메뉴 건너뛰기




Volumn 29, Issue 6, 2008, Pages 1069-1079

Aluminium-induced electrophysiological, biochemical and cognitive modifications in the hippocampus of aging rats

Author keywords

Aluminium chloride; Electrophysiology; Hippocampus; Morris water maze; Multiple unit activity; Protein kinase C

Indexed keywords

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALUMINUM; ALUMINUM CHLORIDE; DRINKING WATER; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; PROTEIN KINASE; SUPEROXIDE DISMUTASE;

EID: 56249145473     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2008.08.005     Document Type: Article
Times cited : (115)

References (68)
  • 1
    • 0019728988 scopus 로고
    • 2+ channel and a re-evaluation of the role of sodium/calcium exchange
    • 2+ channel and a re-evaluation of the role of sodium/calcium exchange. Eur J Biochem 117 (1981) 491-497
    • (1981) Eur J Biochem , vol.117 , pp. 491-497
    • Akerman, K.E.O.1    Nicholls, D.G.2
  • 2
    • 0023043778 scopus 로고
    • Translocation of protein kinase C activity may mediate hippocampal long-term potentiation
    • Akers R.F., Lovinger D.M., Colley P.A., Linden D.J., and Rottenberg A. Translocation of protein kinase C activity may mediate hippocampal long-term potentiation. Science 231 (1986) 587-589
    • (1986) Science , vol.231 , pp. 587-589
    • Akers, R.F.1    Lovinger, D.M.2    Colley, P.A.3    Linden, D.J.4    Rottenberg, A.5
  • 3
    • 0024313736 scopus 로고
    • Aluminum induced neurotoxicity: alteration in membrane function at the blood brain barrier
    • Banks W.A., and Kastin A.J. Aluminum induced neurotoxicity: alteration in membrane function at the blood brain barrier. Neurosci Biobehav Rev 13 (1989) 47-53
    • (1989) Neurosci Biobehav Rev , vol.13 , pp. 47-53
    • Banks, W.A.1    Kastin, A.J.2
  • 4
    • 0024121542 scopus 로고
    • Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells
    • Banks B., DeWeer A., Kusian A.M., Rasmussen H., and Alkon D.L. Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells. Proc Natl Acad Sci USA 85 (1988) 1988-1992
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1988-1992
    • Banks, B.1    DeWeer, A.2    Kusian, A.M.3    Rasmussen, H.4    Alkon, D.L.5
  • 5
    • 0027476024 scopus 로고
    • A synaptic model of memory: long term potentiation in the hippocampus
    • Bliss T.V.P., and Collingridge G.L. A synaptic model of memory: long term potentiation in the hippocampus. Nature 361 (1993) 31-39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 7
    • 0031912255 scopus 로고    scopus 로고
    • Mechanisms underlying the aluminum-induced potentiation of the pro-oxidant properties of transition metals
    • Bondy S.C., Guo-Ross S.X., and Pien J. Mechanisms underlying the aluminum-induced potentiation of the pro-oxidant properties of transition metals. Neurotoxicology 19 (1998) 65-71
    • (1998) Neurotoxicology , vol.19 , pp. 65-71
    • Bondy, S.C.1    Guo-Ross, S.X.2    Pien, J.3
  • 8
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye binding. Anal Biochem 72 (1976) 248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 9
    • 0036710928 scopus 로고    scopus 로고
    • Lipofuscin: mechanisms of age-related accumulation and influence on cell function
    • Brunk U.T., and Terman A. Lipofuscin: mechanisms of age-related accumulation and influence on cell function. Free Radic Biol Med 33 (2002) 611-619
    • (2002) Free Radic Biol Med , vol.33 , pp. 611-619
    • Brunk, U.T.1    Terman, A.2
  • 12
    • 0027568438 scopus 로고
    • Oxygen, antioxidants and brain dysfunction
    • Choi B.H. Oxygen, antioxidants and brain dysfunction. Yonsei Med J 34 (1993) 1-10
    • (1993) Yonsei Med J , vol.34 , pp. 1-10
    • Choi, B.H.1
  • 14
    • 0035138149 scopus 로고    scopus 로고
    • Ultrastructural study of rat hippocampus after chronic administration of aluminium l-glutamate: an acceleration of aging process
    • Deloncle R., Huguet E., Fernandez B., Quellard N., Babin P.H., and Guillard O. Ultrastructural study of rat hippocampus after chronic administration of aluminium l-glutamate: an acceleration of aging process. Exp. Gerontol 36 (2001) 234-244
    • (2001) Exp. Gerontol , vol.36 , pp. 234-244
    • Deloncle, R.1    Huguet, E.2    Fernandez, B.3    Quellard, N.4    Babin, P.H.5    Guillard, O.6
  • 15
    • 0020688960 scopus 로고
    • The calcium pump and sodium calcium exchange in squid axons
    • Dipolo R., and Beague L. The calcium pump and sodium calcium exchange in squid axons. Annu Rev Physiology 45 (1983) 313-324
    • (1983) Annu Rev Physiology , vol.45 , pp. 313-324
    • Dipolo, R.1    Beague, L.2
  • 18
    • 0000154206 scopus 로고
    • The colorimetric determination of phosphorus
    • Fiske C.H., and Subbarow J. The colorimetric determination of phosphorus. J Biol Chem 66 (1925) 375-400
    • (1925) J Biol Chem , vol.66 , pp. 375-400
    • Fiske, C.H.1    Subbarow, J.2
  • 19
    • 0035872417 scopus 로고    scopus 로고
    • Aluminium as a risk factor for Alzheimer's disease with emphasis on drinking water
    • Flaten T.P. Aluminium as a risk factor for Alzheimer's disease with emphasis on drinking water. Brain Res Bull 55 (2001) 187-196
    • (2001) Brain Res Bull , vol.55 , pp. 187-196
    • Flaten, T.P.1
  • 20
    • 0021288821 scopus 로고
    • Assay of glutathione peroxidase
    • Academic Press, New York pp. 114-21
    • Flohe L., and Gunzler W.A. Assay of glutathione peroxidase. Methods of enzymology (1984), Academic Press, New York pp. 114-21
    • (1984) Methods of enzymology
    • Flohe, L.1    Gunzler, W.A.2
  • 22
    • 0028798771 scopus 로고
    • Concerning the role of aluminum in causing dementia
    • Forbes W.F., Gentleman J.F., and Maxwell C.J. Concerning the role of aluminum in causing dementia. Exp Gerontol 30 1 (1995) 23-32
    • (1995) Exp Gerontol , vol.30 , Issue.1 , pp. 23-32
    • Forbes, W.F.1    Gentleman, J.F.2    Maxwell, C.J.3
  • 23
    • 0027177629 scopus 로고
    • Effects of aging on spatial learning and hippocampal protein kinase C in mice
    • Fordyce D.E., and Wehner J.M. Effects of aging on spatial learning and hippocampal protein kinase C in mice. Neurobiol Aging 14 4 (1993) 309-317
    • (1993) Neurobiol Aging , vol.14 , Issue.4 , pp. 309-317
    • Fordyce, D.E.1    Wehner, J.M.2
  • 24
    • 0029981453 scopus 로고    scopus 로고
    • In vitro exposure to aluminum does not alter long-term potentiation or glutamate release in rat hippocampal slices
    • Gilbert M.E., and Shafer T.J. In vitro exposure to aluminum does not alter long-term potentiation or glutamate release in rat hippocampal slices. Neurotoxicol Teratol 18 2 (1996) 175-180
    • (1996) Neurotoxicol Teratol , vol.18 , Issue.2 , pp. 175-180
    • Gilbert, M.E.1    Shafer, T.J.2
  • 25
    • 0033390380 scopus 로고    scopus 로고
    • Aluminum uptake and effects on transferrin mediated iron uptake in primary cultures of rat neurons, astrocytes and oligodendrocytes
    • Golub M.S., Han B., and Keen C.L. Aluminum uptake and effects on transferrin mediated iron uptake in primary cultures of rat neurons, astrocytes and oligodendrocytes. Neurotoxicology 20 6 (1999) 961-970
    • (1999) Neurotoxicology , vol.20 , Issue.6 , pp. 961-970
    • Golub, M.S.1    Han, B.2    Keen, C.L.3
  • 26
    • 0034190297 scopus 로고    scopus 로고
    • Protein kinase C signaling and oxidative stress
    • Gopalakrishna R., and Jaken S. Protein kinase C signaling and oxidative stress. Free Radic Biol Med 28 (2000) 1349-1361
    • (2000) Free Radic Biol Med , vol.28 , pp. 1349-1361
    • Gopalakrishna, R.1    Jaken, S.2
  • 27
    • 0016275313 scopus 로고
    • Glutathione S-transferases: the first enzymatic step in mercapturic acid formation
    • Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. J Biol Chem 249 (1974) 7130-7138
    • (1974) J Biol Chem , vol.249 , pp. 7130-7138
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 28
    • 0002211163 scopus 로고
    • Calcium-dependent protein kinase in pea shoot membranes
    • Hetherington A., and Trewavas A. Calcium-dependent protein kinase in pea shoot membranes. FEBS Lett. 145 (1982) 67-71
    • (1982) FEBS Lett. , vol.145 , pp. 67-71
    • Hetherington, A.1    Trewavas, A.2
  • 29
    • 0030051506 scopus 로고    scopus 로고
    • Altered calcium homeostasis: a possible mechanism of aluminium-induced neurotoxicity
    • Julka D., and Gill K.D. Altered calcium homeostasis: a possible mechanism of aluminium-induced neurotoxicity. Biochim Biophys Acta 1315 (1996) 47-54
    • (1996) Biochim Biophys Acta , vol.1315 , pp. 47-54
    • Julka, D.1    Gill, K.D.2
  • 30
    • 33744972325 scopus 로고    scopus 로고
    • Neuroprotective role of Bacopa monniera extract against aluminium-induced oxidative stress in the hippocampus of rat brain
    • Jyoti A., and Sharma D. Neuroprotective role of Bacopa monniera extract against aluminium-induced oxidative stress in the hippocampus of rat brain. Neurotoxicology 27 4 (2006) 451-457
    • (2006) Neurotoxicology , vol.27 , Issue.4 , pp. 451-457
    • Jyoti, A.1    Sharma, D.2
  • 31
    • 33947595778 scopus 로고    scopus 로고
    • Bacopa monniera prevents from aluminium neurotoxicity in the cerebral cortex of rat brain
    • Jyoti A., Sethi P., and Sharma D. Bacopa monniera prevents from aluminium neurotoxicity in the cerebral cortex of rat brain. J Ethnopharmacol 111 April 20 (1) (2007) 56-62
    • (2007) J Ethnopharmacol , vol.111 , Issue.April 20 1 , pp. 56-62
    • Jyoti, A.1    Sethi, P.2    Sharma, D.3
  • 32
    • 1442349252 scopus 로고    scopus 로고
    • Aluminium induced enhancement of ageing-related biochemical and electrophysiological parameters in rat brain regions
    • Kaur J., Singh S., Sharma D., and Singh R. Aluminium induced enhancement of ageing-related biochemical and electrophysiological parameters in rat brain regions. Indian J Biochem Biophys 40 (2003) 330-339
    • (2003) Indian J Biochem Biophys , vol.40 , pp. 330-339
    • Kaur, J.1    Singh, S.2    Sharma, D.3    Singh, R.4
  • 33
    • 0037648874 scopus 로고    scopus 로고
    • Neurostimulatory and antioxidative effects of l-deprenyl in aged rat brain regions
    • Kaur J., Singh S., Sharma D., and Singh R. Neurostimulatory and antioxidative effects of l-deprenyl in aged rat brain regions. Biogerontology 4 2 (2003) 105-111
    • (2003) Biogerontology , vol.4 , Issue.2 , pp. 105-111
    • Kaur, J.1    Singh, S.2    Sharma, D.3    Singh, R.4
  • 34
    • 31044448563 scopus 로고    scopus 로고
    • Neurofilament phosphorylation and disruption: a possible mechanism of chronic aluminium toxicity in Wistar rats
    • Kaur A., Joshi K., Minz R.W., and Gill K.D. Neurofilament phosphorylation and disruption: a possible mechanism of chronic aluminium toxicity in Wistar rats. Toxicology 219 (2006) 1-10
    • (2006) Toxicology , vol.219 , pp. 1-10
    • Kaur, A.1    Joshi, K.2    Minz, R.W.3    Gill, K.D.4
  • 35
    • 32444450650 scopus 로고    scopus 로고
    • Effects of aluminum on the nervous system and its possible link with neurodegenerative diseases
    • Kawahara M. Effects of aluminum on the nervous system and its possible link with neurodegenerative diseases. J Alzheimers Dis 8 2 (2005) 171-182
    • (2005) J Alzheimers Dis , vol.8 , Issue.2 , pp. 171-182
    • Kawahara, M.1
  • 36
    • 0343714604 scopus 로고    scopus 로고
    • Ligand specific effects on aluminum incorporation and toxicity in neurons and astrocytes
    • Levesque L., Mizzen C.A., McLachlan D.R., and Fraser P.E. Ligand specific effects on aluminum incorporation and toxicity in neurons and astrocytes. Brain Res 877 (2000) 191-202
    • (2000) Brain Res , vol.877 , pp. 191-202
    • Levesque, L.1    Mizzen, C.A.2    McLachlan, D.R.3    Fraser, P.E.4
  • 37
    • 0028012436 scopus 로고
    • The hippocampal CA3 network: an invivo intracellular labeling study
    • Li X.G., Somogyi P., Ylinen A., and Buzsaki G. The hippocampal CA3 network: an invivo intracellular labeling study. J Comp Neurol 339 (1994) 181-208
    • (1994) J Comp Neurol , vol.339 , pp. 181-208
    • Li, X.G.1    Somogyi, P.2    Ylinen, A.3    Buzsaki, G.4
  • 38
    • 11844255361 scopus 로고    scopus 로고
    • Neurochemical and behavioral effects of the intrahippocampal co-injection of h-amyloid protein 1-40 and Ibotenic acid in rats
    • Li Y., Qin H., Chen Q.S., and Wang J.J. Neurochemical and behavioral effects of the intrahippocampal co-injection of h-amyloid protein 1-40 and Ibotenic acid in rats. Life Sci 76 (2005) 1189-1197
    • (2005) Life Sci , vol.76 , pp. 1189-1197
    • Li, Y.1    Qin, H.2    Chen, Q.S.3    Wang, J.J.4
  • 39
    • 0016272750 scopus 로고
    • Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S., and Marklund G. Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47 (1974) 469-474
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 40
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 11 1 (1984) 47-60
    • (1984) J Neurosci Methods , vol.11 , Issue.1 , pp. 47-60
    • Morris, R.1
  • 41
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95 (1979) 351-355
    • (1979) Anal Biochem , vol.95 , pp. 351-355
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 42
    • 0026542824 scopus 로고
    • Identification of two distinct populations of protein kinase C in rat brain membranes
    • Orr N., Yavin E., and Lester D.S. Identification of two distinct populations of protein kinase C in rat brain membranes. J Neurochem 58 2 (1992) 461-470
    • (1992) J Neurochem , vol.58 , Issue.2 , pp. 461-470
    • Orr, N.1    Yavin, E.2    Lester, D.S.3
  • 43
    • 0027301756 scopus 로고
    • Aluminum has both oxidant and antioxidant effects in mouse brain membranres
    • Oteiza P.I., Fraga C.G., and Keen C.L. Aluminum has both oxidant and antioxidant effects in mouse brain membranres. Arch Biochem Biophys 300 (1993) 517-521
    • (1993) Arch Biochem Biophys , vol.300 , pp. 517-521
    • Oteiza, P.I.1    Fraga, C.G.2    Keen, C.L.3
  • 44
    • 22144451818 scopus 로고    scopus 로고
    • Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats
    • Ozdemir D., Tugyan K., Uysal N., Sonmezb U., Sonmezc A., Acikgoz O., et al. Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats. Neurosci Lett 385 (2005) 234-239
    • (2005) Neurosci Lett , vol.385 , pp. 234-239
    • Ozdemir, D.1    Tugyan, K.2    Uysal, N.3    Sonmezb, U.4    Sonmezc, A.5    Acikgoz, O.6
  • 46
    • 0028671805 scopus 로고
    • 3+ on voltage-activated calcium channel currents
    • 3+ on voltage-activated calcium channel currents. Cell Mol Neurobiol 14 6 (1994) 831-840
    • (1994) Cell Mol Neurobiol , vol.14 , Issue.6 , pp. 831-840
    • Platt, B.1    Büsselberg, D.2
  • 47
    • 0028674260 scopus 로고
    • Actions of aluminium on voltage-activated calcium channel currents
    • Platt B., and Büsselberg D. Actions of aluminium on voltage-activated calcium channel currents. Cell Mol Neurobiol 14 6 (1994) 819-829
    • (1994) Cell Mol Neurobiol , vol.14 , Issue.6 , pp. 819-829
    • Platt, B.1    Büsselberg, D.2
  • 48
    • 0028126616 scopus 로고
    • Aluminium reduces glutamate activated currents of rat hippocampal neurons
    • Platt B., Haas H.L., and Büsselberg D. Aluminium reduces glutamate activated currents of rat hippocampal neurons. Neuroreport 5 (1994) 2329-2332
    • (1994) Neuroreport , vol.5 , pp. 2329-2332
    • Platt, B.1    Haas, H.L.2    Büsselberg, D.3
  • 49
    • 0029123436 scopus 로고
    • Aluminium impairs hippocampal long term potentiation in rats in vitro and in vivo
    • Platt B., Carpenter C., Büsselberg D., Reymann K.G., and Riedel G. Aluminium impairs hippocampal long term potentiation in rats in vitro and in vivo. Exp Neurol 134 (1995) 73-86
    • (1995) Exp Neurol , vol.134 , pp. 73-86
    • Platt, B.1    Carpenter, C.2    Büsselberg, D.3    Reymann, K.G.4    Riedel, G.5
  • 50
    • 0035872430 scopus 로고    scopus 로고
    • Aluminum toxicity in the rat brain: histochemical and immunocytochemical evidences
    • Platt B., Fiddler G., Riedel G., and Henderson Z. Aluminum toxicity in the rat brain: histochemical and immunocytochemical evidences. Brain Res Bull 55 (2001) 257-267
    • (2001) Brain Res Bull , vol.55 , pp. 257-267
    • Platt, B.1    Fiddler, G.2    Riedel, G.3    Henderson, Z.4
  • 51
    • 17944397032 scopus 로고    scopus 로고
    • Reversible neural inactivation reveals hippocampal participation in several memory processes
    • Reidel G., Micheau J., Lam A.G., Roloff E., Martin H., Hoz L., et al. Reversible neural inactivation reveals hippocampal participation in several memory processes. Nat Neurosci 2 (1999) 898-905
    • (1999) Nat Neurosci , vol.2 , pp. 898-905
    • Reidel, G.1    Micheau, J.2    Lam, A.G.3    Roloff, E.4    Martin, H.5    Hoz, L.6
  • 52
    • 0027501276 scopus 로고
    • Differential metabolic and electrical activity in the somatic sensory cortex of juvenile and adult rats
    • Riddle D.R., Gutierrez G., Zheng D., White L.E., Richards A., and Purves D. Differential metabolic and electrical activity in the somatic sensory cortex of juvenile and adult rats. J Neurosci 13 (1993) 4193-4213
    • (1993) J Neurosci , vol.13 , pp. 4193-4213
    • Riddle, D.R.1    Gutierrez, G.2    Zheng, D.3    White, L.E.4    Richards, A.5    Purves, D.6
  • 54
    • 0027265521 scopus 로고
    • Age-related decline in multiple unit action potentials of CA3 region of rat hippocampus: correlation with lipid peroxidation and lipofuscin concentration and the effect of centrophenoxine
    • Sharma D., Maurya A.K., and Singh R. Age-related decline in multiple unit action potentials of CA3 region of rat hippocampus: correlation with lipid peroxidation and lipofuscin concentration and the effect of centrophenoxine. Neurobiol Aging 14 (1993) 319-330
    • (1993) Neurobiol Aging , vol.14 , pp. 319-330
    • Sharma, D.1    Maurya, A.K.2    Singh, R.3
  • 55
    • 56249133057 scopus 로고    scopus 로고
    • Electrophysiological ageing of the brain and pharmacology of ageing
    • Thakur M.K., and Prasad S. (Eds), Narosa Publishing House, New Delhi, India
    • Singh R., and Sharma D. Electrophysiological ageing of the brain and pharmacology of ageing. In: Thakur M.K., and Prasad S. (Eds). Molecular and Cellular Neurobiology (2005), Narosa Publishing House, New Delhi, India 135-151
    • (2005) Molecular and Cellular Neurobiology , pp. 135-151
    • Singh, R.1    Sharma, D.2
  • 58
    • 0032958070 scopus 로고    scopus 로고
    • Neuroprotective effects of brain derived neurotrophic factor in seizures during development
    • Tandon P., Yang Y., Das K., Holmes G.L., and Stafstrom C.E. Neuroprotective effects of brain derived neurotrophic factor in seizures during development. Neuroscience 91 (1999) 293-303
    • (1999) Neuroscience , vol.91 , pp. 293-303
    • Tandon, P.1    Yang, Y.2    Das, K.3    Holmes, G.L.4    Stafstrom, C.E.5
  • 59
    • 0031596124 scopus 로고    scopus 로고
    • A receptors by aluminum
    • A receptors by aluminum. J Neurophysiol 80 (1998) 755-761
    • (1998) J Neurophysiol , vol.80 , pp. 755-761
    • Trombley, P.Q.1
  • 60
    • 0027976985 scopus 로고
    • Glycine exerts potent inhibitory actions on mammalian olfactory bulb neurons
    • Trombley P.Q., and Shepherd G.M. Glycine exerts potent inhibitory actions on mammalian olfactory bulb neurons. J Neurophysiol 71 (1994) 761-767
    • (1994) J Neurophysiol , vol.71 , pp. 761-767
    • Trombley, P.Q.1    Shepherd, G.M.2
  • 61
    • 0027430035 scopus 로고
    • Structure-function relationships of cation binding in the Na+/K(+)-ATPase
    • Vasilets L.A., and Schwarz W. Structure-function relationships of cation binding in the Na+/K(+)-ATPase. Biochim Biophys Acta 1154 (1993) 201-222
    • (1993) Biochim Biophys Acta , vol.1154 , pp. 201-222
    • Vasilets, L.A.1    Schwarz, W.2
  • 62
    • 0025351941 scopus 로고
    • Upchurch. Hippocampal protein kinase C activity is reduced in poor spatial learners
    • Wehner J.M., and Sleight S. Upchurch. Hippocampal protein kinase C activity is reduced in poor spatial learners. Brain Res 523 (1990) 181-187
    • (1990) Brain Res , vol.523 , pp. 181-187
    • Wehner, J.M.1    Sleight, S.2
  • 63
    • 0027082739 scopus 로고
    • Brain aluminum in Alzheimer's disease using an improved GFAAS method
    • Xu N., Majidi V., Markesbery W.R., and Ehmann W.D. Brain aluminum in Alzheimer's disease using an improved GFAAS method. Neurotoxicology 13 (1992) 735-744
    • (1992) Neurotoxicology , vol.13 , pp. 735-744
    • Xu, N.1    Majidi, V.2    Markesbery, W.R.3    Ehmann, W.D.4
  • 64
    • 0026454505 scopus 로고
    • Calcium, magnesium and aluminum concentrations in Parkinson's disease
    • Yasui M., Kihira T., and Ota K. Calcium, magnesium and aluminum concentrations in Parkinson's disease. Neurotoxicology 13 (1992) 593-600
    • (1992) Neurotoxicology , vol.13 , pp. 593-600
    • Yasui, M.1    Kihira, T.2    Ota, K.3
  • 65
    • 0033660022 scopus 로고    scopus 로고
    • The toxicology of aluminum in the brain: a review
    • Yokel R.A. The toxicology of aluminum in the brain: a review. Neurotoxicology 21 (2000) 813-828
    • (2000) Neurotoxicology , vol.21 , pp. 813-828
    • Yokel, R.A.1
  • 66
    • 0028071281 scopus 로고
    • Activation of acetylcholinesterase by aluminium(III): the relevance of the metal species
    • Zatta P., Zambenedetti P., Bruna V., and Filippi B. Activation of acetylcholinesterase by aluminium(III): the relevance of the metal species. Neuroreport 5 (1994) 1777-1780
    • (1994) Neuroreport , vol.5 , pp. 1777-1780
    • Zatta, P.1    Zambenedetti, P.2    Bruna, V.3    Filippi, B.4
  • 67
    • 0037107889 scopus 로고    scopus 로고
    • In vivo and in vitro effects of aluminum on the activity of mouse brain acetylcholinesterase
    • Zatta P., Ibn-Lkhayat-Idrissi M., Zambenedetti P., Kilyen M., and Kiss T. In vivo and in vitro effects of aluminum on the activity of mouse brain acetylcholinesterase. Brain Res Bull 59 (2002) 41-45
    • (2002) Brain Res Bull , vol.59 , pp. 41-45
    • Zatta, P.1    Ibn-Lkhayat-Idrissi, M.2    Zambenedetti, P.3    Kilyen, M.4    Kiss, T.5
  • 68
    • 3042561487 scopus 로고    scopus 로고
    • Effects of aluminum chloride on sodium current, transient outward potassium current and delayed rectifier potassium current in acutely isolated rat hippocampal CA1 neurons
    • Zhang B., Nie A., Bai W., and Meng Z. Effects of aluminum chloride on sodium current, transient outward potassium current and delayed rectifier potassium current in acutely isolated rat hippocampal CA1 neurons. Food Chem Toxicol 42 (2004) 1453-1462
    • (2004) Food Chem Toxicol , vol.42 , pp. 1453-1462
    • Zhang, B.1    Nie, A.2    Bai, W.3    Meng, Z.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.