The role of potassium channel in silica nanoparticle-induced inflammatory effect in human vascular endothelial cells in vitro

Toxicology Letters

Volumn 223, Issue 1, 2013, Pages 16-24

  Yang, Li ^a   Yan, Qinqian ^a   Zhao, Jing ^a   Li, Jun ^a   Zong, Xuecong ^a   Yang, Lei ^a   Wang, Zhenglun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Human vascular endothelial cells; Inflammation; Patch clamp; Potassium channel; Silica nanoparticle

Indexed keywords

INTERLEUKIN 6; LACTATE DEHYDROGENASE; MARGATOXIN; POTASSIUM CHANNEL; SILICON DIOXIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; IC 50; IN VITRO STUDY; INFLAMMATION; POTASSIUM CURRENT; PRIORITY JOURNAL; SURVIVAL RATE; UMBILICAL VEIN ENDOTHELIAL CELL;

HUMAN VASCULAR ENDOTHELIAL CELLS; INFLAMMATION; PATCH CLAMP; POTASSIUM CHANNEL; SILICA NANOPARTICLE;

CELL SURVIVAL; ENDOTHELIUM, VASCULAR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-6; L-LACTATE DEHYDROGENASE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; SILICON DIOXIDE; TUMOR NECROSIS FACTOR-ALPHA; VASCULITIS;

EID: 84884266170     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.08.017     Document Type: Article

References (47)

1. Arlehamn C.S., Pétrilli V., Gross O., Tschopp J., Evans T.J. The role of potassium in inflammasome activation by bacteria. J. Biol. Chem. 2010, 285(14):10508-10518.
2. Baranowska M., Kozłowska H., Korbut A., Malinowska B. Potassium channels in blood vessels: their role in health and disease. Postepy. Hig. Med. Dosw. 2007, 61:596-605.
3. Baun A., Hartmann N.B., Grieger K., Kusk K.O. Ecotoxicity of engineered nanoparticles to aquatic invertebrates: a brief review and recommendations for future toxicity testing. Ecotoxicology 2008, 17(5):387-395.
4. Beeton C., Wulff H., Standifer N.E., Azam P., Mullen K.M., Pennington M.W., Kolski-Andreaco A., Wei E., Grino A., Counts D.R., Wang P.H., LeeHealey C.J., S Andrews B., Sankaranarayanan A., Homerick D., Roeck W.W., Tehranzadeh J., Stanhope K.L., Zimin P., Havel P.J., Griffey S., Knaus H.G., Nepom G.T., Gutman G.A., Calabresi P.A., Chandy K.G. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc. Natl. Acad. Sci. U. S. A. 2006, 103(46):17414-17419.
5. Carta S., Tassi S., Semino C., Fossati G., Mascagni P., Dinarello C.A., Rubartelli A. Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules. Blood 2006, 108(5):1618-1626.
6. Delfino R.J., Sioutas C., Malik S. Potential role of ultrafine particles in associations between airborne mass and cardiovascular health. Environ. Health. Perspect. 2005, 113(8):934-946.
7. Donaldson K., Brown D., Clouter A., Duffin R., MacNee W., Renwick L., Tran L., Stone V. The pulmonary toxicology of ultrafine particles. Aerosol. Med. 2002, 15(2):213-220.
8. Dostert C., Pétrilli V., Van Bruggen R., Steele C., Mossman B.T., Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008, 320(5876):674-677.
9. Driscoll K.E. TNF-α and MIP-2: role in particle-induced inflammation and regulation by oxidative stress. Toxicol. Lett. 2000, 112-113:177-183.
10. Fan J., Walsh K.B. Mechanical stimulation regulates voltage-gated potassium currents in cardiac microvascular endothelial cells. Cir. Res. 1999, 84(4):451-457.
11. Garcia-Calvo M., Leonard R.J., Novick J., Stevens S.P., Schmalhofer W., Kaczorowski G.J., Garcia M.L. Purification, characterization, and biosynthesis of margatoxin, a component of Centruroides margaritatus venom that selectively inhibits voltage-dependent potassium channels. J. Biol. Chem. 1993, 268(25):18866-18874.
12. Gojova A., Lee J.T., Jung H.S., Guo B., Barakat A.I., Kennedy I.M. Effect of cerium oxide nanoparticles on inflammation in vascular endothelial cells. Inhal. Toxicol. 2009, 1(Suppl.):123-130.
13. Hamill O.P., Marty A., Neher E., Sakmann B., Sigworth F.J. Improved patch-clamp techniques for high-resolution current reording from cells and cell-free membrane patches. Pflugers Arch. 1981, 391(2):85-100.
14. + current profiles. Lung 2002, 180(4):203-214.
15. Horn R., Marty A. Muscarinic activation of ionic currents measured by a new whole-cell recording method. J. Gen. Physiol. 1988, 92(2):145-159.
16. - concentrations and membrane potential in human monocytes. Biochim. Biophys. Acta 1987, 905(1):195-204.
17. Kahlenberg J.M., Dubyak G.R. Differing caspase-1 activation states in monocyte versus macrophages models of IL-1beta processing and release. J. Leukoc. Biol. 2004, 76(3):676-684.
18. Kishimoto T., Oguri T., Yamabe S., Tada M. Effect of cadmium injury on growth and migration of cultured human vascular endothelial cells. Hum Cell 1996, 9(1):43-48.
19. Kreyling W.G., Semmler M., Erbe F., Mayer P., Takenaka S., Schulz H., Oberdörster G., Ziesenis A. Translocation of ultrafine insoluble iridium particles from lung epithelium to extrapulmonary organs is sizedependent but very low. J. Toxicol. Environ. Health A 2002, 65(20):1513-1530.
20. Lin W., Huang Y.W., Zhou X.D., Ma Y. In vitro toxicity of silica nanoparticles in human lung cancer cells. Toxicol. Appl. Pharmacol. 2006, 217(3):252-259.
21. Lu C.W., Hung Y., Hsiao J.K., Yao M., Chung T.H.R.S., Lin Y.S., Wu S.H.R.S., Hsu S.C., Liu H.R.S.M., Mou C.Y., Yang C.S., Huang D.M., Chen Y.C. Bifunctional magnetic silica nanoparticles for highly efficient human stem cell labeling. Nano. Lett. 2007, 7:149-154.
22. Lukyanenko V., Katina I.E., Nasledov G.A., Terentyev D.A. Pharmacological analysis of voltage-dependent potassium currents in cultured skeletal myocytes of the frog Rana temporaria. Gen. Physiol. Biophys. 1995, 14(6):525-534.
23. Lukyanenko V.I., Katina I.E., Nasledov G.A., Lonsky A.V. Voltage dependent ionic currents in frog cultured skeletal myocytes. Gen. Physiol. Biophys. 1993, 12(3):231-247.
24. Martinon F., Burns K., Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of pro-IL-beta. Mol. Cell. 2002, 10(2):417-426.
25. Martinon F., Mayor A., Tschopp J. The inflammasomes: guardians of the body. Annu. Rev. Immunol. 2009, 27:229-265.
26. Mathie A., Wooltorton J.R., Watkins C.S. Voltage-activated potassium channels in mammalian neurons and their block by novel pharmacological agents. Gen. Pharmacol. 1998, 30(1):13-24.
27. Millar I.D., Wang S., Brown P.D., Barrand M.A., Hladky S.B. Kv1 and Kir2 potassium channels are expressed in rat brain endothelial cells. Pflugers. Arch. 2008, 456(2):379-391.
28. Muñoz-Planillo R., Franchi L., Miller L.S., Núñez G. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J. Immunol. 2009, 183(6):3942-3948.
29. Nakamura M., Shono M., Ishimura K. Synthesis, characterization, and biological applications of multifluorescent silica nanoparticles. Anal. Chem. 2007, 79:6507-6514.
30. Nilius B., Droogmans G. Ion channels and their functional role in vascular endothelium. Physiol. Rev. 2001, 81(4):1416-1447.
31. Oberdörster G., Maynard A., Donaldson K., Castranova V., Fitzpatrick J., Ausman K., Carter J., Karn B., Kreyling W., Lai D., Olin S., Monteiro-Riviere N., Warheit D., Yang H. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part. Fibre. Toxicol. 2005, 2:8.
32. Oberdörster G., Sharp Z., Atudorei V., Elder A., Gelein R., Kreyling W., Cox C. Translocation of inhaled ultrafine particles to the brain. Inhal. Toxicol. 2004, 16(6-7):437-445.
33. Ow H.R.S., Larson D.R., Srivastava M., Baird B.A., Webb W.W., Wiesner U. Bright and stable core-shell fluorescent silica nanoparticles. Nano Lett. 2005, 5:113-117.
34. Paino I.M., Marangoni V.S., de Oliveira Rde C., Antunes L.M., Zucolotto V. Cyto and genotoxicity of gold nanoparticles in human hepatocellular carcinoma and peripheral blood mononuclear cells. Toxicol. Lett. 2010, 215(2):119-125.
35. Pétrilli V., Papin S., Dostert C., Mayor A., Martinon F., Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell. Death. Differ. 2007, 14(9):1583-1589.
36. Qiu M.R., Campbell T.J., Breit S.N. A potassium ion channel is involved in cytokine production by activated human macrophages. Clin. Exp. Immunol. 2002, 130(1):67-74.
37. Sayes C.M., Reed K.L., Warheit D.B. Nanoparticle toxicology: measurements of pulmonary hazard effects following exposures to nanoparticles. Methods Mol. Biol. 2011, 726:313-324.
38. Shan D., Xie Y., Ren G., Yang Z. Inhibitory effect of tungsten carbide nanoparticles on voltage-gated potassium currents of hippocampal CA1 neurous. Toxicol. Lett. 2012, 209(2):129-135.
39. Silverman W.R., de Rivero Vaccari J.P., Locovei S., Qiu F., Carlsson S.K., Scemes E., Keane R.W., Dahl G. The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J. Biol. Chem. 2009, 284(27):18143-18151.
40. +-channel responses during activation and damage in alveolar macrophages induced by quartz particles. J. Huazhong Univ. Sci. Technol. 2009, 29(4):404-408.
41. Terzano C., Di Stefano F., Conti V., Graziani E., Petroianni A. Air pollution ultrafine particles: toxicity beyond the lung. Eur. Rev. Med. Pharmacol. Sci. 2010, 14(10):809-821.
42. + channel responses during proliferation and activation in macrophages. J. Biol. Chem. 2003, 278(47):46307-46320.
43. + channels by endothelium-derived relaxing factors. Clin. Exp. Pharmacol. Physiol. 1999, 26(2):180-184.
44. Yamawaki H., Iwai N. Mechanisms underlying nano-sized air-pollution-mediated progression of atherosclerosis: carbon black causes cytotoxic injury/inflammation and inhibits cell growth in vascular endothelial cells. Circ. J. 2006, 70(1):129-140.
45. Yan J., Estévez M.C., Smith J.E., Wang K., He X., Wang L., Tan W. Dye-doped nanoparticles for bioanalysis. Nano. Today 2007, 2:44-50.
46. Yu S.P. Regulation and critical role of potassium homeostasis in apoptosis. Prog. Neurobiol. 2003, 70(4):363-386.
47. Yuan F., Dong P., Wang X., Fu X., Dai M., Zhang W. Toxicological effects of cigarette smoke on Ana-1 macrophages in vitro. Exp. Toxicol. Pathol. 2013, S0940-2993(13):31-36.