BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5 recruitment at the cytocortex

BMC Biology

Volumn 12, Issue , 2014, Pages 1-17

  Hiepen, Christian ^a   Benn, Andreas ^a   Denkis, Agnieszka ^a   Lukonin, Ilya ^a   Weise, Christoph ^a   Boergermann, Jan H ^a   Knaus, Petra ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Actin; BMP; BMP receptor; Chemotaxis; LL5beta; Migration; p110alpha; p55gamma; PHLDB2; PIK3R3

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; ANDROSTANE DERIVATIVE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CARRIER PROTEIN; INOSITOL 3,4,5 TRISPHOSPHATE; INOSITOL 3,4,5-TRISPHOSPHATE; INOSITOL PHOSPHATE; LL5BETA PROTEIN, MOUSE; MEMBRANE PROTEIN; PEPTIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PHOSPHOTYROSINE; WORTMANNIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CHEMOTAXIS; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; HEK293 CELL LINE; HUMAN; MESODERM; METABOLISM; MOLECULAR GENETICS; MOUSE; MYOBLAST; PHOSPHORYLATION; PROTEIN BINDING; PSEUDOPODIUM; SIGNAL TRANSDUCTION;

ACTINS; AMINO ACID SEQUENCE; ANDROSTADIENES; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CARRIER PROTEINS; CELL LINE; CHEMOTAXIS; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; HEK293 CELLS; HUMANS; INOSITOL PHOSPHATES; MEMBRANE PROTEINS; MESODERM; MICE; MICROFILAMENT PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MYOBLASTS; PEPTIDES; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN BINDING; PSEUDOPODIA; SIGNAL TRANSDUCTION;

VERTEBRATA;

EID: 84903726327     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-12-43     Document Type: Article

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