Co-assessment of cell cycle and micronucleus frequencies demonstrates the influence of serum on the in vitro genotoxic response to amorphous monodisperse silica nanoparticles of varying sizes

Nanotoxicology

Volumn 8, Issue 8, 2014, Pages 876-884

  Gonzalez, Laetitia ^a   Lukamowicz Rajska, Magdalena ^b   Thomassen, Leen C J ^c   Kirschhock, Christine E A ^c   Leyns, Luc ^a   Lison, Dominique ^d   Martens, Johan A ^c   Elhajouji, Azeddine ^b   Kirsch Volders, Micheline ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Department of M2S   (Belgium)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Flow cytometry; in vitro micronucleus assay; Serum influence

Indexed keywords

NANOPARTICLE; SILICA NANOPARTICLE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL CYCLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CARCINOMA; MICRONUCLEUS; MICRONUCLEUS TEST; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; S PHASE CELL CYCLE CHECKPOINT; SERUM; ANALYSIS OF VARIANCE; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CULTURE MEDIUM; DRUG EFFECT; MUTAGEN TESTING; TUMOR CELL LINE;

ANALYSIS OF VARIANCE; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; FLOW CYTOMETRY; HUMANS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENICITY TESTS; NANOPARTICLES; PARTICLE SIZE; SERUM; SILICON DIOXIDE;

EID: 84899446179     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2013.842266     Document Type: Article

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