Estimating influence of cofragmentation on peptide quantification and identification in itraq experiments by simulating multiplexed spectra

Journal of Proteome Research

Volumn 13, Issue 7, 2014, Pages 3488-3497

  Li, Honglan ^a   Hwang, Kyu Baek ^a   Mun, Dong Gi ^b   Kim, Hokeun ^b   Lee, Hangyeore ^b   Lee, Sang Won ^b   Paek, Eunok ^c  

^a Soongsil University   (South Korea)

^b Korea University   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

cofragmentation; differentially expressed peptides; isobaric tag based quantification; iTRAQ; multiplexed spectra; peptide quantification; simulation

Indexed keywords

DIFFERENTIALLY EXPRESSED PEPTIDE; PEPTIDE; UNCLASSIFIED DRUG; PEPTIDE FRAGMENT; PROTEOME;

ANALYTIC METHOD; ARTICLE; CANCER TISSUE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; ISOBARIC TAGS FOR RELATIVE AND ABSOLUTE QUANTIFICATION; LIQUID CHROMATOGRAPHY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; STOMACH CANCER; TANDEM MASS SPECTROMETRY; AMINO ACID SEQUENCE; CHEMISTRY; COMPUTER SIMULATION; METABOLISM; MOLECULAR GENETICS; PEPTIDE MAPPING; PROTEIN DEGRADATION; STOMACH TUMOR;

AMINO ACID SEQUENCE; COMPUTER SIMULATION; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEOLYSIS; PROTEOME; PROTEOMICS; STOMACH NEOPLASMS; TANDEM MASS SPECTROMETRY;

EID: 84903697568     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr500060d     Document Type: Article

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