Differentiation of human induced pluripotent stem cells into functional enterocyte-like cells using a simple method

Drug Metabolism and Pharmacokinetics

Volumn 29, Issue 1, 2014, Pages 44-51

  Iwao, Takahiro ^a   Toyota, Masashi ^b   Miyagawa, Yoshitaka ^b   Okita, Hajime ^b   Kiyokawa, Nobutaka ^b   Akutsu, Hidenori ^b   Umezawa, Akihiro ^b   Nagata, Kiyoshi ^c   Matsunaga, Tamihide ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^c TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Drug metabolizing enzymes; Drug transporters; Enterocytes; Human iPS cells; Intestinal differentiation; Pharmacokinetics

Indexed keywords

ACTIVIN A; CYTOCHROME P450 3A4; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; G PROTEIN COUPLED RECEPTOR KINASE 5; MESSENGER RNA; PEPTIDE TRANSPORTER 1; SUCRASE ISOMALTASE; TRANSCRIPTION FACTOR CDX2; WNT3A PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; ENDODERM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTESTINE CELL; INTESTINE EPITHELIUM CELL; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; BIOLOGICAL MARKERS; CATTLE; CELL DIFFERENTIATION; CELL LINE; COUMARINS; CYTOCHROME P-450 CYP3A; DIPEPTIDES; ERYTHROCYTES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; OLIGO-1,6-GLUCOSIDASE; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; SUCRASE; SYMPORTERS;

EID: 84898488352     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-13-RG-005     Document Type: Article

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