Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells

NeuroToxicology

Volumn 44, Issue , 2014, Pages 140-148

  Rojas Charry, Liliana ^a   Cookson, Mark R ^b   Niño, Andrea ^a   Arboleda, Humberto ^a   Arboleda, Gonzalo ^a  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Ceramide; Mitochondrial dynamics; Parkinson; Pink1; Rotenone

Indexed keywords

CERAMIDE; CYCLIC AMP; DYNAMIN I; MITOFUSIN 2; NEUROTOXIN; PROTEIN SERINE THREONINE KINASE; PTEN INDUCED PUTATIVE KINASE 1; UNCLASSIFIED DRUG; FORSKOLIN; MEMBRANE PROTEIN; PROTEIN DRP1; PROTEIN KINASE; ROTENONE; MITOCHONDRIAL PROTEIN; N-ACETYLSPHINGOSINE; PTEN-INDUCED PUTATIVE KINASE; SPHINGOSINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL FUSION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOWN REGULATION; GENE SILENCING; IMMUNOFLUORESCENCE; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOUSE; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SENSITIZATION; WESTERN BLOTTING; CELLULAR PARAMETERS; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MITOCHONDRIAL FISSION; MITOCHONDRIAL FUSION; MITOCHONDRIAL MORPHOLOGY; NERVE CELL NECROSIS; NEUROTOXICITY; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; DOPAMINERGIC NEURONS; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEIN KINASES; ROTENONE; SPHINGOSINE;

EID: 84903713265     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.04.007     Document Type: Article

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