Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor

Journal of Biological Chemistry

Volumn 285, Issue 3, 2010, Pages 1980-1988

  Vukelic, Sasa ^a   Stojadinovic, Olivera ^b   Pastar, Irena ^b   Vouthounis, Constantinos ^a   Krzyzanowska, Agata ^a   Das, Sharmistha ^c   Samuels, Herbert H ^c   Tomic Canic, Marjana ^a  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE MEDIUMS; EX-VIVO; FARNESYL PYROPHOSPHATES; FARNESYLATION; GLUCOCORTICOID RECEPTOR; IN-CELL; IN-VITRO; KERATINOCYTE MIGRATION; MEVALONATE PATHWAY; MOLECULAR MECHANISM; NUCLEAR HORMONE RECEPTOR; NUCLEAR TRANSLOCATIONS; PLEIOTROPIC EFFECTS; REDUCTASE INHIBITORS; STATINS; SYNTHETASES; WOUND HEALING;

SYNTHESIS (CHEMICAL);

CELL CULTURE;

COMPACTIN; CYTOKERATIN 6; FARNESYL DIPHOSPHATE; GLUCOCORTICOID RECEPTOR; ZARAGOZIC ACID A; DRUG DERIVATIVE; ENZYME INHIBITOR; FUSED HETEROCYCLIC RINGS; GLUCOCORTICOID; ISOPRENOID PHOSPHATE; LIGAND; MEVINOLIN; SESQUITERPENE; SQUALENE SYNTHASE; TRICARBOXYLIC ACID;

ARTICLE; CELL MIGRATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CULTURE MEDIUM; EPITHELIZATION; EX VIVO STUDY; GENE REPRESSION; GENETIC TRANSFECTION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INHIBITION KINETICS; KERATINOCYTE; PLASMID; PRIORITY JOURNAL; SKIN; SYNTHESIS; WESTERN BLOTTING; WOUND HEALING; ANIMAL; CATTLE; CELL LINE; CELL MOTION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROMOTER REGION; SIGNAL TRANSDUCTION;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CATTLE; CELL LINE; CELL MOVEMENT; ENZYME INHIBITORS; EPITHELIAL CELLS; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; KERATIN-6; KERATINOCYTES; LIGANDS; LOVASTATIN; POLYISOPRENYL PHOSPHATES; PROMOTER REGIONS, GENETIC; RECEPTORS, GLUCOCORTICOID; SESQUITERPENES; SIGNAL TRANSDUCTION; TRICARBOXYLIC ACIDS; WOUND HEALING;

EID: 76249083086     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.016741     Document Type: Article

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