SHH, WNT, and NOTCH pathways in medulloblastoma: When cancer stem cells maintain self-renewal and differentiation properties

Child's Nervous System

Volumn 30, Issue 7, 2014, Pages 1165-1172

  Mascaro Cordeiro, Bruna ^a   Dias Oliveira, Indhira ^a   De Seixas Alves, Maria Teresa ^a   Saba Silva, Nasjla ^a   Capellano, Andrea M ^a   Cavalheiro, Sergio ^a   Dastoli, Patrícia ^a   Toledo, Silvia Regina Caminada ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Gene expression; Medulloblastoma; Molecular targets; NOTCH; SHH; WNT

Indexed keywords

APC PROTEIN; NOTCH RECEPTOR; NOTCH2 RECEPTOR; PROTEIN PATCHED 1; PROTEIN PATCHED 2; RNA; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR HES 1; WNT PROTEIN; SHH PROTEIN, HUMAN; TRANSCRIPTOME;

ARTICLE; CANCER STEM CELL; CELL DIFFERENTIATION; CELL RENEWAL; CHILD; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFANT; MALE; MEDULLOBLASTOMA; NEWBORN; ONCOGENE; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; CEREBELLUM TUMOR; KAPLAN MEIER METHOD; METABOLISM; MORTALITY; PATHOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; HEDGEHOG PROTEINS; HUMANS; INFANT; INFANT, NEWBORN; KAPLAN-MEIER ESTIMATE; MALE; MEDULLOBLASTOMA; NEOPLASTIC STEM CELLS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTOME; WNT PROTEINS;

EID: 84903643715     PISSN: 02567040     EISSN: 14330350     Source Type: Journal    
DOI: 10.1007/s00381-014-2403-x     Document Type: Article

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