메뉴 건너뛰기




Volumn 13, Issue 7, 2014, Pages 933-946

UPC2 is universally essential for azole antifungal resistance in Candida albicans

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; FLUCONAZOLE; FUNGAL PROTEIN; TRANSCRIPTION FACTOR;

EID: 84903648333     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00221-13     Document Type: Article
Times cited : (47)

References (53)
  • 1
    • 2042454166 scopus 로고    scopus 로고
    • Determination of fungicidal activities against yeasts and molds: Lessons learned from bactericidal testing and the need for standardization
    • Pfaller MA, Sheehan DJ, Rex JH. 2004. Determination of fungicidal activities against yeasts and molds: lessons learned from bactericidal testing and the need for standardization. Clin. Microbiol. Rev. 17:268-280. http://dx.doi.org/10.1128/CMR.17.2.268-280.2004.
    • (2004) Clin. Microbiol. Rev. , vol.17 , pp. 268-280
    • Pfaller, M.A.1    Sheehan, D.J.2    Rex, J.H.3
  • 2
    • 79951972302 scopus 로고    scopus 로고
    • Genetic basis of antifungal drug resistance
    • Marie C, White TC. 2009. Genetic basis of antifungal drug resistance. Curr. Fungal Infect. Rep. 3:163-169. http://dx.doi.org/10.1007/s12281-009-0021-y.
    • (2009) Curr. Fungal Infect. Rep. , vol.3 , pp. 163-169
    • Marie, C.1    White, T.C.2
  • 4
    • 84903646378 scopus 로고    scopus 로고
    • Opportunistic mycoses
    • In Chisholm-Burns M, Wells B, Schwinghammer T, Malone P, Kolesar J, Rotschafer J, DiPiro J. (ed), 1st ed. McGraw-Hill Medical, New York, NY
    • Lewis RE, Rogers PD. 2007. Opportunistic mycoses, p 1600. In Chisholm-Burns M, Wells B, Schwinghammer T, Malone P, Kolesar J, Rotschafer J, DiPiro J. (ed), Pharmacotherapy principles and practice, 1st ed. McGraw-Hill Medical, New York, NY.
    • (2007) Pharmacotherapy principles and practice , pp. 1600
    • Lewis, R.E.1    Rogers, P.D.2
  • 5
    • 0029075535 scopus 로고
    • Epidemiology of nosocomial fungal infections, with emphasis on Candida species
    • Jarvis WR. 1995. Epidemiology of nosocomial fungal infections, with emphasis on Candida species. Clin. Infect. Dis. 20:1526-1530. http://dx. doi.org/10.1093/clinids/20.6.1526.
    • (1995) Clin. Infect. Dis. , vol.20 , pp. 1526-1530
    • Jarvis, W.R.1
  • 9
    • 0021279346 scopus 로고
    • Oral candidiasis in high-risk patients as the initial manifestation of the acquired immunodeficiency syndrome
    • Klein RS, Harris CA, Small CB, Moll B, Lesser M, Friedland GH. 1984. Oral candidiasis in high-risk patients as the initial manifestation of the acquired immunodeficiency syndrome. N. Engl. J. Med. 311:354-358. http://dx.doi.org/10.1056/NEJM198408093110602.
    • (1984) N. Engl. J. Med. , vol.311 , pp. 354-358
    • Klein, R.S.1    Harris, C.A.2    Small, C.B.3    Moll, B.4    Lesser, M.5    Friedland, G.H.6
  • 10
    • 0037197022 scopus 로고    scopus 로고
    • Antifungal drug resistance of pathogenic fungi
    • Kontoyiannis DP, Lewis RE. 2002. Antifungal drug resistance of pathogenic fungi. Lancet 359:1135-1144. http://dx.doi.org/10.1016/S0140-6736 (02)08162-X.
    • (2002) Lancet , vol.359 , pp. 1135-1144
    • Kontoyiannis, D.P.1    Lewis, R.E.2
  • 11
    • 47949096763 scopus 로고    scopus 로고
    • Candida infection in HIV positive patients 1985-2007
    • Traeder C, Kowoll S, Arasteh K. 2008. Candida infection in HIV positive patients 1985-2007. Mycoses 51(Suppl 2):58-61. http://dx.doi.org/10. 1111/j.1439-0507.2008.01574.x.
    • (2008) Mycoses , vol.51 , Issue.SUPPL. 2 , pp. 58-61
    • Traeder, C.1    Kowoll, S.2    Arasteh, K.3
  • 12
    • 0032882718 scopus 로고    scopus 로고
    • Antifungal agents: Mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance
    • Ghannoum MA, Rice LB. 1999. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin. Microbiol. Rev. 12:501-517.
    • (1999) Clin. Microbiol. Rev. , vol.12 , pp. 501-517
    • Ghannoum, M.A.1    Rice, L.B.2
  • 14
    • 20544432791 scopus 로고    scopus 로고
    • Cell wall integrity signaling in Saccharomyces cerevisiae
    • Levin DE. 2005. Cell wall integrity signaling in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 69:262-291. http://dx.doi.org/10.1128/MMBR. 69.2.262-291.2005.
    • (2005) Microbiol. Mol. Biol. Rev. , vol.69 , pp. 262-291
    • Levin, D.E.1
  • 15
    • 21344451158 scopus 로고    scopus 로고
    • Evolution of antifungal-drug resistance: Mechanisms and pathogen fitness
    • Anderson JB. 2005. Evolution of antifungal-drug resistance: mechanisms and pathogen fitness. Nat. Rev. Microbiol. 3:547-556. http://dx.doi.org /10.1038/nrmicro1179.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 547-556
    • Anderson, J.B.1
  • 16
    • 0142102609 scopus 로고    scopus 로고
    • Resistance and tolerance mechanisms to antifungal drugs in fungal pathogens
    • Sanglard D. 2003. Resistance and tolerance mechanisms to antifungal drugs in fungal pathogens. Mycologist 17(2):74-78. http://dx.doi.org/10. 1017/S0269915X03002076.
    • (2003) Mycologist , vol.17 , Issue.2 , pp. 74-78
    • Sanglard, D.1
  • 17
    • 0028001183 scopus 로고
    • Emergence of fluconazole-resistant strains of Candida albicans in patients with recurrent oropharyngeal candidosis and human immunodeficiency virus infection
    • Ruhnke M, Eigler A, Tennagen I, Geiseler B, Engelmann E, Trautmann M. 1994. Emergence of fluconazole-resistant strains of Candida albicans in patients with recurrent oropharyngeal candidosis and human immunodeficiency virus infection. J. Clin. Microbiol. 32:2092-2098.
    • (1994) J. Clin. Microbiol. , vol.32 , pp. 2092-2098
    • Ruhnke, M.1    Eigler, A.2    Tennagen, I.3    Geiseler, B.4    Engelmann, E.5    Trautmann, M.6
  • 18
    • 0031969879 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular factors that contribute to antifungal drug resistance
    • White TC, Marr KA, Bowden RA. 1998. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin. Microbiol. Rev. 11:382-402.
    • (1998) Clin. Microbiol. Rev. , vol.11 , pp. 382-402
    • White, T.C.1    Marr, K.A.2    Bowden, R.A.3
  • 19
    • 18244396070 scopus 로고    scopus 로고
    • Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes
    • MacPherson S, Akache B, Weber S, De Deken X, Raymond M, Turcotte B. 2005. Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes. Antimicrob. Agents Chemother. 49:1745-1752. http://dx.doi.org/10.1128 /AAC.49.5.1745-1752.2005.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 1745-1752
    • McPherson, S.1    Akache, B.2    Weber, S.3    De Deken, X.4    Raymond, M.5    Turcotte, B.6
  • 21
    • 0028942449 scopus 로고
    • Mode of action and resistance to azole antifungals associated with the formation of 14-α-methylergosta-8,24(28)-dien-3-β,6-α-diol
    • Kelly SL, Lamb DC, Corran AJ, Baldwin BC, Kelly DE. 1995. Mode of action and resistance to azole antifungals associated with the formation of 14-α-methylergosta-8,24(28)-dien-3-β,6-α-diol. Biochem. Biophys. Res. Commun. 207:910-915. http://dx.doi.org/10.1006/bbrc.1995.1272.
    • (1995) Biochem. Biophys. Res. Commun. , vol.207 , pp. 910-915
    • Kelly, S.L.1    Lamb, D.C.2    Corran, A.J.3    Baldwin, B.C.4    Kelly, D.E.5
  • 22
    • 4244112705 scopus 로고    scopus 로고
    • Reference method for broth dilution antifungal susceptibility testing of yeasts
    • NCCLS. 2nd ed. M27-A2. NCCLS, Wayne, PA
    • NCCLS. 2002. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard, 2nd ed. M27-A2. NCCLS, Wayne, PA.
    • (2002) Approved standard
  • 23
  • 24
    • 5044225522 scopus 로고    scopus 로고
    • The SAT1 flipper, an optimized tool for gene disruption in Candida albicans
    • Reuss O, Vik A, Kolter R, Morschhäuser J. 2004. The SAT1 flipper, an optimized tool for gene disruption in Candida albicans. Gene 341:119-127. http://dx.doi.org/10.1016/j.gene.2004.06.021.
    • (2004) Gene , vol.341 , pp. 119-127
    • Reuss, O.1    Vik, A.2    Kolter, R.3    Morschhäuser, J.4
  • 25
    • 47049101245 scopus 로고    scopus 로고
    • A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate
    • Dunkel N, Liu TT, Barker KS, Homayouni R, Morschhäuser J, Rogers PD. 2008. A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate. Eukaryot. Cell 7:1180-1190. http://dx.doi.org/10.1128/EC.00103-08.
    • (2008) Eukaryot. Cell , vol.7 , pp. 1180-1190
    • Dunkel, N.1    Liu, T.T.2    Barker, K.S.3    Homayouni, R.4    Morschhäuser, J.5    Rogers, P.D.6
  • 26
    • 84882785474 scopus 로고    scopus 로고
    • Isolation of yeast genomic DNA for Southern blot analysis
    • 2006:pii:pdb. prot4149
    • Amberg DC, Burke DJ, Strathern JN. 2006. Isolation of yeast genomic DNA for Southern blot analysis. CSH Protoc. 2006:pii:pdb. prot4149. http://dx.doi.org/10.1101/pdb.prot4149.
    • (2006) CSH Protoc.
    • Amberg, D.C.1    Burke, D.J.2    Strathern, J.N.3
  • 27
    • 0025362399 scopus 로고
    • A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae
    • Schmitt ME, Brown TA, Trumpower BL. 1990. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 18:3091-3092. http://dx.doi.org/10.1093/nar/18.10.3091.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3091-3092
    • Schmitt, M.E.1    Brown, T.A.2    Trumpower, B.L.3
  • 28
    • 84867168091 scopus 로고    scopus 로고
    • Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans
    • Flowers SA, Barker KS, Berkow EL, Toner G, Chadwick SG, Gygax SE, Morschhauser J, Rogers PD. 2012. Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans. Eukaryot. Cell 11:1289-1299. http://dx.doi.org /10.1128/EC.00215-12.
    • (2012) Eukaryot. Cell , vol.11 , pp. 1289-1299
    • Flowers, S.A.1    Barker, K.S.2    Berkow, E.L.3    Toner, G.4    Chadwick, S.G.5    Gygax, S.E.6    Morschhauser, J.7    Rogers, P.D.8
  • 30
    • 11144270183 scopus 로고    scopus 로고
    • TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2
    • Coste AT, Karababa M, Ischer F, Bille J, Sanglard D. 2004. TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2. Eukaryot. Cell 3:1639-1652. http://dx.doi.org/10.1128/EC.3.6. 1639-1652.2004.
    • (2004) Eukaryot. Cell , vol.3 , pp. 1639-1652
    • Coste, A.T.1    Karababa, M.2    Ischer, F.3    Bille, J.4    Sanglard, D.5
  • 31
    • 37349095258 scopus 로고    scopus 로고
    • The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans
    • Morschhäuser J, Barker KS, Liu TT, Blaß-Warmuth J, Homayouni R, Rogers PD. 2007. The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans. PLoS Pathog. 3:e164. http://dx.doi.org/10.1371/journal.ppat. 0030164.
    • (2007) PLoS Pathog. , vol.3
    • Morschhäuser, J.1    Barker, K.S.2    Liu, T.T.3    Blaß-Warmuth, J.4    Homayouni, R.5    Rogers, P.D.6
  • 32
    • 80053187522 scopus 로고    scopus 로고
    • The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicans
    • Sasse C, Schillig R, Dierolf F, Weyler M, Schneider S, Mogavero S, Rogers PD, Morschhäuser J. 2011. The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicans. PLoS One 6:e25623. http://dx.doi.org/10.1371 /journal.pone.0025623.
    • (2011) PLoS One , vol.6
    • Sasse, C.1    Schillig, R.2    Dierolf, F.3    Weyler, M.4    Schneider, S.5    Mogavero, S.6    Rogers, P.D.7    Morschhäuser, J.8
  • 33
    • 79961093145 scopus 로고    scopus 로고
    • Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1
    • Schubert S, Popp C, Rogers PD, Morschhäuser J. 2011. Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1. Eukaryot. Cell 10:1110-1121. http://dx. doi.org/10.1128/EC.05100-11.
    • (2011) Eukaryot. Cell , vol.10 , pp. 1110-1121
    • Schubert, S.1    Popp, C.2    Rogers, P.D.3    Morschhäuser, J.4
  • 36
    • 11144308844 scopus 로고    scopus 로고
    • Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism
    • Silver PM, Oliver BG, White TC. 2004. Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism. Eukaryot. Cell 3:1391-1397. http://dx.doi.org/10.1128/EC.3.6.1391-1397. 2004.
    • (2004) Eukaryot. Cell , vol.3 , pp. 1391-1397
    • Silver, P.M.1    Oliver, B.G.2    White, T.C.3
  • 37
    • 37549020764 scopus 로고    scopus 로고
    • cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p
    • Oliver BG, Song JL, Choiniere JH, White TC. 2007. cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p. Eukaryot. Cell 6:2231-2239. http: //dx.doi.org/10.1128/EC.00331-06.
    • (2007) Eukaryot. Cell , vol.6 , pp. 2231-2239
    • Oliver, B.G.1    Song, J.L.2    Choiniere, J.H.3    White, T.C.4
  • 38
    • 73849109145 scopus 로고    scopus 로고
    • An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans
    • Heilmann CJ, Schneider S, Barker KS, Rogers PD, Morschhäuser J. 2010. An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans. Antimicrob. Agents Chemother. 54:353-359. http://dx.doi. org/10.1128/AAC.01102-09.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 353-359
    • Heilmann, C.J.1    Schneider, S.2    Barker, K.S.3    Rogers, P.D.4    Morschhäuser, J.5
  • 39
    • 78751695581 scopus 로고    scopus 로고
    • An A643V amino acid substitution in Upc2p contributes to azole resistance in well-characterized clinical isolates of Candida albicans
    • Hoot SJ, Smith AR, Brown RP, White TC. 2011. An A643V amino acid substitution in Upc2p contributes to azole resistance in well-characterized clinical isolates of Candida albicans. Antimicrob. Agents Chemother. 55: 940-942. http://dx.doi.org/10.1128/AAC.00995-10.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 940-942
    • Hoot, S.J.1    Smith, A.R.2    Brown, R.P.3    White, T.C.4
  • 40
    • 0030757227 scopus 로고    scopus 로고
    • Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus
    • White TC. 1997. Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrob. Agents Chemother. 41:1482-1487.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1482-1487
    • White, T.C.1
  • 41
    • 0037378017 scopus 로고    scopus 로고
    • Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates
    • Rogers PD, Barker KS. 2003. Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates. Antimicrob. Agents Chemother. 47:1220-1227. http://dx.doi.org/10.1128/AAC.47.4. 1220-1227.2003.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1220-1227
    • Rogers, P.D.1    Barker, K.S.2
  • 42
    • 84868087578 scopus 로고    scopus 로고
    • The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans
    • Sasse C, Dunkel N, Schafer T, Schneider S, Dierolf F, Ohlsen K, Morschhäuser J. 2012. The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans. Mol. Microbiol. 86:539-556. http://dx.doi.org/10.1111/j.1365-2958.2012.08210.x.
    • (2012) Mol. Microbiol. , vol.86 , pp. 539-556
    • Sasse, C.1    Dunkel, N.2    Schafer, T.3    Schneider, S.4    Dierolf, F.5    Ohlsen, K.6    Morschhäuser, J.7
  • 43
    • 0031024163 scopus 로고    scopus 로고
    • Resistance to fluconazole and crossresistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol 5,6-desaturation
    • Kelly SL, Lamb DC, Kelly DE, Manning NJ, Loeffler J, Hebart H, Schumacher U, Einsele H. 1997. Resistance to fluconazole and crossresistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol 5,6-desaturation. FEBS Lett. 400:80-82. http: //dx.doi.org/10.1016/S0014-5793(96)01360-9.
    • (1997) FEBS Lett. , vol.400 , pp. 80-82
    • Kelly, S.L.1    Lamb, D.C.2    Kelly, D.E.3    Manning, N.J.4    Loeffler, J.5    Hebart, H.6    Schumacher, U.7    Einsele, H.8
  • 44
    • 33744493394 scopus 로고    scopus 로고
    • Candida resistance and its clinical relevance
    • Klepser ME. 2006. Candida resistance and its clinical relevance. Pharmacotherapy 26:68S-75S. http://dx.doi.org/10.1592/phco.26.6part2.68S.
    • (2006) Pharmacotherapy , vol.26
    • Klepser, M.E.1
  • 45
    • 0024468971 scopus 로고
    • Defective sterol C5-6 desaturation and azole resistance: A new hypothesis for the mode of action of azole antifungals
    • Watson PF, Rose ME, Ellis SW, England H, Kelly SL. 1989. Defective sterol C5-6 desaturation and azole resistance: a new hypothesis for the mode of action of azole antifungals. Biochem. Biophys. Res. Commun. 164:1170-1175. http://dx.doi.org/10.1016/0006-291X(89)91792-0.
    • (1989) Biochem. Biophys. Res. Commun. , vol.164 , pp. 1170-1175
    • Watson, P.F.1    Rose, M.E.2    Ellis, S.W.3    England, H.4    Kelly, S.L.5
  • 46
    • 0033807662 scopus 로고    scopus 로고
    • Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors
    • Henry KW, Nickels JT, Edlind TD. 2000. Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors. Antimicrob. Agents Chemother. 44:2693-2700. http://dx.doi.org/10.1128 /AAC.44.10.2693-2700.2000.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 2693-2700
    • Henry, K.W.1    Nickels, J.T.2    Edlind, T.D.3
  • 47
    • 33750601648 scopus 로고    scopus 로고
    • Unexpected link between iron and drug resistance of Candida spp.: Iron depletion enhances membrane fluidity and drug diffusion, leading to drugsusceptible cells
    • Prasad T, Chandra A, Mukhopadhyay CK, Prasad R. 2006. Unexpected link between iron and drug resistance of Candida spp.: iron depletion enhances membrane fluidity and drug diffusion, leading to drugsusceptible cells. Antimicrob. Agents Chemother. 50:3597-3606. http://dx. doi.org/10.1128/AAC.00653-06.
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 3597-3606
    • Prasad, T.1    Chandra, A.2    Mukhopadhyay, C.K.3    Prasad, R.4
  • 48
    • 0036251099 scopus 로고    scopus 로고
    • Conditions influencing the in vitro antifungal activity of lactoferrin combined with antimycotics against clinical isolates of Candida. Impact on the development of buccal preparations of lactoferrin
    • Kuipers ME, Beljaars L, Van Beek N, De Vries HG, Heegsma J, Van Den Berg JJ, Meijer DK, Swart PJ. 2002. Conditions influencing the in vitro antifungal activity of lactoferrin combined with antimycotics against clinical isolates of Candida. Impact on the development of buccal preparations of lactoferrin. APMIS 110:290-298. http://dx.doi.org/10.1034/j. 1600-0463.2002.100403.x.
    • (2002) APMIS , vol.110 , pp. 290-298
    • Kuipers, M.E.1    Beljaars, L.2    Van Beek, N.3    De Vries, H.G.4    Heegsma, J.5    Van Den Berg, J.J.6    Meijer, D.K.7    Swart, P.J.8
  • 49
    • 0032707616 scopus 로고    scopus 로고
    • Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates
    • Kuipers ME, de Vries HG, Eikelboom MC, Meijer DK, Swart PJ. 1999. Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates. Antimicrob. Agents Chemother. 43:2635-2641.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 2635-2641
    • Kuipers, M.E.1    de Vries, H.G.2    Eikelboom, M.C.3    Meijer, D.K.4    Swart, P.J.5
  • 50
    • 51149102074 scopus 로고    scopus 로고
    • Human recombinant lactoferrin acts synergistically with antimicrobials commonly used in neonatal practice against coagulase-negative staphylococci and Candida albicans causing neonatal sepsis
    • Venkatesh MP, Rong L. 2008. Human recombinant lactoferrin acts synergistically with antimicrobials commonly used in neonatal practice against coagulase-negative staphylococci and Candida albicans causing neonatal sepsis. J. Med. Microbiol. 57:1113-1121. http://dx.doi.org/10. 1099/jmm.0.2008/001263-0.
    • (2008) J. Med. Microbiol. , vol.57 , pp. 1113-1121
    • Venkatesh, M.P.1    Rong, L.2
  • 52
    • 84867911841 scopus 로고    scopus 로고
    • A defect in iron uptake enhances the susceptibility of Cryptococcus neoformans to azole antifungal drugs
    • Kim J, Cho YJ, Do E, Choi J, Hu G, Cadieux B, Chun J, Lee Y, Kronstad JW, Jung WH. 2012. A defect in iron uptake enhances the susceptibility of Cryptococcus neoformans to azole antifungal drugs. Fungal Genet. Biol. 49:955-966. http://dx.doi.org/10.1016/j.fgb.2012.08.006.
    • (2012) Fungal Genet. Biol. , vol.49 , pp. 955-966
    • Kim, J.1    Cho, Y.J.2    Do, E.3    Choi, J.4    Hu, G.5    Cadieux, B.6    Chun, J.7    Lee, Y.8    Kronstad, J.W.9    Jung, W.H.10
  • 53
    • 0028006489 scopus 로고
    • Resistance of Candida albicans to fluconazole during treatment of oropharyngeal candidiasis in a patient with AIDS: Documentation by in vitro susceptibility testing and DNA subtype analysis
    • Redding S, Smith J, Farinacci G, Rinaldi M, Fothergill A, Rhine-Chalberg J, Pfaller M. 1994. Resistance of Candida albicans to fluconazole during treatment of oropharyngeal candidiasis in a patient with AIDS: documentation by in vitro susceptibility testing and DNA subtype analysis. Clin. Infect. Dis. 18:240-242. http://dx.doi.org/10.1093/clinids/18.2. 240.
    • (1994) Clin. Infect. Dis. , vol.18 , pp. 240-242
    • Redding, S.1    Smith, J.2    Farinacci, G.3    Rinaldi, M.4    Fothergill, A.5    Rhine-Chalberg, J.6    Pfaller, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.