-
1
-
-
0037072453
-
Multiple atherosclerotic plaque rupture in acute coronary syndrome: A three-vessel intravascular ultrasound study
-
Rioufol, G. et al. Multiple atherosclerotic plaque rupture in acute coronary syndrome: a three-vessel intravascular ultrasound study. Circulation 106, 804-808 (2002).
-
(2002)
Circulation
, vol.106
, pp. 804-808
-
-
Rioufol, G.1
-
2
-
-
34250355761
-
Functional ultrastructure of the vascular endothelium: Changes in various pathologies
-
Simionescu, M. & Antohe, F. Functional ultrastructure of the vascular endothelium: changes in various pathologies. Handb. Exp. Pharmacol. 176 Pt 1, 41-69 (2006).
-
(2006)
Handb. Exp. Pharmacol.
, vol.176 PART 1
, pp. 41-69
-
-
Simionescu, M.1
Antohe, F.2
-
3
-
-
57749182237
-
Vascular endothelium in atherosclerosis
-
Sima, A. V., Stancu, C. S. & Simionescu, M. Vascular endothelium in atherosclerosis. Cell. Tissue. Res. 335, 191-203 (2009).
-
(2009)
Cell. Tissue. Res.
, vol.335
, pp. 191-203
-
-
Sima, A.V.1
Stancu, C.S.2
Simionescu, M.3
-
4
-
-
84892914260
-
The vascular endothelium and human diseases
-
Rajendran, P. et al. The Vascular Endothelium and Human Diseases. Int. J. Biol. Sci. 9, 1057-1069 (2013).
-
(2013)
Int. J. Biol. Sci.
, vol.9
, pp. 1057-1069
-
-
Rajendran, P.1
-
5
-
-
84555187749
-
Mammalian target of rapamycin: A signaling kinase for every aspect of cellular life
-
Weichhart, T. Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life. Methods. Mol. Biol. 821, 1-14 (2012).
-
(2012)
Methods. Mol. Biol.
, vol.821
, pp. 1-14
-
-
Weichhart, T.1
-
6
-
-
84859778293
-
MTORsignaling in growth control and disease
-
Laplante, M. & Sabatini, D. M.mTORsignaling in growth control and disease. Cell 149, 274-293 (2012).
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
7
-
-
33746090919
-
Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes
-
DOI 10.1016/j.yjmcc.2006.04.014, PII S0022282806005268
-
Khan, S. et al. Rapamycin confers preconditioning-like protection against isc (Pubitemid 44080210)
-
(2006)
Journal of Molecular and Cellular Cardiology
, vol.41
, Issue.2
, pp. 256-264
-
-
Khan, S.A.1
Salloum, F.2
Das, A.3
Xi, L.4
Vetrovec, G.W.5
Kukreja, R.C.6
-
8
-
-
84873246975
-
Impact of gender on clinical outcomes after mTOR-inhibitor drug-eluting stent implantation in patients with first manifestation of ischaemic heart disease
-
Niccoli, G. et al. Impact of gender on clinical outcomes after mTOR-inhibitor drug-eluting stent implantation in patients with first manifestation of ischaemic heart disease. Eur. J. Prev. Cardiol. 19, 914-926 (2012).
-
(2012)
Eur. J. Prev. Cardiol.
, vol.19
, pp. 914-926
-
-
Niccoli, G.1
-
9
-
-
84883864620
-
Tailoring mTOR-based therapy: Molecular evidence and clinical challenges
-
Santulli, G. & Totary-Jain,H. Tailoring mTOR-based therapy: molecular evidence and clinical challenges. Pharmacogenomics 14, 1517-1526 (2013).
-
(2013)
Pharmacogenomics
, vol.14
, pp. 1517-1526
-
-
Santulli, G.1
Totary-Jain, H.2
-
10
-
-
0038585135
-
Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice
-
DOI 10.1034/j.1600-6143.2003.00094.x
-
Elloso, M. M. et al. Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice. Am. J. Transplant. 3, 562-569 (2003). (Pubitemid 36612839)
-
(2003)
American Journal of Transplantation
, vol.3
, Issue.5
, pp. 562-569
-
-
Elloso, M.M.1
Azrolan, N.2
Sehgal, S.N.3
Hsu, P.-L.4
Phiel, K.L.5
Kopec, C.A.6
Basso, M.D.7
Adelman, S.J.8
-
11
-
-
33846815137
-
Selective clearance of macrophages in atherosclerotic plaques by autophagy
-
DOI 10.1016/j.jacc.2006.09.047, PII S0735109706028889
-
Verheye, S. et al. Selective clearance of macrophages in atherosclerotic plaques by autophagy. J. Am. Coll. Cardiol. 49, 706-715 (2007). (Pubitemid 46205042)
-
(2007)
Journal of the American College of Cardiology
, vol.49
, Issue.6
, pp. 706-715
-
-
Verheye, S.1
Martinet, W.2
Kockx, M.M.3
Knaapen, M.W.M.4
Salu, K.5
Timmermans, J.-P.6
Ellis, J.T.7
Kilpatrick, D.L.8
De Meyer, G.R.Y.9
-
12
-
-
84870584445
-
Drug-induced macrophage autophagy in atherosclerosis: For better or worse?
-
Martinet, W. et al. Drug-induced macrophage autophagy in atherosclerosis: for better or worse? Basic. Res. Cardiol. 108, 321 (2013).
-
(2013)
Basic. Res. Cardiol.
, vol.108
, pp. 321
-
-
Martinet, W.1
-
13
-
-
74549117768
-
Rapamycin promotes arterial thrombosis in vivo: Implications for everolimus and zotarolimus eluting stents
-
Camici, G. G. et al. Rapamycin promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents. Eur. Heart. J. 31, 236-242 (2010).
-
(2010)
Eur. Heart. J.
, vol.31
, pp. 236-242
-
-
Camici, G.G.1
-
14
-
-
33746929488
-
MTOR Inhibition induces endothelial progenitor cell death
-
DOI 10.1111/j.1600-6143.2006.01433.x
-
Miriuka, S. G. et al. mTOR inhibition induces endothelial progenitor cell death. Am. J. Transplant. 6, 2069-2079 (2006). (Pubitemid 44199541)
-
(2006)
American Journal of Transplantation
, vol.6
, Issue.9
, pp. 2069-2079
-
-
Miriuka, S.G.1
Rao, V.2
Peterson, M.3
Tumiati, L.4
Delgado, D.H.5
Mohan, R.6
Ramzy, D.7
Stewart, D.8
Ross, H.J.9
Waddell, T.K.10
-
15
-
-
84862726562
-
Cardiovascular disease and mTOR signaling
-
Chong, Z. Z., Shang, Y. C. & Maiese, K. Cardiovascular disease and mTOR signaling. Trends. Cardiovasc. Med. 21, 151-155 (2011).
-
(2011)
Trends. Cardiovasc. Med.
, vol.21
, pp. 151-155
-
-
Chong, Z.Z.1
Shang, Y.C.2
Maiese, K.3
-
16
-
-
0036275356
-
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR) -dependent signaling
-
DOI 10.1096/fj.01-0658com
-
Humar, R., Kiefer, F. N., Berns, H., Resink, T. J. & Battegay, E. J. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)- dependent signaling. FASEB. J. 16, 771-780 (2002). (Pubitemid 34615125)
-
(2002)
FASEB Journal
, vol.16
, Issue.8
, pp. 771-780
-
-
Humar, R.O.K.1
Kiefer, F.N.2
Berns, H.3
Resink, T.J.4
Battegay, E.J.5
-
17
-
-
37549006759
-
Both senescence and apoptosis induced by deprivation of growth factors were inhibited by a novel butyrolactone derivative through depressing integrin beta4 in vascular endothelial cells
-
Wang, W. et al. Both senescence and apoptosis induced by deprivation of growth factors were inhibited by a novel butyrolactone derivative through depressing integrin beta4 in vascular endothelial cells. Endothelium 14, 325-332 (2007).
-
(2007)
Endothelium
, vol.14
, pp. 325-332
-
-
Wang, W.1
-
18
-
-
49049088110
-
A novel butyrolactone derivative inhibited smooth muscle cell migration and proliferation and maintained endothelial cell functions through selectively affecting Na K-ATPase activity and mitochondria membrane potential during in vitro angiogenesis
-
Meng, N. et al. A novel butyrolactone derivative inhibited smooth muscle cell migration and proliferation and maintained endothelial cell functions through selectively affecting Na, K-ATPase activity and mitochondria membrane potential during in vitro angiogenesis. J. Cell. Biochem. 104, 2123-2130 (2008).
-
(2008)
J. Cell. Biochem.
, vol.104
, pp. 2123-2130
-
-
Meng, N.1
-
19
-
-
65949095200
-
Protective effects of a synthesized butyrolactone derivative against chloroquine-induced autophagic vesicle accumulation and the disturbance of mitochondrial membrane potential and Na1,K1-ATPase activity in vascular endothelial cells
-
Huang, B. et al. Protective effects of a synthesized butyrolactone derivative against chloroquine-induced autophagic vesicle accumulation and the disturbance of mitochondrial membrane potential and Na1,K1-ATPase activity in vascular endothelial cells. Chem. Res. Toxicol. 22, 471-475 (2009).
-
(2009)
Chem. Res. Toxicol.
, vol.22
, pp. 471-475
-
-
Huang, B.1
-
20
-
-
84855595493
-
Abutyrolactone derivative suppressed lipopolysaccharide-induced autophagic injury through inhibiting the autoregulatory loop of p8 and p53 in vascular endothelial cells
-
Meng, N. et al. Abutyrolactone derivative suppressed lipopolysaccharide- induced autophagic injury through inhibiting the autoregulatory loop of p8 and p53 in vascular endothelial cells. Int. J. Biochem. Cell. Bio. 44, 311-319 (2012).
-
(2012)
Int. J. Biochem. Cell. Bio.
, vol.44
, pp. 311-319
-
-
Meng, N.1
-
21
-
-
84863011390
-
Butyrolactone derivative 3-benzyl-5-((2-nitrophenoxy) methyl)- dihydrofuran-2(3H)-one protects against amyloid-beta peptides-induced cytotoxicity in PC12 cells
-
Yang, S. et al. Butyrolactone derivative 3-benzyl-5-((2-nitrophenoxy) methyl)- dihydrofuran-2(3H)-one protects against amyloid-beta peptides-induced cytotoxicity in PC12 cells. J. Alzheimers. Dis. 28, 345-356 (2012).
-
(2012)
J. Alzheimers. Dis.
, vol.28
, pp. 345-356
-
-
Yang, S.1
-
22
-
-
84903601682
-
Identification of a novelmTORactivator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells
-
Ge,D. et al. Identification of a novelmTORactivator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells. Autophagy 10, 957-971 (2014).
-
(2014)
Autophagy
, vol.10
, pp. 957-971
-
-
Ge, D.1
-
23
-
-
67549110195
-
A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy
-
Mercer, C. A., Kaliappan, A. & Dennis, P. B. A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy. Autophagy 5, 649-662 (2009).
-
(2009)
Autophagy
, vol.5
, pp. 649-662
-
-
Mercer, C.A.1
Kaliappan, A.2
Dennis, P.B.3
-
24
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1- Atg13-FIP200 complex required for autophagy
-
Hosokawa, N. et al. Nutrient-dependent mTORC1 association with the ULK1- Atg13-FIP200 complex required for autophagy. Mol. Biol. Cell. 20, 1981-1991 (2009).
-
(2009)
Mol. Biol. Cell.
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
-
25
-
-
84872527628
-
MTOR is a key modulator of ageing and age-related disease
-
Johnson, S. C., Rabinovitch, P. S. & Kaeberlein, M. mTOR is a key modulator of ageing and age-related disease. Nature 493, 338-345 (2013).
-
(2013)
Nature
, vol.493
, pp. 338-345
-
-
Johnson, S.C.1
Rabinovitch, P.S.2
Kaeberlein, M.3
-
26
-
-
11144343679
-
Therapeutic potential of target of rapamycin inhibitors
-
DOI 10.1517/14728222.8.6.551
-
Easton, J. B. & Houghton, P. J. Therapeutic potential of target of rapamycin inhibitors. Expert. Opin. Ther. Targets. 8, 551-564 (2004). (Pubitemid 40028366)
-
(2004)
Expert Opinion on Therapeutic Targets
, vol.8
, Issue.6
, pp. 551-564
-
-
Easton, J.B.1
Houghton, P.J.2
-
27
-
-
84894109257
-
Mammalian target of rapamycin signaling in cardiac physiology and disease
-
Sciarretta, S., Volpe, M. & Sadoshima, J. Mammalian target of rapamycin signaling in cardiac physiology and disease. Circ. Res. 114, 549-564 (2014).
-
(2014)
Circ. Res.
, vol.114
, pp. 549-564
-
-
Sciarretta, S.1
Volpe, M.2
Sadoshima, J.3
-
28
-
-
84885085833
-
Knockdown of mTOR by lentivirusmediated RNA interference suppresses atherosclerosis and stabilizes plaques via a decrease of macrophages by autophagy in apolipoprotein Edeficient mice
-
Wang, X. et al. Knockdown of mTOR by lentivirusmediated RNA interference suppresses atherosclerosis and stabilizes plaques via a decrease of macrophages by autophagy in apolipoprotein Edeficient mice. Int. J. Mol. Med. 32, 1215-1221 (2013).
-
(2013)
Int. J. Mol. Med.
, vol.32
, pp. 1215-1221
-
-
Wang, X.1
-
29
-
-
80053443687
-
Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling
-
Lemaitre, V., Dabo, A. J. & D'Armiento, J. Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling. Toxicol. Sci. 123, 542-549 (2011).
-
(2011)
Toxicol. Sci.
, vol.123
, pp. 542-549
-
-
Lemaitre, V.1
Dabo, A.J.2
D'armiento, J.3
-
30
-
-
84880986745
-
The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation
-
Yentrapalli, R. et al. The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation. PloS one 8, e70024 (2013).
-
(2013)
PloS One
, vol.8
-
-
Yentrapalli, R.1
-
31
-
-
72149107100
-
The first-generation drug-eluting stents and coronary endothelial dysfunction
-
Pendyala, L. K. et al. The first-generation drug-eluting stents and coronary endothelial dysfunction. JACC. Cardiovasc. Interv. 2, 1169-1177 (2009).
-
(2009)
JACC. Cardiovasc. Interv.
, vol.2
, pp. 1169-1177
-
-
Pendyala, L.K.1
-
32
-
-
77950890848
-
Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy
-
Zabirnyk, O., Liu,W., Khalil, S., Sharma, A. & Phang, J. M. Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy. Carcinogenesis 31, 446-454 (2010).
-
(2010)
Carcinogenesis
, vol.31
, pp. 446-454
-
-
Zabirnyk, O.1
Liu, W.2
Khalil, S.3
Sharma, A.4
Phang, J.M.5
-
33
-
-
82255186823
-
Toll-like receptor 4 is up-regulated by mTOR activation during THP-1 macrophage foam cells formation
-
Yu,M., Kang, X., Xue, H. & Yin, H. Toll-like receptor 4 is up-regulated by mTOR activation during THP-1 macrophage foam cells formation. Acta. Biochim. Biophys. Sin. 43, 940-947 (2011).
-
(2011)
Acta. Biochim. Biophys. Sin.
, vol.43
, pp. 940-947
-
-
Kang, X.1
Xue, H.2
Yin, H.3
-
34
-
-
84872719653
-
Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis
-
Ding, Z. et al. Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis. Sci. Rep. 3, 1077 (2013).
-
(2013)
Sci. Rep.
, vol.3
, pp. 1077
-
-
Ding, Z.1
-
35
-
-
61949233502
-
Autophagy in atherosclerosis: A cell survival and death phenomenon with therapeutic potential
-
Martinet, W. & De Meyer, G. R. Autophagy in atherosclerosis: a cell survival and death phenomenon with therapeutic potential. Circ. Res. 104, 304-317 (2009).
-
(2009)
Circ. Res.
, vol.104
, pp. 304-317
-
-
Martinet, W.1
De Meyer, G.R.2
-
36
-
-
25144506835
-
Autophagy in cell death: An innocent convict?
-
DOI 10.1172/JCI26390
-
Levine, B. & Yuan, J. Autophagy in cell death: an innocent convict? J. Clin. Invest. 115, 2679-2688 (2005). (Pubitemid 41434392)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2679-2688
-
-
Levine, B.1
Yuan, J.2
-
37
-
-
81755178342
-
Autophagy in atherosclerosis: A potential drug target for plaque stabilization
-
Schrijvers, D. M., DeMeyer, G. R. & Martinet, W. Autophagy in atherosclerosis: a potential drug target for plaque stabilization. Arterioscler. Thromb. Vasc. Biol. 31, 2787-2791 (2011).
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, pp. 2787-2791
-
-
Schrijvers, D.M.1
Demeyer, G.R.2
Martinet, W.3
-
38
-
-
84891719799
-
Evidence for rapamycin toxicity in pancreatic beta-cells and a review of the underlying molecular mechanisms
-
Barlow, A.D., Nicholson, M. L. & Herbert, T. P. Evidence for rapamycin toxicity in pancreatic beta-cells and a review of the underlying molecular mechanisms. Diabetes 62, 2674-2682 (2013).
-
(2013)
Diabetes
, vol.62
, pp. 2674-2682
-
-
Barlow, A.D.1
Nicholson, M.L.2
Herbert, T.P.3
-
39
-
-
85041813459
-
Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research
-
Kilkenny, C., Browne, W. J., Cuthill, I. C., Emerson, M. & Altman, D. G. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS. Biol. 8, e1000412 (2010).
-
(2010)
PLoS. Biol.
, vol.8
-
-
Kilkenny, C.1
Browne, W.J.2
Cuthill, I.C.3
Emerson, M.4
Altman, D.G.5
-
40
-
-
0015822275
-
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
-
Jaffe, E. A., Nachman, R. L., Becker, C. G. & Minick, C. R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52, 2745-2756 (1973).
-
(1973)
J. Clin. Invest.
, vol.52
, pp. 2745-2756
-
-
Jaffe, E.A.1
Nachman, R.L.2
Becker, C.G.3
Minick, C.R.4
|