: Rationale, strategies and challenges. Nat. Rev. Drug Discov. 2010, 9, 775-789.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 25
    • 84894415230 scopus 로고    scopus 로고
    • hsa-miR-141 down-regulates TM4SF1 to inhibit pancreatic cancer cell invasion and migration
    • Xu, L.; Li, Q.; Xu, D.; Wang, Q.; An, Y.; Du, Q.; Zhang, J.; Zhu, Y.; Miao, Y. hsa-miR-141 down-regulates TM4SF1 to inhibit pancreatic cancer cell invasion and migration. Int. J. Oncol. 2014, 44, 459-466.
    • (2014) Int. J. Oncol. , vol.44 , pp. 459-466
    • Xu, L.1    Li, Q.2    Xu, D.3    Wang, Q.4    An, Y.5    Du, Q.6    Zhang, J.7    Zhu, Y.8    Miao, Y.9
  • 26
    • 84884259763 scopus 로고    scopus 로고
    • Berberine reduces the metastasis of chondrosarcoma by modulating the ανβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways
    • Wu, C.M.; Li, T.M.; Tan, T.W.; Fong, Y.C.; Tang, C.H. Berberine reduces the metastasis of chondrosarcoma by modulating the ανβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways. Evid. Based Complement. Altern. Med. 2013, 2013, 423164.
    • (2013) Evid. Based Complement. Altern. Med. , vol.2013 , pp. 423164
    • Wu, C.M.1    Li, T.M.2    Tan, T.W.3    Fong, Y.C.4    Tang, C.H.5
  • 27
    • 84884197563 scopus 로고    scopus 로고
    • AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma
    • Hsu, C.J.; Wu, M.H.; Chen, C.Y.; Tsai, C.H.; Hsu, H.C.; Tang, C.H. AMP-activated protein kinase activation mediates CCL3-induced cell migration and matrix metalloproteinase-2 expression in human chondrosarcoma. Cell Commun. Signal. 2013, 33, 68.
    • (2013) Cell Commun. Signal. , vol.33 , pp. 68
    • Hsu, C.J.1    Wu, M.H.2    Chen, C.Y.3    Tsai, C.H.4    Hsu, H.C.5    Tang, C.H.6
  • 28
    • 84898016402 scopus 로고    scopus 로고
    • Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells
    • Wu, M.H.; Huang, C.Y.; Lin, J.A.; Wang, S.W.; Peng, C.Y.; Cheng, H.C.; Tang, C.H. Endothelin-1 promotes vascular endothelial growth factor-dependent angiogenesis in human chondrosarcoma cells. Oncogene 2014, 33, 1725-1735.
    • (2014) Oncogene , vol.33 , pp. 1725-1735
    • Wu, M.H.1    Huang, C.Y.2    Lin, J.A.3    Wang, S.W.4    Peng, C.Y.5    Cheng, H.C.6    Tang, C.H.7
  • 31
    • 84870481545 scopus 로고    scopus 로고
    • Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKCδ/c-Src dependent signaling pathway
    • Yu, H.S.; Lin, T.H.; Tang, C.H. Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKCδ/c-Src dependent signaling pathway. Prostate 2013, 73, 89-100.
    • (2013) Prostate , vol.73 , pp. 89-100
    • Yu, H.S.1    Lin, T.H.2    Tang, C.H.3
  • 32
    • 33846048058 scopus 로고    scopus 로고
    • Transcription factors control invasion: AP-1 the first among equals
    • Ozanne, B.W.; Spence, H.J.; McGarry, L.C.; Hennigan, R.F. Transcription factors control invasion: AP-1 the first among equals. Oncogene 2007, 26, 1-10.
    • (2007) Oncogene , vol.26 , pp. 1-10
    • Ozanne, B.W.1    Spence, H.J.2    McGarry, L.C.3    Hennigan, R.F.4
  • 33
    • 84893846200 scopus 로고    scopus 로고
    • miR-141 suppresses proliferation and motility of gastric cancer cells by targeting HDGF
    • Chen, B.; Huang, T.; Jiang, J.; Lv, L.; Li, H.; Xia, S. miR-141 suppresses proliferation and motility of gastric cancer cells by targeting HDGF. Mol. Cell. Biochem. 2014, 388, 211-218.
    • (2014) Mol. Cell. Biochem. , vol.388 , pp. 211-218
    • Chen, B.1    Huang, T.2    Jiang, J.3    Lv, L.4    Li, H.5    Xia, S.6
  • 35
    • 77956919849 scopus 로고    scopus 로고
    • Prostaglandin E2/EP1 signaling pathway enhances intercellular adhesion molecule 1 (ICAM-1) expression and cell motility in oral cancer cells
    • Yang, S.F.; Chen, M.K.; Hsieh, Y.S.; Chung, T.T.; Hsieh, Y.H.; Lin, C.W.; Su, J.L.; Tsai, M.H.; Tang, C.H. Prostaglandin E2/EP1 signaling pathway enhances intercellular adhesion molecule 1 (ICAM-1) expression and cell motility in oral cancer cells. J. Biol. Chem. 2010, 285, 29808-29816.
    • (2010) J. Biol. Chem. , vol.285 , pp. 29808-29816
    • Yang, S.F.1    Chen, M.K.2    Hsieh, Y.S.3    Chung, T.T.4    Hsieh, Y.H.5    Lin, C.W.6    Su, J.L.7    Tsai, M.H.8    Tang, C.H.9
  • 36
    • 84872681084 scopus 로고    scopus 로고
    • Interleukin-6 induces vascular endothelial growth factor expression and promotes angiogenesis through apoptosis signal-regulating kinase 1 in human osteosarcoma
    • Tzeng, H.E.; Tsai, C.H.; Chang, Z.L.; Su, C.M.; Wang, S.W.; Hwang, W.L.; Tang, C.H. Interleukin-6 induces vascular endothelial growth factor expression and promotes angiogenesis through apoptosis signal-regulating kinase 1 in human osteosarcoma. Biochem. Pharmacol. 2013, 85, 531-540.
    • (2013) Biochem. Pharmacol. , vol.85 , pp. 531-540
    • Tzeng, H.E.1    Tsai, C.H.2    Chang, Z.L.3    Su, C.M.4    Wang, S.W.5    Hwang, W.L.6    Tang, C.H.7
  • 37
    • 77649313651 scopus 로고    scopus 로고
    • Cyclooxygenase-2 enhances α2β1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells
    • Liu, J.F.; Fong, Y.C.; Chang, C.S.; Huang, C.Y.; Chen, H.T.; Yang, W.H.; Hsu, C.J.; Jeng, L.B.; Chen, C.Y.; Tang, C.H. Cyclooxygenase-2 enhances α2β1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells. Mol. Cancer 2010, 9, 43.
    • (2010) Mol. Cancer , vol.9 , pp. 43
    • Liu, J.F.1    Fong, Y.C.2    Chang, C.S.3    Huang, C.Y.4    Chen, H.T.5    Yang, W.H.6    Hsu, C.J.7    Jeng, L.B.8    Chen, C.Y.9    Tang, C.H.10
  • 38
    • 84894375063 scopus 로고    scopus 로고
    • CTGF increases drug resistance to paclitaxel by upregulating survivin expression in human osteosarcoma cells
    • Tsai, H.C.; Huang, C.Y.; Su, H.L.; Tang, C.H. CTGF increases drug resistance to paclitaxel by upregulating survivin expression in human osteosarcoma cells. Biochim. Biophys. Acta 2014, 1843, 846-854.
    • (2014) Biochim. Biophys. Acta , vol.1843 , pp. 846-854
    • Tsai, H.C.1    Huang, C.Y.2    Su, H.L.3    Tang, C.H.4
  • 39
    • 84898622987 scopus 로고    scopus 로고
    • CCN2 enhances resistance to cisplatin-mediating cell apoptosis in human osteosarcoma
    • Tsai, H.C.; Huang, C.Y.; Su, H.L.; Tang, C.H. CCN2 enhances resistance to cisplatin-mediating cell apoptosis in human osteosarcoma. PLoS One 2014, 9, e90159.
    • (2014) PLoS One , vol.9
    • Tsai, H.C.1    Huang, C.Y.2    Su, H.L.3    Tang, C.H.4
  • 40
    • 84869046059 scopus 로고    scopus 로고
    • Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts
    • Huang, C.Y.; Chen, S.Y.; Tsai, H.C.; Hsu, H.C.; Tang, C.H. Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts. Arthritis Rheumatol. 2012, 64, 3344-3354.
    • (2012) Arthritis Rheumatol. , vol.64 , pp. 3344-3354
    • Huang, C.Y.1    Chen, S.Y.2    Tsai, H.C.3    Hsu, H.C.4    Tang, C.H.5
  • 41
    • 0031012054 scopus 로고    scopus 로고
    • Plant-derived anticancer agents
    • Pezzuto, J.M. Plant-derived anticancer agents. Biochem. Pharmacol. 1997, 53, 121-133.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 121-133
    • Pezzuto, J.M.1
  • 42
    • 84866514183 scopus 로고    scopus 로고
    • Anticancer potential of emodin
    • Hsu, S.C.; Chung, J.-G. Anticancer potential of emodin. BioMed 2012, 2, 108-116.
    • (2012) BioMed , vol.2 , pp. 108-116
    • Hsu, S.C.1    Chung, J.-G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.