-
1
-
-
84873163534
-
Anticancer mechanisms and clinical application of alkylphospholipids
-
van Blitterswijk, W.J.; Verheij, M. Anticancer mechanisms and clinical application of alkylphospholipids. Biochim. Biophys. Acta, 2013, 1831(3), 663-674.
-
(2013)
Biochim. Biophys. Acta
, vol.1831
, Issue.3
, pp. 663-674
-
-
van Blitterswijk, W.J.1
Verheij, M.2
-
2
-
-
61349112191
-
Antitumor alkyl ether lipid edelfosine: Tissue distribution and pharmacokinetic behavior in healthy and tumor-bearing immunosup-pressed mice
-
Estella-Hermoso de Mendoza, A.; Campanero, M.A.; De la Iglesia-Vicente, J.; Gajate, C; Mollinedo, F.; Blanco-Prieto, M.J. Antitumor alkyl ether lipid edelfosine: tissue distribution and pharmacokinetic behavior in healthy and tumor-bearing immunosup-pressed mice. Clin. Cancer Res., 2009, 15(3), 858-864.
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.3
, pp. 858-864
-
-
De Estella-Hermoso Mendoza, A.1
Campanero, M.A.2
De la Iglesia-Vicente, J.3
Gajate, C.4
Mollinedo, F.5
Blanco-Prieto, M.J.6
-
3
-
-
84866850021
-
Lipid nanoparticles for cancer therapy: State of the art and future prospects
-
Lasa-Saracibar, B.; Estella-Hermoso de Mendoza, A.; Guada, M.; Dios-Vieitez, C; Blanco-Prieto, M.J. Lipid nanoparticles for cancer therapy: state of the art and future prospects. Expert Opin. Drug Deliv., 2012, 9(10), 1245-1261.
-
(2012)
Expert Opin. Drug Deliv
, vol.9
, Issue.10
, pp. 1245-1261
-
-
Lasa-Saracibar, B.1
De Estella-Hermoso Mendoza, A.2
Guada, M.3
Dios-Vieitez, C.4
Blanco-Prieto, M.J.5
-
4
-
-
77954237062
-
Lipid raft-targeted therapy in multiple myeloma
-
Mollinedo, F.; De la Iglesia-Vicente, J.; Gajate, C; Estella-Hermoso de Mendoza, A.; Villa-Pulgarin, J.A.; Campanero, M.A.; Blanco-Prieto, M.J. Lipid raft-targeted therapy in multiple myeloma. Oncogene, 2010, 29(26), 3748-3757.
-
(2010)
Oncogene
, vol.29
, Issue.26
, pp. 3748-3757
-
-
Mollinedo, F.1
De la Iglesia-Vicente, J.2
Gajate, C.3
Estella-Hermoso de mendoza, A.4
Villa-Pulgarin, J.A.5
Campanero, M.A.6
Blanco-Prieto, M.J.7
-
5
-
-
37849010813
-
Lipid nanoparticles for alkyl lysophospholipid edelfosine encapsulation: Development and in vitro characterization
-
Estella-Hermoso de Mendoza, A.; Rayo, M.; Mollinedo, F.; Blanco-Prieto, M.J. Lipid nanoparticles for alkyl lysophospholipid edelfosine encapsulation: development and in vitro characterization. Eur. J. Pharm. Biopharm., 2008, 68(2), 207-213.
-
(2008)
Eur. J. Pharm. Biopharm
, vol.68
, Issue.2
, pp. 207-213
-
-
Estella-Hermoso de mendoza, A.1
Rayo, M.2
Mollinedo, F.3
Blanco-Prieto, M.J.4
-
6
-
-
20044371666
-
The Caco-2 cell line as a model of the intestinal barrier: Influence of cell and culture-related factors on Caco-2 cell functional characteristics
-
Sambuy, Y.; De Angelis, I.; Ranaldi, G.; Scarino, M. L.; Stammati, A.; Zucco, F. The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics. Cell Biol. Toxicol, 2005, 21(1), 1-26.
-
(2005)
Cell Biol. Toxicol
, vol.21
, Issue.1
, pp. 1-26
-
-
Sambuy, Y.1
de Angelis, I.2
Ranaldi, G.3
Scarino, M.L.4
Stammati, A.5
Zucco, F.6
-
7
-
-
84879336857
-
Microfold (M) cells: Important immunosurveillance posts in the intestinal epithelium
-
Mabbott, N.A.; Donaldson, D.S.; Ohno, H.; Williams, I.R.; Mahajan, A. Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Mucosal Immunol, 2013, 6(4), 666-677.
-
(2013)
Mucosal Immunol
, vol.6
, Issue.4
, pp. 666-677
-
-
Mabbott, N.A.1
Donaldson, D.S.2
Ohno, H.3
Williams, I.R.4
Mahajan, A.5
-
8
-
-
84875219051
-
Establishment of a triple co-culture in vitro cell models to study intestinal absorption of peptide drugs
-
Antunes, F.; Andrade, F.; Araujo, F.; Ferreira, D.; Sarmento, B. Establishment of a triple co-culture in vitro cell models to study intestinal absorption of peptide drugs. Eur. J. Pharm. Biopharm., 2012, 83(3), 427-435.
-
(2012)
Eur. J. Pharm. Biopharm
, vol.83
, Issue.3
, pp. 427-435
-
-
Antunes, F.1
Andrade, F.2
Araujo, F.3
Ferreira, D.4
Sarmento, B.5
-
9
-
-
33947265152
-
An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells
-
des Rieux, A.; Fievez, V.; Theate, I.; Mast, J.; Preat, V.; Schneider, Y.J. An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells. Eur. J. Pharm. Sci., 2007, 30(5), 380-391.
-
(2007)
Eur. J. Pharm. Sci
, vol.30
, Issue.5
, pp. 380-391
-
-
des Rieux, A.1
Fievez, V.2
Theate, I.3
Mast, J.4
Preat, V.5
Schneider, Y.J.6
-
10
-
-
84872812121
-
Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier
-
Beloqui, A.; Solinis, M.A.; Gascon, A.R.; del Pozo-Rodriguez, A.; des Rieux, A.; Preat, V. Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier. J. Control. Release, 2012, 166(2), 115-123.
-
(2012)
J. Control. Release
, vol.166
, Issue.2
, pp. 115-123
-
-
Beloqui, A.1
Solinis, M.A.2
Gascon, A.R.3
del Pozo-Rodriguez, A.4
des Rieux, A.5
Preat, V.6
-
11
-
-
0038946003
-
Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria
-
Kerneis, S.; Bogdanova, A.; Kraehenbuhl, J.P.; Pringault, E. Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria. Science, 1997, 277(5328), 949.
-
(1997)
Science
, vol.277
, Issue.5328
, pp. 949
-
-
Kerneis, S.1
Bogdanova, A.2
Kraehenbuhl, J.P.3
Pringault, E.4
-
12
-
-
0346728612
-
Cell culture modeling of specialized tissue: Identification of genes expressed specifically by follicle-associated epithelium of Peyer's patch by expression profiling of Caco-2/Raji co-cultures
-
Tynan, W.; Dickerson, J.; Scharf, M.; Cooper, J.; Byrne, D.; Brayden, D.; Higgins, L.; Evans, C; O'Mahony, D.J. Cell culture modeling of specialized tissue: identification of genes expressed specifically by follicle-associated epithelium of Peyer's patch by expression profiling of Caco-2/Raji co-cultures. Int. Immunol, 2004, 16(1), 91-99.
-
(2004)
Int. Immunol
, vol.16
, Issue.1
, pp. 91-99
-
-
Tynan, W.1
Dickerson, J.2
Scharf, M.3
Cooper, J.4
Byrne, D.5
Brayden, D.6
Higgins, L.7
Evans, C.8
O'Mahony, D.J.9
-
13
-
-
85039607466
-
-
Spain. Patent P201130433, October, 03
-
Ander Estella-Hermoso de Mendoza, M.J.B.-P., Miguel Angel Campanero, Faustino Mollinedo, Janny Villa-Pulgarín, Rubén Va-rela. Development and use of lipidic nanoparticles loaded with edelfosine and ether phospholipids in antitumoral and antiparasitic therapy. Spain. Patent P201130433, October, 03, 2011.
-
(2011)
Development and Use of Lipidic Nanoparticles Loaded With Edelfosine and Ether Phospholipids In Antitumoral and Antiparasitic Therapy
-
-
De Ander Estella-Hermoso Mendoza, M.J.B.-P.1
Campanero Miguel, A.2
Mollinedo, F.3
Villa-Pulgarín, J.4
Va-Rela, R.5
-
14
-
-
72049114741
-
Comparative study of A HPLC-MS assay versus an UHPLC-MS/MS for anti-tumoral alkyl lysophospholipid edelfosine determination in both biological samples and in lipid nanoparticulate systems
-
Estella-Hermoso de Mendoza, A.; Campanero, M.A.; Mollinedo, F.; Blanco-Prieto, M.J. Comparative study of A HPLC-MS assay versus an UHPLC-MS/MS for anti-tumoral alkyl lysophospholipid edelfosine determination in both biological samples and in lipid nanoparticulate systems. J. Chromatogr. B Analyt. Technol. Bio-med. Life Sci., 2009, 877(31), 4035-4041.
-
(2009)
J. Chromatogr. B Analyt. Technol. Bio-med. Life Sci
, vol.877
, Issue.31
, pp. 4035-4041
-
-
De Estella-Hermoso Mendoza, A.1
Campanero, M.A.2
Mollinedo, F.3
Blanco-Prieto, M.J.4
-
15
-
-
84903722586
-
-
Millicell® ERS-2 User Guide, Accesed Sept 11, 2013)
-
Millicell® ERS-2 User Guide. http://www.millipore.com/user_guides.nsf/a73664f9f981af8c852569b9005b4eee/a5708d8207d7acc f85257609005c7c5f/$FILE/00108103.pdf (Accesed Sept 11, 2013).
-
-
-
-
16
-
-
80051546370
-
The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine
-
Pusch, J.; Votteler, M.; Gohler, S.; Engl, J.; Hampel, M.; Walles, H.; Schenke-Layland, K. The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine. Biomaterials, 2011, 32(30), 7469-7478.
-
(2011)
Biomaterials
, vol.32
, Issue.30
, pp. 7469-7478
-
-
Pusch, J.1
Votteler, M.2
Gohler, S.3
Engl, J.4
Hampel, M.5
Walles, H.6
Schenke-Layland, K.7
-
17
-
-
82755182780
-
In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma
-
Estella-Hermoso deMendoza, A.; Preat, V.; Mollinedo, F.; Blanco-Prieto, M.J. In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma. J. Control. Release, 2011, 156(3), 421-426.
-
(2011)
J. Control. Release
, vol.156
, Issue.3
, pp. 421-426
-
-
Estella-Hermoso demendoza, A.1
Preat, V.2
Mollinedo, F.3
Blanco-Prieto, M.J.4
-
18
-
-
84878219061
-
Edelfosine lipid nanosystems overcome drug resistance in leukemic cell lines
-
Lasa-Saracibar, B.; Estella-Hermoso de Mendoza, A.; Mollinedo, F.; Odero, M.D.; Blanco-Prieto, M.J. Edelfosine lipid nanosystems overcome drug resistance in leukemic cell lines. Cancer Lett, 2013, 334(2), 302-310.
-
(2013)
Cancer Lett
, vol.334
, Issue.2
, pp. 302-310
-
-
Lasa-Saracibar, B.1
De Estella-Hermoso Mendoza, A.2
Mollinedo, F.3
Odero, M.D.4
Blanco-Prieto, M.J.5
-
19
-
-
0034731393
-
Expression of specific markers and particle transport in a new human intestinal M-cell model
-
Gullberg, E.; Leonard, M.; Karlsson, J.; Hopkins, A.M.; Brayden, D.; Baird, A.W.; Artursson, P. Expression of specific markers and particle transport in a new human intestinal M-cell model. Bio-chem. Biophys. Res. Commun., 2000, 279(3), 808-813.
-
(2000)
Bio-chem. Biophys. Res. Commun
, vol.279
, Issue.3
, pp. 808-813
-
-
Gullberg, E.1
Leonard, M.2
Karlsson, J.3
Hopkins, A.M.4
Brayden, D.5
Baird, A.W.6
Artursson, P.7
-
20
-
-
0023030826
-
Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
-
Stevenson, B.R.; Siliciano, J.D.; Mooseker, M.S.; Goodenough, D.A. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell. Biol, 1986, 103(3), 755-766.
-
(1986)
J. Cell. Biol
, vol.103
, Issue.3
, pp. 755-766
-
-
Stevenson, B.R.1
Siliciano, J.D.2
Mooseker, M.S.3
Goodenough, D.A.4
-
21
-
-
0030023173
-
Cytosolic distribution of villin in M cells from mouse Peyer's patches correlates with the absence of a brush border
-
Kerneis, S.; Bogdanova, A.; Colucci-Guyon, E.; Kraehenbuhl, J.P.; Pringault, E. Cytosolic distribution of villin in M cells from mouse Peyer's patches correlates with the absence of a brush border. Gastroenterology, 1996, 110(2), 515-521.
-
(1996)
Gastroenterology
, vol.110
, Issue.2
, pp. 515-521
-
-
Kerneis, S.1
Bogdanova, A.2
Colucci-Guyon, E.3
Kraehenbuhl, J.P.4
Pringault, E.5
-
22
-
-
0025153163
-
New fluorescent dyes for lymphocyte migration studies. Analysis by flow cytometry and fluorescence microscopy
-
Weston, S.A.; Parish, C.R. New fluorescent dyes for lymphocyte migration studies. Analysis by flow cytometry and fluorescence microscopy. J. Immunol. Methods, 1990, 133(1), 87-97.
-
(1990)
J. Immunol. Methods
, vol.133
, Issue.1
, pp. 87-97
-
-
Weston, S.A.1
Parish, C.R.2
-
23
-
-
84857973669
-
Overcoming drug efflux-based multidrug resistance in cancer with nanotechnology
-
Xue, X.; Liang, X.J. Overcoming drug efflux-based multidrug resistance in cancer with nanotechnology. Chin. J. Cancer, 2012, 31(2), 100-109.
-
(2012)
Chin. J. Cancer
, vol.31
, Issue.2
, pp. 100-109
-
-
Xue, X.1
Liang, X.J.2
-
24
-
-
0041402719
-
Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells
-
Troutman, M.D.; Thakker, D.R. Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells. Pharm. Res., 2003, 20(8), 1192-1199.
-
(2003)
Pharm. Res
, vol.20
, Issue.8
, pp. 1192-1199
-
-
Troutman, M.D.1
Thakker, D.R.2
-
25
-
-
70350617685
-
Lipid nanocarriers improve paclitaxel transport throughout human intestinal epithelial cells by using vesicle-mediated transcytosis
-
Roger, E.; Lagarce, F.; Garcion, E.; Benoit, J.P. Lipid nanocarriers improve paclitaxel transport throughout human intestinal epithelial cells by using vesicle-mediated transcytosis. J. Control. Release, 2009, 140(2), 174-181.
-
(2009)
J. Control. Release
, vol.140
, Issue.2
, pp. 174-181
-
-
Roger, E.1
Lagarce, F.2
Garcion, E.3
Benoit, J.P.4
-
26
-
-
0036783411
-
Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells
-
Gajate, C; Mollinedo, F. Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells. Curr. Drug Metab., 2002, 3(5), 491-525.
-
(2002)
Curr. Drug Metab
, vol.3
, Issue.5
, pp. 491-525
-
-
Gajate, C.1
Mollinedo, F.2
-
27
-
-
0023471998
-
The degradation of platelet-activating factor and related lipids: Susceptibility to phospholipases C and D
-
Wilcox, R.W.; Wykle, R.L.; Schmitt, J.D.; Daniel, L.W. The degradation of platelet-activating factor and related lipids: susceptibility to phospholipases C and D. Lipids, 1987, 22(11), 800-807.
-
(1987)
Lipids
, vol.22
, Issue.11
, pp. 800-807
-
-
Wilcox, R.W.1
Wykle, R.L.2
Schmitt, J.D.3
Daniel, L.W.4
-
28
-
-
0028815154
-
Fate of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET18-OME) in malignant cells, normal cells, and isolated and perfused rat liver. Drug Metab
-
Magistrelli, A.; Villa, P.; Benfenati, E.; Modest, E.J.; Salmona, M.; Tacconi, M.T. Fate of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET18-OME) in malignant cells, normal cells, and isolated and perfused rat liver. Drug Metab. Dispos., 1995, 23(1), 113-118.
-
(1995)
Dispos
, vol.23
, Issue.1
, pp. 113-118
-
-
Magistrelli, A.1
Villa, P.2
Benfenati, E.3
Modest, E.J.4
Salmona, M.5
Tacconi, M.T.6
-
29
-
-
77951257204
-
Interaction of biodegradable nanoparticles with intestinal cells: The effect of surface hydrophilic-ity
-
Gaumet, M.; Gurny, R.; Delie, F. Interaction of biodegradable nanoparticles with intestinal cells: the effect of surface hydrophilic-ity. Int. J. Pharm., 2009, 390(1), 45-52.
-
(2009)
Int. J. Pharm
, vol.390
, Issue.1
, pp. 45-52
-
-
Gaumet, M.1
Gurny, R.2
Delie, F.3
-
30
-
-
0034893953
-
Kinetics of P-glycoprotein-mediated efflux of paclitaxel
-
Jang, S.H.; Wientjes, M.G.; Au, J.L. Kinetics of P-glycoprotein-mediated efflux of paclitaxel. J. Pharmacol. Exp. Ther., 2001, 298(3), 1236-1242.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.298
, Issue.3
, pp. 1236-1242
-
-
Jang, S.H.1
Wientjes, M.G.2
Au, J.L.3
-
31
-
-
0345017084
-
Lipid rafts in epithelial brush borders: Atypical membrane microdomains with specialized functions
-
Danielsen, E.M.; Hansen, G.H. Lipid rafts in epithelial brush borders: atypical membrane microdomains with specialized functions. Biochim. Biophys. Acta, 2003, 1617(1-2), 1-9.
-
(2003)
Biochim. Biophys. Acta
, vol.1617
, Issue.1-2
, pp. 1-9
-
-
Danielsen, E.M.1
Hansen, G.H.2
-
32
-
-
77954506437
-
Domains of increased thickness in microvillar membranes of the small intestinal enterocyte
-
Kunding, A.H.; Christensen, S.M.; Danielsen, E.M.; Hansen, G.H. Domains of increased thickness in microvillar membranes of the small intestinal enterocyte. Mol.Membr. Biol, 2010, 27(4-6), 170-177.
-
(2010)
Mol.Membr. Biol
, vol.27
, Issue.4-6
, pp. 170-177
-
-
Kunding, A.H.1
Christensen, S.M.2
Danielsen, E.M.3
Hansen, G.H.4
-
33
-
-
53049091268
-
Edel-fosine is incorporated into rafts and alters their organization
-
Ausili, A.; Torrecillas, A.; Aranda, F.J.; Mollinedo, F.; Gajate, C; Corbalan-Garcia, S.; de Godos, A.; Gomez-Fernandez, J.C. Edel-fosine is incorporated into rafts and alters their organization. J. Phys. Chem. B, 2008, 112(37), 11643-11654.
-
(2008)
J. Phys. Chem. B
, vol.112
, Issue.37
, pp. 11643-11654
-
-
Ausili, A.1
Torrecillas, A.2
Aranda, F.J.3
Mollinedo, F.4
Gajate, C.5
Corbalan-Garcia, S.6
de Godos, A.7
Gomez-Fernandez, J.C.8
-
34
-
-
84898488352
-
Differentiation of human induced pluripotent stem cells into functional enterocyte-like cells using a simple method
-
Iwao, T.; Toyota, M.; Miyagawa, Y.; Okita, H.; Kiyokawa, N.; Akutsu, H.; Umezawa, A.; Nagata, K.; Matsunaga, T. Differentiation of human induced pluripotent stem cells into functional enterocyte-like cells using a simple method. Drug Metab. Pharmacok., 2013 (http://dx.doi.org/10.2133/dmpk.DMPK-13-RG-005).
-
(2013)
Drug Metab. Pharmacok
-
-
Iwao, T.1
Toyota, M.2
Miyagawa, Y.3
Okita, H.4
Kiyokawa, N.5
Akutsu, H.6
Umezawa, A.7
Nagata, K.8
Matsunaga, T.9
-
35
-
-
80955137949
-
Generating human intestinal tissue from pluripotent stem cells in vitro
-
McCracken K.W.; Howell, J.C; Wells, J.M.; Spence, J.R. Generating human intestinal tissue from pluripotent stem cells in vitro. Nat. Protoc, 2011, 6(12), 1920-1928.
-
(2011)
Nat. Protoc
, vol.6
, Issue.12
, pp. 1920-1928
-
-
McCracken, K.W.1
Howell, J.C.2
Wells, J.M.3
Spence, J.R.4
|