Paeonol suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells by blocking p38, ERK and nuclear factor-κB signaling pathways

International Immunopharmacology

Volumn 7, Issue 3, 2007, Pages 343-350

  Nizamutdinova, Irina Tsoy ^a   Oh, Hwa Min ^a   Min, Young Nam ^a   Park, Sun Hee ^a   Lee, Min Joo ^a   Kim, Ju Sun ^b   Yean, Min Hye ^b   Kang, Sam Sik ^b   Kim, Yeong Shik ^b   Chang, Ki Churl ^a   Kim, Hye Jung ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Atherosclerosis; Intercellular adhesion molecule 1; MAP kinases; NF kappaB; Paeonol; Tumor necrosis factor alpha

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEONOL; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL ADHESION; CELL STIMULATION; CELL STRAIN U937; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

ACETOPHENONES; ATHEROSCLEROSIS; CELL ADHESION; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; I-KAPPA B PROTEINS; INTERCELLULAR ADHESION MOLECULE-1; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS;

EID: 33846649645     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2006.11.004     Document Type: Article

References (38)

1. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 340 (1999) 115-126
2. Glass C.K., and Witztum J.L. Atherosclerosis the road head. Cell 104 (2001) 503-516
3. Blankenberg S., Barbaux S., and Tiret L. Adhesion molecules and atherosclerosis. Atherosclerosis 170 (2003) 191-203
4. Leeuwenberg J.F., Smeets E.F., Neefjes J.J., Shaffer M.A., Cinek T., Jeunhommer T.M., et al. E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro. Immunology 77 (1992) 543-549
5. Chuang K.P., Huang Y.F., Hsu Y.L., Liu H.S., Chen H.C., and Shieh C.C. Ligation of lymphocyte function-associated antigen-1 on monocytes decreases very late antigen-4-mediated adhesion through a reactive oxygen species-dependent pathway. Blood 104 (2004) 4046-4053
6. Collins R.G., Velji R., Guevara N.V., Hicks M.J., Chan L., and Beaudet A.L. P-selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice. J Exp Med 191 (2000) 189-194
7. Wong C.K., Wang C.B., Li M.L., Ip W.K., Tian Y.P., and Lam C.W. Induction of adhesion molecules upon the interaction between eosinophils and bronchial epithelial cells: Involvement of p38 MAPK and NF-kappaB. Int Immunopharmacol 6 (2006) 1859-1871
8. Matsukura S., Kokubu F., Kurokawa M., Kawaguchi M., Ieki K., Kuga H., et al. Synthetic double-stranded RNA induces multiple genes related to inflammation through Toll-like receptor 3 depending on NF-kappaB and/or IRF-3 in airway epithelial cells. Clin Exp Allergy 36 (2006) 1049-1062
9. Pfeffer K., Matsuyama T., Kunding T.M., Wakeham A., Kishihara K., Shahinian A., et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73 (1993) 457-467
10. Pober J.S., and Cotran R.S. Cytokine and endothelial cell biology. Physiol Rev 70 (1990) 427-451
11. Springer T.A. Traffic signal for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76 (1994) 301-314
12. Modur V., Zimmerman G.A., Prescott S.M., and McIntyre T.M. Endothelial cell inflammatory responses to tumor necrosis factor alpha, ceramide-dependent and -independent mitogen-activated protein kinase cascades. J Biol Chem 271 (1996) 13094-13102
13. Brett J., Gerlach H., Nawroth P., Steinberg S., Godman G., and Stern D. Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins. J Exp Med 169 (1989) 1977-1991
14. Knauer M.F., Longmuir K.J., Yamomoto R.S., Fitzgerald T.P., and Granger G.A. Mechanism of human lymphotoxin and tumor necrosis factor induced destruction of cells in vitro: phospholipase activation and deacylation of specific-membrane phospholipids. J Cell Physiol 142 (1990) 469-479
15. 2+. Proc Natl Acad Sci USA 87 (1990) 9472-9476
16. Kolesnik R., and Golde D.W. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77 (1994) 325-328
17. Berk B.C., Abe J.I., Min W., Surapisitchat J., and Yan C. Endothelial atheroprotective and anti-inflammatory mechanisms. Ann N Y Acad Sci 947 (2001) 93-109
18. Surapisitchat J., Hoefen R.J., Pi X., Yoshizumi M., Yan C., and Berk B.C. Fluid shear stress inhibits TNF-α activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: inhibitory crosstalk among MAPK family members. Proc Natl Acad Sci USA 98 (2001) 6476-6481
19. Hirai A., Terano T., Hamazaki T., Sajiki J., Saito H., Tahara K., et al. Studies on the mechanisms of antiaggregatory effect of Mautan cortex. Thromb Res 31 (1983) 29-40
20. Zhang H.Y., Ge N., and Zhang Z.Y. Theoretical elucidation of activity differences of five phenolic antioxidants. Zhongguo Yao Li Xue Bao 20 (1999) 363-366
21. Kang S.S., Shin K.H., and Chi H.J. Galloylpaeoniflorin, a new acylated monoterpene glucoside from paeony root. Arch Pharm Res 14 (1991) 52-54
22. Jaffe E.A., Nachman R.L., Becker C.G., and Minick C.R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52 (1973) 2745-2756
23. Ji C., Kozak K.R., and Marnett L.J. IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal. J Biol Chem 276 (2001) 18223-18228
24. Kim H.J., Tsoy I., Park J.M., Chung J.I., Shin S.C., and Chang K.C. Anthocyanins from soybean seed coat inhibit the expression of TNF-alpha-induced genes associated with ischemia/reperfusion in endothelial cell by NF-kappaB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo. FEBS Lett 580 (2006) 1391-1397
25. Roebuck K.A., and Finnegan A. Regulation of intercellular adhesion molecule-1 (CD54) gene expression. J Leukoc Biol 66 (1999) 876-888
26. Che W., Lener-Marmarosh N., Huang Q., Osawa M., Ohta S., Yushizumi M., et al. Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-α-induced c-Jun and NF-κB activation and adhesion molecule expression. Circ Res 90 (2002) 1222-1230
27. Ahmad M., Zhang Y., Parpharalambus C., and Alexander R.W. Role of isoprenylcysteine carboxyl methyltransferase in tumor necrosis factor-α stimulation of expression of vascular cell adhesion molecule-1 in endothelial cells. Arterioscler Thromb Vasc Biol 22 (2002) 759-764
28. Lenardo M.J., and Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58 (1989) 227-229
29. Beg A.A., Finco T.S., Nantermet P.V., and Baldwin A.S. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: a mechanism for NF-κB activation. Mol Cell Biol 13 (1993) 3301-3310
30. Angel P., and Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072 (1991) 129-157
31. Xu X.S., Vanderziel C., Bennett C.F., and Monia B.P. A role for c-Raf kinase and Ha-Ras in cytokine-mediated induction of cell adhesion molecules. J Biol Chem 273 (1998) 33228-33230
32. Nwariaku F.E., Chang J., Zhu X., Liu Z., Duffy S.L., Halaihel N.H., et al. The role of p38 map kinase in tumor necrosis factor-induced redistribution of vascular endothelial cadherin and increased endothelial permeability. Shock 18 (2002) 82-85
33. Knebel A., Rahmsdorf H.J., Ullrich A., and Herrich P. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO J 15 (1996) 5314-5325
34. Corda S., Laplace C., Vicaut E., and Derateau J. Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-α is mediated by ceramide. Am J Respir Cell Mol Biol 24 (2001) 762-768
35. Tominaga H., Kobayashi Y., Goto T., Kasemura K., and Nomura M. DPPH radical-scavenging effect of several phenylpropanoid compounds and their glycoside derivatives. Yakugaku Zasshi 125 (2005) 371-375
36. Dai M., Liu Q.Y., Gu C.G., and Zhang H.Y. Inhibitory effect of paeonol on lipid peroxidational reaction and oxidational decorate of low density lipoprotein. Zhongguo Zhong Yao Za Zhi 25 (2000) 625-627
37. Dai M., Zhi X., Peng D., and Liu Q. Inhibitory effect of paeonol on experimental atherosclerosis in quails. Zhongguo Zhong Yao Za Zhi 24 (1999) 488-490 [512]
38. Zhang W.G., and Zhang Z.S. Anti-ischemia reperfusion damage and anti-lipid peroxidation effects of paeonol in rat heart. Yao Xue Xue Bao 29 (1994) 145-148