-
1
-
-
0034085989
-
Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients
-
Bubendorf L, Schopfer A, Wagner U, et al. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol 2000;31:578-83.
-
(2000)
Hum Pathol
, vol.31
, pp. 578-583
-
-
Bubendorf, L.1
Schopfer, A.2
Wagner, U.3
-
2
-
-
0035996426
-
Clinical significance of pulmonary metastases in stage D2 prostate cancer patients
-
Nakamachi H, Suzuki H, Akakura K, et al. Clinical significance of pulmonary metastases in stage D2 prostate cancer patients. Prostate Cancer Prostatic Dis 2002;5:159-63.
-
(2002)
Prostate Cancer Prostatic Dis
, vol.5
, pp. 159-163
-
-
Nakamachi, H.1
Suzuki, H.2
Akakura, K.3
-
3
-
-
0033057962
-
Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
-
Vlodavsky I, Friedmann Y, Elkin M, et al. Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis. Nat Med 1999;5:793-802.
-
(1999)
Nat Med
, vol.5
, pp. 793-802
-
-
Vlodavsky, I.1
Friedmann, Y.2
Elkin, M.3
-
5
-
-
28444461805
-
Changes in secreted and cell associated proteoglycan synthesis during conversion of myoblasts to osteoblasts in response to bone morphogenetic protein-2: Role of decorin in cell response to BMP-2
-
Gutierrez J, Osses N, Brandan E. Changes in secreted and cell associated proteoglycan synthesis during conversion of myoblasts to osteoblasts in response to bone morphogenetic protein-2: Role of decorin in cell response to BMP-2. JCell Physiol 2005;206:58-67.
-
(2005)
JCell Physiol
, vol.206
, pp. 58-67
-
-
Gutierrez, J.1
Osses, N.2
Brandan, E.3
-
6
-
-
85044699738
-
Morphological study on cell-cell interaction between osteoclasts and osteoblasts
-
Nakamura H. Morphological study on cell-cell interaction between osteoclasts and osteoblasts. Kaibogaku Zasshi 2000;75:427-32.
-
(2000)
Kaibogaku Zasshi
, vol.75
, pp. 427-432
-
-
Nakamura, H.1
-
7
-
-
0033028789
-
Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis
-
Hulett MD, Freeman C, Hamdorf BJ, Baker RT, Harris MJ, Parish CR. Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis. Nat Med 1999;5:803-9.
-
(1999)
Nat Med
, vol.5
, pp. 803-809
-
-
Hulett, M.D.1
Freeman, C.2
Hamdorf, B.J.3
Baker, R.T.4
Harris, M.J.5
Parish, C.R.6
-
8
-
-
10044294056
-
Molecular properties and involvement of heparanase in cancer progression and mammary gland morphogenesis
-
Zcharia E, Metzger S, Chajek-Shaul T, et al. Molecular properties and involvement of heparanase in cancer progression and mammary gland morphogenesis. J Mammary Gland Biol Neoplasia 2001;6:311-22.
-
(2001)
J Mammary Gland Biol Neoplasia
, vol.6
, pp. 311-322
-
-
Zcharia, E.1
Metzger, S.2
Chajek-Shaul, T.3
-
9
-
-
0035405778
-
Heparanase as mediator of angiogenesis: Mode of action
-
Elkin M, Ilan N, Ishai-Michaeli R, et al. Heparanase as mediator of angiogenesis: mode of action. FASEB J 2001;15:1661-3.
-
(2001)
FASEB J
, vol.15
, pp. 1661-1663
-
-
Elkin, M.1
Ilan, N.2
Ishai-Michaeli, R.3
-
10
-
-
0034255845
-
Heparanase, a potential regulator of cell-matrix interactions
-
Dempsey LA, Brunn GJ, Platt JL. Heparanase, a potential regulator of cell-matrix interactions. Trends Biochem Sci 2000;25:349-51.
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 349-351
-
-
Dempsey, L.A.1
Brunn, G.J.2
Platt, J.L.3
-
11
-
-
0034827642
-
Heparanase protein and gene expression in bladder cancer
-
Gohji K, Okamoto M, Kitazawa S, et al. Heparanase protein and gene expression in bladder cancer. J Urol 2001;166:1286-90.
-
(2001)
J Urol
, vol.166
, pp. 1286-1290
-
-
Gohji, K.1
Okamoto, M.2
Kitazawa, S.3
-
12
-
-
14544296126
-
Ductal carcinoma in situ of the breast and heparanase-1 expression: A molecular explanation for more aggressive subtypes
-
Maxhimer JB, Pesce CE, Stewart RA, Gattuso P, Prinz RA, Xu X. Ductal carcinoma in situ of the breast and heparanase-1 expression: a molecular explanation for more aggressive subtypes. J Am Coll Surg 2005;200:328-35.
-
(2005)
J Am Coll Surg
, vol.200
, pp. 328-335
-
-
Maxhimer, J.B.1
Pesce, C.E.2
Stewart, R.A.3
Gattuso, P.4
Prinz, R.A.5
Xu, X.6
-
13
-
-
13744255420
-
Heparanase expression correlates with malignant potential in human colon cancer
-
Nobuhisa T, Naomoto Y, Ohkawa T, et al. Heparanase expression correlates with malignant potential in human colon cancer. J Cancer Res Clin Oncol 2005;131:229-37.
-
(2005)
J Cancer Res Clin Oncol
, vol.131
, pp. 229-237
-
-
Nobuhisa, T.1
Naomoto, Y.2
Ohkawa, T.3
-
14
-
-
18444385059
-
Heparanase: A key enzyme in invasion and metastasis of gastric carcinoma
-
Tang W, Nakamura Y, Tsujimoto M, et al. Heparanase: a key enzyme in invasion and metastasis of gastric carcinoma. Mod Pathol 2002;15:593-8.
-
(2002)
Mod Pathol
, vol.15
, pp. 593-598
-
-
Tang, W.1
Nakamura, Y.2
Tsujimoto, M.3
-
15
-
-
0030937093
-
Human prostate carcinoma cells produce extracellular heparanase
-
Kosir MA, Quinn CC, Zukowski KL, Grignon DJ, Ledbetter S. Human prostate carcinoma cells produce extracellular heparanase. J Surg Res 1997;67:98-105.
-
(1997)
J Surg Res
, vol.67
, pp. 98-105
-
-
Kosir, M.A.1
Quinn, C.C.2
Zukowski, K.L.3
Grignon, D.J.4
Ledbetter, S.5
-
16
-
-
0032854586
-
Degradation of basement membrane by prostate tumor heparanase
-
Kosir MA, Wang W, Zukowski KL, Tromp G, Barber J. Degradation of basement membrane by prostate tumor heparanase. J Surg Res 1999;81:42-7.
-
(1999)
J Surg Res
, vol.81
, pp. 42-47
-
-
Kosir, M.A.1
Wang, W.2
Zukowski, K.L.3
Tromp, G.4
Barber, J.5
-
17
-
-
19944432186
-
Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer
-
Ogishima T, Shiina H, Breault JE, et al. Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer. Clin Cancer Res 2005;11:1028-36.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1028-1036
-
-
Ogishima, T.1
Shiina, H.2
Breault, J.E.3
-
18
-
-
0142060014
-
Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissue
-
Stadlmann S, Moser PL, Pollheimer J, et al. Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissue. Eur J Cancer 2003;39:2229-33.
-
(2003)
Eur J Cancer
, vol.39
, pp. 2229-2233
-
-
Stadlmann, S.1
Moser, P.L.2
Pollheimer, J.3
-
19
-
-
3042637381
-
Processing and activation of latent heparanase occurs in lysosomes
-
Zetser A, Levy-Adam F, Kaplan V, et al. Processing and activation of latent heparanase occurs in lysosomes. J Cell Sci 2004;117:2249-58.
-
(2004)
J Cell Sci
, vol.117
, pp. 2249-2258
-
-
Zetser, A.1
Levy-Adam, F.2
Kaplan, V.3
-
20
-
-
0035800803
-
Expression pattern and secretion of human and chicken heparanase are determined by their signal peptide sequence
-
Goldshmidt O, Zcharia E, Aingorn H, et al. Expression pattern and secretion of human and chicken heparanase are determined by their signal peptide sequence. J Biol Chem 2001;276:29178-87.
-
(2001)
J Biol Chem
, vol.276
, pp. 29178-29187
-
-
Goldshmidt, O.1
Zcharia, E.2
Aingorn, H.3
-
21
-
-
0020640516
-
Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: Relationship to tumor cell metastasis
-
Vlodavsky I, Fuks Z, Bar-Ner M, Ariav Y, Schirrmacher V. Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis. Cancer Res1983;43:2704-11.
-
Cancer Res1983;43
, pp. 2704-2711
-
-
Vlodavsky, I.1
Fuks, Z.2
Bar-Ner, M.3
Ariav, Y.4
Schirrmacher, V.5
-
22
-
-
0023187867
-
A rapid in vitro assay for quantitating the invasive potential of tumor cells
-
Albini A, Iwamoto Y, Kleinman HK, et al. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 1987;47:3239-45.
-
(1987)
Cancer Res
, vol.47
, pp. 3239-3245
-
-
Albini, A.1
Iwamoto, Y.2
Kleinman, H.K.3
-
23
-
-
4344598247
-
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis
-
Edovitsky E, Elkin M, Zcharia E, Peretz T, Vlodavsky I. Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis. J Natl Cancer Inst 2004;96:1219-30.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1219-1230
-
-
Edovitsky, E.1
Elkin, M.2
Zcharia, E.3
Peretz, T.4
Vlodavsky, I.5
-
24
-
-
0042707678
-
Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease
-
Bendre MS, Montague DC, Peery T, Akel NS, Gaddy D, Suva LJ. Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. Bone 2003;33:28-37.
-
(2003)
Bone
, vol.33
, pp. 28-37
-
-
Bendre, M.S.1
Montague, D.C.2
Peery, T.3
Akel, N.S.4
Gaddy, D.5
Suva, L.J.6
-
25
-
-
33646430296
-
Role of endothelial heparanase in delayed-type hypersensitivity
-
Edovitsky E, Lerner I, Zcharia E, Peretz T, Vlodavsky I, Elkin M. Role of endothelial heparanase in delayed-type hypersensitivity. Blood 2006;107:3609-16.
-
(2006)
Blood
, vol.107
, pp. 3609-3616
-
-
Edovitsky, E.1
Lerner, I.2
Zcharia, E.3
Peretz, T.4
Vlodavsky, I.5
Elkin, M.6
-
26
-
-
17144396758
-
Heparanase regulates murine hair growth
-
Zcharia E, Philp D, Edovitsky E, et al. Heparanase regulates murine hair growth. Am J Pathol 2005;166:999-1008.
-
(2005)
Am J Pathol
, vol.166
, pp. 999-1008
-
-
Zcharia, E.1
Philp, D.2
Edovitsky, E.3
-
27
-
-
0015950349
-
Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging
-
Gleason DF, Mellinger GT. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J Urol 1974;111:58-64.
-
(1974)
J Urol
, vol.111
, pp. 58-64
-
-
Gleason, D.F.1
Mellinger, G.T.2
-
28
-
-
12544252991
-
Cell lines used in prostate cancer research: A compendium of old and new lines-part 1
-
Sobel RE, Sadar MD. Cell lines used in prostate cancer research: a compendium of old and new lines-part 1. J Urol 2005;173:342-59.
-
(2005)
J Urol
, vol.173
, pp. 342-359
-
-
Sobel, R.E.1
Sadar, M.D.2
-
29
-
-
0344645651
-
Cell surface expression and secretion of heparanase-markedly promote tumor angiogenesis and metastasis
-
Goldshmidt O, Zcharia E, Abramovitch R, et al. Cell surface expression and secretion of heparanase-markedly promote tumor angiogenesis and metastasis. Proc Natl Acad Sci U S A 2002;3:3.
-
(2002)
Proc Natl Acad Sci U S A
, vol.3
, pp. 3
-
-
Goldshmidt, O.1
Zcharia, E.2
Abramovitch, R.3
-
30
-
-
0035875082
-
Heparanase expression in primary and metastatic pancreatic cancer
-
Koliopanos A, Friess H, Kleeff J, et al. Heparanase expression in primary and metastatic pancreatic cancer. Cancer Res 2001;61:4655-9.
-
(2001)
Cancer Res
, vol.61
, pp. 4655-4659
-
-
Koliopanos, A.1
Friess, H.2
Kleeff, J.3
-
31
-
-
33846519554
-
Heparanase expression correlates with poor survival in metastatic ovarian carcinoma
-
Davidson B, Shafat I, Risberg B, et al. Heparanase expression correlates with poor survival in metastatic ovarian carcinoma. Gynecol Oncol 2007;104:311-9.
-
(2007)
Gynecol Oncol
, vol.104
, pp. 311-319
-
-
Davidson, B.1
Shafat, I.2
Risberg, B.3
-
32
-
-
32344434119
-
An ELISA method for the detection and quantification of human heparanase
-
Shafat I, Zcharia E, Nisman B, et al. An ELISA method for the detection and quantification of human heparanase. Biochem Biophys Res Commun 2006;341:958-63.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 958-963
-
-
Shafat, I.1
Zcharia, E.2
Nisman, B.3
-
33
-
-
0001384041
-
Involvement of the extracellular matrix, heparan sulphate proteoglycans, and heparan sulphate degrading enzymes in angiogenesis and metastasis
-
Bicknell R, Ferrara N, editors, Oxford: Oxford University Press;
-
Vlodavsky I. Involvement of the extracellular matrix, heparan sulphate proteoglycans, and heparan sulphate degrading enzymes in angiogenesis and metastasis. In: Bicknell R, Ferrara N, editors. Tumour angiogenesis. Oxford: Oxford University Press; 1997. p.125-40.
-
(1997)
Tumour angiogenesis
, pp. 125-140
-
-
Vlodavsky, I.1
-
34
-
-
31544436071
-
Elevated serum heparanase-1 levels in patients with pancreatic carcinoma are associated with poor survival
-
Quiros RM, Rao G, Plate J, et al. Elevated serum heparanase-1 levels in patients with pancreatic carcinoma are associated with poor survival. Cancer 2006;106:532-40.
-
(2006)
Cancer
, vol.106
, pp. 532-540
-
-
Quiros, R.M.1
Rao, G.2
Plate, J.3
-
35
-
-
11344267803
-
Prostate cancer bone metastases promote both osteolytic and osteoblastic activity
-
Keller ET, Brown J. Prostate cancer bone metastases promote both osteolytic and osteoblastic activity. J Cell Biochem 2004;91:718-29.
-
(2004)
J Cell Biochem
, vol.91
, pp. 718-729
-
-
Keller, E.T.1
Brown, J.2
-
36
-
-
0031923741
-
Comparison of markers of bone formation and resorption in prostate cancer patients to predict bone metastasis
-
Akimoto S, Furuya Y, Akakura K, Ito H. Comparison of markers of bone formation and resorption in prostate cancer patients to predict bone metastasis. Endocr J 1998;45:97-104.
-
(1998)
Endocr J
, vol.45
, pp. 97-104
-
-
Akimoto, S.1
Furuya, Y.2
Akakura, K.3
Ito, H.4
-
37
-
-
0023128529
-
Biochemical and histological evidence that carcinoma of the prostate is associated with increased bone resorption
-
Percival RC, Urwin GH, Harris S, et al. Biochemical and histological evidence that carcinoma of the prostate is associated with increased bone resorption. Eur J Surg Oncol 1987;13:41-9.
-
(1987)
Eur J Surg Oncol
, vol.13
, pp. 41-49
-
-
Percival, R.C.1
Urwin, G.H.2
Harris, S.3
-
38
-
-
0032102963
-
Total and regional bone mass and biochemical markers of bone remodeling in metastatic prostate cancer
-
Revilla M, Arribas I, Sanchez-Chapado M, Villa LF, Bethencourt F, Rico H. Total and regional bone mass and biochemical markers of bone remodeling in metastatic prostate cancer. Prostate 1998;35:243-7.
-
(1998)
Prostate
, vol.35
, pp. 243-247
-
-
Revilla, M.1
Arribas, I.2
Sanchez-Chapado, M.3
Villa, L.F.4
Bethencourt, F.5
Rico, H.6
-
39
-
-
0033962103
-
Markers of bone turnover for the management of patients with bone metastases from prostate cancer
-
Garnero P, Buchs N, Zekri J, Rizzoli R, Coleman RE, Delmas PD. Markers of bone turnover for the management of patients with bone metastases from prostate cancer. Br J Cancer 2000;82:858-64.
-
(2000)
Br J Cancer
, vol.82
, pp. 858-864
-
-
Garnero, P.1
Buchs, N.2
Zekri, J.3
Rizzoli, R.4
Coleman, R.E.5
Delmas, P.D.6
-
40
-
-
33644863802
-
Heparanase promotes growth, angiogenesis and survival of primary breast tumors
-
Cohen I, Pappo O, Elkin M, et al. Heparanase promotes growth, angiogenesis and survival of primary breast tumors. Int J Cancer 2006;118:1609-17.
-
(2006)
Int J Cancer
, vol.118
, pp. 1609-1617
-
-
Cohen, I.1
Pappo, O.2
Elkin, M.3
-
41
-
-
21344452789
-
Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases
-
Kelly T, Suva LJ, Huang Y, et al. Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases. Cancer Res 2005;65:5778-84.
-
(2005)
Cancer Res
, vol.65
, pp. 5778-5784
-
-
Kelly, T.1
Suva, L.J.2
Huang, Y.3
-
42
-
-
0347473795
-
Heparanase mRNA expression during fracture repair in mice
-
Saijo M, Kitazawa R, Nakajima M, Kurosaka M, Maeda S, Kitazawa S. Heparanase mRNA expression during fracture repair in mice. Histochem Cell Biol 2003;120:493-503.
-
(2003)
Histochem Cell Biol
, vol.120
, pp. 493-503
-
-
Saijo, M.1
Kitazawa, R.2
Nakajima, M.3
Kurosaka, M.4
Maeda, S.5
Kitazawa, S.6
-
43
-
-
0037711133
-
Heparanase mediates cell adhesion independent of its enzymatic activity
-
Goldshmidt O, Zcharia E, Cohen M, et al. Heparanase mediates cell adhesion independent of its enzymatic activity. FASEB J 2003;17:1015-25.
-
(2003)
FASEB J
, vol.17
, pp. 1015-1025
-
-
Goldshmidt, O.1
Zcharia, E.2
Cohen, M.3
-
44
-
-
34247637147
-
Heparanase: A target for drug discovery in cancer and inflammation
-
McKenzie EA. Heparanase: a target for drug discovery in cancer and inflammation. Br J Pharmacol 2007;151:1-14.
-
(2007)
Br J Pharmacol
, vol.151
, pp. 1-14
-
-
McKenzie, E.A.1
-
45
-
-
33746552708
-
Development of heparanase inhibitors for anti-cancer therapy
-
Miao HQ, Liu H, Navarro E, Kussie P, Zhu Z. Development of heparanase inhibitors for anti-cancer therapy. Curr Med Chem 2006;13:2101-11.
-
(2006)
Curr Med Chem
, vol.13
, pp. 2101-2111
-
-
Miao, H.Q.1
Liu, H.2
Navarro, E.3
Kussie, P.4
Zhu, Z.5
-
46
-
-
3242712146
-
The development of inhibitors of heparanase, a key enzyme involved in tumour metastasis, angiogenesis and inflammation
-
Ferro V, Hammond E, Fairweather JK. The development of inhibitors of heparanase, a key enzyme involved in tumour metastasis, angiogenesis and inflammation. Mini Rev Med Chem 2004;4:693-702.
-
(2004)
Mini Rev Med Chem
, vol.4
, pp. 693-702
-
-
Ferro, V.1
Hammond, E.2
Fairweather, J.K.3
|