Aluminium chloride impairs long-term memory and downregulates cAMP-PKA-CREB signalling in rats

Toxicology

Volumn 323, Issue , 2014, Pages 95-108

  Zhang, Lifeng ^a,b   Jin, Cuihong ^a   Lu, Xiaobo ^a   Yang, Jinghua ^a   Wu, Shengwen ^a   Liu, Qiufang ^a   Chen, Rong ^b   Bai, Chunyu ^b   Zhang, Di ^b   Zheng, Linlin ^c   Du, Yanqiu ^d   Cai, Yuan ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b SHENYANG MEDICAL COLLEGE   (China)

^c EASTERN LIAONING UNIVERSITY   (China)

^d Shenyang Ninth People's Hospital   (China)

Author keywords

Aluminium; CAMP PKA CREB; Hippocampus; Long term memory; Ultrastructure

Indexed keywords

ALUMINUM; ALUMINUM CHLORIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DRINKING WATER;

ANIMAL EXPERIMENT; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; COGNITIVE DEFECT; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOWN REGULATION; FEMALE; FLUID INTAKE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LONG TERM MEMORY; LONG TERM POTENTIATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYNAPSE;

ALUMINIUM; CAMP-PKA-CREB; HIPPOCAMPUS; LONG-TERM MEMORY; ULTRASTRUCTURE;

ALUMINUM COMPOUNDS; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHLORIDES; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; FEMALE; HIPPOCAMPUS; MEMORY DISORDERS; MEMORY, LONG-TERM; NEURONS; PREGNANCY; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84903702074     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.06.011     Document Type: Article

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