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Volumn 31, Issue 2, 2012, Pages 100-109

Overcoming drug efflux-based multidrug resistance in cancer with nanotechnology

Author keywords

Cancer nanotechnology; Drug efflux transporter; Multidrug resistance

Indexed keywords

DOXORUBICIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; SMALL INTERFERING RNA;

EID: 84857973669     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.011.10326     Document Type: Review
Times cited : (137)

References (71)
  • 1
    • 0141782300 scopus 로고    scopus 로고
    • The World Cancer Report-the major findings
    • The World Cancer Report-the major findings. Cent Eur J Public Health, 2003,11:177-179.
    • (2003) Cent Eur J Public Health , vol.11 , pp. 177-179
  • 2
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-gl ycoprotein) gene from multi drug-re sistant human cells
    • Chen CJ, Chin JE, Ueda K, et al. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-gl ycoprotein) gene from multi drug-re sistant human cells. Cell, 1986,47:381-389.
    • (1986) Cell , vol.47 , pp. 381-389
    • Chen, C.J.1    Chin, J.E.2    Ueda, K.3
  • 3
    • 0023644587 scopus 로고
    • Assembly of the mitochondrial membrane system. MRP1 and MRP2, two yeastnuclear genes coding for mitochondrial ribosomal proteins
    • Myers AM, Crivellone MD, Tzagoloff A. Assembly of the mitochondrial membrane system. MRP1 and MRP2, two yeastnuclear genes coding for mitochondrial ribosomal proteins. J Biol Chem, 1987,262:3388-3397.
    • (1987) J Biol Chem , vol.262 , pp. 3388-3397
    • Myers, A.M.1    Crivellone, M.D.2    Tzagoloff, A.3
  • 4
    • 0033568540 scopus 로고    scopus 로고
    • Over expression of the BCRP/MXR/ABCP gene in a topotecan- selected ovarian tumor cell line
    • Maliepaard M, van Gastelen MA, de Jong LA, et al. Over expression of the BCRP/MXR/ABCP gene in a topotecan- selected ovarian tumor cell line. Cancer Res, 1999,59:4559-4563.
    • (1999) Cancer Res , vol.59 , pp. 4559-4563
    • Maliepaard, M.1    van Gastelen, M.A.2    de Jong, L.A.3
  • 5
    • 1442286330 scopus 로고    scopus 로고
    • The role of Bcl-2 family members in tumorigenesis
    • Kirkin V, Joos S, Zornig M. The role of Bcl-2 family members in tumorigenesis. Biochim Biophys Acta, 2004,1644:229-249.
    • (2004) Biochim Biophys Acta , vol.1644 , pp. 229-249
    • Kirkin, V.1    Joos, S.2    Zornig, M.3
  • 7
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human MDR1 gene by Ras and p53
    • Chin KV, Ueda K, Pastan I, et al. Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. Science, 1992,255:459-462.
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.V.1    Ueda, K.2    Pastan, I.3
  • 8
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • Leonard GD, Fojo T, Bates SE. The role of ABC transporters in clinical practice. Oncologist, 2003,8:411-424.
    • (2003) Oncologist , vol.8 , pp. 411-424
    • Leonard, G.D.1    Fojo, T.2    Bates, S.E.3
  • 9
    • 43149118341 scopus 로고    scopus 로고
    • The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-TO X)
    • Szakacs G, Varadi A, Ozvegy-Laczka C, et al. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-TO X). Drug Discov Today, 2008,13:379-393.
    • (2008) Drug Discov Today , vol.13 , pp. 379-393
    • Szakacs, G.1    Varadi, A.2    Ozvegy-Laczka, C.3
  • 10
    • 2542491777 scopus 로고    scopus 로고
    • The role of ABC transporters in drug resistance, metabolism and toxicity
    • Glavinas H, Krajcsi P, Cserepes J, et al. The role of ABC transporters in drug resistance, metabolism and toxicity. Curr Drug Deliv, 2004,1:27-47
    • (2004) Curr Drug Deliv , vol.1 , pp. 27-47
    • Glavinas, H.1    Krajcsi, P.2    Cserepes, J.3
  • 11
    • 34247403759 scopus 로고    scopus 로고
    • Use of arrays to investigate the contribution of ATP- binding cassette transporters to drug resistance in cancer chemotherapy and prediction of chemosensitivity
    • Zhang JT. Use of arrays to investigate the contribution of ATP- binding cassette transporters to drug resistance in cancer chemotherapy and prediction of chemosensitivity. Cell Res, 2007,17: 311-323.
    • (2007) Cell Res , vol.17 , pp. 311-323
    • Zhang, J.T.1
  • 12
    • 0036364467 scopus 로고    scopus 로고
    • Multi drug resistance in cancer: Role of ATP-de pendent transporters
    • Gottesman MM, Fojo T, Bates SE. Multi drug resistance in cancer: role of ATP-de pendent transporters. Nat Rev Cancer, 2002,2: 48-58.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 13
    • 77958577303 scopus 로고    scopus 로고
    • Down-re gulation of P-gl ycoprotein is associated with resistance to cisplatin and VP-16 in human lung cancer cell lines
    • Wang Q, Wang JR, Wang HL, et al. Down-re gulation of P-gl ycoprotein is associated with resistance to cisplatin and VP-16 in human lung cancer cell lines. Anticancer Res, 2010,30: 3593-3598.
    • (2010) Anticancer Res , vol.30 , pp. 3593-3598
    • Wang, Q.1    Wang, J.R.2    Wang, H.L.3
  • 14
    • 0034991901 scopus 로고    scopus 로고
    • Increase in doxorubicin cytotoxicity by inhibition of P-gl ycoprotein activity with lomerizine
    • Shiraki N, Hamada A, Ohmura T, et al. Increase in doxorubicin cytotoxicity by inhibition of P-gl ycoprotein activity with lomerizine. Biol Pharm Bull, 2001,24: 555-557.
    • (2001) Biol Pharm Bull , vol.24 , pp. 555-557
    • Shiraki, N.1    Hamada, A.2    Ohmura, T.3
  • 15
    • 0032889057 scopus 로고    scopus 로고
    • Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-gl ycoprotein
    • van Asperen J, van Tellingen O, Tijssen F, et al. Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-gl ycoprotein. Br J Cancer, 1999,79: 108-113.
    • (1999) Br J Cancer , vol.79 , pp. 108-113
    • van Asperen, J.1    van Tellingen, O.2    Tijssen, F.3
  • 16
    • 58849112270 scopus 로고    scopus 로고
    • Inhibition of P-gl ycoprotein-m ediated paclitaxel resistance by reversibly linked quinine homo dimers
    • Pires MM, Emmert D, Hrycyna CA, et al. Inhibition of P-gl ycoprotein-m ediated paclitaxel resistance by reversibly linked quinine homo dimers. Mol Pharmacol, 2009,75:92-100.
    • (2009) Mol Pharmacol , vol.75 , pp. 92-100
    • Pires, M.M.1    Emmert, D.2    Hrycyna, C.A.3
  • 17
    • 0036747416 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein- mediated paclitaxel resistance by new synthetic isoprenoids in human bladder cancer cell line
    • Enokida H, Gotanda T, Oku S, et al. Reversal of P-glycoprotein- mediated paclitaxel resistance by new synthetic isoprenoids in human bladder cancer cell line. Jpn J Cancer Res, 2002,93: 1037-1046.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 1037-1046
    • Enokida, H.1    Gotanda, T.2    Oku, S.3
  • 18
    • 0015963429 scopus 로고
    • Reduced permeability in CHO cells as a mechanism of resistance to colchicine
    • Ling V, Thompson LH. Reduced permeability in CHO cells as a mechanism of resistance to colchicine. J Cell Physiol, 1974,83: 103-116.
    • (1974) J Cell Physiol , vol.83 , pp. 103-116
    • Ling, V.1    Thompson, L.H.2
  • 19
    • 0016223101 scopus 로고
    • Increased drug permeability in Chinese hamster ovary cells in the presence of cyanide
    • See YP, Carlsen SA, Till JE, et al. Increased drug permeability in Chinese hamster ovary cells in the presence of cyanide. Biochim Biophys Acta, 1974,373:242-252.
    • (1974) Biochim Biophys Acta , vol.373 , pp. 242-252
    • See, Y.P.1    Carlsen, S.A.2    Till, J.E.3
  • 20
    • 33846630794 scopus 로고    scopus 로고
    • Nano: The new nemesis of cancer
    • Hede S, Huilgol N. Nano: the new nemesis of cancer. J Cancer Res Ther, 2006,2:186-195.
    • (2006) J Cancer Res Ther , vol.2 , pp. 186-195
    • Hede, S.1    Huilgol, N.2
  • 21
    • 14644396096 scopus 로고    scopus 로고
    • Nano medicine: Current status and future prospects
    • Moghimi SM, Hunter AC, Murray JC. Nano medicine: current status and future prospects. FASEB J, 2005,19:311-330.
    • (2005) FASEB J , vol.19 , pp. 311-330
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 22
    • 70449706006 scopus 로고    scopus 로고
    • Targeting oncogenic signaling pathways by exploiting nanotechnology
    • Basu S, Chaudhuri P, Sengupta S. Targeting oncogenic signaling pathways by exploiting nanotechnology. Cell Cycle, 2009,8:3480-3487.
    • (2009) Cell Cycle , vol.8 , pp. 3480-3487
    • Basu, S.1    Chaudhuri, P.2    Sengupta, S.3
  • 23
    • 35348882024 scopus 로고    scopus 로고
    • Nanotechnology applications in cancer
    • Nie S, Xing Y, Kim GJ, et al. Nanotechnology applications in cancer. Annu Rev Biomed Eng, 2007,9:257-288.
    • (2007) Annu Rev Biomed Eng , vol.9 , pp. 257-288
    • Nie, S.1    Xing, Y.2    Kim, G.J.3
  • 24
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov, 2003,2:347-360.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 347-360
    • Duncan, R.1
  • 25
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the anti tumor agent smancs
    • Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the anti tumor agent smancs. Cancer Res, 1986,46:6387-6392.
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 26
    • 0033302303 scopus 로고    scopus 로고
    • Transport of molecules, particles, and cells in solid tumors
    • Jain RK. Transport of molecules, particles, and cells in solid tumors. Annu Rev Biomed Eng, 1999,1:241-263.
    • (1999) Annu Rev Biomed Eng , vol.1 , pp. 241-263
    • Jain, R.K.1
  • 27
    • 35948988152 scopus 로고    scopus 로고
    • Injectable nano carriers for biodetoxification
    • Leroux JC. Injectable nano carriers for biodetoxification. Nat Nanotechnol, 2007,2:679-684.
    • (2007) Nat Nanotechnol , vol.2 , pp. 679-684
    • Leroux, J.C.1
  • 28
    • 37649010361 scopus 로고    scopus 로고
    • Nano particles for drug delivery in cancer treatment
    • Haley B, Frenkel E. Nano particles for drug delivery in cancer treatment. Urol Oncol, 2008,26:57-64.
    • (2008) Urol Oncol , vol.26 , pp. 57-64
    • Haley, B.1    Frenkel, E.2
  • 29
    • 68949103744 scopus 로고    scopus 로고
    • Drug nanocarriers and functional nano particles: Applications in cancer therapy
    • Thierry B. Drug nanocarriers and functional nano particles: applications in cancer therapy. Curr Drug Deliv, 2009,6:391-403.
    • (2009) Curr Drug Deliv , vol.6 , pp. 391-403
    • Thierry, B.1
  • 30
    • 77953235193 scopus 로고    scopus 로고
    • Nano particle technologies for cancer therapy
    • Alexis F, Pridgen EM, Langer R, et al. Nano particle technologies for cancer therapy. Handb Exp Pharmacol, 2010,197:55-86.
    • (2010) Handb Exp Pharmacol , vol.197 , pp. 55-86
    • Alexis, F.1    Pridgen, E.M.2    Langer, R.3
  • 31
    • 33847341135 scopus 로고    scopus 로고
    • Lipid formulation strategies foren hancing intestinal transport and absorption of P-gl ycoprotein (P-gp) substrate drugs: In vitro/in vivo case studies
    • Constantinides PP, Wasan KM. Lipid formulation strategies foren hancing intestinal transport and absorption of P-gl ycoprotein (P-gp) substrate drugs: in vitro/in vivo case studies. J Pharm Sci, 2007,96:235-248.
    • (2007) J Pharm Sci , vol.96 , pp. 235-248
    • Constantinides, P.P.1    Wasan, K.M.2
  • 33
    • 0032714228 scopus 로고    scopus 로고
    • Inhibition of P-g lycoprotein by D-al pha-to copheryl polyethylene glycol 1000 succinate (TPGS)
    • Dintaman JM, Silverman JA. Inhibition of P-g lycoprotein by D-al pha-to copheryl polyethylene glycol 1000 succinate (TPGS). Pharm Res, 1999,16:1550-1556.
    • (1999) Pharm Res , vol.16 , pp. 1550-1556
    • Dintaman, J.M.1    Silverman, J.A.2
  • 34
    • 0034757615 scopus 로고    scopus 로고
    • Mechanism of pluro nic effect on P-glycoprotein efflux system in blood-br ain barrier: Contributions of energy depletion and membrane fluidization
    • Batrakova EV, Li S, Vinogradov SV, et al. Mechanism of pluro nic effect on P-glycoprotein efflux system in blood-br ain barrier: contributions of energy depletion and membrane fluidization. J Pharmacol Exp Ther, 2001,299:483-493.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 483-493
    • Batrakova, E.V.1    Li, S.2    Vinogradov, S.V.3
  • 35
    • 17744382615 scopus 로고    scopus 로고
    • Effect of pluronic P85 on ATPase activity of drug efflux transporters
    • Batrakova EV, Li S, Li Y, et al. Effect of pluronic P85 on ATPase activity of drug efflux transporters. Pharm Res, 2004, 21:2226-2233.
    • (2004) Pharm Res , vol.21 , pp. 2226-2233
    • Batrakova, E.V.1    Li, S.2    Li, Y.3
  • 36
    • 0027524642 scopus 로고
    • In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative
    • Hyafil F, Vergely C, Du Vignaud P, et al. In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative. Cancer Res, 1993,53:4595-4602.
    • (1993) Cancer Res , vol.53 , pp. 4595-4602
    • Hyafil, F.1    Vergely, C.2    du Vignaud, P.3
  • 37
    • 0030041652 scopus 로고    scopus 로고
    • Flow cytometricassay of modulation of P-gl ycoprotein function in whole blood by the multidrug resistance inhibitor GG918
    • Witherspoon SM, Emerson DL, Kerr BM, et al. Flow cytometricassay of modulation of P-gl ycoprotein function in whole blood by the multidrug resistance inhibitor GG918. Clin Cancer Res, 1996,2:7-12.
    • (1996) Clin Cancer Res , vol.2 , pp. 7-12
    • Witherspoon, S.M.1    Emerson, D.L.2    Kerr, B.M.3
  • 38
    • 77957969261 scopus 로고    scopus 로고
    • Targeting mirnas involved in cancer stem cell and EMT regulation: An emerging concept in overcoming drug resistance
    • Wang Z, Li Y, Ahmad A, et al. Targeting mirnas involved in cancer stem cell and EMT regulation: an emerging concept in overcoming drug resistance. Drug Resist Updat, 2010,13:109-118.
    • (2010) Drug Resist Updat , vol.13 , pp. 109-118
    • Wang, Z.1    Li, Y.2    Ahmad, A.3
  • 39
    • 58249112846 scopus 로고    scopus 로고
    • Polymeric nanoparticles for siRNA delivery and gene silencing
    • Patil Y, Panyam J. Polymeric nanoparticles for siRNA delivery and gene silencing. Int J Pharm, 2009,367:195-203.
    • (2009) Int J Pharm , vol.367 , pp. 195-203
    • Patil, Y.1    Panyam, J.2
  • 40
    • 66649118310 scopus 로고    scopus 로고
    • Therapeutic targeting of ATP7B in ovarian carcinoma
    • Mangala LS, Zuzel V, Schmandt R, et al. Therapeutic targeting of ATP7B in ovarian carcinoma. Clin Cancer Res, 2009,15: 3770-3780.
    • (2009) Clin Cancer Res , vol.15 , pp. 3770-3780
    • Mangala, L.S.1    Zuzel, V.2    Schmandt, R.3
  • 41
    • 78650134637 scopus 로고    scopus 로고
    • Engineered design of meso porous silica nanoparticles to deliver doxorubicin and P-glycoprotein si RNA to overcome drug resistance in a cancer cell line
    • Meng H, Liong M, Xia T, et al. Engineered design of meso porous silica nanoparticles to deliver doxorubicin and P-glycoprotein si RNA to overcome drug resistance in a cancer cell line. ACS Nano, 2010,4:4539-4550.
    • (2010) ACS Nano , vol.4 , pp. 4539-4550
    • Meng, H.1    Liong, M.2    Xia, T.3
  • 42
    • 77957279700 scopus 로고    scopus 로고
    • Sequential treatment of drug-re sistant tumors with RGD-m odified liposomes containing si RNA or doxorubicin
    • Jiang J, Yang SJ, Wang JC, et al. Sequential treatment of drug-re sistant tumors with RGD-m odified liposomes containing si RNA or doxorubicin. Eur J Pharm Biopharm, 2010,76:170-178.
    • (2010) Eur J Pharm Biopharm , vol.76 , pp. 170-178
    • Jiang, J.1    Yang, S.J.2    Wang, J.C.3
  • 43
    • 67650479404 scopus 로고    scopus 로고
    • Sequential treatment of drug-re sistant tumors with targeted minicells containing siRNA or a cytotoxic drug
    • MacDiarmid JA, Amaro-Mugridge NB, Madrid-Weiss J, et al. Sequential treatment of drug-re sistant tumors with targeted minicells containing siRNA or a cytotoxic drug. Nat Biotechnol, 2009,27:643-651.
    • (2009) Nat Biotechnol , vol.27 , pp. 643-651
    • Macdiarmid, J.A.1    Amaro-Mugridge, N.B.2    Madrid-Weiss, J.3
  • 44
    • 77954041825 scopus 로고    scopus 로고
    • Jet-in jection of short hairpin RNA- encoding vectors into tumor cells
    • Walther W, Stein U, Lage H. Jet-in jection of short hairpin RNA- encoding vectors into tumor cells. Methods Mol Biol, 2010,629: 123-139.
    • (2010) Methods Mol Biol , vol.629 , pp. 123-139
    • Walther, W.1    Stein, U.2    Lage, H.3
  • 45
    • 80054713553 scopus 로고    scopus 로고
    • Dendrimer phthalocyanine-encapsulated polymeric micelle-m ediated photochemicalinternalization extends the efficacy of photodynamic therapy and overcomes drug-re sistance in vivo
    • Epub ahead of print
    • Lu HL, Syu WJ, Nishiyama N, et al. Dendrimer phthalocyanine-encapsulated polymeric micelle-m ediated photochemicalinternalization extends the efficacy of photodynamic therapy and overcomes drug-re sistance in vivo. J Control Release, 2011,12, Epub ahead of print.
    • (2011) J Control Release , vol.12
    • Lu, H.L.1    Syu, W.J.2    Nishiyama, N.3
  • 46
    • 67349243616 scopus 로고    scopus 로고
    • Nano particle-m ediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance
    • Patil Y, Sadhukha T, Ma L, et al. Nano particle-m ediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance. J Control Release, 2009,136: 21-29.
    • (2009) J Control Release , vol.136 , pp. 21-29
    • Patil, Y.1    Sadhukha, T.2    Ma, L.3
  • 47
    • 70350707597 scopus 로고    scopus 로고
    • The use of nano particle-m ediated targeted gene silencing and drug delivery to overcome tumor drug resistance
    • Patil YB, Swaminathan SK, Sadhukha T, et al. The use of nano particle-m ediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials, 2010,31:358-365.
    • (2010) Biomaterials , vol.31 , pp. 358-365
    • Patil, Y.B.1    Swaminathan, S.K.2    Sadhukha, T.3
  • 48
    • 79953682278 scopus 로고    scopus 로고
    • Synergy of nab- paclitaxel and bevacizumab in eradicating large orthotopic breast tumors and preexisting metastases
    • Volk LD, Flister MJ, Chihade D, et al. Synergy of nab- paclitaxel and bevacizumab in eradicating large orthotopic breast tumors and preexisting metastases. Neoplasia, 2011,13: 327-338.
    • (2011) Neoplasia , vol.13 , pp. 327-338
    • Volk, L.D.1    Flister, M.J.2    Chihade, D.3
  • 49
    • 59649091887 scopus 로고    scopus 로고
    • Nanoparticle-m ediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance in vitro
    • Khdair A, Handa H, Mao G, et al. Nanoparticle-m ediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance in vitro. Eur J Pharm Biopharm, 2009,71:214-222.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 214-222
    • Khdair, A.1    Handa, H.2    Mao, G.3
  • 50
    • 72149087697 scopus 로고    scopus 로고
    • Nanoparticle-m ediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance
    • Khdair A, Chen D, Patil Y, et al. Nanoparticle-m ediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance. J Control Release, 141:137-144.
    • J Control Release , vol.141 , pp. 137-144
    • Khdair, A.1    Chen, D.2    Patil, Y.3
  • 51
    • 33645650780 scopus 로고    scopus 로고
    • Activation of toll-lik e receptor 2 on microglia promotes cell uptake of alzheimer disease- associated amyloid beta peptide
    • Chen K, Iribarren P, Hu J, et al. Activation of toll-lik e receptor 2 on microglia promotes cell uptake of alzheimer disease- associated amyloid beta peptide. J Biol Chem, 2006,281: 3651-3659.
    • (2006) J Biol Chem , vol.281 , pp. 3651-3659
    • Chen, K.1    Iribarren, P.2    Hu, J.3
  • 52
    • 78049498597 scopus 로고    scopus 로고
    • Development of PLGA nano particles simultaneously loaded with vincristine and verapamil for treatment of hepato cellular carcinoma
    • Song XR, Zheng Y, He G, et al. Development of PLGA nano particles simultaneously loaded with vincristine and verapamil for treatment of hepato cellular carcinoma. J Pharm Sci, 2010,99:4874-4879.
    • (2010) J Pharm Sci , vol.99 , pp. 4874-4879
    • Song, X.R.1    Zheng, Y.2    He, G.3
  • 53
    • 77954599597 scopus 로고    scopus 로고
    • Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer
    • Chen Y, Bathula SR, Li J, et al. Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer. J Biol Chem, 2010,285:22639-22650.
    • (2010) J Biol Chem , vol.285 , pp. 22639-22650
    • Chen, Y.1    Bathula, S.R.2    Li, J.3
  • 54
    • 77950657794 scopus 로고    scopus 로고
    • Augmentation of therapeutic efficacy in drug-re sistant tumor models using ceramide coadministration in temporal-co ntrolled polymer-bl end nanoparticle delivery systems
    • van Vlerken LE, Duan Z, Little SR, et al. Augmentation of therapeutic efficacy in drug-re sistant tumor models using ceramide coadministration in temporal-co ntrolled polymer-bl end nanoparticle delivery systems. AAPS J, 2010,12:171-180.
    • (2010) AAPS J , vol.12 , pp. 171-180
    • van Vlerken, L.E.1    Duan, Z.2    Little, S.R.3
  • 55
    • 77950788603 scopus 로고    scopus 로고
    • Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bo und-ra pamycin and perifosine induces antitumor activity in multiple myeloma
    • Cirstea D, Hideshima T, Rodig S, et al. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bo und-ra pamycin and perifosine induces antitumor activity in multiple myeloma. Mol Cancer Ther, 2010,9:963-975.
    • (2010) Mol Cancer Ther , vol.9 , pp. 963-975
    • Cirstea, D.1    Hideshima, T.2    Rodig, S.3
  • 56
    • 77951165665 scopus 로고    scopus 로고
    • Daunorubicin-lo added magnetic nanoparticles of Fe (3)O (4) greatly enhance the responses of multidrug-re sistant K562 leukemic cells in a nude mouse xenograft model to chemotherapy
    • Lai BB, Chen BA, Cheng J, et al. Daunorubicin-lo added magnetic nanoparticles of Fe (3)O (4) greatly enhance the responses of multidrug-re sistant K562 leukemic cells in a nude mouse xenograft model to chemotherapy. Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2009,17:345-351.
    • (2009) Zhongguo Shi Yan Xue Ye Xue Za Zhi , vol.17 , pp. 345-351
    • Lai, B.B.1    Chen, B.A.2    Cheng, J.3
  • 57
    • 16544390219 scopus 로고    scopus 로고
    • Absorption, distribution, and excretion of DJ-92 7, a novel orally effective taxane, in mice, dogs, and monkeys
    • Ono C, Takao A, Atsumi R. Absorption, distribution, and excretion of DJ-92 7, a novel orally effective taxane, in mice, dogs, and monkeys. Biol Pharm Bull, 2004,27:345-351.
    • (2004) Biol Pharm Bull , vol.27 , pp. 345-351
    • Ono, C.1    Takao, A.2    Atsumi, R.3
  • 58
    • 0038419962 scopus 로고    scopus 로고
    • DJ-92 7, a novel oral taxane, overcomes P-gl ycoprotein-m ediated multidrug resistance in vitro and in vivo
    • Shionoya M, Jimbo T, Kitagawa M, et al. DJ-92 7, a novel oral taxane, overcomes P-gl ycoprotein-m ediated multidrug resistance in vitro and in vivo. Cancer Sci, 2003,94:459-466.
    • (2003) Cancer Sci , vol.94 , pp. 459-466
    • Shionoya, M.1    Jimbo, T.2    Kitagawa, M.3
  • 59
    • 50349093533 scopus 로고    scopus 로고
    • Phase I/II study of a 3 weekly oral taxane (DJ-92 7) in patients with recurrent, advanced non-sm all cell lung cancer
    • Baas P, Szczesna A, Albert I, et al. Phase I/II study of a 3 weekly oral taxane (DJ-92 7) in patients with recurrent, advanced non-sm all cell lung cancer. J Thorac Oncol, 2008,3: 745-750.
    • (2008) J Thorac Oncol , vol.3 , pp. 745-750
    • Baas, P.1    Szczesna, A.2    Albert, I.3
  • 60
    • 1842843197 scopus 로고    scopus 로고
    • Broad- spectrum modulation of ATP-bi nding cassette transport proteins by the taxane derivatives ortataxel (IDN-51 09, BAY 59-88 62) and tRA96023
    • Minderman H, Brooks TA, O'Loughlin KL, et al. Broad- spectrum modulation of ATP-bi nding cassette transport proteins by the taxane derivatives ortataxel (IDN-51 09, BAY 59-88 62) and tRA96023. Cancer Chemother Pharmacol, 2004,53:363-369.
    • (2004) Cancer Chemother Pharmacol , vol.53 , pp. 363-369
    • Minderman, H.1    Brooks, T.A.2    O'Loughlin, K.L.3
  • 61
    • 0036023432 scopus 로고    scopus 로고
    • Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-88 62) on hormone-re fractory prostate cancer
    • Cassinelli G, Lanzi C, Supino R, et al. Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-88 62) on hormone-re fractory prostate cancer. Clin Cancer Res, 2002,8:2647-2654.
    • (2002) Clin Cancer Res , vol.8 , pp. 2647-2654
    • Cassinelli, G.1    Lanzi, C.2    Supino, R.3
  • 62
    • 0035924214 scopus 로고    scopus 로고
    • Synthesis and anti tumor activity of novel C-7 paclitaxel ethers: Discovery of BMS-18 4476
    • Altstadt TJ, Fairchild CR, Golik J, et al. Synthesis and anti tumor activity of novel C-7 paclitaxel ethers: discovery of BMS-18 4476. J Med Chem, 2001,44:4577-4583.
    • (2001) J Med Chem , vol.44 , pp. 4577-4583
    • Altstadt, T.J.1    Fairchild, C.R.2    Golik, J.3
  • 63
    • 20944441476 scopus 로고    scopus 로고
    • Phase II trial of the novel taxane BMS-18 4476 as second-lin e in non-sm all-ce ll lung cancer
    • Camps C, Felip E, Sanchez JM, et al. Phase II trial of the novel taxane BMS-18 4476 as second-lin e in non-sm all-ce ll lung cancer. Ann Oncol, 2005,16:597-601.
    • (2005) Ann Oncol , vol.16 , pp. 597-601
    • Camps, C.1    Felip, E.2    Sanchez, J.M.3
  • 64
    • 3843068912 scopus 로고    scopus 로고
    • Phase I trial of the novel taxane BMS-18 4476 administered in combination with carboplatin every 21 days
    • Bilenker JH, Stevenson JP, Gallagher ML, et al. Phase I trial of the novel taxane BMS-18 4476 administered in combination with carboplatin every 21 days. Br J Cancer, 2004,91:213-218.
    • (2004) Br J Cancer , vol.91 , pp. 213-218
    • Bilenker, J.H.1    Stevenson, J.P.2    Gallagher, M.L.3
  • 65
    • 0033863452 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of a new taxoid, RPR5 109881A, given as a 1-ho ur intravenous infusion in patients with advanced solid tumors
    • Kurata T, Shimada Y, Tamura T, et al. Phase I and pharmacokinetic study of a new taxoid, RPR5 109881A, given as a 1-ho ur intravenous infusion in patients with advanced solid tumors. J Clin Oncol, 2000,18:3164-3171.
    • (2000) J Clin Oncol , vol.18 , pp. 3164-3171
    • Kurata, T.1    Shimada, Y.2    Tamura, T.3
  • 66
    • 0034671296 scopus 로고    scopus 로고
    • Phase I dose-fin ding study of a new taxane, RPR 109881A, administered as a one- hour intravenous infusion days 1 and 8 to patients with advanced solid tumors
    • Gelmon KA, Latreille J, Tolcher A, et al. Phase I dose-fin ding study of a new taxane, RPR 109881A, administered as a one- hour intravenous infusion days 1 and 8 to patients with advanced solid tumors. J Clin Oncol, 2000,18:4098-4108.
    • (2000) J Clin Oncol , vol.18 , pp. 4098-4108
    • Gelmon, K.A.1    Latreille, J.2    Tolcher, A.3
  • 67
    • 0035990845 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic studies of the taxoid derivative RPR 109881A administered as a 1-ho ur or a 3-ho ur infusion in patients with advanced solid tumors
    • Sessa C, Cuvier C, Caldiera S, et al. Phase I clinical and pharmacokinetic studies of the taxoid derivative RPR 109881A administered as a 1-ho ur or a 3-ho ur infusion in patients with advanced solid tumors. Ann Oncol, 2002,13:1140-1150.
    • (2002) Ann Oncol , vol.13 , pp. 1140-1150
    • Sessa, C.1    Cuvier, C.2    Caldiera, S.3
  • 68
    • 66149129222 scopus 로고    scopus 로고
    • Albumin-bo und formulation of paclitaxel (Abraxane ABI-00 7) in the treatment of breast cancer
    • Miele E, Spinelli GP, Tomao F, et al. Albumin-bo und formulation of paclitaxel (Abraxane ABI-00 7) in the treatment of breast cancer. Int J Nanomedicine, 2009,4:99-105.
    • (2009) Int J Nanomedicine , vol.4 , pp. 99-105
    • Miele, E.1    Spinelli, G.P.2    Tomao, F.3
  • 69
    • 33846316084 scopus 로고    scopus 로고
    • Nano particle albumin-bo und paclitaxel (ABI-00 7): A newer taxane alternative in breast cancer
    • Moreno-Aspitia A, Perez EA. Nano particle albumin-bo und paclitaxel (ABI-00 7): a newer taxane alternative in breast cancer. Future Oncol, 2005,1:755-762.
    • (2005) Future Oncol , vol.1 , pp. 755-762
    • Moreno-Aspitia, A.1    Perez, E.A.2
  • 70
    • 79952955367 scopus 로고    scopus 로고
    • Development of EGFR-targeted polymer blend nanocarriers for combination paclitaxel/ lonidamine delivery to treat multi-dr ug resistance in human breast and ovarian tumor cells
    • Milane L, Duan Z, Amiji M. Development of EGFR-targeted polymer blend nanocarriers for combination paclitaxel/ lonidamine delivery to treat multi-dr ug resistance in human breast and ovarian tumor cells. Mol Pharm, 2011,8:185-203.
    • (2011) Mol Pharm , vol.8 , pp. 185-203
    • Milane, L.1    Duan, Z.2    Amiji, M.3
  • 71
    • 77954205948 scopus 로고    scopus 로고
    • Current status of nanotechnology applied in biomedicine
    • Wang YZ, Huang B, Lv J, et al. Current status of nanotechnology applied in biomedicine. Acta Biophys Sin, 2009,25:168
    • (2009) Acta Biophys Sin , vol.25 , pp. 168
    • Wang, Y.Z.1    Huang, B.2    Lv, J.3


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