The role of chloride in the mechanism of O2 activation at the mononuclear nonheme Fe(II) center of the halogenase HctB

Journal of the American Chemical Society

Volumn 136, Issue 26, 2014, Pages 9385-9395

  Pratter, Sarah M ^a   Light, Kenneth M ^b   Solomon, Edward I ^b   Straganz, Grit D ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; CHLORINE COMPOUNDS; DICHROISM; ENZYMES; MOLECULAR DYNAMICS;

CONFORMATIONAL CHANGE; ENZYME-SUBSTRATE COMPLEXES; MOLECULAR DYNAMICS SIMULATIONS; OXIDATIVE TRANSFORMATIONS; SATURATING CONCENTRATION; STOPPED-FLOW KINETICS; TRIGONAL BIPYRAMIDAL; VARIABLE TEMPERATURE;

IRON COMPOUNDS;

2 OXOGLUTARIC ACID; CHLORIDE; ENZYME; HALOGENASE HCTB; NONHEME IRON PROTEIN; OXYGEN; UNCLASSIFIED DRUG; ALPHA-KETOGLUTARIC ACID; BACTERIAL PROTEIN; HEME; IRON; OXIDOREDUCTASE;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; COVALENT BOND; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; FLOW KINETICS; GEOMETRY; MOLECULAR DYNAMICS; OXIDATION; PROTEIN STRUCTURE; TEMPERATURE; CHEMISTRY; ENZYME ACTIVE SITE; KINETICS; METABOLISM; PROTEIN TERTIARY STRUCTURE;

BACTERIAL PROTEINS; CATALYTIC DOMAIN; CHLORIDES; CIRCULAR DICHROISM; ENZYME ACTIVATION; HEME; IRON; KETOGLUTARIC ACIDS; KINETICS; MOLECULAR DYNAMICS SIMULATION; OXIDOREDUCTASES; OXYGEN; PROTEIN STRUCTURE, TERTIARY;

EID: 84903726761     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja503179m     Document Type: Article

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