Keratinocyte detachment-differentiation connection revisited, or Anoikis-Pityriasi Nexus Redux

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Banno, Tomohiro ^a   Blumenberg, Miroslav ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMITOTIC AGENT; MARKER; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; BASAL CELL; BASEMENT MEMBRANE; CELL ANCHORAGE; CELL COMPONENT; CELL CYCLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL MOTILITY; CELL SUSPENSION; CONTROLLED STUDY; DESMOSOMAL GENE; ENZYME INHIBITION; EPIDERMIS; GENE; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; KERATINIZATION; KERATINOCYTE; MELANOSOME; MITOCHONDRIAL GENE; MITOCHONDRION; NEWBORN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; OVERLAPPING GENE; RNA SPLICING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; BIOLOGY; CELL ADHESION; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY;

ANIMALS; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; KERATINOCYTES; MICE; MOLECULAR SEQUENCE ANNOTATION;

EID: 84903544427     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100279     Document Type: Article

References (50)

1. Lopez-Pajares V, Yan K, Zarnegar BJ, Jameson KL, Khavari PA (2013) Genetic pathways in disorders of epidermal differentiation. Trends Genet 29: 31-40. doi: 10.1016/j.tig.2012.1010.1005.
2. Feingold KR, Elias PM (2013) Role of lipids in the formation and maintenance of the cutaneous permeability barrier. Biochim Biophys Acta 18: 00249-00247.
3. Perdigoto CN, Valdes VJ, Bardot ES, Ezhkova E (2014) Epigenetic regulation of epidermal differentiation. Cold Spring Harb Perspect Med 4(2). a015263. doi: 015210.011101/cshperspect.a015263.
4. Bikle DD, Xie Z, Tu CL (2012) Calcium regulation of keratinocyte differentiation. Expert Rev Endocrinol Metab 7: 461-472.
5. Bertrand-Vallery V, Belot N, Dieu M, Delaive E, Ninane N, et al. (2010) Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor. PLoS One 5: e10462. doi: 10410.11371/journal.pone.0010462.
6. Li D, Turi TG, Schuck A, Freedberg IM, Khitrov G, et al. (2001) Rays and arrays: the transcriptional program in the response of human epidermal keratinocytes to UVB illumination. Faseb J 15: 2533-2535.
7. Hamanaka RB, Glasauer A, Hoover P, Yang S, Blatt H, et al. (2013) Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development. Sci Signal 6: ra8. doi: 10.1126/scisignal.2003638.
8. Ura H, Takeda F, Okochi H (2004) An in vitro outgrowth culture system for normal human keratinocytes. J Dermatol Sci 35: 19-28. (Pubitemid 38759737)
9. Walsh R, Blumenberg M (2011) Specific and shared targets of ephrin A signaling in epidermal keratinocytes. J Biol Chem 286: 9419-9428.
10. Gazel A, Banno T, Walsh R, Blumenberg M (2006) Inhibition of JNK promotes differentiation of epidermal keratinocytes. J Biol Chem 28: 28.
11. Adams JC, Watt FM (1989) Fibronectin inhibits the terminal differentiation of human keratinocytes. Nature 340: 307-309. (Pubitemid 19189690)
12. Adams JC, Watt FM (1990) Changes in keratinocyte adhesion during terminal differentiation: reduction in fibronectin binding precedes alpha 5 beta 1 integrin loss from the cell surface. Cell 63: 425-435.
13. Margadant C, Charafeddine RA, Sonnenberg A (2010) Unique and redundant functions of integrins in the epidermis. Faseb J 24: 4133-4152. doi: 4110.1096/fj.4109-151449.
14. Watt FM (2002) Role of integrins in regulating epidermal adhesion, growth and differentiation. Embo J 21: 3919-3926.
15. Tsuruta D, Hashimoto T, Hamill KJ, Jones JC (2011) Hemidesmosomes and focal contact proteins: functions and cross-talk in keratinocytes, bullous diseases and wound healing. J Dermatol Sci 62: 1-7. doi: 10.1016/j.jdermsci. 2011.1001.1005.
16. Hamada T, Tsuruta D, Fukuda S, Ishii N, Teye K, et al. (2013) How do keratinizing disorders and blistering disorders overlap? Exp Dermatol 22: 83-87. doi: 10.1111/exd.12021.
17. Tran QT, Kennedy LH, Leon Carrion S, Bodreddigari S, Goodwin SB, et al. (2012) EGFR regulation of epidermal barrier function. Physiol Genomics 44: 455-469.
18. Radoja N, Gazel A, Banno T, Yano S, Blumenberg M (2006) Transcriptional Profiling of Epidermal Differentiation. Physiol Genomics 27: 65-78. (Pubitemid 44511826)
19. Yin T, Green KJ (2004) Regulation of desmosome assembly and adhesion. Semin Cell Dev Biol 15: 665-677. (Pubitemid 39550246)
20. Morris GM, Hopewell JW (1987) Cell population kinetics in pig epidermis: further studies. Cell Tissue Kinet 20: 161-169.
21. Stojadinovic O, Lee B, Vouthounis C, Vukelic S, Pastar I, et al. (2007) Novel genomic effects of glucocorticoids in epidermal keratinocytes: inhibition of apoptosis, interferon-gamma pathway, and wound healing along with promotion of terminal differentiation. J Biol Chem 282: 4021-4034. (Pubitemid 47084434)
22. Vukelic S, Stojadinovic O, Pastar I, Vouthounis C, Krzyzanowska A, et al. (2010) Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. J Biol Chem 285: 1980-1988. doi: 1910.1074/jbc.M1109.016741.
23. Wu N, Sulpice E, Obeid P, Benzina S, Kermarrec F, et al. (2012) The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentiation. PLoS One 7: e45761. doi: 45710.41371/journal.pone. 0045761.
24. Harmon RM, Simpson CL, Johnson JL, Koetsier JL, Dubash AD, et al. (2013) Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation. J Clin Invest 123: 1556-1570. doi: 1510.1172/JCI65220.
25. Efimova T, Broome AM, Eckert RL (2003) A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation. J Biol Chem 278: 34277-34285. (Pubitemid 37553271)
26. Han B, Rorke EA, Adhikary G, Chew YC, Xu W, et al. (2012) Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation. PLoS One 7: e36941.
27. Blumenberg M, Connolly DM, Freedberg IM (1992) Regulation of keratin gene expression: the role of the nuclear receptors for retinoic acid, thyroid hormone and vitamin D3. J Invest Dermatol 98: 42S-49S.
28. Darmon M, Blumenberg M (1993) Retinoic acid in epithelial and epidermal differentiation. In: Darmon M, Blumenberg M, editors. Molecular Biology of the Skin: The Keratinocyte. New York: Academic Press, Inc. pp. 181-198.
29. Lee DD, Stojadinovic O, Krzyzanowska A, Vouthounis C, Blumenberg M, et al. (2009) Retinoid-responsive transcriptional changes in epidermal keratinocytes. J Cell Physiol 220: 427-439.
30. Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, et al. (2013) Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature 493: 231-235. doi: 210.1038/nature11661.
31. Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, et al. (2012) Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes Dev 26: 338-343. doi: 310.1101/gad.182121.182111.
32. Jensen MA, Wilkinson JE, Krainer AR (2014) Splicing factor SRSF6 promotes hyperplasia of sensitized skin. Nat Struct Mol Biol 21: 189-197. doi: 110.1038/nsmb.2756.
33. Lee JS, Yoon HK, Sohn KC, Back SJ, Kee SH, et al. (2009) Expression of N-terminal truncated desmoglein 3 (deltaNDg3) in epidermis and its role in keratinocyte differentiation. Exp Mol Med 41: 42-50.
34. Taddei ML, Giannoni E, Fiaschi T, Chiarugi P (2012) Anoikis: an emerging hallmark in health and diseases. J Pathol 226: 380-393. doi: 310.1002/path.3000.
35. Efimova T (2010) p38delta mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis. Cell Cycle 9: 498-405.
36. Lippens S, Denecker G, Ovaere P, Vandenabeele P, Declercq W (2005) Death penalty for keratinocytes: apoptosis versus cornification. Cell Death Differ 12: 1497-1508. (Pubitemid 41553986)
37. Tiberio R, Marconi A, Fila C, Fumelli C, Pignatti M, et al. (2002) Keratinocytes enriched for stem cells are protected from anoikis via an integrin signaling pathway in a Bcl-2 dependent manner. FEBS Lett 524: 139-144. (Pubitemid 34804849)
38. Marconi A, Atzei P, Panza C, Fila C, Tiberio R, et al. (2004) FLICE/caspase-8 activation triggers anoikis induced by beta1-integrin blockade in human keratinocytes. J Cell Sci 117: 5815-5823. (Pubitemid 40123948)
39. Marconi A, Dallaglio K, Lotti R, Vaschieri C, Truzzi F, et al. (2007) Survivin identifies keratinocyte stem cells and is downregulated by anti-beta1 integrin during anoikis. Stem Cells 25: 149-155. (Pubitemid 46052985)
40. Lowes MA, Suarez-Farinas M, Krueger JG (2014) Immunology of psoriasis. Annu Rev Immunol 32:227-55.: 10.1146/annurev-immunol-032713-120225.
41. Chiricozzi A, Nograles KE, Johnson-Huang LM, Fuentes-Duculan J, Cardinale I, et al. (2014) IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model. PLoS One 9: e90284. doi: 90210.91371/journal.pone.0090284. eCollection 0092014.
42. Pyeon D (2013) Human Keratinocyte Cultures in the Investigation of Early Steps of Human Papillomavirus Infection. Methods Mol Biol 27: 27.
43. Shen B, Delaney MK, Du X (2012) Inside-out, outside-in, and inside-outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction. Curr Opin Cell Biol 24: 600-606. doi: 610.1016/j.ceb.2012.1008.1011.
44. Campbell ID, Humphries MJ (2011) Integrin structure, activation, and interactions. Cold Spring Harb Perspect Biol 3(3). a004994. doi: 004910.001101/cshperspect.a004994.
45. Banno T, Adachi M, Mukkamala L, Blumenberg M (2003) Unique keratinocyte-specific effects of interferon-gamma that protect skin from viruses, identified using transcriptional profiling. Antivir Ther 8: 541-554. (Pubitemid 38057100)
46. Banno T, Gazel A, Blumenberg M (2005) Pathway-specific Profiling Identifies the NF-{kappa}B-dependent Tumor Necrosis Factor {alpha}-regulated Genes in Epidermal Keratinocytes. J Biol Chem 280: 18973-18980. (Pubitemid 41379601)
47. Mahadevappa M, Warrington JA (1999) A high-density probe array sample preparation method using 10- to 100-fold fewer cells. Nat Biotechnol 17: 1134-1136. (Pubitemid 29533558)
48. Mimoso C, Lee DD, Zavadil J, Tomic-Canic M, Blumenberg M (2013) Analysis and Meta-analysis of Transcriptional Profiling in Human Epidermis. Methods Mol Biol 3: 3.
49. Huang da W, Sherman BT, Lempicki RA (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13.
50. Barrett T, Suzek TO, Troup DB, Wilhite SE, Ngau WC, et al. (2005) NCBI GEO: mining millions of expression profiles-database and tools. Nucleic Acids Res 33: D562-566. (Pubitemid 40207937)